Alessandro Quattrone Laboratory of Translational Genomics, Centre for Integrative Biology University of Trento Biography Publications Institution JoVE Articles Alessandro Quattrone has not added a biography. If you are Alessandro Quattrone and would like to personalize this page please email our Author Liaison for assistance. Publications Three Distinct Ribosome Assemblies Modulated by Translation Are the Building Blocks of Polysomes The Journal of Cell Biology. Feb, 2015 | Pubmed ID: 25713412 Translational Downregulation of HSP90 Expression by Iron Chelators in Neuroblastoma Cells Molecular Pharmacology. Mar, 2015 | Pubmed ID: 25564462 Fingerprints of a Message: Integrating Positional Information on the Transcriptome Frontiers in Cell and Developmental Biology. 2014 | Pubmed ID: 25364746 Lineage-specific Interface Proteins Match Up the Cell Cycle and Differentiation in Embryo Stem Cells Stem Cell Research. Sep, 2014 | Pubmed ID: 25173649 Telomerase Activated Thymidine Analogue Pro-drug is a New Molecule Targeting Hepatocellular Carcinoma Journal of Hepatology. Nov, 2014 | Pubmed ID: 24862448 PTRcombiner: Mining Combinatorial Regulation of Gene Expression from Post-transcriptional Interaction Maps BMC Genomics. 2014 | Pubmed ID: 24758252 Enhanced Microbial Diversity in the Saliva Microbiome Induced by Short-term Probiotic Intake Revealed by 16S RRNA Sequencing on the IonTorrent PGM Platform Journal of Biotechnology. Nov, 2014 | Pubmed ID: 24670254 Genipin-crosslinked Gelatin-silk Fibroin Hydrogels for Modulating the Behaviour of Pluripotent Cells Journal of Tissue Engineering and Regenerative Medicine. Jan, 2014 | Pubmed ID: 24668649 Increased Frequency of Minimal Homozygous Deletions is Associated with Poor Prognosis in Primary Malignant Melanoma Patients Genes, Chromosomes & Cancer. Jun, 2014 | Pubmed ID: 24615732 A Cell-based High-throughput Screen Addressing 3'UTR-dependent Regulation of the MYCN Gene Molecular Biotechnology. Jul, 2014 | Pubmed ID: 24515800 Loss of Protein Kinase Cδ/HuR Interaction is Necessary to Doxorubicin Resistance in Breast Cancer Cell Lines The Journal of Pharmacology and Experimental Therapeutics. Apr, 2014 | Pubmed ID: 24492650 TRanslatome: an R/Bioconductor Package to Portray Translational Control Bioinformatics (Oxford, England). Jan, 2014 | Pubmed ID: 24222209 A Novel Mutation in the Upstream Open Reading Frame of the CDKN1B Gene Causes a MEN4 Phenotype PLoS Genetics. Mar, 2013 | Pubmed ID: 23555276 MRNA Fate: Life and Death of the MRNA in the Cytoplasm RNA Biology. Mar, 2013 | Pubmed ID: 23466755 Hyper Conserved Elements in Vertebrate MRNA 3'-UTRs Reveal a Translational Network of RNA-binding Proteins Controlled by HuR Nucleic Acids Research. Mar, 2013 | Pubmed ID: 23376935 Synergistic Effect of L-Carnosine and EGCG in the Prevention of Physiological Brain Aging Current Pharmaceutical Design. 2013 | Pubmed ID: 23092324 Tuning the Engine: an Introduction to Resources on Post-transcriptional Regulation of Gene Expression RNA Biology. Oct, 2012 | Pubmed ID: 22995832 Widespread Uncoupling Between Transcriptome and Translatome Variations After a Stimulus in Mammalian Cells BMC Genomics. 2012 | Pubmed ID: 22672192 Downregulation of HuR As a New Mechanism of Doxorubicin Resistance in Breast Cancer Cells Molecular Cancer. 2012 | Pubmed ID: 22436134 Segmental Chromosome Aberrations Converge on Overexpression of Mitotic Spindle Regulatory Genes in High-risk Neuroblastoma Genes, Chromosomes & Cancer. Jun, 2012 | Pubmed ID: 22337647 The Role of MiR-103 and MiR-107 in Regulation of CDK5R1 Expression and in Cellular Migration PloS One. 2011 | Pubmed ID: 21625387 Acycloguanosyl 5'-thymidyltriphosphate, a Thymidine Analogue Prodrug Activated by Telomerase, Reduces Pancreatic Tumor Growth in Mice Gastroenterology. Feb, 2011 | Pubmed ID: 21044629 Functional Analysis of CDKN2A/p16INK4a 5'-UTR Variants Predisposing to Melanoma Human Molecular Genetics. Apr, 2010 | Pubmed ID: 20093296 NELAV Proteins Alteration in Alzheimer's Disease Brain: a Novel Putative Target for Amyloid-beta Reverberating on AbetaPP Processing Journal of Alzheimer's Disease : JAD. 2009 | Pubmed ID: 19221430 Different Involvement