Aiko Sada International Research Center for Medical Sciences (IRCMS) Kumamoto University Biography Publications Institution JoVE Articles Aiko Sada Aiko Sada is an Associate Professor at the International Research Center for Medical Sciences (IRCMS), Kumamoto University, Japan. She graduated from Shizuoka University with a B.S. degree in 2006, and received her Ph.D. degree from the Graduate University for Advanced Studies (SOKENDAI) in 2011 for her research on RNA binding protein Nanos2 in spermatogonical stem cells under the supervision of Dr. Yumiko Saga (Sada et al., Science 2009, Stem cells 2012). After graduation, she joined Dr. Tudorita Tumbar's lab at Cornell University in Ithaca, NY as a postdoctoral fellow to identify and characterize stem cells and niches in the skin epidermis (Sada et al., Nat. Cell. Biol. 2016, J Invest Dermatol 2017). She is a recipient of a long-term fellowship from the Human Frontier Science Program (HFSP) and a fellowship from the Japan Society for the Promotion of Science (JSPS). In 2016, she returned to Japan after completing her postdoctoral training and started as an Assistant Professor at the Tsukuba Advanced Research Alliance (TARA), University of Tsukuba. In October 2019, she was promoted to Associate Professor and started her own laboratory at Kumamoto University. She was awarded the Ministry of Education, Culture, Sports, Science and Technology (MEXT) Young Scientist Award in 2021 and has been awarded various research grants from Japanese government or private foundations. Her current research focuses on the cellular and molecular mechanisms of skin regeneration and aging, and she is using mouse genetics and three-dimensional skin culture systems to elucidate the regulatory mechanisms of epidermal stem cells under physiological or pathological conditions. Publications Contribution of PDGFRα-positive Cells in Maintenance and Injury Responses in Mouse Large Vessels Scientific Reports. Apr, 2021 | Pubmed ID: 33883668 Vasculature-driven Stem Cell Population Coordinates Tissue Scaling in Dynamic Organs Science Advances. 02, 2021 | Pubmed ID: 33568475 Defining Compartmentalized Stem Cell Populations with Distinct Cell Division Dynamics in the Ocular Surface Epithelium Development (Cambridge, England). 12, 2020 | Pubmed ID: 33199446 Glycome Profiling by Lectin Microarray Reveals Dynamic Glycan Alterations During Epidermal Stem Cell Aging Aging Cell. 08, 2020 | Pubmed ID: 32681764 Wild-type and SAMP8 Mice Show Age-dependent Changes in Distinct Stem Cell Compartments of the Interfollicular Epidermis PloS One. Month, 2019 | Pubmed ID: 31091266 Fibulin-7, a Heparin Binding Matricellular Protein, Promotes Renal Tubular Calcification in Mice Matrix Biology : Journal of the International Society for Matrix Biology. 12, 2018 | Pubmed ID: 29730503 Slc1a3-CreER As a Targeting Tool for the K6+ Epithelial Stem Cell Niche and Its Precursors During Mouse Hair Follicle Cycle The Journal of Investigative Dermatology. 07, 2017 | Pubmed ID: 28259680 Isolatie en kweek van primaire orale keratinocyten uit het volwassen muizengehemelte Yen Xuan Ngo1,2,3, Kenta Haga4, Ayako Suzuki4, Hiroko Kato4, Hiromi Yanagisawa1,5, Kenji Izumi4, Aiko Sada1,3 1Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, 2Ph.D. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, 3International Research Center for Medical Sciences (IRCMS), Kumamoto University, 4Division of Biomimetics, Faculty of Dentistry and Graduate School of Medical and Dental Sciences, Niigata University, 5Faculty of Medicine, University of Tsukuba JoVE 62820 Biology
Isolatie en kweek van primaire orale keratinocyten uit het volwassen muizengehemelte Yen Xuan Ngo1,2,3, Kenta Haga4, Ayako Suzuki4, Hiroko Kato4, Hiromi Yanagisawa1,5, Kenji Izumi4, Aiko Sada1,3 1Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, 2Ph.D. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, 3International Research Center for Medical Sciences (IRCMS), Kumamoto University, 4Division of Biomimetics, Faculty of Dentistry and Graduate School of Medical and Dental Sciences, Niigata University, 5Faculty of Medicine, University of Tsukuba JoVE 62820 Biology