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Optogenetic Stimulation of the Auditory Nerve
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Optogenetic Stimulation of the Auditory Nerve
DOI:

10:53 min

October 08, 2014

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Chapters

  • 00:05Title
  • 01:54Preparing the μLED Stimulator
  • 03:31Cochleostomy for Transcochlear Stimulation
  • 05:12Implanting the Stimulator and Recording Optogenetic Auditory Brainstem Responses (oABR)
  • 07:40Recording Optically Evoked Local Field Potentials
  • 08:21Results: Comapring Auditory Brainstem Response and Signal Propagation from oABR
  • 09:46Conclusion

Summary

Automatic Translation

Cochlear implants (CIs) enable hearing by direct electrical stimulation of the auditory nerve. However, poor frequency and intensity resolution limits the quality of hearing with CIs. Here we describe optogenetic stimulation of the auditory nerve in mice as an alternative strategy for auditory research and developing future CIs.

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