C. Ryan Miller Lineberger Comprehensive Cancer Center University of North Carolina School of Medicine Biography Publications Institution JoVE Articles C. Ryan Miller has not added a biography. If you are C. Ryan Miller and would like to personalize this page please email our Author Liaison for assistance. Publications ClearCode34: A Prognostic Risk Predictor for Localized Clear Cell Renal Cell Carcinoma European Urology. Jul, 2014 | Pubmed ID: 24613583 Erythropoietin Promotes Breast Tumorigenesis Through Tumor-initiating Cell Self-renewal The Journal of Clinical Investigation. Feb, 2014 | Pubmed ID: 24435044 Development of DNA Damage Response Signaling Biomarkers Using Automated, Quantitative Image Analysis The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Mar, 2014 | Pubmed ID: 24309508 Where Are We Now? And Where Are We Going? A Report from the Accelerate Brain Cancer Cure (ABC2) Low-grade Glioma Research Workshop Neuro-oncology. Jan, 2014 | Pubmed ID: 24305708 αB-crystallin: a Novel Regulator of Breast Cancer Metastasis to the Brain Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2014 | Pubmed ID: 24132917 The Role of Ect2 Nuclear RhoGEF Activity in Ovarian Cancer Cell Transformation Genes & Cancer. Nov, 2013 | Pubmed ID: 24386507 Hexokinase-2-mediated Aerobic Glycolysis is Integral to Cerebellar Neurogenesis and Pathogenesis of Medulloblastoma Cancer & Metabolism. 2013 | Pubmed ID: 24280485 Cerebellar Granule Neuron Progenitors Are the Source of Hk2 in the Postnatal Cerebellum Cancer & Metabolism. 2013 | Pubmed ID: 24280296 Evolutionary Etiology of High-grade Astrocytomas Proceedings of the National Academy of Sciences of the United States of America. Oct, 2013 | Pubmed ID: 24114272 Hexokinase-2-mediated Aerobic Glycolysis is Integral to Cerebellar Neurogenesis and Pathogenesis of Medulloblastoma Cancer & Metabolism. Jan, 2013 | Pubmed ID: 24078863 Tumor-infiltrating Lymphocytes in Glioblastoma Are Associated with Specific Genomic Alterations and Related to Transcriptional Class Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2013 | Pubmed ID: 23864165 Cooperativity Between MAPK and PI3K Signaling Activation is Required for Glioblastoma Pathogenesis Neuro-oncology. Oct, 2013 | Pubmed ID: 23814263 Prediction of Lung Cancer Histological Types by RT-qPCR Gene Expression in FFPE Specimens The Journal of Molecular Diagnostics : JMD. Jul, 2013 | Pubmed ID: 23701907 Pharmacokinetics and Efficacy of PEGylated Liposomal Doxorubicin in an Intracranial Model of Breast Cancer PloS One. 2013 | Pubmed ID: 23650496 MERTK Receptor Tyrosine Kinase is a Therapeutic Target in Melanoma The Journal of Clinical Investigation. May, 2013 | Pubmed ID: 23585477 HIF1α and HIF2α Independently Activate SRC to Promote Melanoma Metastases The Journal of Clinical Investigation. May, 2013 | Pubmed ID: 23563312 Histological Predictors of Outcome in Ependymoma Are Dependent on Anatomic Site Within the Central Nervous System Brain Pathology (Zurich, Switzerland). Sep, 2013 | Pubmed ID: 23452038 Genome-wide Profiles of CtBP Link Metabolism with Genome Stability and Epithelial Reprogramming in Breast Cancer Nature Communications. 2013 | Pubmed ID: 23385593 Diagnostic Utility of Major Basic Protein, Eotaxin-3, and Leukotriene Enzyme Staining in Eosinophilic Esophagitis The American Journal of Gastroenterology. Oct, 2012 | Pubmed ID: 22777338 LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma Cancer Cell. Jun, 2012 | Pubmed ID: 22698401 Differential Pathogenesis of Lung Adenocarcinoma Subtypes Involving Sequence Mutations, Copy Number, Chromosomal Instability, and Methylation PloS One. 2012 | Pubmed ID: 22590557 Validation of Interobserver Agreement in Lung Cancer Assessment Hematoxylin-Eosin Diagnostic Reproducibility for Non-Small Cell Lung Cancer-The 2004 World Health Organization Classification and Therapeutically Relevant Subsets Archives of Pathology & Laboratory Medicine. May, 2012 | Pubmed ID: 22583114 An Animal Model of MYC-driven Medulloblastoma Cancer Cell. Feb, 2012 | Pubmed ID: 22340590 Genetically Engineered Mouse Models of Diffuse Gliomas Brain Research Bulletin. May, 2012 | Pubmed ID: 21684324 RhoGDI2 Antagonizes Ovarian Carcinoma Growth, Invasion and Metastasis Small GTPases. 