Angelika Eggert Department of Pediatric Oncology University Children's Hospital Essen Biography Publications Institution JoVE Articles Angelika Eggert has not added a biography. If you are Angelika Eggert and would like to personalize this page please email our Author Liaison for assistance. Publications [In Process Citation] Krankenpflege. Soins Infirmiers. 2012 | Pubmed ID: 22338269 The Metallophosphodiesterase Mpped2 Impairs Tumorigenesis in Neuroblastoma Cell Cycle (Georgetown, Tex.). Feb, 2012 | Pubmed ID: 22262177 MiRNA Expression Profiling Enables Risk Stratification in Archived and Fresh Neuroblastoma Tumor Samples Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2011 | Pubmed ID: 22031095 Progress in Treatment and Risk Stratification of Neuroblastoma: Impact on Future Clinical and Basic Research Seminars in Cancer Biology. Oct, 2011 | Pubmed ID: 21798350 Identification of a Novel Recurrent 1q42.2-1qter Deletion in High Risk MYCN Single Copy 11q Deleted Neuroblastomas International Journal of Cancer. Journal International Du Cancer. Jul, 2011 | Pubmed ID: 21796619 High ALK Receptor Tyrosine Kinase Expression Supersedes ALK Mutation As a Determining Factor of an Unfavorable Phenotype in Primary Neuroblastoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2011 | Pubmed ID: 21632861 Regulatory BCL2 Promoter Polymorphism (-938C>A) is Associated with Adverse Outcome in Patients with Prostate Carcinoma International Journal of Cancer. Journal International Du Cancer. Nov, 2011 | Pubmed ID: 21207420 Polo-like Kinase 1 is a Therapeutic Target in High-risk Neuroblastoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2011 | Pubmed ID: 21169242 A Small Kiss of Death for Cancer Nature Medicine. Oct, 2010 | Pubmed ID: 20930746 The Quassinoid Derivative NBT-272 Targets Both the AKT and ERK Signaling Pathways in Embryonal Tumors Molecular Cancer Therapeutics. Dec, 2010 | Pubmed ID: 20889731 Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2010 | Pubmed ID: 20719933 Accurate Prediction of Neuroblastoma Outcome Based on MiRNA Expression Profiles International Journal of Cancer. Journal International Du Cancer. Nov, 2010 | Pubmed ID: 20473924 Deep Sequencing Reveals Differential Expression of MicroRNAs in Favorable Versus Unfavorable Neuroblastoma Nucleic Acids Research. Sep, 2010 | Pubmed ID: 20466808 Chromosomal and MicroRNA Expression Patterns Reveal Biologically Distinct Subgroups of 11q- Neuroblastoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2010 | Pubmed ID: 20406844 Accurate Outcome Prediction in Neuroblastoma Across Independent Data Sets Using a Multigene Signature Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2010 | Pubmed ID: 20179214 IL-2-driven Regulation of NK Cell Receptors with Regard to the Distribution of CD16+ and CD16- Subpopulations and in Vivo Influence After Haploidentical NK Cell Infusion Journal of Immunotherapy (Hagerstown, Md. : 1997). Feb-Mar, 2010 | Pubmed ID: 20145545 Neuroblastoma: Biology, Prognosis, and Treatment Hematology/oncology Clinics of North America. Feb, 2010 | Pubmed ID: 20113896 Xenogeneic Immunization with Human Tyrosine Hydroxylase DNA Vaccines Suppresses Growth of Established Neuroblastoma Molecular Cancer Therapeutics. Aug, 2009 | Pubmed ID: 19671753 Meta-mining of Neuroblastoma and Neuroblast Gene Expression Profiles Reveals Candidate Therapeutic Compounds Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2009 | Pubmed ID: 19435837 Reanalysis of Neuroblastoma Expression Profiling Data Using Improved Methodology and Extended Follow-up Increases Validity of Outcome Prediction Cancer Letters. Sep, 2009 | Pubmed ID: 19349112 Lysine-specific Demethylase 1 is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy Cancer Research. Mar, 2009 | Pubmed ID: 19223552 Overall Genomic Pattern is a Predictor of Outcome in Neuroblastoma Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2009 | Pubmed ID: 19171713 The Low-affinity Neurotrophin Receptor, P75, is Upregulated in Ganglioneuroblastoma/ganglioneuroma and Reduces Tumorigenicity of Neuroblastoma Cells in Vivo International Journal of Cancer. Journal International Du Cancer. May, 2009 | Pubmed ID: 19142969 MicroRNAs in the Pathogenesis of Neuroblastoma Cancer Letters. Feb, 2009 | Pubmed ID: 18639376 Expression of the TrkA or TrkB Receptor Tyrosine Kinase Alters the Double-strand Break (DSB) Repair Capacity of SY5Y Neuroblastoma Cells DNA Repair. Oct, 2008 | Pubmed ID: 18678285 Transcription Factor AP2alpha (TFAP2a) Regulates Differentiation and Proliferation of Neuroblastoma Cells Cancer Letters. Nov, 2008 | Pubmed ID: 18620802 Photodynamic Therapy in Retinoblastoma: Effects of Verteporfin on Retinoblastoma Cell Lines Investigative Ophthalmology & Visual Science. Jul, 2008 | Pubmed ID: 18579764 CADM1 is a Strong Neuroblastoma Candidate Gene That Maps Within a 3.72 Mb Critical Region of Loss on 11q23 BMC Cancer. 2008 | Pubmed ID: 18559103 Microarray Analysis of Ewing's Sarcoma Family of Tumours Reveals Characteristic Gene Expression Signatures Associated with Metastasis and Resistance to Chemotherapy European Journal of Cancer (Oxford, England : 1990). Mar, 2008 | Pubmed ID: 18294840 Targeting the Phosphoinositide 3-kinase Isoform P110delta Impairs Growth and Survival in Neuroblastoma Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2008 | Pubmed ID: 18281552 Neuroblastoma: Biology, Prognosis, and Treatment Pediatric Clinics of North America. Feb, 2008 | Pubmed ID: 18242317 Neurotrophin Receptor Expression in Human Primary Retinoblastomas and Retinoblastoma Cell Lines Pediatric Blood & Cancer. Feb, 2008 | Pubmed ID: 17973327 Identification of 2 Putative Critical Segments of 17q Gain in Neuroblastoma Through Integrative Genomics International Journal of Cancer. Journal International Du Cancer. Mar, 2008 | Pubmed ID: 17973261 MYCN Regulates Oncogenic MicroRNAs in Neuroblastoma International Journal of Cancer. Journal International Du Cancer. Feb, 2008 | Pubmed ID: 17943719 ArrayCGH-based Classification of Neuroblastoma into Genomic Subgroups Genes, Chromosomes & Cancer. Dec, 2007 | Pubmed ID: 17823929 The Mutagenic Potential of Non-homologous End Joining in the Absence of the NHEJ Core Factors Ku70/80, DNA-PKcs and XRCC4-LigIV Mutagenesis. May, 2007 | Pubmed ID: 17347130 Fractalkine (CX3CL1)- and Interleukin-2-enriched Neuroblastoma Microenvironment Induces Eradication of Metastases Mediated by T Cells and Natural Killer Cells Cancer Research. Mar, 2007 | Pubmed ID: 17332365 Translating Expression Profiling into a Clinically Feasible Test to Predict Neuroblastoma Outcome Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2007 | Pubmed ID: 17332289 High Resolution Tiling-path BAC Array Deletion Mapping Suggests Commonly Involved 3p21-p22 Tumor Suppressor Genes in Neuroblastoma and More Frequent Tumors International Journal of Cancer. Journal International Du Cancer. Feb, 2007 | Pubmed ID: 17096344 Human Fetal Neuroblast and Neuroblastoma Transcriptome Analysis Confirms Neuroblast Origin and Highlights Neuroblastoma Candidate Genes Genome Biology. 