Cedric Le May l'Institut du Thorax INSERM, CNRS, UNIV Nantes Biography Publications Institution JoVE Articles Cedric Le May has not added a biography. If you are Cedric Le May and would like to personalize this page please email our Author Liaison for assistance. Publications The SGLT2 Inhibitor Dapagliflozin Prevents Cardiomyopathy in a Diabetic Lipodystrophic Mouse Model Diabetes. Jan, 2017 | Pubmed ID: 28052965 Glycaemic Control Influences the Relationship Between Plasma PCSK9 and LDL Cholesterol in Type 1 Diabetes Diabetes, Obesity & Metabolism. Mar, 2017 | Pubmed ID: 27804190 Retrograde Cholesterol Transport in the Human Caco-2/TC7 Cell Line: a Model to Study Trans-intestinal Cholesterol Excretion in Atherogenic and Diabetic Dyslipidemia Acta Diabetologica. Feb, 2017 | Pubmed ID: 27796655 FGF21 Improves the Adipocyte Dysfunction Related to Seipin Deficiency Diabetes. Nov, 2016 | Pubmed ID: 27554469 Urine-sample-derived Human Induced Pluripotent Stem Cells As a Model to Study PCSK9-mediated Autosomal Dominant Hypercholesterolemia Disease Models & Mechanisms. Jan, 2016 | Pubmed ID: 26586530 The Loss-of-function PCSK9 P.R46L Genetic Variant Does Not Alter Glucose Homeostasis Diabetologia. Sep, 2015 | Pubmed ID: 26049403 Letter from Le May and Cariou Regarding Article, "Proprotein Convertase Subtilisin Kexin Type 9 Promotes Intestinal Overproduction of Triglyceride-rich Apolipoprotein B Lipoproteins Through Both Low-density Lipoprotein Receptor-dependent and -independent Mechanisms" Circulation. May, 2015 | Pubmed ID: 25940972 Role of PCSK9 Beyond Liver Involvement Current Opinion in Lipidology. Jun, 2015 | Pubmed ID: 25887680 PCSK9-deficiency Does Not Alter Blood Pressure and Sodium Balance in Mouse Models of Hypertension Atherosclerosis. Mar, 2015 | Pubmed ID: 25621930 [Trans-intestinal Cholesterol Excretion (TICE): a New Route for Cholesterol Excretion] Medecine Sciences : M/S. Oct, 2014 | Pubmed ID: 25311025 Preserved Adrenal Function in Fully PCSK9-deficient Subject International Journal of Cardiology. Sep, 2014 | Pubmed ID: 25062564 Congenital Lipodystrophies and Dyslipidemias Current Atherosclerosis Reports. Sep, 2014 | Pubmed ID: 25047893 Transintestinal Cholesterol Excretion is an Active Metabolic Process Modulated by PCSK9 and Statin Involving ABCB1 Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2013 | Pubmed ID: 23559630 Plasma PCSK9 Concentrations During an Oral Fat Load and After Short Term High-fat, High-fat High-protein and High-fructose Diets Nutrition & Metabolism. Jan, 2013 | Pubmed ID: 23298392 Estrogen Receptor Activation Reduces Lipid Synthesis in Pancreatic Islets and Prevents β Cell Failure in Rodent Models of Type 2 Diabetes The Journal of Clinical Investigation. Aug, 2011 | Pubmed ID: 21747171 Clinical Aspects of PCSK9 Atherosclerosis. Jun, 2011 | Pubmed ID: 21596380 Extranuclear Estrogen Receptor-alpha Stimulates NeuroD1 Binding to the Insulin Promoter and Favors Insulin Synthesis Proceedings of the National Academy of Sciences of the United States of America. Jul, 2010 | Pubmed ID: 20616010 Association Between Plasma PCSK9 and Gamma-glutamyl Transferase Levels in Diabetic Patients Atherosclerosis. Aug, 2010 | Pubmed ID: 20452593 PCSK9 is Expressed in Pancreatic Delta-cells and Does Not Alter Insulin Secretion Biochemical and Biophysical Research Communications. Dec, 2009 | Pubmed ID: 19878649 PCSK9 Dominant Negative Mutant Results in Increased LDL Catabolic Rate and Familial Hypobetalipoproteinemia Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2009 | Pubmed ID: 19762784 Importance of Extranuclear Estrogen Receptor-alpha and Membrane G Protein-coupled Estrogen Receptor in Pancreatic Islet Survival Diabetes. Oct, 2009 | Pubmed ID: 19587358 Proprotein Convertase Subtilisin Kexin Type 9 Null Mice Are Protected from Postprandial Triglyceridemia Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2009 | Pubmed ID: 19265033 Involvement of ZIP/p62 in the Regulation of PPARalpha Transcriptional Activity by P38-MAPK Biochimica Et Biophysica Acta. May, 2008 | Pubmed ID: 18374665 Activation of the Farnesoid X Receptor Represses PCSK9 Expression in Human Hepatocytes FEBS Letters. Mar, 2008 | Pubmed ID: 18298956 Dual Mechanisms for the Fibrate-mediated Repression of Proprotein Convertase Subtilisin/kexin Type 9 The Journal of Biological Chemistry. Apr, 2008 | Pubmed ID: 18245819 Estrogens Protect Pancreatic Beta-cells from Apoptosis and Prevent Insulin-deficient Diabetes Mellitus in Mice Proceedings of the National Academy of Sciences of the United States of America. Jun, 2006 | Pubmed ID: 16754860 Fatty Acids Induce L-CPT I Gene Expression Through a PPARalpha-independent Mechanism in Rat Hepatoma Cells The Journal of Nutrition. Oct, 2005 | Pubmed ID: 16177188 PAX4 Gene Variations Predispose to Ketosis-prone Diabetes Human Molecular Genetics. Dec, 2004 | Pubmed ID: 15509590 Control of Gene Expression by Fatty Acids The Journal of Nutrition. Sep, 2004 | Pubmed ID: 15333740 Techniken der Schlauchmagen-Operation und Modified Roux-en-Y-Magenbypass bei Mäusen Audrey Ayer1, Frederic Borel1, Francois Moreau1, Xavier Prieur1, Michel Neunlist2, Bertrand Cariou3, Claire Blanchard*1,4, Cedric Le May*1 1l'Institut du Thorax, INSERM, CNRS, UNIV Nantes, 2CHU Nantes, Institut des Maladies de l'Appareil Digestif, INSERM U913, 3l'Institut du Thorax, INSERM, CNRS, UNIV Nantes, CHU Nantes, 4Service de Clinique Chirurgicale Digestive et Endocrinienne, CHU de Nantes Medicine
Techniken der Schlauchmagen-Operation und Modified Roux-en-Y-Magenbypass bei Mäusen Audrey Ayer1, Frederic Borel1, Francois Moreau1, Xavier Prieur1, Michel Neunlist2, Bertrand Cariou3, Claire Blanchard*1,4, Cedric Le May*1 1l'Institut du Thorax, INSERM, CNRS, UNIV Nantes, 2CHU Nantes, Institut des Maladies de l'Appareil Digestif, INSERM U913, 3l'Institut du Thorax, INSERM, CNRS, UNIV Nantes, CHU Nantes, 4Service de Clinique Chirurgicale Digestive et Endocrinienne, CHU de Nantes Medicine