Dale F. Mierke Department of Chemistry Dartmouth College Biography Publications Institution JoVE Articles Dale F. Mierke has not added a biography. If you are Dale F. Mierke and would like to personalize this page please email our Author Liaison for assistance. Publications The IKK-binding Domain of NEMO is an Irregular Coiled Coil with a Dynamic Binding Interface Scientific Reports. Feb, 2019 | Pubmed ID: 30814588 The Peach RGF/GLV Signaling Peptide PCTG134 Is Involved in a Regulatory Circuit That Sustains Auxin and Ethylene Actions Frontiers in Plant Science. 2017 | Pubmed ID: 29075273 Modulating the Dysregulated Migration of Pulmonary Arterial Hypertensive Smooth Muscle Cells with Motif Mimicking Cell Permeable Peptides Current Topics in Peptide & Protein Research. 2015 | Pubmed ID: 27274622 Identification and Characterization of the Interaction Site Between CFLIPL and Calmodulin PloS One. 2015 | Pubmed ID: 26529318 Assembly and Turnover of Short Actin Filaments by the Formin INF2 and Profilin The Journal of Biological Chemistry. Sep, 2015 | Pubmed ID: 26124273 New Monocyclic, Bicyclic, and Tricyclic Ethynylcyanodienones As Activators of the Keap1/Nrf2/ARE Pathway and Inhibitors of Inducible Nitric Oxide Synthase Journal of Medicinal Chemistry. Jun, 2015 | Pubmed ID: 25965897 A Novel Caspase 8 Selective Small Molecule Potentiates TRAIL-induced Cell Death Scientific Reports. May, 2015 | Pubmed ID: 25962125 Small-molecule Inhibitors of JC Polyomavirus Infection Journal of Peptide Science : an Official Publication of the European Peptide Society. Mar, 2015 | Pubmed ID: 25522925 Phosphorylation of Ezrin-radixin-moesin-binding Phosphoprotein 50 (EBP50) by Akt Promotes Stability and Mitogenic Function of S-phase Kinase-associated Protein-2 (Skp2) The Journal of Biological Chemistry. Jan, 2015 | Pubmed ID: 25492869 Computational Design of Selective Peptides to Discriminate Between Similar PDZ Domains in an Oncogenic Pathway Journal of Molecular Biology. Jan, 2015 | Pubmed ID: 25451599 Protein Engineering of the N-terminus of NEMO: Structure Stabilization and Rescue of IKKβ Binding Biochemistry. Nov, 2014 | Pubmed ID: 25286246 Small Molecule Inhibition of the Na(+)/H(+) Exchange Regulatory Factor 1 and Parathyroid Hormone 1 Receptor Interaction Biochemistry. Sep, 2014 | Pubmed ID: 25171053 Monitoring ATP Hydrolysis and ATPase Inhibitor Screening Using (1)H NMR Chemical Communications (Cambridge, England). Oct, 2014 | Pubmed ID: 25170530 Gallic Acid-based Small-molecule Inhibitors of JC and BK Polyomaviral Infection Virus Research. Aug, 2014 | Pubmed ID: 24960120 Engineering a Soluble Parathyroid Hormone GPCR Mimetic Proteins. Jul, 2014 | Pubmed ID: 24375686 Recombinant Production of TEV Cleaved Human Parathyroid Hormone Journal of Peptide Science : an Official Publication of the European Peptide Society. Aug, 2013 | Pubmed ID: 23794508 C-terminus of ETA/ETB Receptors Regulate Endothelin-1 Signal Transmission Journal of Peptide Science : an Official Publication of the European Peptide Society. Apr, 2013 | Pubmed ID: 23436727 Ligand Binding Site Identification by Higher Dimension Molecular Dynamics Journal of Chemical Information and Modeling. Mar, 2013 | Pubmed ID: 23394112 Reining in Polyoma Virus Associated Nephropathy: Design and Characterization of a Template Mimicking BK Viral Coat Protein Cellular Binding Biochemistry. Oct, 2012 | Pubmed ID: 23002929 An Exceptionally Potent Inducer of Cytoprotective Enzymes: Elucidation of the Structural Features That Determine Inducer Potency and Reactivity with Keap1 The Journal of Biological Chemistry. Oct, 2010 | Pubmed ID: 20801881 Hydrophobic Residues in Helix 8 of Cannabinoid Receptor 1 Are Critical for Structural and Functional Properties Biochemistry. Jan, 2010 | Pubmed ID: 20025243 Dual Role of the Second Extracellular Loop of the Cannabinoid Receptor 1: Ligand Binding and Receptor Localization Molecular Pharmacology. Oct, 2009 | Pubmed ID: 19643997 Structural Analysis of the Human Cannabinoid Receptor One Carboxyl-terminus Identifies Two Amphipathic Helices Biopolymers. Jul, 2009 | Pubmed ID: 19274719 PTH and PTH Antagonist Induce Different Conformational Changes in the PTHR1 Receptor Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. May, 2009 | Pubmed ID: 19063682 Residue 17 of Sauvagine Cross-links to the First Transmembrane Domain of Corticotropin-releasing Factor Receptor 1 (CRFR1) The Journal of Biological Chemistry. Dec, 2008 | Pubmed ID: 18955489 Phosphorylation-dependent Trafficking of GluR2-containing AMPA Receptors in the Nucleus Accumbens Plays a Critical Role in the Reinstatement of Cocaine Seeking The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2008 | Pubmed ID: 18945913 Mapping Peptide Hormone-receptor Interactions Using a Disulfide-trapping Approach Biochemistry. Jun, 2008 | Pubmed ID: 18459800 Mapping Ligand-receptor Interfaces: Approaching the Resolution Limit of Benzophenone-based Photoaffinity Scanning Chemical Biology & Drug Design. Apr, 2008 | Pubmed ID: 18312550 Conformational Changes in the Parathyroid Hormone Receptor Associated with Activation by Agonist Molecular Endocrinology (Baltimore, Md.). May, 2008 | Pubmed ID: 18258686 Produzione, cristallizzazione e determinazione della struttura del dominio iKK-binding di NEMO Adam H. Barczewski1, Michael J. Ragusa1, Dale F. Mierke1, Maria Pellegrini1 1Department of Chemistry, Dartmouth College JoVE 60339 Biochemistry
Produzione, cristallizzazione e determinazione della struttura del dominio iKK-binding di NEMO Adam H. Barczewski1, Michael J. Ragusa1, Dale F. Mierke1, Maria Pellegrini1 1Department of Chemistry, Dartmouth College JoVE 60339 Biochemistry