Carole L. Yauk Environmental Health Science and Research Bureau Health Canada Biography Publications Institution JoVE Articles Carole L. Yauk has not added a biography. If you are Carole L. Yauk and would like to personalize this page please email our Author Liaison for assistance. Publications Identification of Mechanisms of Action of Bisphenol A-induced Human Preadipocyte Differentiation by Transcriptional Profiling Obesity (Silver Spring, Md.). Jul, 2014 | Pubmed ID: 25047013 Thyroid Hormone Response Element Half-site Organization and Its Effect on Thyroid Hormone Mediated Transcription PloS One. 2014 | Pubmed ID: 24971931 Particle-induced Pulmonary Acute Phase Response May Be the Causal Link Between Particle Inhalation and Cardiovascular Disease Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. Jun, 2014 | Pubmed ID: 24920450 Bromodeoxyuridine (BrdU) Treatment to Measure Hepatocellular Proliferation Does Not Mask Furan-induced Gene Expression Changes in Mouse Liver Toxicology. Sep, 2014 | Pubmed ID: 24910943 Transient Maternal Hypothyroxinemia Potentiates the Transcriptional Response to Exogenous Thyroid Hormone in the Fetal Cerebral Cortex Before the Onset of Fetal Thyroid Function: A Messenger and MicroRNA Profiling Study Cerebral Cortex (New York, N.Y. : 1991). Feb, 2014 | Pubmed ID: 24436321 Tris(1,3-dichloro-2-propyl) Phosphate Perturbs the Expression of Genes Involved in Immune Response and Lipid and Steroid Metabolism in Chicken Embryos Toxicology and Applied Pharmacology. Mar, 2014 | Pubmed ID: 24407104 Case Study on the Utility of Hepatic Global Gene Expression Profiling in the Risk Assessment of the Carcinogen Furan Toxicology and Applied Pharmacology. Jan, 2014 | Pubmed ID: 24183702 Transcriptomic Analysis Reveals Novel Mechanistic Insight into Murine Biological Responses to Multi-walled Carbon Nanotubes in Lungs and Cultured Lung Epithelial Cells PloS One. 2013 | Pubmed ID: 24260392 Carbon Black Nanoparticle Intratracheal Instillation Does Not Alter Cardiac Gene Expression Cardiovascular Toxicology. Dec, 2013 | Pubmed ID: 24078381 Incorporating New Technologies into Toxicity Testing and Risk Assessment: Moving from 21st Century Vision to a Data-driven Framework Toxicological Sciences : an Official Journal of the Society of Toxicology. Nov, 2013 | Pubmed ID: 23958734 In Utero Exposure to Nanosized Carbon Black (Printex90) Does Not Induce Tandem Repeat Mutations in Female Murine Germ Cells Reproductive Toxicology (Elmsford, N.Y.). Nov, 2013 | Pubmed ID: 23871697 Differential Expression of Long Noncoding RNAs in the Livers of Female B6C3F1 Mice Exposed to the Carcinogen Furan Toxicological Sciences : an Official Journal of the Society of Toxicology. Oct, 2013 | Pubmed ID: 23853263 Hepatic Genotoxicity and Toxicogenomic Responses in Muta™Mouse Males Treated with Dibenz[a,h]anthracene Mutagenesis. Sep, 2013 | Pubmed ID: 23793610 Toxicogenomic Outcomes Predictive of Forestomach Carcinogenesis Following Exposure to Benzo(a)pyrene: Relevance to Human Cancer Risk Toxicology and Applied Pharmacology. Dec, 2013 | Pubmed ID: 23735875 Identification of Thyroid Hormone Receptor Binding Sites in Developing Mouse Cerebellum BMC Genomics. 