Alexandros Spyridonidis Institute of Cell Therapy, Bone Marrow Transplantation Lab, Department of Medicine University of Patras Biography Publications Institution JoVE Articles Alexandros Spyridonidis has not added a biography. If you are Alexandros Spyridonidis and would like to personalize this page please email our Author Liaison for assistance. Publications Thiotepa-busulfan-fludarabine Compared to Treosulfan-based Conditioning for Haploidentical Transplant With Posttransplant Cyclophosphamide in Patients With Acute Myeloid Leukemia in Remission: A Study From the Acute Leukemia Working Party of the EBMT HemaSphere. Oct, 2023 | Pubmed ID: 37746158 Allogeneic Hematopoietic Cell Transplantation for Patients with AML Aged 70 Years or Older in First Remission. A Study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT) Bone Marrow Transplantation. Sep, 2023 | Pubmed ID: 37386253 Study Protocol: Phase I/II Trial of Induced HLA-G Regulatory T Cells in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation from an HLA-matched Sibling Donor Frontiers in Medicine. 2023 | Pubmed ID: 37275377 Total Body Irradiation Versus Busulfan Based Intermediate Intensity Conditioning for Stem Cell Transplantation in ALL Patients >45 Years-a Registry-based Study by the Acute Leukemia Working Party of the EBMT Bone Marrow Transplantation. Aug, 2023 | Pubmed ID: 37147469 Solid Tumor Transmission from Donor to Recipient After Allogeneic Stem Cell Transplantation: It is Rare but It Happens! Blood Transfusion = Trasfusione Del Sangue. Sep, 2023 | Pubmed ID: 37146299 Empowering the Potential of CAR-T Cell Immunotherapies by Epigenetic Reprogramming Cancers. Mar, 2023 | Pubmed ID: 37046597 Impact of Measurable Residual Disease on Outcomes of Unrelated Donor Haematopoietic Cell Transplantation with Post-transplant Cyclophosphamide in AML in First Complete Remission British Journal of Haematology. Jun, 2023 | Pubmed ID: 36949658 Reduced 8-Gray Compared to Standard 12-Gray Total Body Irradiation for Allogeneic Transplantation in First Remission Acute Lymphoblastic Leukemia: A Study of the Acute Leukemia Working Party of the EBMT HemaSphere. Jan, 2023 | Pubmed ID: 36698616 Is a Third SARS-CoV-2 Vaccine Dose Efficient in Allogeneic Haematopoietic Cell Transplant Recipients? British Journal of Haematology. Apr, 2023 | Pubmed ID: 36477621 To Transplant or Not To Transplant in First Remission Acute Lymphoblastic Leukemia? Study Group Data Give Some Answers, but Not All Transplantation and Cellular Therapy. Dec, 2022 | Pubmed ID: 36470611 Correction To: Impact of Conditioning Regimen Intensity on Outcomes of Second Allogeneic Hematopoietic Cell Transplantation for Secondary Acute Myelogenous Leukemia Bone Marrow Transplantation. Dec, 2022 | Pubmed ID: 36207624 Should Anti-thymocyte Globulin Be Added in Post-transplant Cyclophosphamide Based Matched Unrelated Donor Peripheral Blood Stem Cell Transplantation for Acute Myeloid Leukemia? A Study on Behalf of the Acute Leukemia Working Party of the EBMT Bone Marrow Transplantation. Dec, 2022 | Pubmed ID: 36071114 Impact of Cytogenetic Risk on Outcomes of Non-T-Cell-Depleted Haploidentical Hematopoietic Cell Transplantation in Patients with Relapsed or Refractory Acute Myeloid Leukemia Transplantation and Cellular Therapy. Nov, 2022 | Pubmed ID: 36031079 Impact of Conditioning Regimen Intensity on Outcomes of Second Allogeneic Hematopoietic Cell Transplantation for Secondary Acute Myelogenous Leukemia Bone Marrow Transplantation. Jul, 2022 | Pubmed ID: 35501565 Accurate SARS-CoV-2 Seroprevalence Surveys Require Robust Multi-antigen Assays Scientific Reports. Mar, 2021 | Pubmed ID: 33758278 Remdesivir and Tocilizumab: Mix or Match Journal of Medical Virology. Jan, 2021 | Pubmed ID: 32492200 "Cerberus" T Cells: A Glucocorticoid-Resistant, Multi-Pathogen Specific T Cell Product to Fight Infections in Severely Immunocompromised Patients Frontiers in Immunology. 