Csaba Fekete Laboratory of Integrative Neuroendocrinology Institute of Experimental Medicine Biography Publications Institution JoVE Articles Csaba Fekete has not added a biography. If you are Csaba Fekete and would like to personalize this page please email our Author Liaison for assistance. Publications Author Correction: A Previously Uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is Related to Evolutionary Adaptation, Energy Balance, and Kidney Physiology Nature Communications. Jun, 2023 | Pubmed ID: 37322005 A Previously Uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is Related to Evolutionary Adaptation, Energy Balance, and Kidney Physiology Nature Communications. May, 2023 | Pubmed ID: 37248239 Axonal T3 Uptake and Transport Can Trigger Thyroid Hormone Signaling in the Brain ELife. May, 2023 | Pubmed ID: 37204837 Unique, Specific CART Receptor-Independent Regulatory Mechanism of CART(55-102) Peptide in Spinal Nociceptive Transmission and Its Relation to Dipeptidyl-Peptidase 4 (DDP4) International Journal of Molecular Sciences. Jan, 2023 | Pubmed ID: 36674439 Different Hypothalamic Mechanisms Control Decreased Circulating Thyroid Hormone Levels in Infection and Fasting-Induced Non-Thyroidal Illness Syndrome in Male Thyroid Hormone Action Indicator Mice Thyroid : Official Journal of the American Thyroid Association. Jan, 2023 | Pubmed ID: 36322711 Tetrabromobisphenol A and Diclazuril Evoke Tissue-Specific Changes of Thyroid Hormone Signaling in Male Thyroid Hormone Action Indicator Mice International Journal of Molecular Sciences. Nov, 2022 | Pubmed ID: 36499108 Origin of Thyrotropin-releasing Hormone Neurons That Innervate the Tuberomammillary Nuclei Brain Structure & Function. Sep, 2022 | Pubmed ID: 35934753 The Metabolic Stress Response: Adaptation to Acute-, Repeated- and Chronic Challenges in Mice IScience. Aug, 2022 | Pubmed ID: 35880047 Triiodothyronine (T3) Promotes Brown Fat Hyperplasia Via Thyroid Hormone Receptor α Mediated Adipocyte Progenitor Cell Proliferation Nature Communications. Jun, 2022 | Pubmed ID: 35697700 Hypothalamic Nesfatin-1 Resistance May Underlie the Development of Type 2 Diabetes Mellitus in Maternally Undernourished Non-obese Rats Frontiers in Neuroscience. 2022 | Pubmed ID: 35386592 Pars Tuberalis As a Key Regulator of Neuroendocrine Functions Nature Reviews. Endocrinology. Jun, 2022 | Pubmed ID: 35361916 Tanycyte Specific Ablation of Diacylglycerol Lipase Alpha Stimulates the Hypothalamic-pituitary-thyroid Axis by Decreasing the Endocannabinoid Mediated Inhibition of TRH Release Journal of Neuroendocrinology. Jan, 2022 | Pubmed ID: 34970803 Expression of Glucagon-like Peptide 1 Receptor in Neuropeptide Y Neurons of the Arcuate Nucleus in Mice Brain Structure & Function. Jan, 2022 | Pubmed ID: 34596755 Distribution and Ultrastructural Localization of the Glucagon-like Peptide-1 Receptor (GLP-1R) in the Rat Brain Brain Structure & Function. Jan, 2021 | Pubmed ID: 33341919 Glucagon-Like Peptide-1 Regulates the Proopiomelanocortin Neurons of the Arcuate Nucleus Both Directly and Indirectly Via Presynaptic Action Neuroendocrinology. 2021 | Pubmed ID: 33152734 Semaglutide Lowers Body Weight in Rodents Via Distributed Neural Pathways JCI Insight. Mar, 2020 | Pubmed ID: 32213703 A Glial-Neuronal Circuit in the Median Eminence Regulates Thyrotropin-Releasing Hormone-Release Via the Endocannabinoid System IScience. Mar, 2020 | Pubmed ID: 32143135 Thyrotropin-Releasing-Hormone-Synthesizing Neurons of the Hypothalamic Paraventricular Nucleus Are Inhibited by Glycinergic Inputs Thyroid : Official Journal of the American Thyroid Association. Dec, 2019 | Pubmed ID: 31659941 Type 2 Deiodinase Polymorphism Causes ER Stress and Hypothyroidism in the Brain The Journal of Clinical Investigation. Jan, 2019 | Pubmed ID: 30352046 Chronic Amyloid β Oligomer