Alan J. Davidson Department of Molecular Medicine and Pathology, School of Medical Sciences University of Auckland Biography Publications Institution JoVE Articles Alan J. Davidson has not added a biography. If you are Alan J. Davidson and would like to personalize this page please email our Author Liaison for assistance. Publications The Dynamics of Metabolic Characterization in IPSC-Derived Kidney Organoid Differentiation a Comparative Omics Approach Frontiers in Genetics. 2021 | Pubmed ID: 33643392 Human Urinal Cell Reprogramming: Synthetic 3D Peptide Hydrogels Enhance Induced Pluripotent Stem Cell Population Homogeneity ACS Biomaterials Science & Engineering. 11, 2020 | Pubmed ID: 33449655 Protocol for Large-Scale Production of Kidney Organoids from Human Pluripotent Stem Cells STAR Protocols. Dec, 2020 | Pubmed ID: 33377044 SOX9 Promotes Stress-responsive Transcription of VGF Nerve Growth Factor Inducible Gene in Renal Tubular Epithelial Cells The Journal of Biological Chemistry. 11, 2020 | Pubmed ID: 32887795 ADAM10 Mediates Ectopic Proximal Tubule Development and Renal Fibrosis Through Notch Signalling The Journal of Pathology. 11, 2020 | Pubmed ID: 32715474 Common Variants Coregulate Expression of GBA and Modifier Genes to Delay Parkinson's Disease Onset Movement Disorders : Official Journal of the Movement Disorder Society. 08, 2020 | Pubmed ID: 32557794 The Utility of Human Kidney Organoids in Modeling Kidney Disease Seminars in Nephrology. 03, 2020 | Pubmed ID: 32303281 Use of Human Induced Pluripotent Stem Cells and Kidney Organoids To Develop a Cysteamine/mTOR Inhibition Combination Therapy for Cystinosis Journal of the American Society of Nephrology : JASN. 05, 2020 | Pubmed ID: 32198276 Evaluation of Cisplatin-induced Injury in Human Kidney Organoids American Journal of Physiology. Renal Physiology. 04, 2020 | Pubmed ID: 32150447 Transcriptional Profiling of the Zebrafish Proximal Tubule American Journal of Physiology. Renal Physiology. 08, 2019 | Pubmed ID: 31188030 Mind the Gap: Renal Tubule Responses to Injury and the Role of Cxcl12 and Myc Annals of Translational Medicine. Mar, 2019 | Pubmed ID: 31032310 Enhancing Regeneration After Acute Kidney Injury by Promoting Cellular Dedifferentiation in Zebrafish Disease Models & Mechanisms. 04, 2019 | Pubmed ID: 30890583 Turning Mesoderm into Kidney Seminars in Cell & Developmental Biology. 07, 2019 | Pubmed ID: 30172050 The Role of Macrophages During Acute Kidney Injury: Destruction and Repair Pediatric Nephrology (Berlin, Germany). 04, 2019 | Pubmed ID: 29383444 A Novel Mechanism of Gland Formation in Zebrafish Involving Transdifferentiation of Renal Epithelial Cells and Live Cell Extrusion ELife. 11, 2018 | Pubmed ID: 30394875 A Simple Bioreactor-Based Method to Generate Kidney Organoids From Pluripotent Stem Cells Stem Cell Reports. 08, 2018 | Pubmed ID: 30033089 Transgenic Xenopus Laevis Line for In Vivo Labeling of Nephrons Within the Kidney Genes. Apr, 2018 | Pubmed ID: 29642376 The Zebrafish Kidney Mutant Zeppelin Reveals That Brca2/fancd1 is Essential for Pronephros Development Developmental Biology. Aug, 2017 | Pubmed ID: 28579318 Zebrafish Pronephros Development Results and Problems in Cell Differentiation. 2017 | Pubmed ID: 28409341 Wnt8a Expands the Pool of Embryonic Kidney Progenitors in Zebrafish Developmental Biology. 05, 2017 | Pubmed ID: 28359809 The Vital Dye CDr10b Labels the Zebrafish Mid-Intestine and Lumen Molecules (Basel, Switzerland). Mar, 2017 | Pubmed ID: 28335401 Pronephric Tubule Formation in Zebrafish: Morphogenesis and Migration Pediatric Nephrology (Berlin, Germany). 