Ching-Kang Chen Department of Ophthalmology Baylor College of Medicine Biography Publications Institution JoVE Articles Ching-Kang Chen has not added a biography. If you are Ching-Kang Chen and would like to personalize this page please email our Author Liaison for assistance. Publications A Novel Retinal Oscillation Mechanism in an Autosomal Dominant Photoreceptor Degeneration Mouse Model Frontiers in Cellular Neuroscience. 2015 | Pubmed ID: 26793064 RGS Protein Regulation of Phototransduction Progress in Molecular Biology and Translational Science. 2015 | Pubmed ID: 26123301 Rhodopsin Kinase and Recoverin Modulate Phosphodiesterase During Mouse Photoreceptor Light Adaptation The Journal of General Physiology. Mar, 2015 | Pubmed ID: 25667411 Retinal Cone Photoreceptors Require Phosducin-like Protein 1 for G Protein Complex Assembly and Signaling PloS One. 2015 | Pubmed ID: 25659125 Cannabinoid Receptor-interacting Protein 1a Modulates CB1 Receptor Signaling and Regulation Molecular Pharmacology. Apr, 2015 | Pubmed ID: 25657338 Visual Defects in a Mouse Model of Fetal Alcohol Spectrum Disorder Frontiers in Pediatrics. 2014 | Pubmed ID: 25346924 G Protein Beta 5 is Targeted to D2-dopamine Receptor-containing Biochemical Compartments and Blocks Dopamine-dependent Receptor Internalization PloS One. 2014 | Pubmed ID: 25162404 Phosducin-like Protein 1 is Essential for G-protein Assembly and Signaling in Retinal Rod Photoreceptors The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2013 | Pubmed ID: 23637185 Light-induced Translocation of RGS9-1 and Gβ5L in Mouse Rod Photoreceptors PloS One. 2013 | Pubmed ID: 23555598 Role of ELOVL4 and Very Long-chain Polyunsaturated Fatty Acids in Mouse Models of Stargardt Type 3 Retinal Degeneration Proceedings of the National Academy of Sciences of the United States of America. Mar, 2013 | Pubmed ID: 23479632 Modulation of Mouse Rod Response Decay by Rhodopsin Kinase and Recoverin The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2012 | Pubmed ID: 23136436 The Relationship Between Slow Photoresponse Recovery Rate and Temporal Resolution of Vision The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2012 | Pubmed ID: 23055507 Defective Retinal Depolarizing Bipolar Cells in Regulators of G Protein Signaling (RGS) 7 and 11 Double Null Mice The Journal of Biological Chemistry. Apr, 2012 | Pubmed ID: 22371490 Modulation of CREB in the Dorsal Lateral Geniculate Nucleus of Dark-reared Mice Neural Plasticity. 2012 | Pubmed ID: 22292123 Knockout of G Protein β5 Impairs Brain Development and Causes Multiple Neurologic Abnormalities in Mice Journal of Neurochemistry. Nov, 2011 | Pubmed ID: 21883221 Nicotinic Excitatory Postsynaptic Potentials in Hippocampal CA1 Interneurons Are Predominantly Mediated by Nicotinic Receptors That Contain α4 and β2 Subunits Neuropharmacology. Dec, 2011 | Pubmed ID: 21878344 Rod Segmento Externo Formación El Retinol Es Independiente De ABCA4, Arrestina, Rodopsina Quinasa, Y Palmitylation Rodopsina Investigative Ophthalmology & Visual Science. May, 2011 | Pubmed ID: 21398289 RGS6, Un Modulador De La Activación Parasimpática En El Corazón Circulation Research. Nov, 2010 | Pubmed ID: 20864673 Deletion of GRK1 Causes Retina Degeneration Through a Transducin-independent Mechanism The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2010 | Pubmed ID: 20164334 Background Light Produces a Recoverin-dependent Modulation of Activated-rhodopsin Lifetime in Mouse Rods The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2010 | Pubmed ID: 20107049 Functional Redundancy of R7 RGS Proteins in ON-bipolar Cell Dendrites Investigative Ophthalmology & Visual Science. Feb, 2010 | Pubmed ID: 19797210 The Role of Gβ5 in Vision Progress in Molecular Biology and Translational Science. 2009 | Pubmed ID: 20374718 Trafficking of Membrane Proteins to Cone but Not Rod Outer Segments is Dependent on Heterotrimeric Kinesin-II The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2009 | Pubmed ID: 19906976 Role of LPA4/p2y9/GPR23 in Negative Regulation of Cell Motility Molecular Biology of the Cell. Dec, 2008 | Pubmed ID: 18843048 Molecular Architecture of Galphao and the Structural Basis for RGS16-mediated Deactivation Proceedings of the National Academy of Sciences of the United States of America. Apr, 2008 | Pubmed ID: 18434540 Esfingosina-1-fosfato Y Endotelina-1 Inducen La Expresión De La Proteína Rgs16 En Miocitos Cardiacos Por Activación Transcripcional Del Gen Rgs16 Naunyn-Schmiedeberg's Archives of Pharmacology. Jan, 2008 | Pubmed