Daniel J. Wozniak Department of Microbiology The Ohio State University Biography Publications Institution JoVE Articles Daniel J. Wozniak has not added a biography. If you are Daniel J. Wozniak and would like to personalize this page please email our Author Liaison for assistance. Publications Mucin O-glycans Are Natural Inhibitors of Candida Albicans Pathogenicity Nature Chemical Biology. Jun, 2022 | Pubmed ID: 35668191 Author Correction: Viscoelastic Properties Of Pseudomonas Aeruginosa variant Biofilms Scientific Reports. May, 2022 | Pubmed ID: 35585192 The Wsp System of Links Surface Sensing and Cell Envelope Stress Proceedings of the National Academy of Sciences of the United States of America. 05, 2022 | Pubmed ID: 35476526 Mucoid Pseudomonas Aeruginosa Can Produce Calcium-Gelled Biofilms Independent of the Matrix Components Psl and CdrA Journal of Bacteriology. May, 2022 | Pubmed ID: 35416688 Treating Bacterial Infections with Bacteriophage-Based Enzybiotics: In Vitro, In Vivo and Clinical Application Antibiotics (Basel, Switzerland). Dec, 2021 | Pubmed ID: 34943709 Friends or Foes? Rapid Determination of Dissimilar Colistin and Ciprofloxacin Antagonism of Phages Pharmaceuticals (Basel, Switzerland). Nov, 2021 | Pubmed ID: 34832944 Arginine Induced Biofilm Detachment Using a Novel Rotating-Disc Rheometry Method Frontiers in Cellular and Infection Microbiology. 2021 | Pubmed ID: 34805002 Phage Cocktail Development for Bacteriophage Therapy: Toward Improving Spectrum of Activity Breadth and Depth Pharmaceuticals (Basel, Switzerland). Oct, 2021 | Pubmed ID: 34681243 Optimization of TopoIV Potency, ADMET Properties, and HERG Inhibition of 5-Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Identification of a Lead with Efficacy Against MRSA Journal of Medicinal Chemistry. 10, 2021 | Pubmed ID: 34614347 Improving Phage-Biofilm In Vitro Experimentation Viruses. 06, 2021 | Pubmed ID: 34205417 Mycobacterium Abscessus Biofilms Have Viscoelastic Properties Which May Contribute to Their Recalcitrance in Chronic Pulmonary Infections Scientific Reports. 03, 2021 | Pubmed ID: 33658597 Pseudomonas Aeruginosa Aggregates in Cystic Fibrosis Sputum Produce Exopolysaccharides That Likely Impede Current Therapies Cell Reports. 02, 2021 | Pubmed ID: 33626358 Biofilm Mechanics: Implications in Infection and Survival Biofilm. Dec, 2020 | Pubmed ID: 33447803 Dioxane-Linked Amide Derivatives As Novel Bacterial Topoisomerase Inhibitors Against Gram-Positive ACS Medicinal Chemistry Letters. Dec, 2020 | Pubmed ID: 33335666 Leukocidins and the Nuclease Nuc Prevent Neutrophil-Mediated Killing of Staphylococcus Aureus Biofilms Infection and Immunity. 09, 2020 | Pubmed ID: 32719153 The Versatile Pseudomonas Aeruginosa Biofilm Matrix Protein CdrA Promotes Aggregation Through Different Extracellular Exopolysaccharide Interactions Journal of Bacteriology. 09, 2020 | Pubmed ID: 32661078 Evaluation of Peptide-Based Probes Toward Diagnostic Imaging of Bacterial Biofilm-Associated Infections ACS Infectious Diseases. 08, 2020 | Pubmed ID: 32603591 Ultrastructure Imaging of Pseudomonas Aeruginosa Lawn Biofilms and Eradication of the Tobramycin-resistant Variants Under in Vitro Electroceutical Treatment Scientific Reports. 06, 2020 | Pubmed ID: 32555250 Novel Aminoglycoside-Tolerant Phoenix Colony Variants of Pseudomonas Aeruginosa Antimicrobial Agents and Chemotherapy. 