Daniela Verthelyi Center for Drug Evaluation and Research US Food and Drug Administration Biography Publications Institution JoVE Articles Daniela Verthelyi has not added a biography. If you are Daniela Verthelyi and would like to personalize this page please email our Author Liaison for assistance. Publications Immunology Careers at the NIH, FDA and CDC: Different Paths That Focus on Advancing Public Health Nature Immunology. Feb, 2015 | Pubmed ID: 25594454 Glycosylation, Hypogammaglobulinemia, and Resistance to Viral Infections The New England Journal of Medicine. Apr, 2014 | Pubmed ID: 24716661 Assessment of the Cellular Internalization of Thermolytic Phosphorothioate DNA Oligonucleotide Prodrugs Bioorganic & Medicinal Chemistry. Oct, 2013 | Pubmed ID: 23755885 Scientific Considerations in the Review and Approval of Generic Enoxaparin in the United States Nature Biotechnology. Mar, 2013 | Pubmed ID: 23471071 Hochdurchsatz-quantitative Real-Time Polymerase-Kettenreaktion Für Absolute Und Relative Quantifizierung Der Rhesusaffe Arraytypen I, II Und III Interferon Und Ihre Subtypen Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. Sep, 2012 | Pubmed ID: 22817480 Managing Uncertainty: a Perspective on Risk Pertaining to Product Quality Attributes As They Bear on Immunogenicity of Therapeutic Proteins Journal of Pharmaceutical Sciences. Oct, 2012 | Pubmed ID: 22736548 Regulatory T Cells in γ Irradiation-induced Immune Suppression PloS One. 2012 | Pubmed ID: 22723935 Induction of Ebolavirus Cross-species Immunity Using Retrovirus-like Particles Bearing the Ebola Virus Glycoprotein Lacking the Mucin-like Domain Virology Journal. 2012 | Pubmed ID: 22273269 Ausdruck Profile Menschlichen Interferon-Alpha Und Interferon-Lambda-Untertypen Sind Ligand Und Zelle-abhängige Immunology and Cell Biology. Sep, 2012 | Pubmed ID: 22249201 Mucosal and Peripheral Lin- HLA-DR+ CD11c/123- CD13+ CD14- Mononuclear Cells Are Preferentially Infected During Acute Simian Immunodeficiency Virus Infection Journal of Virology. Jan, 2012 | Pubmed ID: 22090100 TLR9 and TLR7 Agonists Mediate Distinct Type I IFN Responses in Humans and Nonhuman Primates in Vitro and in Vivo Journal of Leukocyte Biology. Jan, 2012 | Pubmed ID: 22058422 The Acceleration of Wound Healing in Primates by the Local Administration of Immunostimulatory CpG Oligonucleotides Biomaterials. Jun, 2011 | Pubmed ID: 21421264 Trace Levels of Innate Immune Response Modulating Impurities (IIRMIs) Synergize to Break Tolerance to Therapeutic Proteins PloS One. 2010 | Pubmed ID: 21203556 Expression and Regulation in the Brain of the Chemokine CCL27 Gene Locus Journal of Neuroimmunology. Aug, 2010 | Pubmed ID: 20605223 High-throughput Real-time PCR for Early Detection and Quantitation of Arenavirus Tacaribe Journal of Virological Methods. Aug, 2009 | Pubmed ID: 19490980 TLRs As Therapeutic Targets in CNS Inflammation and Infection Frontiers in Bioscience (Elite Edition). 2009 | Pubmed ID: 19482661 Overlooking Subvisible Particles in Therapeutic Protein Products: Gaps That May Compromise Product Quality Journal of Pharmaceutical Sciences. Apr, 2009 | Pubmed ID: 18704929 Inhibition of Taq Polymerase As a Method for Screening Heparin for Oversulfated Contaminants Biomaterials. Dec, 2008 | Pubmed ID: 18801571 Neutralizing Antibodies to Therapeutic Enzymes: Considerations for Testing, Prevention and Treatment Nature Biotechnology. Aug, 2008 | Pubmed ID: 18688246 Immunotherapy with CpG Oligonucleotides and Antibodies to TNF-alpha Rescues Neonatal Mice from Lethal Arenavirus-induced Meningoencephalitis Journal of Immunology (Baltimore, Md. : 1950). Jun, 2008 | Pubmed ID: 18523289 The IP10 (CXCL10) Specific CDNA Probe of the MCK-5c Multiprobe RNase Protection Assay Kit Carries Two Nucleotide Insertions That Complicate the Interpretation of Results Cytokine. Feb, 2008 | Pubmed ID: 18226543 Synthetic CpG Oligodeoxynucleotides Augment BAFF- and APRIL-mediated Immunoglobulin Secretion European Journal of Immunology. Jul, 2007 | Pubmed ID: 17557373 GM-CSF Produktion Durch Autoreaktive T-Zellen Ist Erforderlich Für Die Aktivierung Der Microglial Zellen Und Dem Beginn Der Experimentellen Autoimmunen Enzephalomyelitis Journal of Immunology (Baltimore, Md. : 1950). Jan, 2007 | Pubmed ID: 17182538 Use of Thermolytic Protective Groups to Prevent G-tetrad Formation in CpG ODN Type D: Structural Studies and Immunomodulatory Activity in Primates Nucleic Acids Research. 