Christine R. Rose Institute of Neurobiology Heinrich Heine University Biography Publications Institution JoVE Articles Christine R. Rose has not added a biography. If you are Christine R. Rose and would like to personalize this page please email our Author Liaison for assistance. Publications Dysregulation of Astrocyte Ion Homeostasis and Its Relevance for Stroke-Induced Brain Damage International Journal of Molecular Sciences. May, 2021 | Pubmed ID: 34073593 Disruption of Glutamate Transport and Homeostasis by Acute Metabolic Stress Frontiers in Cellular Neuroscience. 2021 | Pubmed ID: 33603647 Reactive Astrocyte Nomenclature, Definitions, and Future Directions Nature Neuroscience. 03, 2021 | Pubmed ID: 33589835 AAV-Mediated CRISPRi and RNAi Based Gene Silencing in Mouse Hippocampal Neurons Cells. Feb, 2021 | Pubmed ID: 33557342 Exacerbation of Epilepsy by Astrocyte Alkalization and Gap Junction Uncoupling The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 03, 2021 | Pubmed ID: 33478985 On the Origin of Ultraslow Spontaneous Na Fluctuations in Neurons of the Neonatal Forebrain Journal of Neurophysiology. 02, 2021 | Pubmed ID: 33236936 Local Postsynaptic Signaling on Slow Time Scales in Reciprocal Olfactory Bulb Granule Cell Spines Matches Asynchronous Release Frontiers in Synaptic Neuroscience. 2020 | Pubmed ID: 33304264 Correction: Felix, L.; Ziemens, D.; Seifert, G.; Rose, C.R. Spontaneous Ultraslow Na Fluctuations in the Neonatal Mouse Brain. 2020, , 102 Cells. Oct, 2020 | Pubmed ID: 33143391 Altered Gap Junction Network Topography in Mouse Models for Human Hereditary Deafness International Journal of Molecular Sciences. Oct, 2020 | Pubmed ID: 33036242 Sodium Fluctuations in Astroglia and Their Potential Impact on Astrocyte Function Frontiers in Physiology. 2020 | Pubmed ID: 32903427 Rebuttal from Nanna MacAulay and Christine R. Rose The Journal of Physiology. 11, 2020 | Pubmed ID: 32870504 Astrocytes of the Early Postnatal Brain The European Journal of Neuroscience. May, 2020 | Pubmed ID: 32406559 Quantitative Imaging of Changes in Astrocytic and Neuronal Adenosine Triphosphate Using Two Different Variants of ATeam Frontiers in Cellular Neuroscience. 2020 | Pubmed ID: 32372916 On the Special Role of NCX in Astrocytes: Translating Na-transients into Intracellular Ca Signals Cell Calcium. 03, 2020 | Pubmed ID: 31901681 Na-dependent Transporters: The Backbone of Astroglial Homeostatic Function Cell Calcium. Jan, 2020 | Pubmed ID: 31835178 Bmal1-deficiency Affects Glial Synaptic Coverage of the Hippocampal Mossy Fiber Synapse and the Actin Cytoskeleton in Astrocytes Glia. 05, 2020 | Pubmed ID: 31743496 Spontaneous Ultraslow Na Fluctuations in the Neonatal Mouse Brain Cells. Dec, 2019 | Pubmed ID: 31906100 Quantitative Determination of Cellular [Na] by Fluorescence Lifetime Imaging with CoroNaGreen The Journal of General Physiology. Nov, 2019 | Pubmed ID: 31597684 Relation Between Activity-induced Intracellular Sodium Transients and ATP Dynamics in Mouse Hippocampal Neurons The Journal of Physiology. 12, 2019 | Pubmed ID: 31549401 Heterogeneity of Activity-Induced Sodium Transients Between Astrocytes of the Mouse Hippocampus and Neocortex: Mechanisms and Consequences The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2019 | Pubmed ID: 30737311 Ionic Signalling in Astroglia Beyond Calcium The Journal of Physiology. Feb, 2019 | Pubmed ID: 30734296 Imaging of Local and Global Sodium Signals in Astrocytes Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 30617981 FRET-based Imaging of Intracellular ATP in Organotypic Brain Slices Journal of Neuroscience Research. Aug, 2019 | Pubmed ID: 30506574 Anisotropic Panglial Coupling Reflects Tonotopic Organization in the Inferior Colliculus Frontiers in Cellular Neuroscience. 