Dalibor Sames Department of Chemistry Columbia University Biography Publications Institution JoVE Articles Dalibor Sames has not added a biography. If you are Dalibor Sames and would like to personalize this page please email our Author Liaison for assistance. Publications C-H Arylation of Pyridines: High Regioselectivity As a Consequence of the Electronic Character of C-H Bonds and Heteroarene Ring Journal of the American Chemical Society. Oct, 2011 | Pubmed ID: 21939181 Intermolecular Energy Transfer from Tb3+ to Eu3+ in Aqueous Aggregates and on the Surface of Human Cells Organic Letters. Jun, 2011 | Pubmed ID: 21563789 Expanding the Use of Fluorogenic Enzyme Reporter Substrates to Imaging Metabolic Flux Changes: the Activity Measurement of 5α-steroid Reductase in Intact Mammalian Cells ACS Chemical Biology. Nov, 2010 | Pubmed ID: 20863068 (-)-CHANA, a Fluorogenic Probe for Detecting Amyloid Binding Alcohol Dehydrogenase HSD10 Activity in Living Cells ACS Chemical Biology. Dec, 2010 | Pubmed ID: 20836522 C-H Bonds As Ubiquitous Functionality: a General Approach to Complex Arylated Imidazoles Via Regioselective Sequential Arylation of All Three C-H Bonds and Regioselective N-alkylation Enabled by SEM-group Transposition The Journal of Organic Chemistry. Aug, 2010 | Pubmed ID: 20608749 Development of PH-responsive Fluorescent False Neurotransmitters Journal of the American Chemical Society. Jul, 2010 | Pubmed ID: 20540519 C-H Bond Functionalization Via Hydride Transfer: Direct Coupling of Unactivated Alkynes and Sp(3) C-H Bonds Catalyzed by Platinum Tetraiodide Journal of the American Chemical Society. Nov, 2009 | Pubmed ID: 19852462 C-H Bond Functionalization Via Hydride Transfer: Synthesis of Dihydrobenzopyrans from Ortho-vinylaryl Akyl Ethers Organic Letters. Jul, 2009 | Pubmed ID: 19548698 Fluorescent False Neurotransmitters Visualize Dopamine Release from Individual Presynaptic Terminals Science (New York, N.Y.). Jun, 2009 | Pubmed ID: 19423778 C-H Bonds As Ubiquitous Functionality: a General Approach to Complex Arylated Pyrazoles Via Sequential Regioselective C-arylation and N-alkylation Enabled by SEM-group Transposition Journal of the American Chemical Society. Mar, 2009 | Pubmed ID: 19206533 C-H Bond Functionalization Via Hydride Transfer: Lewis Acid Catalyzed Alkylation Reactions by Direct Intramolecular Coupling of Sp3 C-H Bonds and Reactive Alkenyl Oxocarbenium Intermediates Journal of the American Chemical Society. Jan, 2009 | Pubmed ID: 19099474 Imaging Induction of Cytoprotective Enzymes in Intact Human Cells: Coumberone, a Metabolic Reporter for Human AKR1C Enzymes Reveals Activation by Panaxytriol, an Active Component of Red Ginseng Journal of the American Chemical Society. Oct, 2008 | Pubmed ID: 18826220 A Luminescent Sensor for Tyrosine Phosphorylation Organic Letters. Jan, 2008 | Pubmed ID: 18069839 Harnessing Functional Plasticity of Enzymes: a Fluorogenic Probe for Imaging 17beta-HSD10 Dehydrogenase, an Enzyme Involved in Alzheimer's and Parkinson's Diseases Journal of the American Chemical Society. Nov, 2007 | Pubmed ID: 17958419 Ruthenium Catalyzed Decarbonylative Arylation at Sp3 Carbon Centers in Pyrrolidine and Piperidine Heterocycles Journal of the American Chemical Society. Sep, 2007 | Pubmed ID: 17803274 Transposing Molecular Fluorescent Switches into the Near-IR: Development of Luminogenic Reporter Substrates for Redox Metabolism Journal of the American Chemical Society. Jun, 2007 | Pubmed ID: 17542585 Cocktails of Tb(3+) and Eu(3+) Complexes: a General Platform for the Design of Ratiometric Optical Probes Journal of the American Chemical Society. Jun, 2007 | Pubmed ID: 17518468 Phosphine-free Palladium-catalyzed C-H Bond Arylation of Free (N-H)-indoles and Pyrroles The Journal of Organic