ID: 18046543 Gbeta5 is Required for Normal Light Responses and Morphology of Retinal ON-bipolar Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2007 | Pubmed ID: 18094259 Expression and Localization of RGS9-2/G 5/R7BP Complex in Vivo is Set by Dynamic Control of Its Constitutive Degradation by Cellular Cysteine Proteases The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2007 | Pubmed ID: 18094251 Subunit Dissociation and Diffusion Determine the Subcellular Localization of Rod and Cone Transducins The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2007 | Pubmed ID: 17507570 Translocación Transducina En Las Barras Es Provocada Por La Saturación Del Complejo Activador De GTPasa The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2007 | Pubmed ID: 17267570 RGS Expression Rate-limits Recovery of Rod Photoresponses Neuron. Aug, 2006 | Pubmed ID: 16908407 Phototransduction in a Transgenic Mouse Model of Nougaret Night Blindness The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2006 | Pubmed ID: 16793893 GAP-independent Termination of Photoreceptor Light Response by Excess Gamma Subunit of the CGMP-phosphodiesterase The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2006 | Pubmed ID: 16641226 Deactivation of Phosphorylated and Nonphosphorylated Rhodopsin by Arrestin Splice Variants The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2006 | Pubmed ID: 16421323 Transducin Activation State Controls Its Light-dependent Translocation in Rod Photoreceptors The Journal of Biological Chemistry. Dec, 2005 | Pubmed ID: 16207703 D2 Dopamine Receptors Colocalize Regulator of G-protein Signaling 9-2 (RGS9-2) Via the RGS9 DEP Domain, and RGS9 Knock-out Mice Develop Dyskinesias Associated with Dopamine Pathways The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2005 | Pubmed ID: 15728856 Rhodopsin-iCre Transgenic Mouse Line for Cre-mediated Rod-specific Gene Targeting Genesis (New York, N.Y. : 2000). Feb, 2005 | Pubmed ID: 15682388 Photoreceptor CGMP Phosphodiesterase Delta Subunit (PDEdelta) Functions As a Prenyl-binding Protein The Journal of Biological Chemistry. Jan, 2004 | Pubmed ID: 14561760 El Dominio DEP Determina Orientación Subcelular De La GTPasa Proteína RGS9 in Vivo Activadora The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2003 | Pubmed ID: 14614075 Novel Form of Adaptation in Mouse Retinal Rods Speeds Recovery of Phototransduction The Journal of General Physiology. Dec, 2003 | Pubmed ID: 14610022 Prolonged Photoresponses and Defective Adaptation in Rods of Gbeta5-/- Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2003 | Pubmed ID: 12904457 Retinal Remodeling Triggered by Photoreceptor Degenerations The Journal of Comparative Neurology. Sep, 2003 | Pubmed ID: 12866125 RGS9 Modulates Dopamine Signaling in the Basal Ganglia Neuron. Jun, 2003 | Pubmed ID: 12818179 Light-dependent Redistribution of Visual Arrestins and Transducin Subunits in Mice with Defective Phototransduction Molecular Vision. Jun, 2003 | Pubmed ID: 12802257 Instability of GGL Domain-containing RGS Proteins in Mice Lacking the G Protein Beta-subunit Gbeta5 Proceedings of the National Academy of Sciences of the United States of America. May, 2003 | Pubmed ID: 12738888 Palmitoylation Regulates Regulators of G-protein Signaling (RGS) 16 Function. I. Mutation of Amino-terminal Cysteine Residues on RGS16 Prevents Its Targeting to Lipid Rafts and Palmitoylation of an Internal Cysteine Residue The Journal of Biological Chemistry. May, 2003 | Pubmed ID: 12642593 Recoverin and Rhodopsin Kinase Advances in Experimental Medicine and Biology. 2002 | Pubmed ID: 12596917 Evidence for Two Apoptotic Pathways in Light-induced Retinal Degeneration Nature Genetics. Oct, 2002 | Pubmed ID: 12219089 Patch Clamp grabación de células amacrinas Starburst en un plano de montaje Preparación de Deafferentated retina del ratón Hung-Ya Tu1, Chih-Chun Hsu1,2, Yu-Jiun Chen1, Ching-Kang Chen1,2,3 1Department of Ophthalmology, Baylor College of Medicine, 2Department of Neuroscience, Baylor College of Medicine, 3Department of Biochemistry and Molecular Biology, Baylor College of Medicine JoVE 54608 Neuroscience
Patch Clamp grabación de células amacrinas Starburst en un plano de montaje Preparación de Deafferentated retina del ratón Hung-Ya Tu1, Chih-Chun Hsu1,2, Yu-Jiun Chen1, Ching-Kang Chen1,2,3 1Department of Ophthalmology, Baylor College of Medicine, 2Department of Neuroscience, Baylor College of Medicine, 3Department of Biochemistry and Molecular Biology, Baylor College of Medicine JoVE 54608 Neuroscience