Journal
/
Medicine
/
Induction of Myocardial Infarction and Myocardial Ischemia-Reperfusion Injury in Mice
JoVE Journal
Medicine
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Medicine
Induction of Myocardial Infarction and Myocardial Ischemia-Reperfusion Injury in Mice

Induction of Myocardial Infarction and Myocardial Ischemia-Reperfusion Injury in Mice

DOI:
10.3791/63257-v

•

08:28 min

•

January 19, 2022

•

, , , , , , , , ,
1Department of Cardiology, Union Hospital, Tongji Medical College,Huazhong University of Science and Technology

Chapters

  • 00:04Introduction
  • 00:35Preoperative Preparation
  • 03:10Thoracotomy
  • 04:36LAD Ligation
  • 06:05Reperfusion
  • 07:13Results: A Simple and Reproductive Murine Model for Myocardial Ischemia-Reperfusion Injury and Myocardial Infarction
  • 07:48Conclusion

Summary

Automatic Translation

Automatic Translation

Here we describe a simple and reproducible method that can induce myocardial infarction or myocardial ischemia-reperfusion injury in mice by precision ligation of the left anterior descending coronary artery through micromanipulation.

Tags

Myocardial InfarctionMyocardial Ischemia-reperfusion InjuryMouse ModelLeft Anterior Descending Coronary Artery LigationSurgical ProcedureIntubationMechanical VentilationECG Monitoring

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

Acute Myocardial Infarction in Rats

Induction of Myocardial Infarction in Adult Zebrafish Using Cryoinjury

Ischemia-reperfusion Model of Acute Kidney Injury and Post Injury Fibrosis in Mice

MRI and PET in Mouse Models of Myocardial Infarction

Myocardial Infarction and Functional Outcome Assessment in Pigs

A Murine Model of Myocardial Ischemia-reperfusion Injury through Ligation of the Left Anterior Descending Artery

Minimal Invasive Surgical Procedure of Inducing Myocardial Infarction in Mice

Induction and Assessment of Ischemia-reperfusion Injury in Langendorff-perfused Rat Hearts

Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration

Confirmation of Myocardial Ischemia and Reperfusion Injury in Mice Using Surface Pad Electrocardiography

Read Article