2013 | Pubmed ID: 23701648 In Vitro Microarray Analysis Identifies Genes in Acute-phase Response Pathways That Are Down-regulated in the Liver of Chicken Embryos Exposed in Ovo to PFUdA Toxicology in Vitro : an International Journal Published in Association with BIBRA. Sep, 2013 | Pubmed ID: 23602845 Pulmonary Instillation of Low Doses of Titanium Dioxide Nanoparticles in Mice Leads to Particle Retention and Gene Expression Changes in the Absence of Inflammation Toxicology and Applied Pharmacology. Jun, 2013 | Pubmed ID: 23557971 A Global Toxicogenomic Analysis Investigating the Mechanistic Differences Between Tobacco and Marijuana Smoke Condensates in Vitro Toxicology. Jun, 2013 | Pubmed ID: 23542559 Mice Exposed in Situ to Urban Air Pollution Exhibit Pulmonary Alterations in Gene Expression in the Lipid Droplet Synthesis Pathways Environmental and Molecular Mutagenesis. May, 2013 | Pubmed ID: 23536514 No Evidence for Transgenerational Genomic Instability in the F1 or F2 Descendants of Muta™Mouse Males Exposed to N-ethyl-N-nitrosourea Mutation Research. Jan-Feb, 2013 | Pubmed ID: 23499255 Preparation of Archival Formalin-fixed Paraffin-embedded Mouse Liver Samples for Use with the Agilent Gene Expression Microarray Platform Journal of Pharmacological and Toxicological Methods. Sep-Oct, 2013 | Pubmed ID: 23458726 Building on the Past, Shaping the Future: the Environmental Mutagenesis and Genomics Society Environmental and Molecular Mutagenesis. Apr, 2013 | Pubmed ID: 23444128 IL-1 Receptor Regulates MicroRNA-135b Expression in a Negative Feedback Mechanism During Cigarette Smoke-induced Inflammation Journal of Immunology (Baltimore, Md. : 1950). Apr, 2013 | Pubmed ID: 23440414 The Development of Adverse Outcome Pathways for Mutagenic Effects for the Organization for Economic Co-operation and Development Environmental and Molecular Mutagenesis. Mar, 2013 | Pubmed ID: 23355186 Gene Expression Profiling to Identify Potentially Relevant Disease Outcomes and Support Human Health Risk Assessment for Carbon Black Nanoparticle Exposure Toxicology. Jan, 2013 | Pubmed ID: 23146762 Investigating the Effects of Dietary Folic Acid on Sperm Count, DNA Damage and Mutation in Balb/c Mice Mutation Research. Sep, 2012 | Pubmed ID: 22824165 Transcriptional Profiles in the Cerebral Hemisphere of Chicken Embryos Following in Ovo Perfluorohexane Sulfonate Exposure Toxicological Sciences : an Official Journal of the Society of Toxicology. Oct, 2012 | Pubmed ID: 22790973 Carbon Black Nanoparticle Intratracheal Installation Results in Large and Sustained Changes in the Expression of MiR-135b in Mouse Lung Environmental and Molecular Mutagenesis. Jul, 2012 | Pubmed ID: 22753103 NanoTIO(2) (UV-Titan) Does Not Induce ESTR Mutations in the Germline of Prenatally Exposed Female Mice Particle and Fibre Toxicology. 2012 | Pubmed ID: 22656316 Hepatic and Pulmonary Toxicogenomic Profiles in Mice Intratracheally Instilled with Carbon Black Nanoparticles Reveal Pulmonary Inflammation, Acute Phase Response, and Alterations in Lipid Homeostasis Toxicological Sciences : an Official Journal of the Society of Toxicology. Jun, 2012 | Pubmed ID: 22461453 Supplemental Dietary Folic Acid Has No Effect on Chromosome Damage in Erythrocyte Progenitor Cells of Mice The Journal of Nutrition. May, 2012 | Pubmed ID: 22437555 Genetic Toxicology and Toxicogenomic Analysis of Three Cigarette Smoke Condensates in Vitro Reveals Few Differences Among Full-flavor, Blonde, and Light Products Environmental and Molecular Mutagenesis. May, 2012 | Pubmed ID: 22431010 Overexpression of Tumor Necrosis Factor-α in the Lungs Alters Immune Response, Matrix Remodeling, and Repair and Maintenance Pathways The American Journal of Pathology. Apr, 2012 | Pubmed ID: 22322299 Carbon Black Nanoparticle Instillation Induces Sustained Inflammation and Genotoxicity in Mouse Lung and Liver Particle and Fibre Toxicology. 