Infusion Evokes Sustained Inflammation and Microglial Changes in the Rat Hippocampus Via NLRP3 Neuroscience. May, 2019 | Pubmed ID: 29522854 Transcellular Stomach Absorption of a Derivatized Glucagon-like Peptide-1 Receptor Agonist Science Translational Medicine. Nov, 2018 | Pubmed ID: 30429357 Endocannabinoid and Nitric Oxide Systems of the Hypothalamic Paraventricular Nucleus Mediate Effects of NPY on Energy Expenditure Molecular Metabolism. Dec, 2018 | Pubmed ID: 30274714 Estradiol Increases Glutamate and GABA Neurotransmission into GnRH Neurons Via Retrograde NO-Signaling in Proestrous Mice During the Positive Estradiol Feedback Period ENeuro. 2018 | Pubmed ID: 30079374 Glial Cell Type-specific Changes in Spinal Dipeptidyl Peptidase 4 Expression and Effects of Its Inhibitors in Inflammatory and Neuropatic Pain Scientific Reports. 02, 2018 | Pubmed ID: 29472575 Post Mortem Single-cell Labeling with DiI and Immunoelectron Microscopy Unveil the Fine Structure of Kisspeptin Neurons in Humans Brain Structure & Function. Jun, 2018 | Pubmed ID: 29380121 A Transgenic Mouse Model for Detection of Tissue-Specific Thyroid Hormone Action Endocrinology. Feb, 2018 | Pubmed ID: 29253128 Role of TRH/UCN3 Neurons of the Perifornical Area/bed Nucleus of Stria Terminalis Region in the Regulation of the Anorexigenic POMC Neurons of the Arcuate Nucleus in Male Mice and Rats Brain Structure & Function. Apr, 2018 | Pubmed ID: 29124350 Neuronal Connections of the Central Amygdalar Nucleus with Refeeding-activated Brain Areas in Rats Brain Structure & Function. Jan, 2018 | Pubmed ID: 28852859 Transient Hypothyroidism Favors Oligodendrocyte Generation Providing Functional Remyelination in the Adult Mouse Brain ELife. Sep, 2017 | Pubmed ID: 28875931 Localization of Connexin 43 Gap Junctions and Hemichannels in Tanycytes of Adult Mice Brain Research. Oct, 2017 | Pubmed ID: 28803831 Variable Proopiomelanocortin Expression in Tanycytes of the Adult Rat Hypothalamus and Pituitary Stalk The Journal of Comparative Neurology. Feb, 2017 | Pubmed ID: 27503597 Glucagon-Like Peptide-1 Excites Firing and Increases GABAergic Miniature Postsynaptic Currents (mPSCs) in Gonadotropin-Releasing Hormone (GnRH) Neurons of the Male Mice Via Activation of Nitric Oxide (NO) and Suppression of Endocannabinoid Signaling Pathways Frontiers in Cellular Neuroscience. 2016 | Pubmed ID: 27672360 Type 2 Deiodinase Disruption in Astrocytes Results in Anxiety-Depressive-Like Behavior in Male Mice Endocrinology. Sep, 2016 | Pubmed ID: 27501182 Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function Cell Metabolism. May, 2016 | Pubmed ID: 27133129 Elucidation of the Anatomy of a Satiety Network: Focus on Connectivity of the Parabrachial Nucleus in the Adult Rat The Journal of Comparative Neurology. Oct, 2016 | Pubmed ID: 26918800 Altered Gene Expression Profiles of the Hypothalamic Arcuate Nucleus of Male Mice Suggest Profound Developmental Changes in Peptidergic Signaling Neuroendocrinology. 2016 | Pubmed ID: 26338351 Perinatal Deiodinase 2 Expression in Hepatocytes Defines Epigenetic Susceptibility to Liver Steatosis and Obesity Proceedings of the National Academy of Sciences of the United States of America. Nov, 2015 | Pubmed ID: 26508642 Area-specific Analysis of the Distribution of Hypothalamic Neurons Projecting to the Rat Ventral Tegmental Area, with Special Reference to the GABAergic and Glutamatergic Efferents Frontiers in Neuroanatomy. 