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Cultivos organotípicos de explante retiniano de mono macaco
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Cultivos organotípicos de explante retiniano de mono macaco

Article DOI: 10.3791/64178-v • 10:32 min • August 24th, 2022
August 24th, 2022 •
1, 1, 1, 1, 2, 1
1Yunnan Eye Institute & Key Laboratory of Yunnan Province, Yunnan Eye Disease Clinical Medical Center, Affiliated Hospital of Yunnan University, Yunnan University, 2Institute for Ophthalmic Research, Eberhard-Karls-Universität Tübingen

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Los explantes retinianos obtenidos de macacos de tipo silvestre se cultivaron in vitro. La degeneración retiniana y la vía de señalización cGMP-PKG se indujeron utilizando el inhibidor de la PDE6 zaprinast. La acumulación de cGMP en los explantes a diferentes concentraciones de zaprinast se verificó mediante inmunofluorescencia.

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Neurociencia Número 186
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