2006 | Pubmed ID: 16989664 Identification of a Set of Seven Genes for the Monitoring of Minimal Residual Disease in Pediatric Acute Myeloid Leukemia Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2006 | Pubmed ID: 16638849 Vascular Endothelial Growth Factor Plasma Levels Are Significantly Elevated in Patients with Cerebral Arteriovenous Malformations Cerebrovascular Diseases (Basel, Switzerland). 2006 | Pubmed ID: 16388189 VEGF Plasma Levels in Non-ruptured Intracranial Aneurysms Neurosurgical Review. Jan, 2006 | Pubmed ID: 16133453 Prediction of Clinical Outcome and Biological Characterization of Neuroblastoma by Expression Profiling Oncogene. Nov, 2005 | Pubmed ID: 16103881 Phox2B Mutations and the Delta-Notch Pathway in Neuroblastoma Cancer Letters. Oct, 2005 | Pubmed ID: 16084642 The Neurotrophin Receptor TrkB Cooperates with C-Met in Enhancing Neuroblastoma Invasiveness Carcinogenesis. Dec, 2005 | Pubmed ID: 16051641 Gains and Overexpression Identify DEK and E2F3 As Targets of Chromosome 6p Gains in Retinoblastoma Oncogene. Sep, 2005 | Pubmed ID: 16007192 Application of Microarray-based Technology to Neuroblastoma Cancer Letters. Oct, 2005 | Pubmed ID: 15951106 Biological Effects of TrkA and TrkB Receptor Signaling in Neuroblastoma Cancer Letters. Oct, 2005 | Pubmed ID: 15921851 Identification of Dynamic Proteome Changes Upon Ligand Activation of Trk-receptors Using Two-dimensional Fluorescence Difference Gel Electrophoresis and Mass Spectrometry Molecular & Cellular Proteomics : MCP. Mar, 2005 | Pubmed ID: 15654083 Microarray Analysis Reveals Differential Gene Expression Patterns and Regulation of Single Target Genes Contributing to the Opposing Phenotype of TrkA- and TrkB-expressing Neuroblastomas Oncogene. Jan, 2005 | Pubmed ID: 15637590 The Phox2B Homeobox Gene is Mutated in Sporadic Neuroblastomas Oncogene. Dec, 2004 | Pubmed ID: 15516980 Angiogenic Cytokines. Quantitative and Functional Analysis Methods in Molecular Biology (Clifton, N.J.). 2003 | Pubmed ID: 12512294 Apoptosis Induction by TRAIL Methods in Molecular Biology (Clifton, N.J.). 2003 | Pubmed ID: 12512293 Resistance to Chemotherapy Mediated by TrkB in Neuroblastomas Cancer Research. Nov, 2002 | Pubmed ID: 12438236 Expression of the Neurotrophin Receptor TrkA Down-regulates Expression and Function of Angiogenic Stimulators in SH-SY5Y Neuroblastoma Cells Cancer Research. Mar, 2002 | Pubmed ID: 11912158 Production of Chick Embryo Extract for the Cultivation of Murine Neural Crest Stem Cells Kristian Pajtler*1, Anna Bohrer*1, Jochen Maurer2, Hubert Schorle2, Alexander Schramm1, Angelika Eggert1, Johannes Hubertus Schulte1 1Department of Pediatric Oncology, University Children's Hospital Essen, 2Department of Developmental Pathology, Bonn Medical School, Institute of Pathology JoVE 2380 Neuroscience
Production of Chick Embryo Extract for the Cultivation of Murine Neural Crest Stem Cells Kristian Pajtler*1, Anna Bohrer*1, Jochen Maurer2, Hubert Schorle2, Alexander Schramm1, Angelika Eggert1, Johannes Hubertus Schulte1 1Department of Pediatric Oncology, University Children's Hospital Essen, 2Department of Developmental Pathology, Bonn Medical School, Institute of Pathology JoVE 2380 Neuroscience