2015 | Pubmed ID: 26388742 Parallel Regulation of Thyroid Hormone Transporters OATP1c1 and MCT8 During and After Endotoxemia at the Blood-brain Barrier of Male Rodents Endocrinology. Apr, 2015 | Pubmed ID: 25594699 Prevalent Polymorphism in Thyroid Hormone-activating Enzyme Leaves a Genetic Fingerprint That Underlies Associated Clinical Syndromes The Journal of Clinical Endocrinology and Metabolism. Mar, 2015 | Pubmed ID: 25569702 Central Regulation of Hypothalamic-pituitary-thyroid Axis Under Physiological and Pathophysiological Conditions Endocrine Reviews. Apr, 2014 | Pubmed ID: 24423980 The CB1 Receptor Mediates the Peripheral Effects of Ghrelin on AMPK Activity but Not on Growth Hormone Release FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2013 | Pubmed ID: 23982145 CB1 Receptor Mediates the Effects of Glucocorticoids on AMPK Activity in the Hypothalamus The Journal of Endocrinology. Oct, 2013 | Pubmed ID: 23884964 Coordination of Hypothalamic and Pituitary T3 Production Regulates TSH Expression The Journal of Clinical Investigation. Apr, 2013 | Pubmed ID: 23524969 Thyrotropin-releasing Hormone-containing Axons Innervate Histaminergic Neurons in the Tuberomammillary Nucleus Brain Research. Dec, 2012 | Pubmed ID: 23063458 A Novel Pathway Regulates Thyroid Hormone Availability in Rat and Human Hypothalamic Neurosecretory Neurons PloS One. 2012 | Pubmed ID: 22719854 Refeeding-activated Glutamatergic Neurons in the Hypothalamic Paraventricular Nucleus (PVN) Mediate Effects of Melanocortin Signaling in the Nucleus Tractus Solitarius (NTS) Endocrinology. Aug, 2012 | Pubmed ID: 22700769 Distribution of Type 1 Cannabinoid Receptor-expressing Neurons in the Septal-hypothalamic Region of the Mouse: Colocalization with GABAergic and Glutamatergic Markers The Journal of Comparative Neurology. Apr, 2012 | Pubmed ID: 21935941 Retrograde Endocannabinoid Signaling Reduces GABAergic Synaptic Transmission to Gonadotropin-releasing Hormone Neurons Endocrinology. Dec, 2010 | Pubmed ID: 20926585 Distribution of Hypophysiotropic Thyrotropin-releasing Hormone (TRH)-synthesizing Neurons in the Hypothalamic Paraventricular Nucleus of the Mouse The Journal of Comparative Neurology. Oct, 2010 | Pubmed ID: 20737594 Contribution of TNF-alpha and Nuclear Factor-kappaB Signaling to Type 2 Iodothyronine Deiodinase Activation in the Mediobasal Hypothalamus After Lipopolysaccharide Administration Endocrinology. Aug, 2010 | Pubmed ID: 20501675 Distribution and Axonal Projections of Neurons Coexpressing Thyrotropin-releasing Hormone and Urocortin 3 in the Rat Brain The Journal of Comparative Neurology. Dec, 2009 | Pubmed ID: 19844978 The E3 Ubiquitin Ligase TEB4 Mediates Degradation of Type 2 Iodothyronine Deiodinase Molecular and Cellular Biology. Oct, 2009 | Pubmed ID: 19651899 Noradrenergic Innervation of Hypophysiotropic Thyrotropin-releasing Hormone-synthesizing Neurons in Rats Brain Research. Oct, 2009 | Pubmed ID: 19651110 Improved Method for Combination of Immunocytochemistry and Nissl Staining Journal of Neuroscience Methods. Oct, 2009 | Pubmed ID: 19615409 Efferent Projections of Thyrotropin-releasing Hormone-synthesizing Neurons Residing in the Anterior Parvocellular Subdivision of the Hypothalamic Paraventricular Nucleus The Journal of Comparative Neurology. Jul, 2009 | Pubmed ID: 19425088 Tanycyte Pyroglutamyl Peptidase II Contributes to Regulation of the Hypothalamic-pituitary-thyroid Axis Through Glial-axonal Associations in the Median Eminence Endocrinology. May, 2009 | Pubmed ID: 19179432 Type 1 Cannabinoid Receptor-containing Axons Innervate Hypophysiotropic Thyrotropin-releasing Hormone-synthesizing Neurons Endocrinology. Jan, 2009 | Pubmed ID: 18818298 Peripheral, but Not Central, CB1 Antagonism Provides Food Intake-independent Metabolic Benefits in Diet-induced Obese Rats Diabetes. Nov, 2008 | Pubmed ID: 18716045 Differential Effects of Refeeding on Melanocortin-responsive Neurons in the Hypothalamic Paraventricular Nucleus Endocrinology. Sep, 2008 | Pubmed ID: 18467436 The Orexigenic Effect of Ghrelin is Mediated Through Central Activation of the Endogenous Cannabinoid System PloS One. Mar, 2008 | Pubmed ID: 18335063 Induction of Type 2 Iodothyronine Deiodinase in the Mediobasal