08, 2020 | Pubmed ID: 32540981 Elevated Exopolysaccharide Levels in Pseudomonas Aeruginosa Flagellar Mutants Have Implications for Biofilm Growth and Chronic Infections PLoS Genetics. 06, 2020 | Pubmed ID: 32530919 Novel Bacterial Topoisomerase Inhibitors Derived from Isomannide European Journal of Medicinal Chemistry. Aug, 2020 | Pubmed ID: 32402932 Biofilms Release Leukocidins to Elicit Extracellular Trap Formation and Evade Neutrophil-mediated Killing Proceedings of the National Academy of Sciences of the United States of America. 07, 2018 | Pubmed ID: 29941565 Pseudomonas Aeruginosa Rugose Small-colony Variants Evade Host Clearance, Are Hyper-inflammatory, and Persist in Multiple Host Environments PLoS Pathogens. 02, 2018 | Pubmed ID: 29394295 Electric Field Based Dressing Disrupts Mixed-Species Bacterial Biofilm Infection and Restores Functional Wound Healing Annals of Surgery. Nov, 2017 | Pubmed ID: 29099398 Histopathological Comparisons of Staphylococcus Aureus and Pseudomonas Aeruginosa Experimental Infected Porcine Burn Wounds Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 05, 2017 | Pubmed ID: 28466497 The Exopolysaccharide Psl-eDNA Interaction Enables the Formation of a Biofilm Skeleton in Pseudomonas Aeruginosa Environmental Microbiology Reports. Apr, 2015 | Pubmed ID: 25472701 Mixed-species Biofilm Compromises Wound Healing by Disrupting Epidermal Barrier Function The Journal of Pathology. Aug, 2014 | Pubmed ID: 24771509 First Evidence of Sternal Wound Biofilm Following Cardiac Surgery PloS One. 2013 | Pubmed ID: 23936415 AmrZ Beta-sheet Residues Are Essential for DNA Binding and Transcriptional Control of Pseudomonas Aeruginosa Virulence Genes Journal of Bacteriology. Oct, 2010 | Pubmed ID: 20709902 Novel Bacterial Diversity and Fragmented EDNA Identified in Hyperbiofilm-Forming Pseudomonas Aeruginosa Rugose Small Colony Variant IScience. | Pubmed ID: 32058950 Sequential Ubiquitination of NLRP3 by RNF125 and Cbl-b Limits Inflammasome Activation and Endotoxemia The Journal of Experimental Medicine. | Pubmed ID: 31999304 Mucin Glycans Attenuate the Virulence of Pseudomonas Aeruginosa in Infection Nature Microbiology. | Pubmed ID: 31611643 Effect of Mycobacterium Tuberculosis Enhancement of Macrophage P-Glycoprotein Expression and Activity on Intracellular Survival During Antituberculosis Drug Treatment The Journal of Infectious Diseases. | Pubmed ID: 31412123 Pseudomonas Aeruginosa Interstrain Dynamics and Selection of Hyperbiofilm Mutants During a Chronic Infection MBio. | Pubmed ID: 31409682 Cystic Fibrosis and Pseudomonas Aeruginosa: the Host-Microbe Interface Clinical Microbiology Reviews. | Pubmed ID: 31142499 1,3-Dioxane-Linked Bacterial Topoisomerase Inhibitors with Enhanced Antibacterial Activity and Reduced HERG Inhibition ACS Infectious Diseases. | Pubmed ID: 31041863 Mucoid Pseudomonas Aeruginosa and Regional Inflammation in the Cystic Fibrosis Lung Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. | Pubmed ID: 31036488 Treatment with the Pseudomonas Aeruginosa Glycoside Hydrolase PslG Combats Wound Infection by Improving Antibiotic Efficacy and Host Innate Immune Activity Antimicrobial Agents and Chemotherapy. | Pubmed ID: 30988141 Electroceutical Treatment of Pseudomonas Aeruginosa Biofilms Scientific Reports. | Pubmed ID: 30765750 Staphylococcus