Anil K. Rustgi Herbert Irving Comprehensive Cancer Center Columbia University Biography Publications Institution JoVE Articles Anil K. Rustgi has not added a biography. If you are Anil K. Rustgi and would like to personalize this page please email our Author Liaison for assistance. Publications KMT2D Deficiency Drives Lung Squamous Cell Carcinoma and Hypersensitivity to RTK-RAS Inhibition Cancer Cell. Dec, 2022 | Pubmed ID: 36525973 Tumor Suppressive and Immune-stimulating Roles of Cholesterol 25-hydroxylase in Pancreatic Cancer Cells Molecular Cancer Research : MCR. Nov, 2022 | Pubmed ID: 36378658 Tumor Suppressor Mediated Ubiquitylation of HnRNPK is a Barrier to Oncogenic Translation Nature Communications. Nov, 2022 | Pubmed ID: 36329064 Author Correction: A Cellular Hierarchy in Melanoma Uncouples Growth and Metastasis Nature. Nov, 2022 | Pubmed ID: 36261534 A Cellular Hierarchy in Melanoma Uncouples Growth and Metastasis Nature. Oct, 2022 | Pubmed ID: 36131018 The Multicenter Cancer of Pancreas Screening Study: Impact on Stage and Survival Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2022 | Pubmed ID: 35704792 Presentation of the Julius M. Friedenwald Medal to Timothy C. Wang, MD, AGAF Gastroenterology. Jun, 2022 | Pubmed ID: 35443933 The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis Gastroenterology. Mar, 2022 | Pubmed ID: 34883119 A Clinical Prediction Model to Assess Risk for Pancreatic Cancer Among Patients with Prediabetes European Journal of Gastroenterology & Hepatology. Jan, 2022 | Pubmed ID: 33470698 Patient-derived Organoids As a Platform for Modeling a Patient's Response to Chemoradiotherapy in Esophageal Cancer Scientific Reports. Oct, 2021 | Pubmed ID: 34716381 Screening for Pancreatic Ductal Adenocarcinoma: Are We Asking the Impossible?-Letter Cancer Prevention Research (Philadelphia, Pa.). Oct, 2021 | Pubmed ID: 34607877 Diversity in Leadership at Academic Medical Centers: Addressing Underrepresentation Among Asian American Faculty JAMA. Aug, 2021 | Pubmed ID: 34402820 Single-cell Analysis of Ductal Differentiation Nature Biomedical Engineering. Aug, 2021 | Pubmed ID: 34389821 EUS-based Pancreatic Cancer Surveillance in Carriers Without a Family History of Pancreatic Cancer Cancer Prevention Research (Philadelphia, Pa.). Nov, 2021 | Pubmed ID: 34341011 Calcium Signaling Induces a Partial EMT EMBO Reports. Sep, 2021 | Pubmed ID: 34324787 Multigene Panel Testing in Individuals With Hepatocellular Carcinoma Identifies Pathogenic Germline Variants JCO Precision Oncology. 2021 | Pubmed ID: 34250406 Threshold Analysis of the Cost-effectiveness of Endoscopic Ultrasound in Patients at High Risk for Pancreatic Ductal Adenocarcinoma Pancreas. Jul, 2021 | Pubmed ID: 34149034 Stem Cells and Origins of Cancer in the Upper Gastrointestinal Tract Cell Stem Cell. Aug, 2021 | Pubmed ID: 34129814 Pancreatic Plasticity: Unlocking Exocrine Lineage Specification Cell Stem Cell. Jun, 2021 | Pubmed ID: 34087158 Extracellular ATP and Adenosine in Cancer Pathogenesis and Treatment Trends in Cancer. Aug, 2021 | Pubmed ID: 34074623 Emerging Technologies Provide Insights on Cancer Extracellular Matrix Biology and Therapeutics IScience. May, 2021 | Pubmed ID: 34027324 Reprogramming of the Esophageal Squamous Carcinoma Epigenome by SOX2 Promotes ADAR1 Dependence Nature Genetics. Jun, 2021 | Pubmed ID: 33972779 COVID-19 Related Pancreatic Cancer Surveillance Disruptions Amongst High-risk Individuals Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]. Apr, 2021 | Pubmed ID: 33926820 Gene-Specific Variation in Colorectal Cancer Surveillance Strategies for Lynch Syndrome Gastroenterology. Aug, 2021 | Pubmed ID: 33839100 Artificial Intelligence and Early Detection of Pancreatic Cancer: 2020 Summative Review Pancreas. Mar, 2021 | Pubmed ID: 33835956 LIN28B Induces a Differentiation Program Through CDX2 in Colon Cancer JCI Insight. May, 2021 | Pubmed ID: 33755595 Mutant P53 Regulates Survivin to Foster Lung Metastasis Genes & Development. Apr, 2021 | Pubmed ID: 33737385 PTHrP Drives Pancreatic Cancer Growth and Metastasis and Reveals a New Therapeutic Vulnerability Cancer Discovery. Jul, 2021 | Pubmed ID: 33589425 Rab11-FIP1 Mediates Epithelial-mesenchymal Transition and Invasion in Esophageal Cancer EMBO Reports. Feb, 2021 | Pubmed ID: 33403789 Potential Molecular Targets in the Setting of Chemoradiation for Esophageal Malignancies Journal of the National Cancer Institute. Jun, 2021 | Pubmed ID: 33351071 MTOR Inhibition Acts As an Unexpected Checkpoint in P53-mediated Tumor Suppression Genes & Development. Jan, 2021 | Pubmed ID: 33303641 The Balance of Stromal BMP Signaling Mediated by GREM1 and ISLR Drives Colorectal Carcinogenesis Gastroenterology. 