Hypothalamus by Bacterial Lipopolysaccharide: Role of Corticosterone Endocrinology. May, 2008 | Pubmed ID: 18218695 Mitogen-activated Protein Kinase Contributes to Lipopolysaccharide-induced Activation of Corticotropin-releasing Hormone Synthesizing Neurons in the Hypothalamic Paraventricular Nucleus Endocrinology. May, 2008 | Pubmed ID: 18187539 Contribution of Noradrenergic and Adrenergic Cell Groups of the Brainstem and Agouti-related Protein-synthesizing Neurons of the Arcuate Nucleus to Neuropeptide-y Innervation of Corticotropin-releasing Hormone Neurons in Hypothalamic Paraventricular Nucleus of the Rat Endocrinology. Nov, 2007 | Pubmed ID: 17690163 Expression Patterns of WSB-1 and USP-33 Underlie Cell-specific Posttranslational Control of Type 2 Deiodinase in the Rat Brain Endocrinology. Oct, 2007 | Pubmed ID: 17628004 Negative Feedback Regulation of Hypophysiotropic Thyrotropin-releasing Hormone (TRH) Synthesizing Neurons: Role of Neuronal Afferents and Type 2 Deiodinase Frontiers in Neuroendocrinology. 2007 | Pubmed ID: 17588648 Cocaine- and Amphetamine-regulated Transcript (CART) is Colocalized with the Orexigenic Neuropeptide Y and Agouti-related Protein and Absent from the Anorexigenic Alpha-melanocyte-stimulating Hormone Neurons in the Infundibular Nucleus of the Human Hypothalamus Endocrinology. Sep, 2007 | Pubmed ID: 17525122 Distribution of Type 1 Cannabinoid Receptor (CB1)-immunoreactive Axons in the Mouse Hypothalamus The Journal of Comparative Neurology. Jul, 2007 | Pubmed ID: 17492633 Cocaine- and Amphetamine-regulated Transcript (CART) Expression is Differentially Regulated in the Hypothalamic Paraventricular Nucleus of Lactating Rats Exposed to Suckling or Cold Stimulation Brain Research. Feb, 2007 | Pubmed ID: 17174283 Distribution of Ghrelin-immunoreactive Neuronal Networks in the Human Hypothalamus Brain Research. Dec, 2006 | Pubmed ID: 17113048 Enhanced PIP3 Signaling in POMC Neurons Causes KATP Channel Activation and Leads to Diet-sensitive Obesity The Journal of Clinical Investigation. Jul, 2006 | Pubmed ID: 16794735 Neuroendocrine Implications for the Association Between Cocaine- and Amphetamine Regulated Transcript (CART) and Hypophysiotropic Thyrotropin-releasing Hormone (TRH) Peptides. Aug, 2006 | Pubmed ID: 16730860 Characterization of the Nuclear Factor-kappa B Responsiveness of the Human Dio2 Gene Endocrinology. Sep, 2006 | Pubmed ID: 16728495 Expression of Vesicular Glutamate Transporter-2 in Gonadotrope and Thyrotrope Cells of the Rat Pituitary. Regulation by Estrogen and Thyroid Hormone Status Endocrinology. Aug, 2006 | Pubmed ID: 16675529 Interconnection Between Orexigenic Neuropeptide Y- and Anorexigenic Alpha-melanocyte Stimulating Hormone-synthesizing Neuronal Systems of the Human Hypothalamus Brain Research. Mar, 2006 | Pubmed ID: 16473335 Origin of Cocaine- and Amphetamine-regulated Transcript-containing Axons Innervating Hypophysiotropic Corticotropin-releasing Hormone-synthesizing Neurons in the Rat Endocrinology. Jul, 2005 | Pubmed ID: 15831569 Glutamatergic Innervation of Corticotropin-releasing Hormone- and Thyrotropin-releasing Hormone-synthesizing Neurons in the Hypothalamic Paraventricular Nucleus of the Rat Brain Research. Mar, 2005 | Pubmed ID: 15781046 Hypophysiotropic Thyrotropin-releasing Hormone and Corticotropin-releasing Hormone Neurons of the Rat Contain Vesicular Glutamate Transporter-2 Endocrinology. Jan, 2005 | Pubmed ID: 15486233 Ontogenic Redistribution of Type 2 Deiodinase Messenger Ribonucleic Acid in the Brain of Chicken Endocrinology. Aug, 2004 | Pubmed ID: 15087435 Medullary Adrenergic Neurons Contribute to the Cocaine- and Amphetamine-regulated Transcript-immunoreactive Innervation of Thyrotropin-releasing Hormone Synthesizing Neurons in the Hypothalamic Paraventricular Nucleus Brain Research. Apr, 2004 | Pubmed ID: 