2006 | Pubmed ID: 17130156 Adjuvant Properties of CpG Oligonucleotides in Primates Methods in Molecular Medicine. 2006 | Pubmed ID: 16988453 CpG Oligodeoxynucleotides Protect Newborn Mice from a Lethal Challenge with the Neurotropic Tacaribe Arenavirus Journal of Immunology (Baltimore, Md. : 1950). Apr, 2006 | Pubmed ID: 16585590 Female's Heightened Immune Status: Estrogen, T Cells, and Inducible Nitric Oxide Synthase in the Balance Endocrinology. Feb, 2006 | Pubmed ID: 16418430 Design and Development of Thermolytic DNA Oligonucleotide Prodrugs Annals of the New York Academy of Sciences. Nov, 2005 | Pubmed ID: 16394123 Prevention and Treatment of Cutaneous Leishmaniasis in Primates by Using Synthetic Type D/A Oligodeoxynucleotides Expressing CpG Motifs Infection and Immunity. Aug, 2005 | Pubmed ID: 16041009 Thermolytic CpG-containing DNA Oligonucleotides As Potential Immunotherapeutic Prodrugs Nucleic Acids Research. 2005 | Pubmed ID: 15972797 Use of CpG Oligodeoxynucleotides As Immune Adjuvants Immunological Reviews. Jun, 2004 | Pubmed ID: 15233736 CpG Oligodeoxynucleotides Improve the Response to Hepatitis B Immunization in Healthy and SIV-infected Rhesus Macaques AIDS (London, England). Apr, 2004 | Pubmed ID: 15096802 Immunoregulatory Activity of CpG Oligonucleotides in Humans and Nonhuman Primates Clinical Immunology (Orlando, Fla.). Oct, 2003 | Pubmed ID: 14585277 Differential Signaling by CpG DNA in DCs and B Cells: Not Just TLR9 Trends in Immunology. Oct, 2003 | Pubmed ID: 14552833 Coinjection with CpG-containing Immunostimulatory Oligodeoxynucleotides Reduces the Pathogenicity of a Live Vaccine Against Cutaneous Leishmaniasis but Maintains Its Potency and Durability Infection and Immunity. Sep, 2003 | Pubmed ID: 12933855 Heterogeneity in the Human Response to Immunostimulatory CpG Oligodeoxynucleotides Journal of Immunotherapy (Hagerstown, Md. : 1997). Jul-Aug, 2003 | Pubmed ID: 12843793 Influence of Stimulatory and Suppressive DNA Motifs on Host Susceptibility to Inflammatory Arthritis Arthritis and Rheumatism. Jun, 2003 | Pubmed ID: 12794839 CpG Oligodeoxynucleotides Protect Normal and SIV-infected Macaques from Leishmania Infection Journal of Immunology (Baltimore, Md. : 1950). May, 2003 | Pubmed ID: 12707351 Reduction of CpG-induced Arthritis by Suppressive Oligodeoxynucleotides Arthritis and Rheumatism. Aug, 2002 | Pubmed ID: 12209528 CpG Oligodeoxynucleotides Induce Human Monocytes to Mature into Functional Dendritic Cells European Journal of Immunology. Sep, 2002 | Pubmed ID: 12207346 CpG DNA: Recognition by and Activation of Monocytes Microbes and Infection / Institut Pasteur. Jul, 2002 | Pubmed ID: 12106782 Differential and Competitive Activation of Human Immune Cells by Distinct Classes of CpG Oligodeoxynucleotide Journal of Leukocyte Biology. May, 2002 | Pubmed ID: 11994506 CpG Oligodeoxynucleotides As Vaccine Adjuvants in Primates Journal of Immunology (Baltimore, Md. : 1950). Feb, 2002 | Pubmed ID: 11823494 Hochdurchsatz-quantitative Echtzeit-RT-PCR-Assay zur Bestimmung Expressionsprofile der Typen I und III Interferon-Formationsglieder Lynnsey A. Renn1, Terence C. Theisen1, Maria B. Navarro1, Viraj P. Mane1, Lynnsie M. Schramm1, Kevin D. Kirschman1, Giulia Fabozzi1, Philippa Hillyer1, Montserrat Puig2, Daniela Verthelyi2, Ronald L. Rabin1 1Center for Biologics Evaluation and Research, US Food and Drug Administration, 2Center for Drug Evaluation and Research, US Food and Drug Administration Immunology and Infection
Hochdurchsatz-quantitative Echtzeit-RT-PCR-Assay zur Bestimmung Expressionsprofile der Typen I und III Interferon-Formationsglieder Lynnsey A. Renn1, Terence C. Theisen1, Maria B. Navarro1, Viraj P. Mane1, Lynnsie M. Schramm1, Kevin D. Kirschman1, Giulia Fabozzi1, Philippa Hillyer1, Montserrat Puig2, Daniela Verthelyi2, Ronald L. Rabin1 1Center for Biologics Evaluation and Research, US Food and Drug Administration, 2Center for Drug Evaluation and Research, US Food and Drug Administration Immunology and Infection
