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Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration
JoVE Journal
Medicine
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JoVE Journal Medicine
Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration
DOI:

07:59 min

April 04, 2022

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Chapters

  • 00:00Introduction
  • 00:47Preparation of the Acetylcholine Stock Solution and Syringes
  • 01:35Diagnostic Coronary Angiography
  • 02:05Preparations for Doppler Flow Assessment
  • 02:53Intracoronary Administration of Acetylcholine
  • 04:36Rechallenge
  • 05:39Results: The Acetylcholine-Test and Nitroglycerine Rechallenge
  • 07:38Conclusion

Summary

Automatic Translation

This protocol presents the acetylcholine rechallenge after nitroglycerine as an add-on procedure to spasm provocation testing. The purpose of this technique is to unmask co-existing microvascular spasm in patients with epicardial spasm and to assess the protective efficacy of nitroglycerine on a per-patient level to guide medical therapy.

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