of Type 1, 2, and 3 Ryanodine Receptors in Memory Processes Learning & Memory (Cold Spring Harbor, N.Y.). May, 2008 | Pubmed ID: 18441289 Post-transcriptional Regulation of Neuro-oncological Ventral Antigen 1 by the Neuronal RNA-binding Proteins ELAV The Journal of Biological Chemistry. Mar, 2008 | Pubmed ID: 18218628 Metabolomics: Available Results, Current Research Projects in Breast Cancer, and Future Applications Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jul, 2007 | Pubmed ID: 17502626 Novel Mutations of Dystrophin Gene in DMD Patients Detected by Rapid Scanning in Biplex Exons DHPLC Analysis Biomolecular Engineering. Jun, 2007 | Pubmed ID: 17145200 Identification of Two Novel Mutations and of a Novel Critical Region in the KRIT1 Gene Neurogenetics. Jan, 2007 | Pubmed ID: 17043900 Monomorphism of Human Cytochrome C Genomics. Nov, 2006 | Pubmed ID: 16934433 Curcumin Activates Defensive Genes and Protects Neurons Against Oxidative Stress Antioxidants & Redox Signaling. Mar-Apr, 2006 | Pubmed ID: 16677086 A Role for the ELAV RNA-binding Proteins in Neural Stem Cells: Stabilization of Msi1 MRNA Journal of Cell Science. Apr, 2006 | Pubmed ID: 16554442 Global Alterations in MRNA Polysomal Recruitment in a Cell Model of Colorectal Cancer Progression to Metastasis Carcinogenesis. Jul, 2006 | Pubmed ID: 16531451 Principal Component Analysis of the Conformational Freedom Within the EF-hand Superfamily Journal of Proteome Research. Nov-Dec, 2005 | Pubmed ID: 16335940 Neuronal ELAV Proteins Enhance MRNA Stability by a PKCalpha-dependent Pathway Proceedings of the National Academy of Sciences of the United States of America. Aug, 2005 | Pubmed ID: 16099831 Antiproliferative Activity of Melatonin by Transcriptional Inhibition of Cyclin D1 Expression: a Molecular Basis for Melatonin-induced Oncostatic Effects Journal of Pineal Research. Aug, 2005 | Pubmed ID: 15978052 A Prokaryotic Superoxide Dismutase Paralog Lacking Two Cu Ligands: from Largely Unstructured in Solution to Ordered in the Crystal Proceedings of the National Academy of Sciences of the United States of America. May, 2005 | Pubmed ID: 15897454 The Common -866G/A Polymorphism in the Promoter Region of the UCP-2 Gene is Associated with Reduced Risk of Type 2 Diabetes in Caucasians from Italy The Journal of Clinical Endocrinology and Metabolism. Feb, 2005 | Pubmed ID: 15562023 Solution Structure of Human Beta-parvalbumin and Structural Comparison with Its Paralog Alpha-parvalbumin and with Their Rat Orthologs Biochemistry. Dec, 2004 | Pubmed ID: 15610002 Paramagnetism-based Refinement Strategy for the Solution Structure of Human Alpha-parvalbumin Biochemistry. May, 2004 | Pubmed ID: 15122922 Association Between the HOXA1 A218G Polymorphism and Increased Head Circumference in Patients with Autism Biological Psychiatry. Feb, 2004 | Pubmed ID: 14960295 Increase of the RNA-binding Protein HuD and Posttranscriptional Up-regulation of the GAP-43 Gene During Spatial Memory Proceedings of the National Academy of Sciences of the United States of America. Feb, 2004 | Pubmed ID: 14745023 Calcium-regulated GTPase Activity in the Calcium-binding Protein Calexcitin Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. Aug, 2003 | Pubmed ID: 12892754 Antisense Knockdown of the Shaker-like Kv1.1 Gene Abolishes the Central Stimulatory Effects of Amphetamines in Mice and Rats Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Jun, 2003 | Pubmed ID: 12700677 High-throughput Screening for Chemical Modulators of Post-transcriptionally Regulated Genes Viktoryia Sidarovich1, Valentina Adami2, Alessandro Quattrone1 1Laboratory of Translational Genomics, Centre for Integrative Biology, University of Trento, 2High Throughput Screening Core Facility, Centre for Integrative Biology, University of Trento JoVE 52568 Biology
High-throughput Screening for Chemical Modulators of Post-transcriptionally Regulated Genes Viktoryia Sidarovich1, Valentina Adami2, Alessandro Quattrone1 1Laboratory of Translational Genomics, Centre for Integrative Biology, University of Trento, 2High Throughput Screening Core Facility, Centre for Integrative Biology, University of Trento JoVE 52568 Biology