Danny G. Winder Department of Molecular Physiology and Biophysics, Center for Molecular Neuroscience, Kennedy Center for Human Development Vanderbilt University Medical Center Biography Publications Institution JoVE Articles Danny G. Winder has not added a biography. If you are Danny G. Winder and would like to personalize this page please email our Author Liaison for assistance. Publications Discovery of 2-(2-Benzoxazoyl Amino)-4-Aryl-5-Cyanopyrimidine As Negative Allosteric Modulators (NAMs) of Metabotropic Glutamate Receptor 5 (mGlu(5) ): From an Artificial Neural Network Virtual Screen to an In Vivo Tool Compound ChemMedChem. Jan, 2012 | Pubmed ID: 22267125 Stimulus Dynamics Increase the Self-administration of Compound Visual and Auditory Stimuli Neuroscience Letters. Jan, 2012 | Pubmed ID: 22249116 GluN2B Subunit Deletion Reveals Key Role in Acute and Chronic Ethanol Sensitivity of Glutamate Synapses in Bed Nucleus of the Stria Terminalis Proceedings of the National Academy of Sciences of the United States of America. Jan, 2012 | Pubmed ID: 22219357 (3-Cyano-5-fluorophenyl)biaryl Negative Allosteric Modulators of MGlu(5): Discovery of a New Tool Compound with Activity in the OSS Mouse Model of Addiction ACS Chemical Neuroscience. Aug, 2011 | Pubmed ID: 21927650 Loss of Thr286 Phosphorylation Disrupts Synaptic CaMKIIα Targeting, NMDAR Activity and Behavior in Pre-adolescent Mice Molecular and Cellular Neurosciences. Aug, 2011 | Pubmed ID: 21627991 MGluR8 Modulates Excitatory Transmission in the Bed Nucleus of the Stria Terminalis in a Stress-dependent Manner Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Jul, 2011 | Pubmed ID: 21451497 Stress-induced Alterations in Anxiety-like Behavior and Adaptations in Plasticity in the Bed Nucleus of the Stria Terminalis Physiology & Behavior. Aug, 2011 | Pubmed ID: 21396387 Opposing Roles of MGluR8 in Measures of Anxiety Involving Non-social and Social Challenges Behavioural Brain Research. Aug, 2011 | Pubmed ID: 21382421 β-Adrenergic Receptors Enhance Excitatory Transmission in the Bed Nucleus of the Stria Terminalis Through a Corticotrophin-releasing Factor Receptor-dependent and Cocaine-regulated Mechanism Biological Psychiatry. Jun, 2011 | Pubmed ID: 21334600 Altered Anxiety-like Behavior and Long-term Potentiation in the Bed Nucleus of the Stria Terminalis in Adult Mice Exposed to Chronic Social Isolation, Unpredictable Stress, and Ethanol Beginning in Adolescence Alcohol (Fayetteville, N.Y.). Sep, 2011 | Pubmed ID: 21194878 Operant Sensation Seeking Requires Metabotropic Glutamate Receptor 5 (mGluR5) PloS One. 2010 | Pubmed ID: 21152045 An Odyssey of Fear: Homer Stresses New Mechanisms Biological Psychiatry. Dec, 2010 | Pubmed ID: 21075227 Strain Differences in Stress Responsivity Are Associated with Divergent Amygdala Gene Expression and Glutamate-mediated Neuronal Excitability The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2010 | Pubmed ID: 20392957 Distinct Forms of Gq-receptor-dependent Plasticity of Excitatory Transmission in the BNST Are Differentially Affected by Stress Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 20133871 Repeated Homotypic Stress Elevates 2-arachidonoylglycerol Levels and Enhances Short-term Endocannabinoid Signaling at Inhibitory Synapses in Basolateral Amygdala Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Dec, 2009 | Pubmed ID: 19675536 Alcohol Exposure Alters NMDAR Function in the Bed Nucleus of the Stria Terminalis Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Oct, 2009 | Pubmed ID: 19553918 Subcellular Localization of the Antidepressant-sensitive Norepinephrine Transporter BMC Neuroscience. 2009 | Pubmed ID: 19545450 Modulation of Glutamatergic Synaptic Transmission in the Bed Nucleus of the Stria Terminalis Progress in Neuro-psychopharmacology & Biological Psychiatry. Nov, 2009 | Pubmed ID: 19524008 Epitope-tagged Receptor Knock-in Mice Reveal That Differential Desensitization of Alpha2-adrenergic Responses is Because of Ligand-selective Internalization The Journal of Biological Chemistry. May, 2009 | Pubmed ID: 19276088 Operant Sensation Seeking Engages Similar Neural Substrates to Operant Drug Seeking in C57 Mice Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Jun, 2009 | Pubmed ID: 19145223 Dopamine Enhances Fast Excitatory Synaptic Transmission in the Extended Amygdala by a CRF-R1-dependent Process The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2008 | Pubmed ID: 19091975 In Vivo Metabotropic Glutamate Receptor 5 (mGluR5) Antagonism Prevents Cocaine-induced Disruption of Postsynaptically Maintained MGluR5-dependent Long-term Depression The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2008 | Pubmed ID: 18784306 Yohimbine Impairs Extinction of Cocaine-conditioned Place Preference in an Alpha2-adrenergic Receptor Independent Process Learning & Memory (Cold Spring Harbor, N.Y.). Sep, 2008 | Pubmed ID: 18772254 Chronic Ethanol Exposure Leads to Divergent Control