Journal
/
/
Intra-Peritoneal Transplantation for Generating Acute Myeloid Leukemia in Mice
JoVE Journal
Cancer Research
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Cancer Research
Intra-Peritoneal Transplantation for Generating Acute Myeloid Leukemia in Mice
DOI:

10:02 min

January 06, 2023

, , , ,

Chapters

  • 00:05Introduction
  • 00:50Lentiviral Transduction
  • 04:18Serial Transplantation
  • 07:22Results: Comparing Transplantation Efficiency of Murine AML Cells Using Retro-Orbital and Intra-Peritoneal Routes of Transplantation
  • 09:29Conclusion

Summary

Automatic Translation

Here, intra-peritoneal injection of leukemia cells is utilized to establish and propagate acute myeloid leukemia (AML) in mice. This new method is effective in the serial transplantation of AML cells and can serve as an alternative for those who may experience difficulties and inconsistencies with intravenous injection in mice.

Related Videos

Read Article