03, 2021 | Pubmed ID: 33197448 Mesenchymal Plasticity Regulated by Prrx1 Drives Aggressive Pancreatic Cancer Biology Gastroenterology. Jan, 2021 | Pubmed ID: 33007300 Growth of Pancreatic Cancers with Hemizygous Chromosomal 17p Loss of Can Be Preferentially Targeted by PARP Inhibitors Science Advances. Dec, 2020 | Pubmed ID: 33277249 2020 American Pancreatic Association Presidential Address: Pancreatology-at the Crossroads Pancreas. 2020 | Pubmed ID: 33122512 EMT, MET, Plasticity, and Tumor Metastasis Trends in Cell Biology. Oct, 2020 | Pubmed ID: 32800658 Our New President-M. Bishr Omary, MD, PhD, AGAF Gastroenterology. May, 2020 | Pubmed ID: 32364115 Notch Signaling Mediates Differentiation in Barrett's Esophagus and Promotes Progression to Adenocarcinoma Gastroenterology. Aug, 2020 | Pubmed ID: 32325086 Generation and Characterization of Patient-Derived Head and Neck, Oral, and Esophageal Cancer Organoids Current Protocols in Stem Cell Biology. Jun, 2020 | Pubmed ID: 32294323 Associations of Sociodemographic and Clinical Factors with Gastrointestinal Cancer Risk Assessment Appointment Completion Journal of Genetic Counseling. Aug, 2020 | Pubmed ID: 32227561 Loss-of-function Variants in CTNNA1 Detected on Multigene Panel Testing in Individuals with Gastric or Breast Cancer Genetics in Medicine : Official Journal of the American College of Medical Genetics. May, 2020 | Pubmed ID: 32051609 Outcomes of Patients with Submucosal (T1b) Esophageal Adenocarcinoma: a Multicenter Cohort Study Gastrointestinal Endoscopy. Jul, 2020 | Pubmed ID: 31953189 Mutant P53 on the Path to Metastasis Trends in Cancer. Jan, 2020 | Pubmed ID: 31952783 Endoscopic Ultrasound Has Limited Utility in Diagnosis of Gastric Cancer in Carriers of CDH1 Mutations Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Feb, 2020 | Pubmed ID: 31077828 Use of HPSC-derived 3D Organoids and Mouse Genetics to Define the Roles of YAP in the Development of the Esophagus Development (Cambridge, England). Dec, 2019 | Pubmed ID: 31748205 Mechanisms Underlying Metastatic Pancreatic Cancer Advances in Experimental Medicine and Biology. 2019 | Pubmed ID: 31576536 Interplay Between Notch1 and Notch3 Promotes EMT and Tumor Initiation in Squamous Cell Carcinoma Nature Communications. Nov, 2017 | Pubmed ID: 29170450 A Summary of the 2016 James W. Freston Conference of the American Gastroenterological Association: Intestinal Metaplasia in the Esophagus and Stomach: Origins, Differences, Similarities and Significance Gastroenterology. Jul, 2017 | Pubmed ID: 28583825 Long-lived Keratin 15+ Esophageal Progenitor Cells Contribute to Homeostasis and Regeneration The Journal of Clinical Investigation. Jun, 2017 | Pubmed ID: 28481227 Gastrin Stimulates a Cholecystokinin-2-receptor-expressing Cardia Progenitor Cell and Promotes Progression of Barrett's-like Esophagus Oncotarget. Jan, 2017 | Pubmed ID: 27448962 Dclk1 Defines Quiescent Pancreatic Progenitors That Promote Injury-Induced Regeneration and Tumorigenesis Cell Stem Cell. Apr, 2016 | Pubmed ID: 27058937 Our New President-Timothy C. Wang, MD Gastroenterology. May, 2016 | Pubmed ID: 27018487 Immature Myeloid Progenitors Promote Disease Progression in a Mouse Model of Barrett's-like Metaplasia Oncotarget. Oct, 2015 | Pubmed ID: 26460825 Multiple Gastrointestinal Polyps in Patients Treated with BRAF Inhibitors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2015 | Pubmed ID: 26202952 Imaging of Secreted Extracellular Periostin, an Important Marker of Invasion in