2018 | Pubmed ID: 30542265 Cotransporter-mediated Water Transport Underlying Cerebrospinal Fluid Formation Nature Communications. 06, 2018 | Pubmed ID: 29867199 Epithelial Sodium Channel Regulates Adult Neural Stem Cell Proliferation in a Flow-Dependent Manner Cell Stem Cell. Jun, 2018 | Pubmed ID: 29779889 Reverse NCX Attenuates Cellular Sodium Loading in Metabolically Compromised Cortex Cerebral Cortex (New York, N.Y. : 1991). 12, 2018 | Pubmed ID: 29136153 Molecular and Cellular Physiology of Sodium-dependent Glutamate Transporters Brain Research Bulletin. 01, 2018 | Pubmed ID: 28040508 Astroglial Glutamate Signaling and Uptake in the Hippocampus Frontiers in Molecular Neuroscience. 2017 | Pubmed ID: 29386994 CD73-derived Adenosine and Tenascin-C Control Cytokine Production by Epicardium-derived Cells Formed After Myocardial Infarction FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2017 | Pubmed ID: 28363952 Astrocyte Sodium Signalling and Panglial Spread of Sodium Signals in Brain White Matter Neurochemical Research. Sep, 2017 | Pubmed ID: 28214986 Differential Effects of Energy Deprivation on Intracellular Sodium Homeostasis in Neurons and Astrocytes Journal of Neuroscience Research. 11, 2017 | Pubmed ID: 28150887 Rapid Sodium Signaling Couples Glutamate Uptake to Breakdown of ATP in Perivascular Astrocyte Endfeet Glia. 02, 2017 | Pubmed ID: 27785828 Changes in the Proliferative Capacity of NG2 Cell Subpopulations During Postnatal Development of the Mouse Hippocampus Brain Structure & Function. 03, 2017 | Pubmed ID: 27306788 Glial Ionic Excitability: The Role for Sodium Glia. 10, 2016 | Pubmed ID: 27509366 Functional Anisotropic Panglial Networks in the Lateral Superior Olive Glia. 11, 2016 | Pubmed ID: 27458984 Extrusion Versus Diffusion: Mechanisms for Recovery from Sodium Loads in Mouse CA1 Pyramidal Neurons The Journal of Physiology. 10, 2016 | Pubmed ID: 27080107 Principles of Sodium Homeostasis and Sodium Signalling in Astroglia Glia. 10, 2016 | Pubmed ID: 26919326 Astrocyte Sodium Signaling and Neuro-metabolic Coupling in the Brain Neuroscience. May, 2016 | Pubmed ID: 25791228 Lactate Rescues Neuronal Sodium Homeostasis During Impaired Energy Metabolism Channels (Austin, Tex.). Jul, 2015 | Pubmed ID: 26039160 Astrocytes Restrict Discharge Duration and Neuronal Sodium Loads During Recurrent Network Activity Glia. Jun, 2015 | Pubmed ID: 25639699 Roles of Astrocytic Na(+),K(+)-ATPase and Glycogenolysis for K(+) Homeostasis in Mammalian Brain Journal of Neuroscience Research. Jul, 2015 | Pubmed ID: 25352321 Dysbalance of Astrocyte Calcium Under Hyperammonemic Conditions PloS One. 2014 | Pubmed ID: 25153709 BDE-47 and 6-OH-BDE-47 Modulate Calcium Homeostasis in Primary Fetal Human Neural Progenitor Cells Via Ryanodine Receptor-independent Mechanisms Archives of Toxicology. Aug, 2014 | Pubmed ID: 24599297 Laminar and Subcellular Heterogeneity of GLAST and GLT-1 Immunoreactivity in the Developing Postnatal Mouse Hippocampus The Journal of Comparative Neurology. Jan, 2014 | Pubmed ID: 23939750 Lesion-induced Alterations in Astrocyte Glutamate Transporter Expression and Function in the Hippocampus ISRN Neurology. 