02, 2017 | Pubmed ID: 26942753 Derivation of Corneal Keratocyte-Like Cells from Human Induced Pluripotent Stem Cells PloS One. 2016 | Pubmed ID: 27792791 Caudal Migration and Proliferation of Renal Progenitors Regulates Early Nephron Segment Size in Zebrafish Scientific Reports. 10, 2016 | Pubmed ID: 27759103 BMP and Retinoic Acid Regulate Anterior-posterior Patterning of the Non-axial Mesoderm Across the Dorsal-ventral Axis Nature Communications. 07, 2016 | Pubmed ID: 27406002 The Small Molecule Probe PT-Yellow Labels the Renal Proximal Tubules in Zebrafish Chemical Communications (Cambridge, England). 2015 | Pubmed ID: 25407666 Kidney Injury and Regeneration in Zebrafish Seminars in Nephrology. Jul, 2014 | Pubmed ID: 25217272 Kidney Regeneration in Fish Nephron. Experimental Nephrology. 2014 | Pubmed ID: 24854639 Hnf1beta and Nephron Segmentation Pediatric Nephrology (Berlin, Germany). Apr, 2014 | Pubmed ID: 24190171 Kidney Regeneration: Common Themes from the Embryo to the Adult Pediatric Nephrology (Berlin, Germany). Apr, 2014 | Pubmed ID: 24005792 A Cdx4-Sall4 Regulatory Module Controls the Transition from Mesoderm Formation to Embryonic Hematopoiesis Stem Cell Reports. 2013 | Pubmed ID: 24286030 Histone Deacetylase Inhibitor Enhances Recovery After AKI Journal of the American Society of Nephrology : JASN. May, 2013 | Pubmed ID: 23620402 A Zebrafish Model of Conditional Targeted Podocyte Ablation and Regeneration Kidney International. Jun, 2013 | Pubmed ID: 23466998 HNF1β is Essential for Nephron Segmentation During Nephrogenesis Journal of the American Society of Nephrology : JASN. Jan, 2013 | Pubmed ID: 23160512 Wt1a, Foxc1a, and the Notch Mediator Rbpj Physically Interact and Regulate the Formation of Podocytes in Zebrafish Developmental Biology. Oct, 2011 | Pubmed ID: 21871448 Zebrafish Nephrogenesis Involves Dynamic Spatiotemporal Expression Changes in Renal Progenitors and Essential Signals from Retinoic Acid and Irx3b Developmental Dynamics : an Official Publication of the American Association of Anatomists. Aug, 2011 | Pubmed ID: 21761484 Zebrafish Kidney Development: Basic Science to Translational Research Birth Defects Research. Part C, Embryo Today : Reviews. Jun, 2011 | Pubmed ID: 21671354 Interactions Between Cdx Genes and Retinoic Acid Modulate Early Cardiogenesis Developmental Biology. Jun, 2011 | Pubmed ID: 21466798 Uncharted Waters: Nephrogenesis and Renal Regeneration in Fish and Mammals Pediatric Nephrology (Berlin, Germany). Sep, 2011 | Pubmed ID: 21336813 Identification of Adult Nephron Progenitors Capable of Kidney Regeneration in Zebrafish Nature. Feb, 2011 | Pubmed ID: 21270795 Zebrafish Wnt9a is Expressed in Pharyngeal Ectoderm and is Required for Palate and Lower Jaw Development Mechanisms of Development. Jan-Feb, 2011 | Pubmed ID: 21093584 Zebrafish Kidney Development Methods in Cell Biology. 2010 | Pubmed ID: 21111220 Interaction of Retinoic Acid and Scl Controls Primitive Blood Development Blood. Jul, 2010 | Pubmed ID: 20410509 The Role and Regulation of Friend of GATA-1 (FOG-1) During Blood Development in the Zebrafish Blood. Nov, 2009 | Pubmed ID: 19729519 Pseudomonas Aeruginosa Infection of Zebrafish Involves Both Host and Pathogen Determinants Infection and Immunity. Apr, 2009 | Pubmed ID: 19168742 Intestinal Differentiation in Zebrafish Requires Cdx1b, a Functional Equivalent of Mammalian Cdx2 Gastroenterology. Nov, 2008 | Pubmed ID: 18804112 Montalcino, A Zebrafish Model for Variegate Porphyria Experimental Hematology. Sep, 2008 | Pubmed ID: 18550261 BMP and Wnt Specify Hematopoietic Fate by Activation of the Cdx-Hox Pathway Cell Stem Cell. Jan, 2008 | Pubmed ID: 18371423 The Cdx Genes and Retinoic Acid Control the Positioning and Segmentation of the Zebrafish Pronephros PLoS Genetics. Oct, 2007 | Pubmed ID: 17953490 Cdx4 Dysregulates