the Tumor Microenvironment in Esophageal Cancer Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Aug, 2015 | Pubmed ID: 26069303 Krt19(+)/Lgr5(-) Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine Cell Stem Cell. Jun, 2015 | Pubmed ID: 26046762 Radiofrequency Ablation Is Associated With Decreased Neoplastic Progression in Patients With Barrett's Esophagus and Confirmed Low-Grade Dysplasia Gastroenterology. Sep, 2015 | Pubmed ID: 25917785 Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential Cell. Jan, 2015 | Pubmed ID: 25594183 Inhibition of Notch Signaling Enhances Transdifferentiation of the Esophageal Squamous Epithelium Towards a Barrett's-like Metaplasia Via KLF4 Cell Cycle (Georgetown, Tex.). 2014 | Pubmed ID: 25558829 Fluorescent Nanoparticle Imaging Allows Noninvasive Evaluation of Immune Cell Modulation in Esophageal Dysplasia Molecular Imaging. 2014 | Pubmed ID: 24824854 Barrett's Esophagus Translational Research Network (BETRNet): the Pivotal Role of Multi-institutional Collaboration in Esophageal Adenocarcinoma Research Gastroenterology. Jun, 2014 | Pubmed ID: 24768332 Recurrence of Esophageal Intestinal Metaplasia After Endoscopic Mucosal Resection and Radiofrequency Ablation of Barrett's Esophagus: Results From a US Multicenter Consortium Gastroenterology. Jul, 2013 | Pubmed ID: 23499759 Optical Imaging of Periostin Enables Early Endoscopic Detection and Characterization of Esophageal Cancer in Mice Gastroenterology. Feb, 2013 | Pubmed ID: 23085486 Bile Acid and Inflammation Activate Gastric Cardia Stem Cells in a Mouse Model of Barrett-like Metaplasia Cancer Cell. Jan, 2012 | Pubmed ID: 22264787 Systemic Activation of K-ras Rapidly Induces Gastric Hyperplasia and Metaplasia in Mice American Journal of Cancer Research. Apr, 2011 | Pubmed ID: 21761008 K-ras Mutation Targeted to Gastric Tissue Progenitor Cells Results in Chronic Inflammation, an Altered Microenvironment, and Progression to Intraepithelial Neoplasia Cancer Research. Nov, 2010 | Pubmed ID: 20959488 Identification of a Bone Marrow-derived Mesenchymal Progenitor Cell Subset That Can Contribute to the Gastric Epithelium Laboratory Investigation; a Journal of Technical Methods and Pathology. Dec, 2009 | Pubmed ID: 19841619 3 डी ऑर्गेनोइड्स में ओरल-एसोफैगल स्क्वैमस सेल कार्सिनोमा मॉडलिंग Samuel Flashner*1, Cecilia Martin*1,2, Norihiro Matsuura1, Masataka Shimonosono1, Yasuto Tomita1, Masaki Morimoto1, Ogoegbunam Okolo1, Victoria X. Yu1,3, Anuraag S. Parikh1,3, Andres J. P. Klein-Szanto4, Kelley Yan1,2, Joel T. Gabre1,5, Chao Lu1,6, Fatemeh Momen-Heravi1,7, Anil K. Rustgi1,5, Hiroshi Nakagawa1,2,5 1Herbert Irving Comprehensive Cancer Center, Columbia University, 2Organoid and Cell Culture Core, Columbia University Digestive and Liver Diseases Research Center, Columbia University, 3Department of Otolaryngology, Head and Neck Surgery, Columbia University, 4Histopathology Facility, Fox Chase Cancer Center, 5Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, 6Department of Genetics and Development, Columbia University, 7Section of Oral, Diagnostic and Rehabilitation Sciences, College of Dental Medicine, Columbia University JoVE 64676 Cancer Research
3 डी ऑर्गेनोइड्स में ओरल-एसोफैगल स्क्वैमस सेल कार्सिनोमा मॉडलिंग Samuel Flashner*1, Cecilia Martin*1,2, Norihiro Matsuura1, Masataka Shimonosono1, Yasuto Tomita1, Masaki Morimoto1, Ogoegbunam Okolo1, Victoria X. Yu1,3, Anuraag S. Parikh1,3, Andres J. P. Klein-Szanto4, Kelley Yan1,2, Joel T. Gabre1,5, Chao Lu1,6, Fatemeh Momen-Heravi1,7, Anil K. Rustgi1,5, Hiroshi Nakagawa1,2,5 1Herbert Irving Comprehensive Cancer Center, Columbia University, 2Organoid and Cell Culture Core, Columbia University Digestive and Liver Diseases Research Center, Columbia University, 3Department of Otolaryngology, Head and Neck Surgery, Columbia University, 4Histopathology Facility, Fox Chase Cancer Center, 5Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, 6Department of Genetics and Development, Columbia University, 7Section of Oral, Diagnostic and Rehabilitation Sciences, College of Dental Medicine, Columbia University JoVE 64676 Cancer Research