Akira Miyazaki Department of Biochemistry Showa University School of Medicine Biography Publications Institution JoVE Articles Akira Miyazaki has not added a biography. If you are Akira Miyazaki and would like to personalize this page please email our Author Liaison for assistance. Publications Thrombolytic Therapy for Acute Ischemic Stroke: Past and Future Current Pharmaceutical Design. 2019 | Pubmed ID: 30892155 Endothelial Calpain Systems Orchestrate Myofibroblast Differentiation During Wound Healing FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2019 | Pubmed ID: 30199285 Impact of Dysfunctional Protein Catabolism on Macrophage Cholesterol Handling Current Medicinal Chemistry. 2019 | Pubmed ID: 29589525 Expression of Steroidogenic Enzymes and Metabolism of Steroids in COS-7 Cells Known As Non-steroidogenic Cells Scientific Reports. 02, 2018 | Pubmed ID: 29391479 The Impact of Stromal Hic-5 on the Tumorigenesis of Colorectal Cancer Through Lysyl Oxidase Induction and Stromal Remodeling Oncogene. 03, 2018 | Pubmed ID: 29242607 Dysregulation of Calpain Proteolytic Systems Underlies Degenerative Vascular Disorders Journal of Atherosclerosis and Thrombosis. Jan, 2018 | Pubmed ID: 28819082 Emerging Roles of Calpain Proteolytic Systems in Macrophage Cholesterol Handling Cellular and Molecular Life Sciences : CMLS. 08, 2017 | Pubmed ID: 28432377 Differential Lactate and Cholesterol Synthetic Activities in XY and XX Sertoli Cells Scientific Reports. 02, 2017 | Pubmed ID: 28150810 Potential Contribution of the Hepcidin-macrophage Axis to Plaque Vulnerability in Acute Myocardial Infarction in Human International Journal of Cardiology. Jan, 2017 | Pubmed ID: 27855289 Functional Heterogeneity of Nadph Oxidases in Atherosclerotic and Aneurysmal Diseases Journal of Atherosclerosis and Thrombosis. Jan, 2017 | Pubmed ID: 27476665 Priming with Erythropoietin Enhances Cell Survival and Angiogenic Effect of Mesenchymal Stem Cell Implantation in Rat Limb Ischemia Regenerative Therapy. Jun, 2016 | Pubmed ID: 31245482 Calpain-6 Confers Atherogenicity to Macrophages by Dysregulating Pre-mRNA Splicing The Journal of Clinical Investigation. 09, 2016 | Pubmed ID: 27525442 Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Is Involved in Adult Mouse Hippocampal Neurogenesis After Stroke Journal of Molecular Neuroscience : MN. Jun, 2016 | Pubmed ID: 26910758 Fibroblast Growth Factor-23 Induces Cellular Senescence in Human Mesenchymal Stem Cells from Skeletal Muscle Biochemical and Biophysical Research Communications. Feb, 2016 | Pubmed ID: 26797283 Hic-5 Deficiency Attenuates the Activation of Hepatic Stellate Cells and Liver Fibrosis Through Upregulation of Smad7 in Mice Journal of Hepatology. Jan, 2016 | Pubmed ID: 26334580 Hydrogen Peroxide-inducible Clone-5 Regulates Mesangial Cell Proliferation in Proliferative Glomerulonephritis in Mice PloS One. 2015 | Pubmed ID: 25835392 Calpastatin Counteracts Pathological Angiogenesis by Inhibiting Suppressor of Cytokine Signaling 3 Degradation in Vascular Endothelial Cells Circulation Research. Mar, 2015 | Pubmed ID: 25648699 Role of Hic-5 in the Formation of Microvilli-like Structures and the Monocyte-endothelial Interaction That Accelerates Atherosclerosis Cardiovascular Research. Mar, 2015 | Pubmed ID: 25587044 NADPH Oxidase Deficiency Exacerbates Angiotensin II-induced Abdominal Aortic Aneurysms in Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2014 | Pubmed ID: 25189573 Identification of Hic-5 As a Novel Scaffold for the MKK4/p54 JNK Pathway in the Development of Abdominal Aortic Aneurysms Journal of the American Heart Association. May, 2014 | Pubmed ID: 24811612 Time Course-changes in Phosphatidylcholine Profile During Oxidative Modification of Low-density Lipoprotein Lipids in Health and Disease. Mar, 2014 | Pubmed ID: 24625108 Calpain and Atherosclerosis Journal of Atherosclerosis and Thrombosis. 