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Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications
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Bioengineering
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JoVE Journal Bioengineering
Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications

Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications

DOI:
10.3791/63867-v

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10:18 min

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May 17, 2022

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, ,
1Department of Bioengineering, School of Engineering and Applied Sciences,University of Pennsylvania, 2BioFrontiers Institute,University of Colorado Boulder, 3Department of Chemical and Biological Engineering, College of Engineering and Applied Science,University of Colorado Boulder

Chapters

  • 00:04Introduction
  • 00:33Fabricating Bulk Hydrogels Inside of a Syringe Using Photocrosslinking
  • 02:35Fabricating Microgels Using Extrusion Fragmentation
  • 05:37Imaging Fragmented Microgels in Suspension Using Epifluorescent Microscope
  • 06:15Assembling Fragmented Microgels into Granular Hydrogels
  • 07:56Extrusion Printing with Fragmented Granular Hydrogels Inks
  • 08:36Results: Characterizing Fragmented Microgel Particles Using ImageJ
  • 09:31Conclusion

Summary

Automatic Translation

Automatic Translation

This work describes straightforward, adaptable, and low-cost methods to fabricate microgels with extrusion fragmentation, process the microgels into injectable granular hydrogels, and apply the granular hydrogels as extrusion printing inks for biomedical applications.

Tags

Granular HydrogelsBiomaterialsHydrogel PrecursorPhoto-crosslinkingUV CuringExtrusionSyringeBiomedical Applications

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