David C. Muddiman W. M. Keck FTMS Laboratory for Human Health Research, Department of Chemistry North Carolina State University Biography Publications Institution JoVE Articles David C. Muddiman has not added a biography. If you are David C. Muddiman and would like to personalize this page please email our Author Liaison for assistance. Publications Optimizing Mass Spectrometry Analyses: A Tailored Review on the Utility of Design of Experiments Journal of the American Society for Mass Spectrometry. Mar, 2016 | Pubmed ID: 26951559 TransOmic Analysis of Forebrain Sections in Sp2 Conditional Knockout Embryonic Mice Using IR-MALDESI Imaging of Lipids and LC-MS/MS Label-free Proteomics Analytical and Bioanalytical Chemistry. Mar, 2016 | Pubmed ID: 26942738 Wall Modified Photonic Crystal Fibre Capillaries As Porous Layer Open Tubular Columns for In-capillary Micro-extraction and Capillary Chromatography Analytica Chimica Acta. Jan, 2016 | Pubmed ID: 26755132 Analysis of Antiretrovirals in Single Hair Strands for Evaluation of Drug Adherence with Infrared-Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry Imaging Analytical Chemistry. Jan, 2016 | Pubmed ID: 26688545 What if You Could Only Publish 50 Papers Your Entire Career? Analytical and Bioanalytical Chemistry. Jan, 2016 | Pubmed ID: 26677017 Polarity Switching Mass Spectrometry Imaging of Healthy and Cancerous Hen Ovarian Tissue Sections by Infrared Matrix-assisted Laser Desorption Electrospray Ionization (IR-MALDESI) The Analyst. Jan, 2016 | Pubmed ID: 26402586 Mechanisms of Egg Yolk Formation and Implications on Early Life History of White Perch (Morone Americana) PloS One. 2015 | Pubmed ID: 26580971 Influence of C-Trap Ion Accumulation Time on the Detectability of Analytes in IR-MALDESI MSI Analytical Chemistry. Oct, 2015 | Pubmed ID: 26414177 Relative Quantification and Higher-Order Modeling of the Plasma Glycan Cancer Burden Ratio in Ovarian Cancer Case-Control Samples Journal of Proteome Research. Oct, 2015 | Pubmed ID: 26347193 Elucidation of Xylem-Specific Transcription Factors and Absolute Quantification of Enzymes Regulating Cellulose Biosynthesis in Populus Trichocarpa Journal of Proteome Research. Oct, 2015 | Pubmed ID: 26325666 Global Proteomic Analysis of Functional Compartments in Immature Avian Follicles Using Laser Microdissection Coupled to LC-MS/MS Journal of Proteome Research. Sep, 2015 | Pubmed ID: 26211554 In-depth LC-MS/MS Analysis of the Chicken Ovarian Cancer Proteome Reveals Conserved and Novel Differentially Regulated Proteins in Humans Analytical and Bioanalytical Chemistry. Sep, 2015 | Pubmed ID: 26159569 Phosphorylation is an On/off Switch for 5-hydroxyconiferaldehyde O-methyltransferase Activity in Poplar Monolignol Biosynthesis Proceedings of the National Academy of Sciences of the United States of America. Jul, 2015 | Pubmed ID: 26109572 Definitive Screening Design Optimization of Mass Spectrometry Parameters for Sensitive Comparison of Filter and Solid Phase Extraction Purified, INLIGHT Plasma N-Glycans Analytical Chemistry. Jul, 2015 | Pubmed ID: 26086806 Assessing Drug and Metabolite Detection in Liver Tissue by UV-MALDI and IR-MALDESI Mass Spectrometry Imaging Coupled to FT-ICR MS International Journal of Mass Spectrometry. Feb, 2015 | Pubmed ID: 26056514 Phosphoproteome Analysis Links Protein Phosphorylation to Cellular Remodeling and Metabolic Adaptation During Magnaporthe Oryzae Appressorium Development Journal of Proteome Research. Jun, 2015 | Pubmed ID: 25926025 Machine Learning Reveals Sex-specific 