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Journal / Immunology and Infection / Редактирование генов первичных В-клеток…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Редактирование генов первичных В-клеток макак-резусов
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Редактирование генов первичных В-клеток макак-резусов

Article DOI: 10.3791/64858-v • 09:53 min • February 10th, 2023
February 10th, 2023 •
1, 2, 2, 3,5, 1, 1,6, 1, 2, 1,4
1Laboratory of Molecular Immunology, The Rockefeller University, 2Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 3Laboratory of Retrovirology, The Rockefeller University, 4Howard Hughes Medical Institute, The Rockefeller University, 5Laboratory of Applied Virology and Precision Medicine, King Abdullah University of Science and Technology (KAUST), 6Vaccine and Immunotherapy Center, Wistar Institute

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Мы представляем метод культивирования и редактирования генов первичных В-клеток макак-резусов с использованием CRISPR/Cas9 и рекомбинантного аденоассоциированного вируса серотипа 6 для изучения терапии В-клетками.

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В этом месяце в JoVE выпуск 192 В-клетки редактирование генов геномная инженерия CRISPR/Cas9 аденоассоциированный вирус макака-резус приматы клеточная терапия
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