2012 | Pubmed ID: 22300514 Hepatic MRNA, MicroRNA, and MiR-34a-target Responses in Mice After 28 Days Exposure to Doses of Benzo(a)pyrene That Elicit DNA Damage and Mutation Environmental and Molecular Mutagenesis. Jan, 2012 | Pubmed ID: 21964900 Thyroid Hormone-regulated Gene Expression in Juvenile Mouse Liver: Identification of Thyroid Response Elements Using Microarray Profiling and in Silico Analyses BMC Genomics. 2011 | Pubmed ID: 22206413 Barhl1 is Directly Regulated by Thyroid Hormone in the Developing Cerebellum of Mice Biochemical and Biophysical Research Communications. Nov, 2011 | Pubmed ID: 22027146 Exposure of Pregnant Mice to Carbon Black by Intratracheal Instillation: Toxicogenomic Effects in Dams and Offspring Mutation Research. Oct, 2011 | Pubmed ID: 22001195 Technical-grade Perfluorooctane Sulfonate Alters the Expression of More Transcripts in Cultured Chicken Embryonic Hepatocytes Than Linear Perfluorooctane Sulfonate Environmental Toxicology and Chemistry / SETAC. Dec, 2011 | Pubmed ID: 21994020 Sidestream Tobacco Smoke is a Male Germ Cell Mutagen Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21768363 Germline Mutation Rates in Mice Following in Utero Exposure to Diesel Exhaust Particles by Maternal Inhalation Mutation Research. Jul, 2011 | Pubmed ID: 21570989 Assessment of Subclinical, Toxicant-induced Hepatic Gene Expression Profiles After Low-dose, Short-term Exposures in Mice Regulatory Toxicology and Pharmacology : RTP. Jun, 2011 | Pubmed ID: 21335049 Pulmonary Response to Surface-coated Nanotitanium Dioxide Particles Includes Induction of Acute Phase Response Genes, Inflammatory Cascades, and Changes in MicroRNAs: a Toxicogenomic Study Environmental and Molecular Mutagenesis. Jul, 2011 | Pubmed ID: 21259345 Germ Cell Mutagens: Risk Assessment Challenges in the 21st Century Environmental and Molecular Mutagenesis. Oct-Dec, 2010 | Pubmed ID: 20740630 Acetaminophen Modulates the Transcriptional Response to Recombinant Interferon-beta PloS One. 2010 | Pubmed ID: 20544007 Cross-platform Analysis of Global MicroRNA Expression Technologies BMC Genomics. 2010 | Pubmed ID: 20504329 Induction of the Interleukin 6/ Signal Transducer and Activator of Transcription Pathway in the Lungs of Mice Sub-chronically Exposed to Mainstream Tobacco Smoke BMC Medical Genomics. 2009 | Pubmed ID: 19698101 Impact of Nose-only Exposure System on Pulmonary Gene Expression Inhalation Toxicology. Jul, 2009 | Pubmed ID: 19558237 Toxicogenomic Analysis of Susceptibility to Inhaled Urban Particulate Matter in Mice with Chronic Lung Inflammation Particle and Fibre Toxicology. 