2013 | Pubmed ID: 23171729 Salusin-β Accelerates Inflammatory Responses in Vascular Endothelial Cells Via NF-κB Signaling in LDL Receptor-deficient Mice in Vivo and HUVECs in Vitro American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2012 | Pubmed ID: 22561298 Coexpression of CCR6 and CD146 (MCAM) is a Marker of Effector Memory T-helper 17 Cells The Journal of Dermatology. Oct, 2012 | Pubmed ID: 22486269 Hydrogen Peroxide-inducible Clone 5 (Hic-5) As a Potential Therapeutic Target for Vascular and Other Disorders Journal of Atherosclerosis and Thrombosis. 2012 | Pubmed ID: 22472216 Effects of PKF275-055, a Dipeptidyl Peptidase-4 Inhibitor, on the Development of Atherosclerotic Lesions in Apolipoprotein E-null Mice Metabolism: Clinical and Experimental. Jul, 2012 | Pubmed ID: 22225957 M-Calpain Induction in Vascular Endothelial Cells on Human and Mouse Atheromas and Its Roles in VE-cadherin Disorganization and Atherosclerosis Circulation. Dec, 2011 | Pubmed ID: 22064597 Purification of Recombinant Acyl-coenzyme A:cholesterol Acyltransferase 1 (ACAT1) from H293 Cells and Binding Studies Between the Enzyme and Substrates Using Difference Intrinsic Fluorescence Spectroscopy Biochemistry. Nov, 2010 | Pubmed ID: 20964445 Chronic Infusion of Salusin-alpha and -beta Exerts Opposite Effects on Atherosclerotic Lesion Development in Apolipoprotein E-deficient Mice Atherosclerosis. Sep, 2010 | Pubmed ID: 20684826 Preventive Effects of Heregulin-beta1 on Macrophage Foam Cell Formation and Atherosclerosis Circulation Research. Aug, 2009 | Pubmed ID: 19644050 Increased Plasma Urotensin-II and Carotid Atherosclerosis Are Associated with Vascular Dementia Journal of Atherosclerosis and Thrombosis. Jun, 2009 | Pubmed ID: 19638714 Leptin Modulates ACAT1 Expression and Cholesterol Efflux from Human Macrophages American Journal of Physiology. Endocrinology and Metabolism. Aug, 2009 | Pubmed ID: 19625677 Human Urotensin II Promotes Hypertension and Atherosclerotic Cardiovascular Diseases Current Medicinal Chemistry. 2009 | Pubmed ID: 19199921 Angiotensin II Upregulates Acyl-CoA:cholesterol Acyltransferase-1 Via the Angiotensin II Type 1 Receptor in Human Monocyte-macrophages Hypertension Research : Official Journal of the Japanese Society of Hypertension. Sep, 2008 | Pubmed ID: 18971559 Chronic Urotensin II Infusion Enhances Macrophage Foam Cell Formation and Atherosclerosis in Apolipoprotein E-knockout Mice Journal of Hypertension. Oct, 2008 | Pubmed ID: 18806619 Serum Salusin-alpha Levels Are Decreased and Correlated Negatively with Carotid Atherosclerosis in Essential Hypertensive Patients Hypertension Research : Official Journal of the Japanese Society of Hypertension. Mar, 2008 | Pubmed ID: 18497465 Increased Plasma Urotensin-II Levels Are Associated with Diabetic Retinopathy and Carotid Atherosclerosis in Type 2 Diabetes Clinical Science (London, England : 1979). Dec, 2008 | Pubmed ID: 18338983 Impact of Salusin-alpha and -beta on Human Macrophage Foam Cell Formation and Coronary Atherosclerosis Circulation. Feb, 2008 | Pubmed