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Journal / Bioengineering / İnsan Kaynaklı Pluripotent Kök Hücrelerden…
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Bioengineering

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JoVE Journal Bioengineering
İnsan Kaynaklı Pluripotent Kök Hücrelerden Üretilen İzojenik Böbrek Glomerulus Çipi
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İnsan Kaynaklı Pluripotent Kök Hücrelerden Üretilen İzojenik Böbrek Glomerulus Çipi

Article DOI: 10.3791/63821-v • 10:23 min • November 4th, 2022
November 4th, 2022 •
1, 1,2,3,4
1Department of Biomedical Engineering, Pratt School of Engineering, Duke University, 2Department of Medicine, Division of Nephrology, Duke University School of Medicine, 3Department of Cell Biology, Duke University, 4Center for Biomolecular and Tissue Engineering, Duke University

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Burada, insan kaynaklı pluripotent kök hücrelerden farklılaşan genetik olarak eşleşen epitel ve vasküler endotel hücrelerini entegre ederek böbrek glomerüler filtrasyon bariyerinin yapısını ve işlevini özetleyen kişiselleştirilmiş bir çip üzerinde organ sistemi tasarlamak için bir protokol sunulmaktadır. Bu biyomühendislik sistemi, böbrek hassas tıbbını ve ilgili uygulamaları ilerletebilir.

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