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Journal
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Medicine
/
Automated Processor for Clinical-Scale CAR-T Cell Manufacturing
/
Chimeric Antigen Receptor T Cell Manufacturing on an Automated Cell Processor
JoVE Journal
Medicine
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JoVE Journal
Medicine
Chimeric Antigen Receptor T Cell Manufacturing on an Automated Cell Processor
Chimeric Antigen Receptor T Cell Manufacturing on an Automated Cell Processor
Automated Processor for Clinical-Scale CAR-T Cell Manufacturing
DOI:
10.3791/65488-v
•
01:25 min
•
August 18, 2023
•
Rene Machietto
,
Nicholas Giacobbe
,
Jessica Perazzelli
,
Ted J. Hofmann
,
Allison Barz Leahy
3
,
Stephan A. Grupp
2,3
,
Yongping Wang
3,4
,
Stephan Kadauke
3,4
1
Cell and Gene Therapy Laboratory, Department of Pathology and Laboratory Medicine
,
Children’s Hospital of Philadelphia
,
2
Division of Oncology, Department of Pediatrics
,
Children’s Hospital of Philadelphia
,
3
Perelman School of Medicine at the University of Pennsylvania
,
4
Division of Transfusion Medicine, Department of Pathology and Laboratory Medicine
,
Children’s Hospital of Philadelphia
Tags
CAR-T Cell Manufacturing
Automated Cell Processing
Closed System
Semi-automated
Customizable Protocol
Cost-effective
Cell And Gene Therapy
Immunotherapy
CliniMACS Prodigy
T Cell Transduction
CGMP Compliance
IND Application
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