Hox Gene Expression and Generates Acute Myeloid Leukemia Alone and in Cooperation with Meis1a in a Murine Model Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006 | Pubmed ID: 17068127 Sustained Bmp Signaling is Essential for Cloaca Development in Zebrafish Development (Cambridge, England). Jun, 2006 | Pubmed ID: 16672335 The Caudal-related Homeobox Genes Cdx1a and Cdx4 Act Redundantly to Regulate Hox Gene Expression and the Formation of Putative Hematopoietic Stem Cells During Zebrafish Embryogenesis Developmental Biology. Apr, 2006 | Pubmed ID: 16457800 Deficiency of Glutaredoxin 5 Reveals Fe-S Clusters Are Required for Vertebrate Haem Synthesis Nature. Aug, 2005 | Pubmed ID: 16110529 Regulation of the Lmo2 Promoter During Hematopoietic and Vascular Development in Zebrafish Developmental Biology. May, 2005 | Pubmed ID: 15893977 Zebrafish Scl Functions Independently in Hematopoietic and Endothelial Development Developmental Biology. Jan, 2005 | Pubmed ID: 15617691 The Chianti Zebrafish Mutant Provides a Model for Erythroid-specific Disruption of Transferrin Receptor 1 Development (Cambridge, England). Dec, 2004 | Pubmed ID: 15563524 An Mll-dependent Hox Program Drives Hematopoietic Progenitor Expansion Current Biology : CB. Nov, 2004 | Pubmed ID: 15556871 The 'definitive' (and 'primitive') Guide to Zebrafish Hematopoiesis Oncogene. Sep, 2004 | Pubmed ID: 15378083 Expression and Mapping of Duplicate Neuropilin-1 and Neuropilin-2 Genes in Developing Zebrafish Gene Expression Patterns : GEP. Jul, 2004 | Pubmed ID: 15183302 Cdx4 Mutants Fail to Specify Blood Progenitors and Can Be Rescued by Multiple Hox Genes Nature. Sep, 2003 | Pubmed ID: 13679919 Inhibition of Zebrafish Epidermal Growth Factor Receptor Activity Results in Cardiovascular Defects Mechanisms of Development. Jul, 2003 | Pubmed ID: 12915231 Cell-specific Mitotic Defect and Dyserythropoiesis Associated with Erythroid Band 3 Deficiency Nature Genetics. May, 2003 | Pubmed ID: 12669066 Biomedicine. Love, Honor, and Protect (your Liver) Science (New York, N.Y.). Feb, 2003 | Pubmed ID: 12574609 Radar is Required for the Establishment of Vascular Integrity in the Zebrafish Developmental Biology. Nov, 2002 | Pubmed ID: 12413901 Neuropilin-1 is Required for Vascular Development and is a Mediator of VEGF-dependent Angiogenesis in Zebrafish Proceedings of the National Academy of Sciences of the United States of America. Aug, 2002 | Pubmed ID: 12142468 A Simplified Method for Generating Kidney Organoids from Human Pluripotent Stem Cells Aneta Przepiorski1, Amanda E. Crunk1, Teresa M. Holm2, Veronika Sander2, Alan J. Davidson2, Neil A. Hukriede1,3 1Department of Developmental Biology, University of Pittsburgh, School of Medicine, 2Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, 3Center for Critical Care Nephrology, University of Pittsburgh, School of Medicine JoVE 62452 Developmental Biology Transplantation of Cells Directly into the Kidney of Adult Zebrafish Cuong Q. Diep1, Alan J. Davidson1 1Center for Regenerative Medicine, Massachusetts General Hospital JoVE 2725 Biology
A Simplified Method for Generating Kidney Organoids from Human Pluripotent Stem Cells Aneta Przepiorski1, Amanda E. Crunk1, Teresa M. Holm2, Veronika Sander2, Alan J. Davidson2, Neil A. Hukriede1,3 1Department of Developmental Biology, University of Pittsburgh, School of Medicine, 2Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, 3Center for Critical Care Nephrology, University of Pittsburgh, School of Medicine JoVE 62452 Developmental Biology
Transplantation of Cells Directly into the Kidney of Adult Zebrafish Cuong Q. Diep1, Alan J. Davidson1 1Center for Regenerative Medicine, Massachusetts General Hospital JoVE 2725 Biology