of Dopaminergic Synapses in Distinct Target Regions Alcohol (Fayetteville, N.Y.). May, 2008 | Pubmed ID: 18358675 Alpha1-adrenergic Receptor-induced Heterosynaptic Long-term Depression in the Bed Nucleus of the Stria Terminalis is Disrupted in Mouse Models of Affective Disorders Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Sep, 2008 | Pubmed ID: 18046308 Microarray Analysis Reveals Distinctive Signaling Between the Bed Nucleus of the Stria Terminalis, Nucleus Accumbens, and Dorsal Striatum Physiological Genomics. Feb, 2008 | Pubmed ID: 17911379 Alcohol Inhibits NR2B-containing NMDA Receptors in the Ventral Bed Nucleus of the Stria Terminalis Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. May, 2008 | Pubmed ID: 17625498 Group I MGluRs and Long-term Depression: Potential Roles in Addiction? Molecular Neurobiology. Dec, 2007 | Pubmed ID: 17955198 Oxidation of Calmodulin Alters Activation and Regulation of CaMKII Biochemical and Biophysical Research Communications. Apr, 2007 | Pubmed ID: 17343827 Neuropeptide Y and Corticotropin-releasing Factor Bi-directionally Modulate Inhibitory Synaptic Transmission in the Bed Nucleus of the Stria Terminalis Neuropharmacology. Oct, 2006 | Pubmed ID: 16904135 A Method for Single-session Cocaine Self-administration in the Mouse Psychopharmacology. Jul, 2006 | Pubmed ID: 16767412 Extracellular-signal Regulated Kinase 1-dependent Metabotropic Glutamate Receptor 5-induced Long-term Depression in the Bed Nucleus of the Stria Terminalis is Disrupted by Cocaine Administration The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2006 | Pubmed ID: 16554472 Novel Blockade of Protein Kinase A-mediated Phosphorylation of AMPA Receptors The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2006 | Pubmed ID: 16436600 A Channel to Neurodegeneration Nature Medicine. Jan, 2006 | Pubmed ID: 16397545 Cocaine Self-administration Reduces Excitatory Responses in the Mouse Nucleus Accumbens Shell Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Jul, 2006 | Pubmed ID: 16205778 Activation of NR2A-containing NMDA Receptors is Not Obligatory for NMDA Receptor-dependent Long-term Potentiation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2005 | Pubmed ID: 16162920 Group II and III Metabotropic Glutamate Receptors Suppress Excitatory Synaptic Transmission in the Dorsolateral Bed Nucleus of the Stria Terminalis Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Jul, 2005 | Pubmed ID: 15812571 A Potassium Channel Blocker Induces a Long-lasting Enhancement of Corticostriatal Responses Neuropharmacology. Feb, 2005 | Pubmed ID: 15695170 Norepinephrine Modulates Glutamatergic Transmission in the Bed Nucleus of the Stria Terminalis Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Apr, 2005 | Pubmed ID: 15602500 Regulation of CAMP Levels in Area CA1 of Hippocampus by Gi/o-coupled Receptors is Stimulus Dependent in Mice Neuroscience Letters. Nov, 2004 | Pubmed ID: 15489022 High-frequency Stimulation Induces Ethanol-sensitive Long-term Potentiation at Glutamatergic Synapses in the Dorsolateral Bed Nucleus of the Stria Terminalis The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2004 | Pubmed ID: 15215296 A Novel Mouse Brain Slice Preparation of the Hippocampo-accumbens Pathway Journal of Neuroscience Methods. Aug, 2004 | Pubmed ID: 15196826 Effects of Periadolescent Versus Adult Cocaine Exposure on Cocaine Conditioned Place Preference and Motor Sensitization in Mice Psychopharmacology. Apr, 2004 | Pubmed ID: 14712337 Rap1 Couples CAMP Signaling to a Distinct Pool of P42/44MAPK Regulating Excitability, Synaptic Plasticity, Learning, and Memory Neuron. Jul, 2003 | Pubmed ID: 12873387 NMDA and Beta1-adrenergic Receptors Differentially Signal Phosphorylation of Glutamate Receptor Type 1 in Area CA1 of Hippocampus The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2003 | Pubmed ID: 12843287 Dorsal and Ventral Distribution of Excitable and Synaptic Properties of Neurons of the Bed Nucleus of the Stria Terminalis Journal of Neurophysiology. Jul, 2003 | Pubmed ID: 12649311 Synaptic Plasticity in Drug Reward Circuitry Current Molecular Medicine. Nov, 2002 | Pubmed ID: 12420805 LTP in the Mouse Nucleus Accumbens is Developmentally Regulated Synapse (New York, N.Y.). Sep, 2002 | Pubmed ID: 12125042 ERK Activation by G-protein-coupled Receptors in Mouse Brain is Receptor Identity-specific The Journal of Biological Chemistry. Mar, 2002 | Pubmed ID: 11782465 Operante Sensation Seeking in de muis Christopher M. Olsen1, Danny G. Winder1 1Department of Molecular Physiology and Biophysics, Center for Molecular Neuroscience, Kennedy Center for Human Development, Vanderbilt University Medical Center JoVE 2292 Neuroscience
Operante Sensation Seeking in de muis Christopher M. Olsen1, Danny G. Winder1 1Department of Molecular Physiology and Biophysics, Center for Molecular Neuroscience, Kennedy Center for Human Development, Vanderbilt University Medical Center JoVE 2292 Neuroscience