2013 | Pubmed ID: 24078881 Two Sides of the Same Coin: Sodium Homeostasis and Signaling in Astrocytes Under Physiological and Pathophysiological Conditions Glia. Aug, 2013 | Pubmed ID: 23553639 Two-photon Sodium Imaging in Dendritic Spines Cold Spring Harbor Protocols. Nov, 2012 | Pubmed ID: 23118361 Kir4.1 Channels Mediate a Depolarization of Hippocampal Astrocytes Under Hyperammonemic Conditions in Situ Glia. May, 2012 | Pubmed ID: 22431254 Thrombin-induced ATP Release from Human Umbilical Vein Endothelial Cells American Journal of Physiology. Cell Physiology. Mar, 2012 | Pubmed ID: 22159088 Gap Junctions Mediate Intercellular Spread of Sodium Between Hippocampal Astrocytes in Situ Glia. Feb, 2012 | Pubmed ID: 22025386 Astrocyte Calcium Signals at Schaffer Collateral to CA1 Pyramidal Cell Synapses Correlate with the Number of Activated Synapses but Not with Synaptic Strength Hippocampus. Jan, 2012 | Pubmed ID: 20882545 Levetiracetam Exhibits Protective Properties on Rat Schwann Cells in Vitro Journal of the Peripheral Nervous System : JPNS. Sep, 2011 | Pubmed ID: 22003940 Contrasting Macrophage Activation by Fine and Ultrafine Titanium Dioxide Particles is Associated with Different Uptake Mechanisms Particle and Fibre Toxicology. 2011 | Pubmed ID: 21995556 A New Role for Interferon Gamma in Neural Stem/precursor Cell Dysregulation Molecular Neurodegeneration. 2011 | Pubmed ID: 21371330 Ammonium Influx Pathways into Astrocytes and Neurones of Hippocampal Slices Journal of Neurochemistry. Dec, 2010 | Pubmed ID: 20854430 Polybrominated Diphenyl Ethers Induce Developmental Neurotoxicity in a Human in Vitro Model: Evidence for Endocrine Disruption Environmental Health Perspectives. Apr, 2010 | Pubmed ID: 20368126 Ion Changes and Signalling in Perisynaptic Glia Brain Research Reviews. May, 2010 | Pubmed ID: 19895844 Synaptically Induced Sodium Signals in Hippocampal Astrocytes in Situ The Journal of Physiology. Dec, 2009 | Pubmed ID: 19858225 REMOVED: Ion Changes and Signalling in Perisynaptic Glia Brain Research. Oct, 2009 | Pubmed ID: 19835850 Neuron-glia Communication Via EphA4/ephrin-A3 Modulates LTP Through Glial Glutamate Transport Nature Neuroscience. Oct, 2009 | Pubmed ID: 19734893 Ammonium-evoked Alterations in Intracellular Sodium and PH Reduce Glial Glutamate Transport Activity Glia. Jul, 2009 | Pubmed ID: 19053055 Sodium Signals in Cerebellar Purkinje Neurons and Bergmann Glial Cells Evoked by Glutamatergic Synaptic Transmission Glia. Aug, 2008 | Pubmed ID: 18442095 Developmental Profile and Mechanisms of GABA-induced Calcium Signaling in Hippocampal Astrocytes Glia. Aug, 2008 | Pubmed ID: 18442094 Properties of the New Fluorescent Na+ Indicator CoroNa Green: Comparison with SBFI and Confocal Na+ Imaging Journal of Neuroscience Methods. Sep, 2006 | Pubmed ID: 16488020 From Modulator to Mediator: Rapid Effects of BDNF on Ion Channels BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Nov, 2004 | Pubmed ID: 15499580 Truncated TrkB-T1 Mediates Neurotrophin-evoked Calcium Signalling in Glia Cells Nature. Nov, 2003 | Pubmed ID: 14603320 Calbindin in Cerebellar Purkinje Cells is a Critical Determinant of the Precision of Motor Coordination The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2003 | Pubmed ID: 12716955 Functional Reconstitution of Vascular Smooth