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Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical Studies
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Engineering
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JoVE Journal Engineering
Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical Studies

Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical Studies

DOI:
10.3791/61021-v

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08:33 min

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April 12, 2022

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, , , , , , , , ,
1PMI R&D,Philip Morris Products S.A., 2PMI R&D,Philip Morris Research Laboratories Pte. Ltd., 3Applied Mathematics,University of Twente

Chapters

  • 00:04Introduction
  • 01:08CAG System Assembly
  • 03:14Calculation of CAG Aerosol Concentration and Dilution
  • 04:12CAG Aerosol Generation
  • 05:28Determination of Aerosol Collected Mass (ACM)
  • 06:32Results: Reproducibility and Particle Size Distribution of CAG Generated Aerosols
  • 07:49Conclusion

Summary

Automatic Translation

Automatic Translation

The protocol describes the settings and use of a capillary aerosol generator for continuous production of controlled aerosol from a multispecies liquid solution, suitable for steady large-volume aerosol delivery (e.g., in vivo inhalation studies).

Tags

Keywords: Capillary Aerosol GeneratorCAGAerosol GenerationInhalation ToxicologyElectronic CigaretteLiquid CompositionTemperature ControlAir FlowNucleationCondensationProtocolAssemblyHeating ElementsThermocouplePush-in FittingsO-ringsPeak AdapterCouplingPeristaltic PumpCompressed Air

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