Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Biology / Demonstration of the DNA Fiber Assay for…
JoVE Journal
Biology

A subscription to JoVE is required to view this content. Sign in or start your free trial.

JoVE Journal Biology
Demonstration of the DNA Fiber Assay for Investigating DNA Damage and Repair Dynamics Induced by Nanoparticles
Staining of Sub-Retinal Pigment Epithelium (RPE) Deposits (Video) | JoVE
Journal (Biology)
Staining of Sub-Retinal Pigment Epithelium (RPE) Deposits (Video) | JoVE
Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling
Journal (Biology)
Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling
 

Demonstration of the DNA Fiber Assay for Investigating DNA Damage and Repair Dynamics Induced by Nanoparticles

Article DOI: 10.3791/64903-v • 13:09 min • March 3rd, 2023
March 3rd, 2023 •
1, 1,2, 1
1Department of Biomedical Sciences, University of Illinois College of Medicine Rockford, 2Department of Health Sciences Education, University of Illinois College of Medicine Rockford

Chapters

Summary
Automatic Translation

The methodology assists in the analysis of variation in DNA replication dynamics in the presence of nanoparticles. Different methodologies can be adopted based on the cytotoxicity level of the material of interest. In addition, a description of the image analysis is provided to help in DNA fiber analysis.

Tags

DNA Fiber Assay Investigating DNA Damage Repair Dynamics Nanoparticles Nanotoxicity DNA Replication DNA Repair Chromatin Dynamics Therapeutic Material Efficacy Off-target Effect Chemotherapeutic Agents Health Impact Assessment Nanomedicine Safety Evaluation
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter