Angela Santoni Department of Molecular Medicine University of Rome “Sapienza” Biography Publications Institution JoVE Articles Angela Santoni has not added a biography. If you are Angela Santoni and would like to personalize this page please email our Author Liaison for assistance. Publications The Senescence-Associated Secretory Phenotype (SASP) in the Challenging Future of Cancer Therapy and Age-Related Diseases Biology. Dec, 2020 | Pubmed ID: 33371508 Regulation of PD-L1 Expression by NF-κB in Cancer Frontiers in Immunology. 2020 | Pubmed ID: 33324403 Chronic Cancer and Non Cancer Pain and Opioid-induced Hyperalgesia Share Common Mechanisms: Neuroinflammation and Central Sensitization Minerva Anestesiologica. Dec, 2020 | Pubmed ID: 33300326 Synthesis and Use of an Amphiphilic Dendrimer for SiRNA Delivery into Primary Immune Cells Nature Protocols. Dec, 2020 | Pubmed ID: 33277630 Immunology and Algology Speak a Common Language - Editorial Immunology Letters. Nov, 2020 | Pubmed ID: 33232719 Liver X Receptors: Regulators of Cholesterol Metabolism, Inflammation, Autoimmunity, and Cancer Frontiers in Immunology. 2020 | Pubmed ID: 33224146 SAMHD1 Phosphorylation and Cytoplasmic Relocalization After Human Cytomegalovirus Infection Limits Its Antiviral Activity PLoS Pathogens. 09, 2020 | Pubmed ID: 32986788 The Global Response to the COVID-19 Pandemic: How Have Immunology Societies Contributed? Nature Reviews. Immunology. 10, 2020 | Pubmed ID: 32913283 FcεRI Signaling in the Modulation of Allergic Response: Role of Mast Cell-Derived Exosomes International Journal of Molecular Sciences. Jul, 2020 | Pubmed ID: 32751734 Tumor Inhibition or Tumor Promotion? The Duplicity of CXCR3 in Cancer Journal of Leukocyte Biology. 08, 2020 | Pubmed ID: 32745326 Neutrophil Diversity and Plasticity in Tumour Progression and Therapy Nature Reviews. Cancer. 09, 2020 | Pubmed ID: 32694624 The Ambiguity of Opioids Revealed by Immunology is Changing the Knowledge and the Therapeutic Approach in Cancer and Non-cancer Pain: A Narrative Review Immunology Letters. 10, 2020 | Pubmed ID: 32590120 Involvement of the TRPML Mucolipin Channels in Viral Infections and Anti-viral Innate Immune Responses Frontiers in Immunology. 2020 | Pubmed ID: 32425938 Natural Killer Cells Modulate Motor Neuron-immune Cell Cross Talk in Models of Amyotrophic Lateral Sclerosis Nature Communications. 04, 2020 | Pubmed ID: 32286313 NKG2D Ligand Shedding in Response to Stress: Role of ADAM10 Frontiers in Immunology. 2020 | Pubmed ID: 32269567 Bone Marrow Stromal Cell-Derived IL-8 Upregulates PVR Expression on Multiple Myeloma Cells Via NF-kB Transcription Factor Cancers. Feb, 2020 | Pubmed ID: 32069911 Gut Microbiota Alterations Affect Glioma Growth and Innate Immune Cells Involved in Tumor Immunosurveillance in Mice European Journal of Immunology. 05, 2020 | Pubmed ID: 32034922 CD155: A Multi-Functional Molecule in Tumor Progression International Journal of Molecular Sciences. Jan, 2020 | Pubmed ID: 32019260 CD16 Pre-ligation by Defucosylated Tumor-targeting MAb Sensitizes Human NK Cells to γ Cytokine Stimulation Via PI3K/mTOR Axis Cancer Immunology, Immunotherapy : CII. Apr, 2020 | Pubmed ID: 31950225 Hitting More Birds with a Stone: Impact of TGF-β on ILC Activity in Cancer Journal of Clinical Medicine. Jan, 2020 | Pubmed ID: 31948072 Cancer Extracellular Vesicles As Novel Regulators of NK Cell Response Cytokine & Growth Factor Reviews. 02, 2020 | Pubmed ID: 31837917 Immune Complexes Exposed on Mast Cell-derived Nanovesicles Amplify Allergic Inflammation Allergy. 05, 2020 | Pubmed ID: 31713871 Post-translational Mechanisms Regulating NK Cell Activating Receptors and Their Ligands in Cancer: Potential Targets for Therapeutic Intervention Frontiers in Immunology. 2019 | Pubmed ID: 31736972 NK Cell Reconstitution in Paediatric Leukemic Patients After T-Cell-Depleted HLA-Haploidentical Haematopoietic Stem Cell Transplantation Followed by the Reinfusion of ICasp9-Modified Donor T Cells Journal of Clinical Medicine. Nov, 2019 | Pubmed ID: 31703320 Targeting of CXCR3 Improves Anti-myeloma Efficacy of Adoptively Transferred Activated Natural Killer Cells Journal for Immunotherapy of Cancer. 11, 2019 | Pubmed ID: 31699153 Transcriptional, Epigenetic and Pharmacological Control of JAK/STAT Pathway in NK Cells Frontiers in Immunology. 2019 | Pubmed ID: 31681330 Guidelines for the Use of Flow Cytometry and Cell Sorting in Immunological Studies (second Edition) European Journal of Immunology. Oct, 2019 | Pubmed ID: 31633216 An Optimized Retinoic Acid-inducible Gene I Agonist M8 Induces Immunogenic Cell Death Markers in Human Cancer Cells and Dendritic Cell Activation Cancer Immunology, Immunotherapy : CII. Sep, 2019 | Pubmed ID: 31463653 Bone Marrow NK Cells: Origin, Distinctive Features, and Requirements for Tissue Localization Frontiers in Immunology. 2019 | Pubmed ID: 31354722 The POU-Domain Transcription Factor Oct-6/POU3F1 As a Regulator of Cellular Response to Genotoxic Stress Cancers. Jun, 2019 | Pubmed ID: 31212703 Activation of Liver X Receptor Up-regulates the Expression of the NKG2D Ligands MICA and MICB in Multiple Myeloma Through Different Molecular Mechanisms FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 08, 2019 | Pubmed ID: 31125275 The Homeobox Transcription Factor MEIS2 is a Regulator of Cancer Cell Survival and IMiDs Activity in Multiple Myeloma: Modulation by Bromodomain and Extra-Terminal (BET) Protein Inhibitors Cell Death & Disease. 04, 2019 | Pubmed ID: 30975979 The Ubiquitin-proteasome Pathway Regulates Nectin2/CD112 Expression and Impairs NK Cell Recognition and Killing European Journal of Immunology. 06, 2019 | Pubmed ID: 30888046 Memory NK Cell Features Exploitable in Anticancer Immunotherapy Journal of Immunology Research. 2019 | Pubmed ID: 30882007 Senescent Cells: Living or Dying is a Matter of NK Cells Journal of Leukocyte Biology. 06, 2019 | Pubmed ID: 30811627 Dendritic Cells Modulate C-kit Expression on the Edge Between Activation and Death European Journal of Immunology. 04, 2019 | Pubmed ID: 30758056 Negative Regulation of Innate Lymphoid Cell Responses in Inflammation and Cancer Immunology Letters. 11, 2019 | Pubmed ID: 30711614 Cancer Exosomes As Conveyors of Stress-Induced Molecules: New Players in the Modulation of NK Cell Response International Journal of Molecular Sciences. Jan, 2019 | Pubmed ID: 30708970 Vaccines: An Achievement of Civilization, a Human Right, Our Health Insurance for the Future The Journal of Experimental Medicine. 01, 2019 | Pubmed ID: 30510147 Antigen-specific CD8 T Cells in Cell Cycle Circulate in the Blood After Vaccination Scandinavian Journal of Immunology. Feb, 2019 | Pubmed ID: 30488973 Key Role of the CD56CD16 Natural Killer Cell Subset in the Recognition and Killing of Multiple Myeloma Cells Cancers. Nov, 2018 | Pubmed ID: 30501078 Translating the Anti-myeloma Activity of Natural Killer Cells into Clinical Application Cancer Treatment Reviews. Nov, 2018 | Pubmed ID: 30326421 JAK/STAT Signaling in Regulation of Innate Lymphoid Cells: The Gods Before the Guardians Immunological Reviews. 11, 2018 | Pubmed ID: 30294965 The Yin-yang of the Interaction Between Myelomonocytic Cells and NK Cells Scandinavian Journal of Immunology. Sep, 2018 | Pubmed ID: 30048003 Ca-activated K Channels Modulate Microglia Affecting Motor Neuron Survival in HSOD1 Mice Brain, Behavior, and Immunity. 10, 2018 | Pubmed ID: 29981425 "Immuno-Transient Receptor Potential Ion Channels": The Role in Monocyte- and Macrophage-Mediated Inflammatory Responses Frontiers in Immunology. 2018 | Pubmed ID: 29928281 HMENA Isoforms Impact NSCLC Patient Outcome Through Fibronectin/β1 Integrin Axis Oncogene. 10, 2018 | Pubmed ID: 29907768 Re: Gut Microbiome Influences Efficacy of PD-1-based Immunotherapy Against Epithelial Tumors European Urology. 10, 2018 | Pubmed ID: 29891391 Tumor-Targeting Anti-CD20 Antibodies Mediate Expansion of Memory Natural Killer Cells: Impact of CD16 Affinity Ligation Conditions and Priming Frontiers in Immunology. 2018 | Pubmed ID: 29867997 MICA-129 Dimorphism and Soluble MICA Are Associated With the Progression of Multiple Myeloma Frontiers in Immunology. 2018 | Pubmed ID: 29765374 Drug-Induced Senescent Multiple Myeloma Cells Elicit NK Cell Proliferation by Direct or Exosome-Mediated IL15 -Presentation Cancer Immunology Research. 07, 2018 | Pubmed ID: 29691234 NKG2D and Its Ligands: "One for All, All for One" Frontiers in Immunology. 2018 | Pubmed ID: 29662484 Impact of Bone Marrow-derived Signals on NK Cell Development and Functional Maturation Cytokine & Growth Factor Reviews. 08, 2018 | Pubmed ID: 29622473 NCR ILC3 Maintain Larger STAT4 Reservoir Via T-BET to Regulate Type 1 Features Upon IL-23 Stimulation in Mice European Journal of Immunology. 07, 2018 | Pubmed ID: 29524223 Chemokine Regulation of Innate Lymphoid Cell Tissue Distribution and Function Cytokine & Growth Factor Reviews. 08, 2018 | Pubmed ID: 29472011 Hepatitis C Virus Direct-acting Antivirals Therapy Impacts on Extracellular Vesicles MicroRNAs Content and on Their Immunomodulating Properties Liver International : Official Journal of the International Association for the Study of the Liver. 10, 2018 | Pubmed ID: 29359389 Effect of Once-daily, Modified-release Hydrocortisone Versus Standard Glucocorticoid Therapy on Metabolism and Innate Immunity in Patients with Adrenal Insufficiency (DREAM): a Single-blind, Randomised Controlled Trial The Lancet. Diabetes & Endocrinology. 03, 2018 | Pubmed ID: 29229498 Multicolor Flow Cytometric Analysis of TLR2 and TLR9 Expression and Function in NK Cells from Patients with ANCA-associated Vasculitis Cytometry. Part B, Clinical Cytometry. 05, 2018 | Pubmed ID: 28834234 Environmental Stimuli Shape Microglial Plasticity in Glioma ELife. 12, 2017 | Pubmed ID: 29286001 How Mucosal Epithelia Deal with Stress: Role of NKG2D/NKG2D Ligands During Inflammation Frontiers in Immunology. 2017 | Pubmed ID: 29209320 IL-1R8 is a Checkpoint in NK Cells Regulating Anti-tumour and Anti-viral Activity Nature. 11, 2017 | Pubmed ID: 29072292 Natural Killer Cell Response to Chemotherapy-Stressed Cancer Cells: Role in Tumor Immunosurveillance Frontiers in Immunology. 2017 | Pubmed ID: 28993779 Reconstitution of Multifunctional CD56CD16 Natural Killer Cell Subset in Children with Acute Leukemia Given α/β T Cell-depleted HLA-haploidentical Haematopoietic Stem Cell Transplantation Oncoimmunology. 2017 | Pubmed ID: 28932646 Innate Immune Activating Ligand SUMOylation Affects Tumor Cell Recognition by NK Cells Scientific Reports. 09, 2017 | Pubmed ID: 28874810 Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis International Journal of Molecular Sciences. Aug, 2017 | Pubmed ID: 28767057 Identification of a Genetic Variation in ERAP1 Aminopeptidase That Prevents Human Cytomegalovirus MiR-UL112-5p-Mediated Immunoevasion Cell Reports. 07, 2017 | Pubmed ID: 28746870 Peripheral Blood T Cell Alterations in Newly Diagnosed Diffuse Large B Cell Lymphoma Patients and Their Long-term Dynamics Upon Rituximab-based Chemoimmunotherapy Cancer Immunology, Immunotherapy : CII. Oct, 2017 | Pubmed ID: 28555258 Docosahexaenoic Acid (DHA) Promotes Immunogenic Apoptosis in Human Multiple Myeloma Cells, Induces Autophagy and Inhibits STAT3 in Both Tumor and Dendritic Cells Genes & Cancer. Jan, 2017 | Pubmed ID: 28435516 Obinutuzumab-mediated High-affinity Ligation of FcγRIIIA/CD16 Primes NK Cells for IFNγ Production Oncoimmunology. 2017 | Pubmed ID: 28405525 Genotoxic Stress Modulates the Release of Exosomes from Multiple Myeloma Cells Capable of Activating NK Cell Cytokine Production: Role of HSP70/TLR2/NF-kB Axis Oncoimmunology. 2017 | Pubmed ID: 28405503 Role of Distinct Natural Killer Cell Subsets in Anticancer Response Frontiers in Immunology. 2017 | Pubmed ID: 28360915 High Expression Levels of IP10/CXCL10 Are Associated with Modulation of the Natural Killer Cell Compartment in Multiple Myeloma Leukemia & Lymphoma. 10, 2017 | Pubmed ID: 28278706 The Multifunctional Role of the Chemokine System in Arthritogenic Processes Current Rheumatology Reports. Mar, 2017 | Pubmed ID: 28265846 GM-CSF Inhibits C-Kit and SCF Expression by Bone Marrow-Derived Dendritic Cells Frontiers in Immunology. 2017 | Pubmed ID: 28261209 P38 MAPK Differentially Controls NK Activating Ligands at Transcriptional and Post-transcriptional Level on Multiple Myeloma Cells Oncoimmunology. 2017 | Pubmed ID: 28197392 CXCR3/CXCL10 Axis Regulates Neutrophil-NK Cell Cross-Talk Determining the Severity of Experimental Osteoarthritis Journal of Immunology (Baltimore, Md. : 1950). 03, 2017 | Pubmed ID: 28108560 Axitinib Induces Senescence-associated Cell Death and Necrosis in Glioma Cell Lines: The Proteasome Inhibitor, Bortezomib, Potentiates Axitinib-induced Cytotoxicity in a P21(Waf/Cip1) Dependent Manner Oncotarget. Jan, 2017 | Pubmed ID: 27926485 Targeting NKG2D and NKp30 Ligands Shedding to Improve NK Cell-Based Immunotherapy Critical Reviews in Immunology. 2016 | Pubmed ID: 28845754 Inhibition of Bromodomain and Extra-terminal (BET) Proteins Increases NKG2D Ligand MICA Expression and Sensitivity to NK Cell-mediated Cytotoxicity in Multiple Myeloma Cells: Role of CMYC-IRF4-miR-125b Interplay Journal of Hematology & Oncology. 12, 2016 | Pubmed ID: 27903272 Natural Killer Cell Recognition of Drug-induced Senescent Multiple Myeloma Cells Oncoimmunology. 2016 | Pubmed ID: 27853638 Post-transcriptional Regulation of 5'-untranslated Regions of Human Transient Receptor Potential Vanilloid Type-1 (TRPV-1) Channels: Role in the Survival of Glioma Patients Oncotarget. Dec, 2016 | Pubmed ID: 27829230 NK Cell Effector Functions in a Chédiak-Higashi Patient Undergoing Cord Blood Transplantation: Effects of in Vitro Treatment with IL-2 Immunology Letters. 12, 2016 | Pubmed ID: 27816481 Dysregulation of Chemokine/Chemokine Receptor Axes and NK Cell Tissue Localization During Diseases Frontiers in Immunology. 2016 | Pubmed ID: 27766097 Distinct Roles for Human Cytomegalovirus Immediate Early Proteins IE1 and IE2 in the Transcriptional Regulation of MICA and PVR/CD155 Expression Journal of Immunology (Baltimore, Md. : 1950). 11, 2016 | Pubmed ID: 27733551 Regulation of NKG2D Expression and Signaling by Endocytosis Trends in Immunology. 11, 2016 | Pubmed ID: 27667711 Polyfunctional Melan-A-specific Tumor-reactive CD8(+) T Cells Elicited by Dacarbazine Treatment Before Peptide-vaccination Depends on AKT Activation Sustained by ICOS Oncoimmunology. May, 2016 | Pubmed ID: 27467927 Immunoregulatory and Effector Activities of Nitric Oxide and Reactive Nitrogen Species in Cancer Current Medicinal Chemistry. 2016 | Pubmed ID: 27464520 Melanoma and Immunotherapy Bridge 2015 : Naples, Italy. 1-5 December 2015 Journal of Translational Medicine. 07, 2016 | Pubmed ID: 27461275 Overexpression of Transient Receptor Potential Mucolipin-2 Ion Channels in Gliomas: Role in Tumor Growth and Progression Oncotarget. Jul, 2016 | Pubmed ID: 27248469 Epitelial-to-mesenchimal Transition and Invasion Are Upmodulated by Tumor-expressed Granzyme B and Inhibited by Docosahexaenoic Acid in Human Colorectal Cancer Cells Journal of Experimental & Clinical Cancer Research : CR. Feb, 2016 | Pubmed ID: 26830472 Regulation and Trafficking of the HLA-E Molecules During Monocyte-macrophage Differentiation Journal of Leukocyte Biology. Jan, 2016 | Pubmed ID: 26310830 Natural Killer (NK) Cells and Anti-tumor Therapeutic MAb: Unexplored Interactions Journal of Leukocyte Biology. Jan, 2016 | Pubmed ID: 26136506 Effector Functions of Natural Killer Cell Subsets in the Control of Hematological Malignancies Frontiers in Immunology. 2015 | Pubmed ID: 26594216 Ubiquitin-dependent Endocytosis of NKG2D-DAP10 Receptor Complexes Activates Signaling and Functions in Human NK Cells Science Signaling. Oct, 2015 | Pubmed ID: 26508790 Axitinib Induces DNA Damage Response Leading to Senescence, Mitotic Catastrophe, and Increased NK Cell Recognition in Human Renal Carcinoma Cells Oncotarget. Nov, 2015 | Pubmed ID: 26474283 The Human Antibody Fragment DIATHIS1 Specific for CEACAM1 Enhances Natural Killer Cell Cytotoxicity Against Melanoma Cell Lines in Vitro Journal of Immunotherapy (Hagerstown, Md. : 1997). Nov-Dec, 2015 | Pubmed ID: 26448580 Multiple Myeloma Impairs Bone Marrow Localization of Effector Natural Killer Cells by Altering the Chemokine Microenvironment Cancer Research. Nov, 2015 | Pubmed ID: 26438594 Response to Comment on Multifunctional Human CD56low CD16low NK Cells Are the Prominent Subset in Bone Marrow of Both Pediatric Healthy Donors and Leukemic Patients Haematologica. Aug, 2015 | Pubmed ID: 26314084 In Vivo Imaging of Natural Killer Cell Trafficking in Tumors Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Oct, 2015 | Pubmed ID: 26272812 The IMiDs Targets IKZF-1/3 and IRF4 As Novel Negative Regulators of NK Cell-activating Ligands Expression in Multiple Myeloma Oncotarget. Sep, 2015 | Pubmed ID: 26269456 The Multifaceted Role of PIP2 in Leukocyte Biology Cellular and Molecular Life Sciences : CMLS. Dec, 2015 | Pubmed ID: 26265181 Anti-CD20 Therapy Acts Via FcγRIIIA to Diminish Responsiveness of Human Natural Killer Cells Cancer Research. Oct, 2015 | Pubmed ID: 26229120 NKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple Myeloma BioMed Research International. 2015 | Pubmed ID: 26161387 Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells Journal of Immunology (Baltimore, Md. : 1950). Jul, 2015 | Pubmed ID: 26071561 Tumor-associated and Immunochemotherapy-dependent Long-term Alterations of the Peripheral Blood NK Cell Compartment in DLBCL Patients Oncoimmunology. 03, 2015 | Pubmed ID: 25949906 Enriched Environment Reduces Glioma Growth Through Immune and Non-immune Mechanisms in Mice Nature Communications. Mar, 2015 | Pubmed ID: 25818172 Nitric Oxide Donors Increase PVR/CD155 DNAM-1 Ligand Expression in Multiple Myeloma Cells: Role of DNA Damage Response Activation BMC Cancer. Jan, 2015 | Pubmed ID: 25609078 Multifunctional Human CD56 Low CD16 Low Natural Killer Cells Are the Prominent Subset in Bone Marrow of Both Healthy Pediatric Donors and Leukemic Patients Haematologica. Apr, 2015 | Pubmed ID: 25596273 NK Cells and Interferons Cytokine & Growth Factor Reviews. Apr, 2015 | Pubmed ID: 25443799 Capsaicin-mediated Apoptosis of Human Bladder Cancer Cells Activates Dendritic Cells Via CD91 Nutrition (Burbank, Los Angeles County, Calif.). Apr, 2015 | Pubmed ID: 25220876 Regulation of Fc Receptor Endocytic Trafficking by Ubiquitination Frontiers in Immunology. 2014 | Pubmed ID: 25278942 Reactive Oxygen Species- and DNA Damage Response-dependent NK Cell Activating Ligand Upregulation Occurs at Transcriptional Levels and Requires the Transcriptional Factor E2F1 Journal of Immunology (Baltimore, Md. : 1950). Jul, 2014 | Pubmed ID: 24913980 C-Cbl Regulates MICA- but Not ULBP2-induced NKG2D Down-modulation in Human NK Cells European Journal of Immunology. Sep, 2014 | Pubmed ID: 24846123 Recognition of Adult and Pediatric Acute Lymphoblastic Leukemia Blasts by Natural Killer Cells Haematologica. Jul, 2014 | Pubmed ID: 24658822 Multiple Levels of Chemokine Receptor Regulation in the Control of Mouse Natural Killer Cell Development Frontiers in Immunology. 2014 | Pubmed ID: 24592263 The DNA Damage Response: A Common Pathway in the Regulation of NKG2D and DNAM-1 Ligand Expression in Normal, Infected, and Cancer Cells Frontiers in Immunology. Jan, 2014 | Pubmed ID: 24432022 Cancer-associated CD43 Glycoforms As Target of Immunotherapy Molecular Cancer Therapeutics. Mar, 2014 | Pubmed ID: 24356816 Chemotherapy-elicited Upregulation of NKG2D and DNAM-1 Ligands As a Therapeutic Target in Multiple Myeloma Oncoimmunology. Dec, 2013 | Pubmed ID: 24498552 Activation of Lymphocyte Cytolytic Machinery: Where Are We? Frontiers in Immunology. Nov, 2013 | Pubmed ID: 24312097 Inhibition of Glycogen Synthase Kinase-3 Increases NKG2D Ligand MICA Expression and Sensitivity to NK Cell-mediated Cytotoxicity in Multiple Myeloma Cells: Role of STAT3 Journal of Immunology (Baltimore, Md. : 1950). Jun, 2013 | Pubmed ID: 23686482 Differential Chemotactic Receptor Requirements for NK Cell Subset Trafficking into Bone Marrow Frontiers in Immunology. 2013 | Pubmed ID: 23386850 NKG2D and DNAM-1 Activating Receptors and Their Ligands in NK-T Cell Interactions: Role in the NK Cell-mediated Negative Regulation of T Cell Responses Frontiers in Immunology. 2012 | Pubmed ID: 23316196 Splicing Program of Human MENA Produces a Previously Undescribed Isoform Associated with Invasive, Mesenchymal-like Breast Tumors Proceedings of the National Academy of Sciences of the United States of America. Nov, 2012 | Pubmed ID: 23129656 Chemerin Regulates NK Cell Accumulation and Endothelial Cell Morphogenesis in the Decidua During Early Pregnancy The Journal of Clinical Endocrinology and Metabolism. Oct, 2012 | Pubmed ID: 22791765 Syk-dependent Regulation of Hrs Phosphorylation and Ubiquitination Upon FcεRI Engagement: Impact on Hrs Membrane/cytosol Localization European Journal of Immunology. Oct, 2012 | Pubmed ID: 22706924 Interplay Between Human Cytomegalovirus and Intrinsic/innate Host Responses: a Complex Bidirectional Relationship Mediators of Inflammation. 2012 | Pubmed ID: 22701276 Chemokines and NK Cells: Regulators of Development, Trafficking and Functions Immunology Letters. Jul, 2012 | Pubmed ID: 22698182 IL-15 Inhibits IL-7Rα Expression by Memory-phenotype CD8⁺ T Cells in the Bone Marrow European Journal of Immunology. May, 2012 | Pubmed ID: 22539288 The Human Immunodeficiency Virus Type 1 Nef and Vpu Proteins Downregulate the Natural Killer Cell-activating Ligand PVR Journal of Virology. Apr, 2012 | Pubmed ID: 22301152 NKG2D/Ligand Dysregulation and Functional Alteration of Innate Immunity Cell Populations in Pediatric IBD Inflammatory Bowel Diseases. Oct, 2012 | Pubmed ID: 22294522 PIP2-dependent Regulation of Munc13-4 Endocytic Recycling: Impact on the Cytolytic Secretory Pathway Blood. Mar, 2012 | Pubmed ID: 22271450 Ex Vivo Acidic Preconditioning Enhances Bone Marrow Ckit+ Cell Therapeutic Potential Via Increased CXCR4 Expression European Heart Journal. Jul, 2011 | Pubmed ID: 21784762 Transcriptional Modulation of a Human Monocytic Cell Line Exposed to PM(10) from an Urban Area Environmental Research. Aug, 2011 | Pubmed ID: 21741637 Cbl Family Proteins: Balancing FcεRI-mediated Mast Cell and Basophil Activation International Archives of Allergy and Immunology. 2011 | Pubmed ID: 21447956 DNAM-1 Ligand Expression on Ag-stimulated T Lymphocytes is Mediated by ROS-dependent Activation of DNA-damage Response: Relevance for NK-T Cell Interaction Blood. May, 2011 | Pubmed ID: 21406724 CX3CR1 Expression Defines 2 KLRG1+ Mouse NK-cell Subsets with Distinct Functional Properties and Positioning in the Bone Marrow Blood. Apr, 2011 | Pubmed ID: 21364193 The Cooperation Between HMena Overexpression and HER2 Signalling in Breast Cancer PloS One. Dec, 2010 | Pubmed ID: 21209853 Peripheral and Intestinal CD4+ T Cells with a Regulatory Phenotype in Pediatric Patients with Inflammatory Bowel Disease Journal of Pediatric Gastroenterology and Nutrition. Nov, 2010 | Pubmed ID: 20890221 Chemokines and Glioma: Invasion and More Journal of Neuroimmunology. Jul, 2010 | Pubmed ID: 20656128 Ubiquitination and Endocytosis of the High Affinity Receptor for IgE Molecular Immunology. Sep, 2010 | Pubmed ID: 20638130 CX3CR1/CX3CL1 Axis Negatively Controls Glioma Cell Invasion and is Modulated by Transforming Growth Factor-β1 Neuro-oncology. Jul, 2010 | Pubmed ID: 20511186 Attenuation of PI3K/Akt-mediated Tumorigenic Signals Through PTEN Activation by DNA Vaccine-induced Anti-ErbB2 Antibodies Journal of Immunology (Baltimore, Md. : 1950). Apr, 2010 | Pubmed ID: 20220087 Impaired NK-cell Migration in WAS/XLT Patients: Role of Cdc42/WASp Pathway in the Control of Chemokine-induced Beta2 Integrin High-affinity State Blood. Apr, 2010 | Pubmed ID: 20130240 Insulin Potentiates FcepsilonRI-mediated Signaling in Mouse Bone Marrow-derived Mast Cells Molecular Immunology. Feb, 2010 | Pubmed ID: 20004975 Heat Shock Protein-90 Inhibitors Increase MHC Class I-related Chain A and B Ligand Expression on Multiple Myeloma Cells and Their Ability to Trigger NK Cell Degranulation Journal of Immunology (Baltimore, Md. : 1950). Oct, 2009 | Pubmed ID: 19748980 Lipid Raft-dependent FcepsilonRI Ubiquitination Regulates Receptor Endocytosis Through the Action of Ubiquitin Binding Adaptors PloS One. 2009 | Pubmed ID: 19440386 Detuning CD8+ T Lymphocytes by Down-regulation of the Activating Receptor NKG2D: Role of NKG2D Ligands Released by Activated T Cells Blood. Mar, 2009 | Pubmed ID: 19124832 Kinetics of in Vivo Proliferation and Death of Memory and Naive CD8 T Cells: Parameter Estimation Based on 5-bromo-2'-deoxyuridine Incorporation in Spleen, Lymph Nodes, and Bone Marrow Journal of Immunology (Baltimore, Md. : 1950). Jun, 2008 | Pubmed ID: 18490722 Mechanisms Underlying Recruitment and Accumulation of Decidual NK Cells in Uterus During Pregnancy American Journal of Reproductive Immunology (New York, N.Y. : 1989). May, 2008 | Pubmed ID: 18405312 Uterine NK Cell Development, Migration and Function Reproductive Biomedicine Online. Feb, 2008 | Pubmed ID: 18284874 CCL3 and CXCL12 Regulate Trafficking of Mouse Bone Marrow NK Cell Subsets Blood. Apr, 2008 | Pubmed ID: 18227348 Recruitment of Circulating NK Cells Through Decidual Tissues: a Possible Mechanism Controlling NK Cell Accumulation in the Uterus During Early Pregnancy Blood. Mar, 2008 | Pubmed ID: 18187664 Increased Frequency of Human Leukocyte Antigen-E Inhibitory Receptor CD94/NKG2A-expressing Peritoneal Natural Killer Cells in Patients with Endometriosis Fertility and Sterility. May, 2008 | Pubmed ID: 17706207 Pathophysiology of Ageing, Longevity and Age Related Diseases Immunity & Ageing : I & A. Aug, 2007 | Pubmed ID: 17683521 Natural Killer (NK) Cells from Killers to Regulators: Distinct Features Between Peripheral Blood and Decidual NK Cells American Journal of Reproductive Immunology (New York, N.Y. : 1989). Sep, 2007 | Pubmed ID: 17681044 The Adaptor Molecule CIN85 Regulates Syk Tyrosine Kinase Level by Activating the Ubiquitin-proteasome Degradation Pathway Journal of Immunology (Baltimore, Md. : 1950). Aug, 2007 | Pubmed ID: 17675467 Inhibition of Trail Gene Expression by Cyclopentenonic Prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in T Lymphocytes Molecular Pharmacology. Nov, 2007 | Pubmed ID: 17673570 Negative Signals from FcepsilonRI Engagement Attenuate Mast Cell Functions Archivum Immunologiae Et Therapiae Experimentalis. Jul-Aug, 2007 | Pubmed ID: 17659377 Antigen-activated Human T Lymphocytes Express Cell-surface NKG2D Ligands Via an ATM/ATR-dependent Mechanism and Become Susceptible to Autologous NK- Cell Lysis Blood. Jul, 2007 | Pubmed ID: 17405908 15-deoxy-Delta12,14-prostaglandin J2 Negatively Regulates Rankl Gene Expression in Activated T Lymphocytes: Role of NF-kappaB and Early Growth Response Transcription Factors Journal of Immunology (Baltimore, Md. : 1950). Apr, 2007 | Pubmed ID: 17371958 Molecular Cloning of HMena (ENAH) and Its Splice Variant HMena+11a: Epidermal Growth Factor Increases Their Expression and Stimulates HMena+11a Phosphorylation in Breast Cancer Cell Lines Cancer Research. Mar, 2007 | Pubmed ID: 17363586 Human Immunodeficiency Virus 1 Nef Protein Downmodulates the Ligands of the Activating Receptor NKG2D and Inhibits Natural Killer Cell-mediated Cytotoxicity The Journal of General Virology. Jan, 2007 | Pubmed ID: 17170457 High-efficient Lentiviral Vector-mediated Gene Transfer into Primary Human NK Cells Experimental Hematology. Oct, 2006 | Pubmed ID: 16982327 CIN85 Regulates the Ligand-dependent Endocytosis of the IgE Receptor: a New Molecular Mechanism to Dampen Mast Cell Function Journal of Immunology (Baltimore, Md. : 1950). Oct, 2005 | Pubmed ID: 16177060 Chemoattractant Induces LFA-1 Associated PI 3K Activity and Cell Migration That Are Dependent on Fyn Signaling FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2005 | Pubmed ID: 15955842 Arf6: a New Player in FcgammaRIIIA Lymphocyte-mediated Cytotoxicity Blood. Jul, 2005 | Pubmed ID: 15817676 Hyperthermia Enhances CD95-ligand Gene Expression in T Lymphocytes Journal of Immunology (Baltimore, Md. : 1950). Jan, 2005 | Pubmed ID: 15611244 P38 MAPK Activation Controls the TLR3-mediated Up-regulation of Cytotoxicity and Cytokine Production in Human NK Cells Blood. Dec, 2004 | Pubmed ID: 15315972 Noncompetitive Allosteric Inhibitors of the Inflammatory Chemokine Receptors CXCR1 and CXCR2: Prevention of Reperfusion Injury Proceedings of the National Academy of Sciences of the United States of America. Aug, 2004 | Pubmed ID: 15282370 Impaired Natural and CD16-mediated NK Cell Cytotoxicity in Patients with WAS and XLT: Ability of IL-2 to Correct NK Cell Functional Defect Blood. Jul, 2004 | Pubmed ID: 15001467 In Vitro and in Vivo Models to Study Chemokine Regulation of Angiogenesis Methods in Molecular Biology (Clifton, N.J.). 