Muscle Cells with CGMP-dependent Protein Kinase I Isoforms Circulation Research. May, 2002 | Pubmed ID: 12039797 Generation af humane hjerneorganoider til mitokondriesygdom Modellering Stephanie Le1, Laura Petersilie2, Gizem Inak1,4, Carmen Menacho-Pando1, Karl W. Kafitz2, Agnieszka Rybak-Wolf3, Nikolaus Rajewsky3, Christine R. Rose2, Alessandro Prigione1,5 1Department of General Pediatrics, Neonatology and Pediatric Cardiology, Duesseldorf University Hospital, Medical Faculty, Heinrich Heine University, 2Institute of Neurobiology, Heinrich Heine University, 3Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrueck Center for Molecular Medicine (MDC), 4Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, 5Max Delbrueck Center for Molecular Medicine (MDC) JoVE 62756 Neuroscience Imaging af intracellulære ATP i Organotypic væv skiver af muse hjernen ved hjælp af FRET-baseret sensor ATeam 1,03Yemk Rodrigo Lerchundi*1, Karl W. Kafitz*1, Marcel Färfers1, Felix Beyer2, Na Huang1, Christine R. Rose1 1Institute of Neurobiology, Heinrich Heine University Düsseldorf, 2Department of Neurology, Düsseldorf University Hospital JoVE 60294 Neuroscience Dobbeltløbet og koncentrisk Mikroelektroder til måling af Ekstracellulær Ion Signaler i hjernevæv Nicole Haack1, Simone Durry1, Karl W. Kafitz1, Mitchell Chesler2, Christine R. Rose1 1Institute of Neurobiology, Heinrich Heine University Düsseldorf, 2Departments of Physiology and Neuroscience, New York University School of Medicine Neuroscience Multi-foton Intracellulær Natrium Imaging Kombineret med UV-medieret Focal Uncaging af glutamat i CA1 pyramideneuroner Christian Kleinhans*1, Karl W. Kafitz*1, Christine R. Rose1 1Institute of Neurobiology, Heinrich Heine University Düsseldorf JoVE 52038 Neuroscience
Generation af humane hjerneorganoider til mitokondriesygdom Modellering Stephanie Le1, Laura Petersilie2, Gizem Inak1,4, Carmen Menacho-Pando1, Karl W. Kafitz2, Agnieszka Rybak-Wolf3, Nikolaus Rajewsky3, Christine R. Rose2, Alessandro Prigione1,5 1Department of General Pediatrics, Neonatology and Pediatric Cardiology, Duesseldorf University Hospital, Medical Faculty, Heinrich Heine University, 2Institute of Neurobiology, Heinrich Heine University, 3Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrueck Center for Molecular Medicine (MDC), 4Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, 5Max Delbrueck Center for Molecular Medicine (MDC) JoVE 62756 Neuroscience
Imaging af intracellulære ATP i Organotypic væv skiver af muse hjernen ved hjælp af FRET-baseret sensor ATeam 1,03Yemk Rodrigo Lerchundi*1, Karl W. Kafitz*1, Marcel Färfers1, Felix Beyer2, Na Huang1, Christine R. Rose1 1Institute of Neurobiology, Heinrich Heine University Düsseldorf, 2Department of Neurology, Düsseldorf University Hospital JoVE 60294 Neuroscience
Dobbeltløbet og koncentrisk Mikroelektroder til måling af Ekstracellulær Ion Signaler i hjernevæv Nicole Haack1, Simone Durry1, Karl W. Kafitz1, Mitchell Chesler2, Christine R. Rose1 1Institute of Neurobiology, Heinrich Heine University Düsseldorf, 2Departments of Physiology and Neuroscience, New York University School of Medicine Neuroscience
Multi-foton Intracellulær Natrium Imaging Kombineret med UV-medieret Focal Uncaging af glutamat i CA1 pyramideneuroner Christian Kleinhans*1, Karl W. Kafitz*1, Christine R. Rose1 1Institute of Neurobiology, Heinrich Heine University Düsseldorf JoVE 52038 Neuroscience