Aureus Biofilm Infection Compromises Wound Healing by Causing Deficiencies in Granulation Tissue Collagen Annals of Surgery. | Pubmed ID: 30614873 Genomic and Phenotypic Diversity Among Ten Laboratory Isolates of PAO1 Journal of Bacteriology. | Pubmed ID: 30530517 CdrA Interactions Within the Pseudomonas Aeruginosa Biofilm Matrix Safeguard It from Proteolysis and Promote Cellular Packing MBio. | Pubmed ID: 30254118 Viscoelastic Properties of Pseudomonas Aeruginosa Variant Biofilms Scientific Reports. | Pubmed ID: 29946126 Synthesis and Anti-staphylococcal Activity of Novel Bacterial Topoisomerase Inhibitors with a 5-amino-1,3-dioxane Linker Moiety Bioorganic & Medicinal Chemistry Letters. | Pubmed ID: 29871847 Use of a Leukocyte-targeted Peptide Probe As a Potential Tracer for Imaging the Tuberculosis Granuloma Tuberculosis (Edinburgh, Scotland). | Pubmed ID: 29623875 Mixed Communities of Mucoid and Nonmucoid Exhibit Enhanced Resistance to Host Antimicrobials MBio. | Pubmed ID: 29588399 Congo Red Stain Identifies Matrix Overproduction and Is an Indirect Measurement for C-di-GMP in Many Species of Bacteria Methods in Molecular Biology (Clifton, N.J.). | Pubmed ID: 28889292 Modifications of Pseudomonas Aeruginosa Cell Envelope in the Cystic Fibrosis Airway Alters Interactions with Immune Cells Scientific Reports. | Pubmed ID: 28684799 Staphylococcus Aureus Protein A Mediates Interspecies Interactions at the Cell Surface of Pseudomonas Aeruginosa MBio. | Pubmed ID: 27222468 Pseudomonas Aeruginosa AmrZ Binds to Four Sites in the AlgD Promoter, Inducing DNA-AmrZ Complex Formation and Transcriptional Activation Journal of Bacteriology. | Pubmed ID: 27185826 What's on the Outside Matters: The Role of the Extracellular Polymeric Substance of Gram-negative Biofilms in Evading Host Immunity and As a Target for Therapeutic Intervention The Journal of Biological Chemistry. | Pubmed ID: 27129225 Prevention and Treatment of Staphylococcus Aureus Biofilms Expert Review of Anti-infective Therapy. | Pubmed ID: 26646248 The Pseudomonas Aeruginosa AmrZ C-terminal Domain Mediates Tetramerization and is Required for Its Activator and Repressor Functions Environmental Microbiology Reports. | Pubmed ID: 26549743 A Novel Technique Using Potassium Permanganate and Reflectance Confocal Microscopy to Image Biofilm Extracellular Polymeric Matrix Reveals Non-eDNA Networks in Pseudomonas Aeruginosa Biofilms Pathogens and Disease. | Pubmed ID: 26536894 Characterization of the Pseudomonas Aeruginosa Glycoside Hydrolase PslG Reveals That Its Levels Are Critical for Psl Polysaccharide Biosynthesis and Biofilm Formation The Journal of Biological Chemistry. | Pubmed ID: 26424791 Pel is a Cationic Exopolysaccharide That Cross-links Extracellular DNA in the Pseudomonas Aeruginosa Biofilm Matrix Proceedings of the National Academy of Sciences of the United States of America. | Pubmed ID: 26311845 Development of a Novel Method for Analyzing Pseudomonas Aeruginosa Twitching Motility and Its Application to Define the AmrZ Regulon PloS One. | Pubmed ID: 26309248 Identification of OprF As a Complement Component C3 Binding Acceptor Molecule on the Surface of Pseudomonas Aeruginosa Infection and Immunity. | Pubmed ID: 25964476 Complete Genome Sequence of Pseudomonas Aeruginosa Mucoid Strain FRD1, Isolated from a Cystic Fibrosis Patient Genome