2004 | Pubmed ID: 14573922 Evaluation of Rho Family Small G-protein Activity Induced by Integrin Ligation on Human Leukocytes Methods in Molecular Biology (Clifton, N.J.). 2004 | Pubmed ID: 14573910 The Cyclopentenone-type Prostaglandin 15-deoxy-delta 12,14-prostaglandin J2 Inhibits CD95 Ligand Gene Expression in T Lymphocytes: Interference with Promoter Activation Via Peroxisome Proliferator-activated Receptor-gamma-independent Mechanisms Journal of Immunology (Baltimore, Md. : 1950). May, 2003 | Pubmed ID: 12707336 Proline-rich Tyrosine Kinase 2 and Rac Activation by Chemokine and Integrin Receptors Controls NK Cell Transendothelial Migration Journal of Immunology (Baltimore, Md. : 1950). Mar, 2003 | Pubmed ID: 12626562 Memory T-cell Competition for Bone Marrow Seeding Immunology. Mar, 2003 | Pubmed ID: 12603595 Defective Expression of the T-cell Receptor-CD3 Zeta Chain in T-cell Acute Lymphoblastic Leukaemia British Journal of Haematology. Jan, 2003 | Pubmed ID: 12542476 Analysis of the Role of Chemokines in Angiogenesis Journal of Immunological Methods. Feb, 2003 | Pubmed ID: 12535800 SH2-containing Inositol Phosphatase (SHIP-1) Transiently Translocates to Raft Domains and Modulates CD16-mediated Cytotoxicity in Human NK Cells Blood. Dec, 2002 | Pubmed ID: 12393695 Activation of Syk Tyrosine Kinase is Required for C-Cbl-mediated Ubiquitination of Fcepsilon RI and Syk in RBL Cells The Journal of Biological Chemistry. Oct, 2002 | Pubmed ID: 12145291 Src-dependent Syk Activation Controls CD69-mediated Signaling and Function on Human NK Cells Journal of Immunology (Baltimore, Md. : 1950). Jul, 2002 | Pubmed ID: 12077230 Expansion of Cytotoxic Effectors with Lytic Activity Against Autologous Blasts from Acute Myeloid Leukaemia Patients in Complete Haematological Remission British Journal of Haematology. Feb, 2002 | Pubmed ID: 11841430 Negative Regulation of CD95 Ligand Gene Expression by Vitamin D3 in T Lymphocytes Journal of Immunology (Baltimore, Md. : 1950). Feb, 2002 | Pubmed ID: 11801650 Ubiquitination and Degradation of Syk and ZAP-70 Protein Tyrosine Kinases in Human NK Cells Upon CD16 Engagement Proceedings of the National Academy of Sciences of the United States of America. Aug, 2001 | Pubmed ID: 11493682 Polyclonal Antibodies Against Gp185HER2 Peptides: Their Putative Role in the Identification of a Particular HER2 Status in Patients With Breast Cancer Journal of Immunotherapy : Official Journal of the Society for Biological Therapy. May, 2001 | Pubmed ID: 11395637 The Chemokine Growth-related Gene Product Beta Protects Rat Cerebellar Granule Cells from Apoptotic Cell Death Through Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate Receptors Proceedings of the National Academy of Sciences of the United States of America. May, 2000 | Pubmed ID: 10811878 Integrin-mediated Ras-extracellular Regulated Kinase (ERK) Signaling Regulates Interferon Gamma Production in Human Natural Killer Cells The Journal of Experimental Medicine. Oct, 1998 | Pubmed ID: 9763606 בדיקת ציטומטריית זרימה מבוססת DNA/Ki67 לניתוח מחזור תאים של תאי CD8 T ספציפיים לאנטיגן בעכברים מחוסנים Sonia Simonetti*1,2, Ambra Natalini*1,2, Giovanna Peruzzi3, Alfredo Nicosia4, Antonella Folgori5, Stefania Capone5, Angela Santoni2,6, Francesca Di Rosa1 1Institute of Molecular Biology and Pathology, National Research Council of Italy (CNR), 2Department of Molecular Medicine, University of Rome “Sapienza”, 3Center for Life Nano Science, Istituto Italiano di Tecnologia, 4Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 5Reithera Srl, 6IRCCS, Neuromed JoVE 61867 Immunology and Infection
בדיקת ציטומטריית זרימה מבוססת DNA/Ki67 לניתוח מחזור תאים של תאי CD8 T ספציפיים לאנטיגן בעכברים מחוסנים Sonia Simonetti*1,2, Ambra Natalini*1,2, Giovanna Peruzzi3, Alfredo Nicosia4, Antonella Folgori5, Stefania Capone5, Angela Santoni2,6, Francesca Di Rosa1 1Institute of Molecular Biology and Pathology, National Research Council of Italy (CNR), 2Department of Molecular Medicine, University of Rome “Sapienza”, 3Center for Life Nano Science, Istituto Italiano di Tecnologia, 4Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 5Reithera Srl, 6IRCCS, Neuromed JoVE 61867 Immunology and Infection