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Scaling of Engineered Vascular Grafts Using 3D Printed Guides and the Ring Stacking Method
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Scaling of Engineered Vascular Grafts Using 3D Printed Guides and the Ring Stacking Method
DOI:

09:38 min

March 27, 2017

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Chapters

  • 00:05Title
  • 00:353D Printed Insert and Custom Silicone Molded Plate Preparation
  • 02:20Fibrin Hydrogel Preparation, Smooth Muscle Cell Seeding and Plate Maintenance
  • 04:42Vascular Construct Assembly and Maintenance
  • 07:36Results: Representative Vessel Construct Analyses
  • 08:54Conclusion

Summary

Automatic Translation

Scalable engineered blood vessels would improve clinical applicability. Using easily sizable 3D-printed guides, rings of vascular smooth muscle were created and stacked into a tubular form, forming a vascular graft. Grafts can be sized to meet the range of human coronary artery dimensions by simply changing the 3D-printed guide size.

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