17β-estradiol-responsive Expression Patterns in White Perch (Morone Americana) Plasma Proteins Proteomics. Aug, 2015 | Pubmed ID: 25900664 Influence of Desorption Conditions on Analyte Sensitivity and Internal Energy in Discrete Tissue or Whole Body Imaging by IR-MALDESI Journal of the American Society for Mass Spectrometry. Jun, 2015 | Pubmed ID: 25840812 Mass Spectrometry Imaging Reveals Heterogeneous Efavirenz Distribution Within Putative HIV Reservoirs Antimicrobial Agents and Chemotherapy. May, 2015 | Pubmed ID: 25733502 Activin/nodal Signaling Switches the Terminal Fate of Human Embryonic Stem Cell-derived Trophoblasts The Journal of Biological Chemistry. Apr, 2015 | Pubmed ID: 25670856 4-Coumaroyl and Caffeoyl Shikimic Acids Inhibit 4-coumaric Acid:coenzyme A Ligases and Modulate Metabolic Flux for 3-hydroxylation in Monolignol Biosynthesis of Populus Trichocarpa Molecular Plant. Jan, 2015 | Pubmed ID: 25578281 Michael Gross: 25 Years of Dedication and Leadership of JASMS (1990-2015) Journal of the American Society for Mass Spectrometry. Jan, 2015 | Pubmed ID: 25537473 Cellular-level Mass Spectrometry Imaging Using Infrared Matrix-assisted Laser Desorption Electrospray Ionization (IR-MALDESI) by Oversampling Analytical and Bioanalytical Chemistry. Mar, 2015 | Pubmed ID: 25486925 Quantitative Mass Spectrometry Imaging of Emtricitabine in Cervical Tissue Model Using Infrared Matrix-assisted Laser Desorption Electrospray Ionization Analytical and Bioanalytical Chemistry. Mar, 2015 | Pubmed ID: 25318460 Analysis of Trace Fibers by IR-MALDESI Imaging Coupled with High Resolving Power MS Analytical and Bioanalytical Chemistry. Jan, 2015 | Pubmed ID: 25081013 C/EBPα Regulates CRL4(Cdt2)-mediated Degradation of P21 in Response to UVB-induced DNA Damage to Control the G1/S Checkpoint Cell Cycle (Georgetown, Tex.). 2014 | Pubmed ID: 25483090 Evaluating Nonpolar Surface Area and Liquid Chromatography/mass Spectrometry Response: an Application for Site Occupancy Measurements for Enzyme Intermediates in Polyketide Biosynthesis Rapid Communications in Mass Spectrometry : RCM. Dec, 2014 | Pubmed ID: 25366398 4-Coumaroyl and Caffeoyl Shikimic Acids Inhibit 4-Coumaric Acid: Coenzyme A Ligases and Modulate Metabolic Flux for 3-Hydroxylation in Monolignol Biosynthesis of Populus Trichocarpa Molecular Plant. Oct, 2014 | Pubmed ID: 25336570 Focus on Advancing High Performance Mass Spectrometry, Honoring Dr. Richard D. Smith, Recipient of the 2013 Award for a Distinguished Contribution in Mass Spectrometry Journal of the American Society for Mass Spectrometry. Dec, 2014 | Pubmed ID: 25326057 Silver Dopants for Targeted and Untargeted Direct Analysis of Unsaturated Lipids Via Infrared Matrix-assisted Laser Desorption Electrospray Ionization (IR-MALDESI) Rapid Communications in Mass Spectrometry : RCM. Nov, 2014 | Pubmed ID: 25303475 Establishing Ion Ratio Thresholds Based on Absolute Peak Area for Absolute Protein Quantification Using Protein Cleavage Isotope Dilution Mass Spectrometry The Analyst. Nov, 2014 | Pubmed ID: 25154770 Hierarchical Self-assembly of Supramolecular Hydrophobic Metallacycles into Ordered Nanostructures Chemistry, an Asian Journal. Oct, 2014 | Pubmed ID: 25139814 Mapping Antiretroviral Drugs in Tissue by IR-MALDESI MSI Coupled to the Q Exactive and Comparison with LC-MS/MS SRM Assay Journal of the American Society for Mass Spectrometry. Dec, 2014 | Pubmed ID: 24744212 Systems Biology of Lignin Biosynthesis in Populus Trichocarpa: Heteromeric 4-coumaric Acid:coenzyme A Ligase Protein Complex