2009 | Pubmed ID: 19284582 Identification of Thyroid Hormone Receptor Binding Sites and Target Genes Using ChIP-on-chip in Developing Mouse Cerebellum PloS One. 2009 | Pubmed ID: 19240802 Toxicogenomic Analysis of Mainstream Tobacco Smoke-exposed Mice Reveals Repression of Plasminogen Activator Inhibitor-1 Gene in Heart Inhalation Toxicology. Jan, 2009 | Pubmed ID: 18925475 Tandem Repeat Mutation, Global DNA Methylation, and Regulation of DNA Methyltransferases in Cultured Mouse Embryonic Fibroblast Cells Chronically Exposed to Chemicals with Different Modes of Action Environmental and Molecular Mutagenesis. Jan, 2008 | Pubmed ID: 18172875 Analysis of Gene Expression in Two Human-derived Cell Lines Exposed in Vitro to a 1.9 GHz Pulse-modulated Radiofrequency Field Proteomics. Nov, 2007 | Pubmed ID: 17902192 Mainstream Tobacco Smoke Causes Paternal Germ-line DNA Mutation Cancer Research. Jun, 2007 | Pubmed ID: 17545587 Hepatic Gene Expression Changes in Hypothyroid Juvenile Mice: Characterization of a Novel Negative Thyroid-responsive Element Endocrinology. Aug, 2007 | Pubmed ID: 17463053 Review of the Literature Examining the Correlation Among DNA Microarray Technologies Environmental and Molecular Mutagenesis. Jun, 2007 | Pubmed ID: 17370338 Novel Design and Controls for Focused DNA Microarrays: Applications in Quality Assurance/control and Normalization for the Health Canada ToxArray BMC Genomics. 2006 | Pubmed ID: 17052352 Detection of Induced Male Germline Mutation: Correlations and Comparisons Between Traditional Germline Mutation Assays, Transgenic Rodent Assays and Expanded Simple Tandem Repeat Instability Assays Mutation Research. Jun, 2006 | Pubmed ID: 16542687 Instability of Expanded Simple Tandem Repeats is Induced in Cell Culture by a Variety of Agents: N-Nitroso-N-ethylurea, Benzo(a)pyrene, Etoposide and Okadaic Acid Mutation Research. Jun, 2006 | Pubmed ID: 16516931 A LacZ Transgenic Mouse Assay for the Detection of Mutations in Follicular Granulosa Cells Mutation Research. Oct, 2005 | Pubmed ID: 16039675 Comprehensive Comparison of Six Microarray Technologies Nucleic Acids Research. 2004 | Pubmed ID: 15333675 Advances in the Application of Germline Tandem Repeat Instability for in Situ Monitoring Mutation Research. Mar, 2004 | Pubmed ID: 15164979 Air Pollution Induces Heritable DNA Mutations Proceedings of the National Academy of Sciences of the United States of America. Dec, 2002 | Pubmed ID: 12473746 A Novel Single Molecule Analysis of Spontaneous and Radiation-induced Mutation at a Mouse Tandem Repeat Locus Mutation Research. Mar, 2002 | Pubmed ID: 11890944 HPLC Måling av DNA Oksidasjon Biomarker, 8-okso-7,8-dihydro-2'-deoksyguanosin, i dyrkede celler og dyrevev Nikolai L. Chepelev1, Dean A. Kennedy1, Remi Gagné1, Taryn White1, Alexandra S. Long1, Carole L. Yauk1, Paul A. White1 1Environmental Health Science and Research Bureau, Health Canada JoVE 52697 Chemistry Transgen Gnagere analyse for Kvantifisering Mann Germ Cell Mutant Frequency Jason M. O'Brien1, Marc A. Beal1, John D. Gingerich1, Lynda Soper1, George R. Douglas1, Carole L. Yauk1, Francesco Marchetti1 1Environmental Health Science and Research Bureau, Health Canada, Environmental Health Centre Biology
HPLC Måling av DNA Oksidasjon Biomarker, 8-okso-7,8-dihydro-2'-deoksyguanosin, i dyrkede celler og dyrevev Nikolai L. Chepelev1, Dean A. Kennedy1, Remi Gagné1, Taryn White1, Alexandra S. Long1, Carole L. Yauk1, Paul A. White1 1Environmental Health Science and Research Bureau, Health Canada JoVE 52697 Chemistry
Transgen Gnagere analyse for Kvantifisering Mann Germ Cell Mutant Frequency Jason M. O'Brien1, Marc A. Beal1, John D. Gingerich1, Lynda Soper1, George R. Douglas1, Carole L. Yauk1, Francesco Marchetti1 1Environmental Health Science and Research Bureau, Health Canada, Environmental Health Centre Biology