Chemistry. Feb, 2007 | Pubmed ID: 17288392 Sp3 C-H Bond Arylation Directed by Amidine Protecting Group: Alpha-arylation of Pyrrolidines and Piperidines Journal of the American Chemical Society. Nov, 2006 | Pubmed ID: 17076471 Synthesis of Luminescent Heterometallic Bis-lanthanide Complexes Via Selective, Sequential Metallation Chemical Communications (Cambridge, England). Oct, 2006 | Pubmed ID: 17024267 Fluorogenic Metabolic Probes for Direct Activity Readout of Redox Enzymes: Selective Measurement of Human AKR1C2 in Living Cells Proceedings of the National Academy of Sciences of the United States of America. Sep, 2006 | Pubmed ID: 16938874 Phosphorylation State-responsive Lanthanide Peptide Conjugates: a Luminescence Switch Based on Reversible Complex Reorganization Organic Letters. Jun, 2006 | Pubmed ID: 16774241 Catalytic C-H Arylation of SEM-protected Azoles with Palladium Complexes of NHCs and Phosphines Organic Letters. May, 2006 | Pubmed ID: 16671761 C-H Bond Functionalization in Complex Organic Synthesis Science (New York, N.Y.). Apr, 2006 | Pubmed ID: 16601184 Oxidative C-arylation of Free (NH)-heterocycles Via Direct Sp3 C-H Bond Functionalization [J. Am. Chem. Soc. 2004, 126, 13244-13246] Journal of the American Chemical Society. Mar, 2006 | Pubmed ID: 16506793 Selective and Catalytic Arylation of N-phenylpyrrolidine: (sp3) C-H Bond Functionalization in the Absence of a Directing Group [J. Am. Chem. Soc. 2005, 127, 5284-5285] Journal of the American Chemical Society. Mar, 2006 | Pubmed ID: 16506792 Fluoromorphic Substrates for Fatty Acid Metabolism: Highly Sensitive Probes for Mammalian Medium-chain Acyl-CoA Dehydrogenase Angewandte Chemie (International Ed. in English). Jan, 2006 | Pubmed ID: 16365837 Room Temperature Intramolecular Hydro-O-alkylation of Aldehydes: Sp3 C-H Functionalization Via a Lewis Acid Catalyzed Tandem 1,5-hydride Transfer/cyclization Organic Letters. Nov, 2005 | Pubmed ID: 16288523 Room Temperature Hydroalkylation of Electron-deficient Olefins: Sp3 C-H Functionalization Via a Lewis Acid-catalyzed Intramolecular Redox Event Journal of the American Chemical Society. Sep, 2005 | Pubmed ID: 16131169 A New Fluorogenic Transformation: Development of an Optical Probe for Coenzyme Q Organic Letters. Jun, 2005 | Pubmed ID: 15932212 Direct Palladium-catalyzed C-2 and C-3 Arylation of Indoles: a Mechanistic Rationale for Regioselectivity Journal of the American Chemical Society. Jun, 2005 | Pubmed ID: 15926829 Selective and Catalytic Arylation of N-phenylpyrrolidine: Sp3 C-H Bond Functionalization in the Absence of a Directing Group Journal of the American Chemical Society. Apr, 2005 | Pubmed ID: 15826142 Direct C-arylation of Free (NH)-indoles and Pyrroles Catalyzed by Ar-Rh(III) Complexes Assembled in Situ Journal of the American Chemical Society. Apr, 2005 | Pubmed ID: 15810815 Design of Optical Switches As Metabolic Indicators: New Fluorogenic Probes for Monoamine Oxidases (MAO A and B) Journal of the American Chemical Society. Apr, 2005 | Pubmed ID: 15796498 Site-specific Phenylation of Pyridine Catalyzed by Phosphido-bridged Ruthenium Dimer Complexes: a Prototype for C-H Arylation of Electron-deficient Heteroarenes Journal of the American Chemical Society. Mar, 2005 | Pubmed ID: 15771470 Two-photon Induced Uncaging of a Reactive Intermediate. Multiphoton in Situ Detection of a Potentially Valuable Label for Biological Applications The Journal of Organic Chemistry. Mar, 2005 | Pubmed ID: 15760198 Oxidative C-arylation of Free (NH)-heterocycles Via Direct (sp3) C-H Bond Functionalization Journal of the American Chemical Society. Oct, 2004 | Pubmed ID: 15479077 Direct C-H Bond Arylation: Selective Palladium-catalyzed C2-arylation of N-substituted Indoles Organic Letters. Aug, 2004 | Pubmed ID: 