Formation, Regulation, and Numerical Modeling The Plant Cell. Mar, 2014 | Pubmed ID: 24619612 Complete Proteomic-based Enzyme Reaction and Inhibition Kinetics Reveal How Monolignol Biosynthetic Enzyme Families Affect Metabolic Flux and Lignin in Populus Trichocarpa The Plant Cell. Mar, 2014 | Pubmed ID: 24619611 Compartment Proteomics Analysis of White Perch (Morone Americana) Ovary Using Support Vector Machines Journal of Proteome Research. Mar, 2014 | Pubmed ID: 24494930 Are Presentations at ASMS Conferences Publications? Journal of the American Society for Mass Spectrometry. Mar, 2014 | Pubmed ID: 24385401 IR-MALDESI Mass Spectrometry Imaging of Biological Tissue Sections Using Ice As a Matrix Journal of the American Society for Mass Spectrometry. Mar, 2014 | Pubmed ID: 24385399 Reply to the Comment On: "Utilizing Artificial Neural Networks in MATLAB to Achieve Parts-per-billion Mass Measurement Accuracy with a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer" by D. Keith Williams Jr., Alexander L. Kovach, David C. Muddiman, and Kenneth W. Hanck. J. Am. Soc. Mass Spectrom. 20, 1303-1310 (2009) Journal of the American Society for Mass Spectrometry. Apr, 2014 | Pubmed ID: 24363170 Accurate Identification of Deamidated Peptides in Global Proteomics Using a Quadrupole Orbitrap Mass Spectrometer Journal of Proteome Research. Feb, 2014 | Pubmed ID: 24289162 Understanding the Role of Proteolytic Digestion on Discovery and Targeted Proteomic Measurements Using Liquid Chromatography Tandem Mass Spectrometry and Design of Experiments Journal of Proteome Research. Dec, 2013 | Pubmed ID: 24144163 Factorial Experimental Designs Elucidate Significant Variables Affecting Data Acquisition on a Quadrupole Orbitrap Mass Spectrometer Journal of the American Society for Mass Spectrometry. Oct, 2013 | Pubmed ID: 23913023 Individuality Normalization when Labeling with Isotopic Glycan Hydrazide Tags (INLIGHT): a Novel Glycan-relative Quantification Strategy Journal of the American Society for Mass Spectrometry. Sep, 2013 | Pubmed ID: 23860851 Regulation of Phenylalanine Ammonia-lyase (PAL) Gene Family in Wood Forming Tissue of Populus Trichocarpa Planta. Sep, 2013 | Pubmed ID: 23765265 Mass Recalibration of FT-ICR Mass Spectrometry Imaging Data Using the Average Frequency Shift of Ambient Ions Journal of the American Society for Mass Spectrometry. Jul, 2013 | Pubmed ID: 23715870 The Use of a Xylosylated Plant Glycoprotein As an Internal Standard Accounting for N-linked Glycan Cleavage and Sample Preparation Variability Rapid Communications in Mass Spectrometry : RCM. Jun, 2013 | Pubmed ID: 23681813 Temporal Analysis of the Magnaporthe Oryzae Proteome During Conidial Germination and Cyclic AMP (cAMP)-mediated Appressorium Formation Molecular & Cellular Proteomics : MCP. Aug, 2013 | Pubmed ID: 23665591 Multi-peptide NLC-PC-IDMS-SRM-based Assay for the Quantification of Biomarkers in the Chicken Ovarian Cancer Model Methods (San Diego, Calif.). Jun, 2013 | Pubmed ID: 23603217 MSiReader: an Open-source Interface to View and Analyze High Resolving Power MS Imaging Files on Matlab Platform Journal of the American Society for Mass Spectrometry. May, 2013 | Pubmed ID: 23536269 Comparative Proteomic Analysis and IgE Binding Properties of Peanut Seed and Testa (skin) Journal of Agricultural and Food Chemistry. Apr, 2013 | Pubmed ID: 23534881 Monolignol Pathway 4-coumaric Acid:coenzyme A Ligases in Populus Trichocarpa: Novel Specificity, Metabolic Regulation, and Simulation of Coenzyme A Ligation Fluxes Plant Physiology. Mar, 2013 | Pubmed