15047018 Galanin- but Not Galanin-like Peptide-containing Axon Terminals Innervate Hypophysiotropic TRH-synthesizing Neurons in the Hypothalamic Paraventricular Nucleus Brain Research. Mar, 2004 | Pubmed ID: 14988032 Origin of Cocaine- and Amphetamine-regulated Transcript (CART)-immunoreactive Innervation of the Hypothalamic Paraventricular Nucleus The Journal of Comparative Neurology. Feb, 2004 | Pubmed ID: 14730586 Lipopolysaccharide Induces Type 2 Iodothyronine Deiodinase in the Mediobasal Hypothalamus: Implications for the Nonthyroidal Illness Syndrome Endocrinology. Apr, 2004 | Pubmed ID: 14684601 Origin of Neuropeptide Y-containing Afferents to Gonadotropin-releasing Hormone Neurons in Male Mice Endocrinology. Nov, 2003 | Pubmed ID: 12960087 Histamine-immunoreactive Neurons of the Tuberomammillary Nucleus Are Innervated by Alpha-melanocyte Stimulating Hormone-containing Axons. Generation of a New Histamine Antiserum for Ultrastructural Studies Brain Research. Apr, 2003 | Pubmed ID: 12676366 Neuropeptide Y1 and Y5 Receptors Mediate the Effects of Neuropeptide Y on the Hypothalamic-pituitary-thyroid Axis Endocrinology. Dec, 2002 | Pubmed ID: 12446577 GABA-ergic Innervation of Thyrotropin-releasing Hormone-synthesizing Neurons in the Hypothalamic Paraventricular Nucleus of the Rat Brain Research. Dec, 2002 | Pubmed ID: 12445967 Agouti-related Protein (AGRP) Has a Central Inhibitory Action on the Hypothalamic-pituitary-thyroid (HPT) Axis; Comparisons Between the Effect of AGRP and Neuropeptide Y on Energy Homeostasis and the HPT Axis Endocrinology. Oct, 2002 | Pubmed ID: 12239096 VGF is Required for Obesity Induced by Diet, Gold Thioglucose Treatment, and Agouti and is Differentially Regulated in Pro-opiomelanocortin- and Neuropeptide Y-containing Arcuate Neurons in Response to Fasting The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2002 | Pubmed ID: 12177191 Medullary Adrenergic Neurons Contribute to the Neuropeptide Y-ergic Innervation of Hypophysiotropic Thyrotropin-releasing Hormone-synthesizing Neurons in the Rat Neuroscience Letters. May, 2002 | Pubmed ID: 11983297 Corticotropin-releasing Hormone-synthesizing Neurons of the Human Hypothalamus Receive Neuropeptide Y-immunoreactive Innervation from Neurons Residing Primarily Outside the Infundibular Nucleus The Journal of Comparative Neurology. May, 2002 | Pubmed ID: 11932939 Association of Cocaine- and Amphetamine-regulated Transcript-immunoreactive Elements with Thyrotropin-releasing Hormone-synthesizing Neurons in the Hypothalamic Paraventricular Nucleus and Its Role in the Regulation of the Hypothalamic-pituitary-thyroid Axis During Fasting The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2000 | Pubmed ID: 11125000 Alpha-Melanocyte-stimulating Hormone is Contained in Nerve Terminals Innervating Thyrotropin-releasing Hormone-synthesizing Neurons in the Hypothalamic Paraventricular Nucleus and Prevents Fasting-induced Suppression of Prothyrotropin-releasing Hormone Gene Expression The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2000 | Pubmed ID: 10662844 Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model Richárd Sinkó1,2, Petra Mohácsik1, Csaba Fekete*3, Balázs Gereben*1 1Laboratory of Molecular Cell Metabolism, Institute of Experimental Medicine, 2János Szentágothai PhD School of Neurosciences, Semmelweis University, 3Laboratory of Integrative Neuroendocrinology, Institute of Experimental Medicine JoVE 65657 Neuroscience
Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model Richárd Sinkó1,2, Petra Mohácsik1, Csaba Fekete*3, Balázs Gereben*1 1Laboratory of Molecular Cell Metabolism, Institute of Experimental Medicine, 2János Szentágothai PhD School of Neurosciences, Semmelweis University, 3Laboratory of Integrative Neuroendocrinology, Institute of Experimental Medicine JoVE 65657 Neuroscience