15330642 Cross-coupling of Sp(3) C-H Bonds and Alkenes: Catalytic Cyclization of Alkene-amide Substrates Journal of the American Chemical Society. Jun, 2004 | Pubmed ID: 15161275 New Tools for Molecular Imaging of Redox Metabolism: Development of a Fluorogenic Probe for 3 Alpha-hydroxysteroid Dehydrogenases Journal of the American Chemical Society. Mar, 2004 | Pubmed ID: 14982413 Ru(III)-catalyzed Cyclization of Arene-alkene Substrates Via Intramolecular Electrophilic Hydroarylation Organic Letters. Feb, 2004 | Pubmed ID: 14961628 Fully Synthetic Carbohydrate-based Vaccines in Biochemically Relapsed Prostate Cancer: Clinical Trial Results with Alpha-N-acetylgalactosamine-O-serine/threonine Conjugate Vaccine Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2003 | Pubmed ID: 14645418 Concise Synthesis of the Chemopreventitive Agent (+/-)-deguelin Via a Key 6-endo Hydroarylation Organic Letters. Oct, 2003 | Pubmed ID: 14572247 Cobalt-catalyzed Arylation of Azole Heteroarenes Via Direct C-H Bond Functionalization Organic Letters. Oct, 2003 | Pubmed ID: 14507184 Diversity Synthesis Via C-H Bond Functionalization: Concept-guided Development of New C-arylation Methods for Imidazoles Journal of the American Chemical Society. Sep, 2003 | Pubmed ID: 12940740 Reactivity of Functional Groups on the Protein Surface: Development of Epoxide Probes for Protein Labeling Journal of the American Chemical Society. Jul, 2003 | Pubmed ID: 12837082 Selective C-arylation of Free (NH)-heteroarenes Via Catalytic C-H Bond Functionalization Journal of the American Chemical Society. May, 2003 | Pubmed ID: 12720429 Pt(IV)-catalyzed Cyclization of Arene-alkyne Substrates Via Intramolecular Electrophilic Hydroarylation Organic Letters. Apr, 2003 | Pubmed ID: 12659572 C-C Bond Formation Via C-H Bond Activation: Catalytic Arylation and Alkenylation of Alkane Segments Journal of the American Chemical Society. Nov, 2002 | Pubmed ID: 12418875 C-C Bond Formation Via C-H Bond Activation: Synthesis of the Core of Teleocidin B4 Journal of the American Chemical Society. Oct, 2002 | Pubmed ID: 12358522 Principles of Mucin Architecture: Structural Studies on Synthetic Glycopeptides Bearing Clustered Mono-, Di-, Tri-, and Hexasaccharide Glycodomains Journal of the American Chemical Society. Aug, 2002 | Pubmed ID: 12175243 Total Synthesis of (-)-rhazinilam: Asymmetric C[bond]H Bond Activation Via the Use of a Chiral Auxiliary Journal of the American Chemical Society. Jun, 2002 | Pubmed ID: 12059212 متصور النسخة الدوبامين في محطات قبل المشبكي فردية مع FFNs Hui Zhang1,2, Niko G. Gubernator3,4, Minerva Yue1, Roland G. W. Staal1, Eugene V. Mosharov1, Daniela Pereira1, Vojtech Balsanek3, Paul A. Vadola3, Bipasha Mukherjee5, Robert H. Edwards5, David Sulzer1,2,6, Dalibor Sames3 1Departments of Neurology, Columbia University, 2Departments of Psychiatry and Pharmacology, Columbia University, 3Department of Chemistry, Columbia University, 4eMolecules, Inc., 5Departments of Neurology and Physiology, University of California School of Medicine, San Francisco, 6Division of Molecular Therapeutics, New York Psychiatric Institute JoVE 1562 Biology
متصور النسخة الدوبامين في محطات قبل المشبكي فردية مع FFNs Hui Zhang1,2, Niko G. Gubernator3,4, Minerva Yue1, Roland G. W. Staal1, Eugene V. Mosharov1, Daniela Pereira1, Vojtech Balsanek3, Paul A. Vadola3, Bipasha Mukherjee5, Robert H. Edwards5, David Sulzer1,2,6, Dalibor Sames3 1Departments of Neurology, Columbia University, 2Departments of Psychiatry and Pharmacology, Columbia University, 3Department of Chemistry, Columbia University, 4eMolecules, Inc., 5Departments of Neurology and Physiology, University of California School of Medicine, San Francisco, 6Division of Molecular Therapeutics, New York Psychiatric Institute JoVE 1562 Biology