Announcements. | Pubmed ID: 25792066 Surface-associated Microbes Continue to Surprise Us in Their Sophisticated Strategies for Assembling Biofilm Communities F1000prime Reports. | Pubmed ID: 24860649 Cationic Antimicrobial Peptides Promote Microbial Mutagenesis and Pathoadaptation in Chronic Infections PLoS Pathogens. | Pubmed ID: 24763694 A Spider Web Strategy of Type IV Pili-mediated Migration to Build a Fibre-like Psl Polysaccharide Matrix in Pseudomonas Aeruginosa Biofilms Environmental Microbiology. | Pubmed ID: 23425591 Self-produced Exopolysaccharide is a Signal That Stimulates Biofilm Formation in Pseudomonas Aeruginosa Proceedings of the National Academy of Sciences of the United States of America. | Pubmed ID: 23175784 Crystallization of Pseudomonas Aeruginosa AmrZ Protein: Development of a Comprehensive Method for Obtaining and Optimization of Protein-DNA Crystals Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. | Pubmed ID: 22869139 Synthesis of Multiple Pseudomonas Aeruginosa Biofilm Matrix Exopolysaccharides is Post-transcriptionally Regulated Environmental Microbiology. | Pubmed ID: 22513190 The Transcription Factor AmrZ Utilizes Multiple DNA Binding Modes to Recognize Activator and Repressor Sequences of Pseudomonas Aeruginosa Virulence Genes PLoS Pathogens. | Pubmed ID: 22511872 Pseudomonas Biofilm Matrix Composition and Niche Biology FEMS Microbiology Reviews. | Pubmed ID: 22212072 Pseudomonas Aeruginosa Psl Polysaccharide Reduces Neutrophil Phagocytosis and the Oxidative Response by Limiting Complement-mediated Opsonization Cellular Microbiology. | Pubmed ID: 21951860 Direct Evaluation of Pseudomonas Aeruginosa Biofilm Mediators in a Chronic Infection Model Infection and Immunity. | Pubmed ID: 21646454 Epistatic Roles for Pseudomonas Aeruginosa MutS and DinB (DNA Pol IV) in Coping with Reactive Oxygen Species-induced DNA Damage PloS One. | Pubmed ID: 21533111 The Pseudomonas Aeruginosa Exopolysaccharide Psl Facilitates Surface Adherence and NF-kappaB Activation in A549 Cells MBio. | Pubmed ID: 20802825 The Sigma Factor AlgU Plays a Key Role in Formation of Robust Biofilms by Nonmucoid Pseudomonas Aeruginosa Journal of Bacteriology. | Pubmed ID: 20348252 Genetic and Biochemical Analyses of the Pseudomonas Aeruginosa Psl Exopolysaccharide Reveal Overlapping Roles for Polysaccharide Synthesis Enzymes in Psl and LPS Production Molecular Microbiology. | Pubmed ID: 19659934 Pseudomonas Aeruginosa Rugose Small-colony Variants Have Adaptations That Likely Promote Persistence in the Cystic Fibrosis Lung Journal of Bacteriology. | Pubmed ID: 19329647 Standardisierte In-vitro-Assays zur Visualisierung und Quantifizierung von Interaktionen zwischen humanen Neutrophilen und Staphylococcus aureus-Biofilmen Pranav S. J. B. Rana1, Erin S. Gloag2, Daniel J. Wozniak1,2 1Department of Microbiology, The Ohio State University, 2Department of Microbial Infection and Immunity, The Ohio State University JoVE 63773 Immunology and Infection
Standardisierte In-vitro-Assays zur Visualisierung und Quantifizierung von Interaktionen zwischen humanen Neutrophilen und Staphylococcus aureus-Biofilmen Pranav S. J. B. Rana1, Erin S. Gloag2, Daniel J. Wozniak1,2 1Department of Microbiology, The Ohio State University, 2Department of Microbial Infection and Immunity, The Ohio State University JoVE 63773 Immunology and Infection