2020 | Pubmed ID: 33537032 Anti-SARS-CoV-2 Antibody Responses in Convalescent Plasma Donors Are Increased in Hospitalized Patients; Subanalyses of a Phase 2 Clinical Study Microorganisms. Nov, 2020 | Pubmed ID: 33260775 Clinical Practice Recommendation on Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia Patients with -internal Tandem Duplication: a Position Statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation Haematologica. Jun, 2020 | Pubmed ID: 32241850 Correction: Redefining and Measuring Transplant Conditioning Intensity in Current Era: a Study in Acute Myeloid Leukemia Patients Bone Marrow Transplantation. Jun, 2020 | Pubmed ID: 32144364 Management of Patients with Acute Lymphoblastic Leukemia in Routine Clinical Practice: Minimal Residual Disease Testing, Treatment Patterns and Clinical Outcomes in Belgium, Greece and Switzerland Leukemia Research. Apr, 2020 | Pubmed ID: 32135394 Redefining and Measuring Transplant Conditioning Intensity in Current Era: a Study in Acute Myeloid Leukemia Patients Bone Marrow Transplantation. Jun, 2020 | Pubmed ID: 31996792 Ectopic Lck Expression in CLL Demarcates Intratumoral Subpopulations with Aberrant B-cell Receptor Signaling Blood Advances. Apr, 2018 | Pubmed ID: 29669754 Sorafenib Promotes Graft-versus-leukemia Activity in Mice and Humans Through IL-15 Production in FLT3-ITD-mutant Leukemia Cells Nature Medicine. Mar, 2018 | Pubmed ID: 29431743 Plasma and Serum Metabolite Association Networks: Comparability Within and Between Studies Using NMR and MS Profiling Journal of Proteome Research. Jul, 2017 | Pubmed ID: 28517934 How Much Immunosuppression Do We Need? Blood. Mar, 2017 | Pubmed ID: 28280046 Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia Cell Stem Cell. Mar, 2017 | Pubmed ID: 28215825 Simple in Vitro Generation of Human Leukocyte Antigen-G-expressing T-regulatory Cells Through Pharmacological Hypomethylation for Adoptive Cellular Immunotherapy Against Graft-versus-host Disease Cytotherapy. Apr, 2017 | Pubmed ID: 28162915 The β-globin Replicator Greatly Enhances the Potential of S/MAR Based Episomal Vectors for Gene Transfer into Human Haematopoietic Progenitor Cells Scientific Reports. Jan, 2017 | Pubmed ID: 28106085 Lack of LCAT Reduces the LPS-neutralizing Capacity of HDL and Enhances LPS-induced Inflammation in Mice Biochimica Et Biophysica Acta. Oct, 2015 | Pubmed ID: 26170061 DNA Damage and Repair in Epithelium After Allogeneic Hematopoietic Stem Cell Transplantation International Journal of Molecular Sciences. Nov, 2012 | Pubmed ID: 23443095 Outcomes and Prognostic Factors of Adults with Acute Lymphoblastic Leukemia Who Relapse After Allogeneic Hematopoietic Cell Transplantation. An Analysis on Behalf of the Acute Leukemia Working Party of EBMT Leukemia. Jun, 2012 | Pubmed ID: 22290066 DNA Chimerism and Its Consequences After Allogeneic Hematopoietic Cell Transplantation Chimerism. Jan, 2011 | Pubmed ID: 21547035 A GMP-Compliant Procedure for the Generation of Gene-Modified T cells Nikolaos Savvopoulos1, Klearchos Stampolitis1, Georgios Alexandropoulos1, Dionysia Kefala1, Memnon Lysandrou1, Vassiliki Zacharioudaki1, Nikos Tsolakos2, Alexandros Spyridonidis1 1Institute of Cell Therapy, Bone Marrow Transplantation Lab, Department of Medicine, University of Patras, 2Protatonce Ltd, Demokritos Science Park JoVE 65097 Bioengineering
A GMP-Compliant Procedure for the Generation of Gene-Modified T cells Nikolaos Savvopoulos1, Klearchos Stampolitis1, Georgios Alexandropoulos1, Dionysia Kefala1, Memnon Lysandrou1, Vassiliki Zacharioudaki1, Nikos Tsolakos2, Alexandros Spyridonidis1 1Institute of Cell Therapy, Bone Marrow Transplantation Lab, Department of Medicine, University of Patras, 2Protatonce Ltd, Demokritos Science Park JoVE 65097 Bioengineering