Formulation and Characterization of Bioactive Agent Containing Nanodisks

Name: Formulation and Characterization of Bioactive Agent Containing Nanodisks
Uploaded: 2023-03-17T14:15:00+00:00
Duration: 7 min 58 s
Description: The term nanodisk refers to a discrete type of nanoparticle comprised of a bilayer forming lipid, a scaffold protein, and an integrated bioactive agent. ...

Kyle Lethcoe; Colin A. Fox; Isabel Moh; Matthew Swackhamer; Michael Karo; Ryan Lockhart; Robert O. Ryan

doi:10.3791/65145

Journal

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Biochemistry

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Formulation and Characterization of Bioactive Agent Containing Nanodisks

JoVE Journal
Biochemistry

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JoVE Journal Biochemistry

Formulation and Characterization of Bioactive Agent Containing Nanodisks

DOI:

10.3791/65145-v

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07:58 min

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March 17, 2023

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Kyle Lethcoe, Colin A. Fox, Isabel Moh, Matthew Swackhamer, Michael Karo, Ryan Lockhart, Robert O. Ryan

¹Department of Biochemistry and Molecular Biology,University of Nevada

Chapters

00:05Introduction
00:54Formulation of Bioactive Agent Containing Nanodisks
03:13Spectral Analysis of AmpB‐Nanodisk Samples
05:56Results: Characterization of Bioactive Agent Containing Nanodisks
07:16Conclusion

Summary

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Here, we describe the production and characterization of bioactive agents containing nanodisks. Amphotericin B nanodisks are taken as an example to describe the protocol in a stepwise manner.

Formulation and Characterization of Bioactive Agent Containing Nanodisks

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