ID: 18212280 Use of Serum Insulin-like Growth Factor-I Levels to Predict Psychiatric Non-response to Donepezil in Patients with Alzheimer's Disease Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Feb, 2008 | Pubmed ID: 17714966 Increased Human Urotensin II Levels Are Correlated with Carotid Atherosclerosis in Essential Hypertension American Journal of Hypertension. Feb, 2007 | Pubmed ID: 17261470 Impact of Increased Plasma Serotonin Levels and Carotid Atherosclerosis on Vascular Dementia Atherosclerosis. Nov, 2007 | Pubmed ID: 17049533 Human Urotensin-II Potentiates the Mitogenic Effect of Mildly Oxidized Low-density Lipoprotein on Vascular Smooth Muscle Cells: Comparison with Other Vasoactive Agents and Hydrogen Peroxide Hypertension Research : Official Journal of the Japanese Society of Hypertension. Oct, 2006 | Pubmed ID: 17283870 Human Urotensin II As a Link Between Hypertension and Coronary Artery Disease Hypertension Research : Official Journal of the Japanese Society of Hypertension. Jun, 2006 | Pubmed ID: 16940699 Ndrg4 Enhances NGF-induced ERK Activation Uncoupled with Elk-1 Activation Journal of Cellular Biochemistry. May, 2006 | Pubmed ID: 16408304 Serotonin Acts As an Up-regulator of Acyl-coenzyme A:cholesterol Acyltransferase-1 in Human Monocyte-macrophages Atherosclerosis. Jun, 2006 | Pubmed ID: 16157345 Inhibitors of Acyl-coenzyme A: Cholesterol Acyltransferase Current Drug Targets. Cardiovascular & Haematological Disorders. Dec, 2005 | Pubmed ID: 16503866 Relationship Between Serum Insulin-like Growth Factor-1 Levels and Alzheimer's Disease and Vascular Dementia Journal of the American Geriatrics Society. Oct, 2005 | Pubmed ID: 16181175 Human Urotensin II Accelerates Foam Cell Formation in Human Monocyte-derived Macrophages Hypertension (Dallas, Tex. : 1979). Oct, 2005 | Pubmed ID: 16172428 High Prevalence of Chlamydia Pneumoniae Antibodies and Increased High-sensitive C-reactive Protein in Patients with Vascular Dementia Journal of the American Geriatrics Society. Apr, 2005 | Pubmed ID: 15817002 [Acyl-coenzyme A: Cholesterol Acyltransferase (ACAT)] Nihon Rinsho. Japanese Journal of Clinical Medicine. Dec, 2004 | Pubmed ID: 15658270 Genomic Organization, Expression, and Comparative Analysis of Noncoding Region of the Rat Ndrg4 Gene Gene. Jan, 2004 | Pubmed ID: 14693380 Acyl-coenzyme A:cholesterol Acyltransferase Inhibitors for Controlling Hypercholesterolemia and Atherosclerosis Current Opinion in Investigational Drugs (London, England : 2000). Sep, 2003 | Pubmed ID: 14582454 Advanced Glycation End Products (AGE) Inhibit Scavenger Receptor Class B Type I-mediated Reverse Cholesterol Transport: a New Crossroad of AGE to Cholesterol Metabolism Journal of Atherosclerosis and Thrombosis. 2003 | Pubmed ID: 12621157 एक पर झिल्ली पाचन तकनीक का उपयोग कर प्रोटीन-प्रोटीन इंटरेक्शन का मूल्यांकन Takashi Obama*1, Takuro Miyazaki*2, Toshihiro Aiuchi1, Akira Miyazaki2, Hiroyuki Itabe1 1Division of Biological Chemistry, Department of Molecular Biology, Showa University School of Pharmacy, 2Department of Biochemistry, Showa University School of Medicine JoVE 59733 Biochemistry
एक पर झिल्ली पाचन तकनीक का उपयोग कर प्रोटीन-प्रोटीन इंटरेक्शन का मूल्यांकन Takashi Obama*1, Takuro Miyazaki*2, Toshihiro Aiuchi1, Akira Miyazaki2, Hiroyuki Itabe1 1Division of Biological Chemistry, Department of Molecular Biology, Showa University School of Pharmacy, 2Department of Biochemistry, Showa University School of Medicine JoVE 59733 Biochemistry