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JoVE Journal Behavior
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Assessing Dominant-Submissive Behavior in Adult Rats Following Traumatic Brain Injury

Article DOI: 10.3791/64548-v • 03:56 min • December 16th, 2022
December 16th, 2022 •
*1, *2, 1, 1, 3, 1, 1, 4, 1, 1
1Division of Anesthesiology and Critical Care, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, 2Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, 3Department of Biochemistry and Physiology of the Faculty of Biology and Ecology, Oles Gonchar of the Dnipro National University, 4Department of Ophthalmology, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev
* These authors contributed equally

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Summary
Automatic Translation

The present protocol describes a rat model of fluid percussion-induced traumatic brain injury followed by a series of behavioral tests to understand the development of dominant and submissive behavior. Using this model of traumatic brain injury in conjunction with specific behavioral tests enables the study of social impairments following brain injury.

Tags

Dominant-submissive Behavior Traumatic Brain Injury Investigation Food Competition Test Reproducibility Analyze Behavior Mania And Depression Early Life Stress Maternal Separation Adult Rats Neurological Severity Score Anesthetizing Immobilization Craniotomy Fluid Percussion Device Sham Operated Rats
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