7, 2011 | Pubmed ID: 22145092 Phosphatidylinositol 3-kinase Pathway Activation in Breast Cancer Brain Metastases Breast Cancer Research : BCR. 2011 | Pubmed ID: 22132754 High XRCC1 Protein Expression is Associated with Poorer Survival in Patients with Head and Neck Squamous Cell Carcinoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2011 | Pubmed ID: 21908577 The Prognostic Contribution of Clinical Breast Cancer Subtype, Age, and Race Among Patients with Breast Cancer Brain Metastases Cancer. Apr, 2011 | Pubmed ID: 21472708 Gone FISHing: Clinical Lessons Learned in Brain Tumor Molecular Diagnostics over the Last Decade Brain Pathology (Zurich, Switzerland). Jan, 2011 | Pubmed ID: 21129060 Tryptase Staining of Mast Cells May Differentiate Eosinophilic Esophagitis from Gastroesophageal Reflux Disease The American Journal of Gastroenterology. Feb, 2011 | Pubmed ID: 20978486 Lung Squamous Cell Carcinoma MRNA Expression Subtypes Are Reproducible, Clinically Important, and Correspond to Normal Cell Types Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2010 | Pubmed ID: 20643781 Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1 Cancer Cell. Jan, 2010 | Pubmed ID: 20129251 Risk of Recurrence of Resected Stage I Non-small Cell Lung Cancer in Elderly Patients As Compared with Younger Patients Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Nov, 2009 | Pubmed ID: 19692932 Malignant Gliomas with Primitive Neuroectodermal Tumor-like Components: a Clinicopathologic and Genetic Study of 53 Cases Brain Pathology (Zurich, Switzerland). Jan, 2009 | Pubmed ID: 18452568 A Clinical Model to Estimate Recurrence Risk in Resected Stage I Non-small Cell Lung Cancer American Journal of Clinical Oncology. Feb, 2008 | Pubmed ID: 18376223 Glioblastoma Archives of Pathology & Laboratory Medicine. Mar, 2007 | Pubmed ID: 17516742 Pharmacogenomics of Cancer Chemotherapy-induced Toxicity The Journal of Supportive Oncology. Jan, 2007 | Pubmed ID: 17265780 Significance of Necrosis in Grading of Oligodendroglial Neoplasms: a Clinicopathologic and Genetic Study of Newly Diagnosed High-grade Gliomas Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2006 | Pubmed ID: 17135643 Delta24-hyCD Adenovirus Suppresses Glioma Growth in Vivo by Combining Oncolysis and Chemosensitization Cancer Gene Therapy. Mar, 2005 | Pubmed ID: 15650766 Induction of Thymidine Phosphorylase in Both Irradiated and Shielded, Contralateral Human U87MG Glioma Xenografts: Implications for a Dual Modality Treatment Using Capecitabine and Irradiation Molecular Cancer Therapeutics. Oct, 2002 | Pubmed ID: 12481438 Intratumoral 5-fluorouracil Produced by Cytosine Deaminase/5-fluorocytosine Gene Therapy is Effective for Experimental Human Glioblastomas Cancer Research. Feb, 2002 | Pubmed ID: 11830532 Quantitation of Cytosine Deaminase MRNA by Real-time Reverse Transcription Polymerase Chain Reaction: a Sensitive Method for Assessing 5-fluorocytosine Toxicity in Vitro Analytical Biochemistry. Feb, 2002 | Pubmed ID: 11814289 Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice Robert S. McNeill1, Ralf S. Schmid2, Ryan E. Bash3, Mark Vitucci4, Kristen K. White1, Andrea M. Werneke3, Brian H. Constance5, Byron Huff6, C. Ryan Miller2,3,7 1Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, 2Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, 3Division of Neuropathology, Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, 4Curriculum in Genetics and Molecular Biology, University of North Carolina School of Medicine, 5Biological and Biomedical Sciences Program, University of North Carolina School of Medicine, 6Department of Radiation Oncology, Emory University School of Medicine, 7Department of Neurology, Neurosciences Center, University of North Carolina School of Medicine JoVE 51763 Neuroscience
Modeling Astrocytoma Pathogenesis In Vitro and In Vivo Using Cortical Astrocytes or Neural Stem Cells from Conditional, Genetically Engineered Mice Robert S. McNeill1, Ralf S. Schmid2, Ryan E. Bash3, Mark Vitucci4, Kristen K. White1, Andrea M. Werneke3, Brian H. Constance5, Byron Huff6, C. Ryan Miller2,3,7 1Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, 2Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, 3Division of Neuropathology, Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, 4Curriculum in Genetics and Molecular Biology, University of North Carolina School of Medicine, 5Biological and Biomedical Sciences Program, University of North Carolina School of Medicine, 6Department of Radiation Oncology, Emory University School of Medicine, 7Department of Neurology, Neurosciences Center, University of North Carolina School of Medicine JoVE 51763 Neuroscience