ID: 23344904 Direct Analysis of Textile Fabrics and Dyes Using Infrared Matrix-assisted Laser Desorption Electrospray Ionization Mass Spectrometry Analytical Chemistry. Jan, 2013 | Pubmed ID: 23237031 Infrared Matrix-assisted Laser Desorption Electrospray Ionization (IR-MALDESI) Imaging Source Coupled to a FT-ICR Mass Spectrometer Journal of the American Society for Mass Spectrometry. Jan, 2013 | Pubmed ID: 23208743 Poly-specific Trans-acyltransferase Machinery Revealed Via Engineered Acyl-CoA Synthetases ACS Chemical Biology. Oct, 2012 | Pubmed ID: 23083014 In-depth Analysis of the Magnaporthe Oryzae Conidial Proteome Journal of Proteome Research. Dec, 2012 | Pubmed ID: 23039028 Targeted Proteomics of the Secretory Pathway Reveals the Secretome of Mouse Embryonic Fibroblasts and Human Embryonic Stem Cells Molecular & Cellular Proteomics : MCP. Dec, 2012 | Pubmed ID: 22984290 Systematic Comparison of Reverse Phase and Hydrophilic Interaction Liquid Chromatography Platforms for the Analysis of N-linked Glycans Analytical Chemistry. Oct, 2012 | Pubmed ID: 22954204 Polyubiquitin is Required for Growth, Development and Pathogenicity in the Rice Blast Fungus Magnaporthe Oryzae PloS One. 2012 | Pubmed ID: 22900059 Functional Redundancy of the Two 5-hydroxylases in Monolignol Biosynthesis of Populus Trichocarpa: LC-MS/MS Based Protein Quantification and Metabolic Flux Analysis Planta. Sep, 2012 | Pubmed ID: 22628084 Peptide Production and Decay Rates Affect the Quantitative Accuracy of Protein Cleavage Isotope Dilution Mass Spectrometry (PC-IDMS) Molecular & Cellular Proteomics : MCP. Sep, 2012 | Pubmed ID: 22595788 Comprehensive Quantification of Monolignol-pathway Enzymes in Populus Trichocarpa by Protein Cleavage Isotope Dilution Mass Spectrometry Journal of Proteome Research. Jun, 2012 | Pubmed ID: 22524869 High-resolution Mass Spectrometry Analytical and Bioanalytical Chemistry. May, 2012 | Pubmed ID: 22488110 The Subcellular Proteome of Undifferentiated Human Embryonic Stem Cells Proteomics. Feb, 2012 | Pubmed ID: 22144211 Absolute Quantification of Free Glutathione and Cysteine in Aquatic Insects Using Isotope Dilution and Selected Reaction Monitoring Analytical and Bioanalytical Chemistry. Jan, 2012 | Pubmed ID: 21956263 Membrane Protein Complexes Catalyze Both 4- and 3-hydroxylation of Cinnamic Acid Derivatives in Monolignol Biosynthesis Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22160716 Global Optimization of the Infrared Matrix-assisted Laser Desorption Electrospray Ionization (IR MALDESI) Source for Mass Spectrometry Using Statistical Design of Experiments Rapid Communications in Mass Spectrometry : RCM. Dec, 2011 | Pubmed ID: 22095501 Hydrophobic Derivatization of N-linked Glycans for Increased Ion Abundance in Electrospray Ionization Mass Spectrometry Journal of the American Society for Mass Spectrometry. Aug, 2011 | Pubmed ID: 21953184 Spectral Accuracy and Sulfur Counting Capabilities of the LTQ-FT-ICR and the LTQ-Orbitrap XL for Small Molecule Analysis Journal of the American Society for Mass Spectrometry. Dec, 2011 | Pubmed ID: 21952785 Evaluation of Normalization Methods on GeLC-MS/MS Label-free Spectral Counting Data to Correct for Variation During Proteomic Workflows Journal of the American Society for Mass Spectrometry. Dec, 2011 | Pubmed ID: 21952779 N-linked Global Glycan Profiling by NanoLC Mass Spectrometry Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21948408 One-Year Plasma N-linked Glycome Intra-individual and Inter-individual Variability in the Chicken Model of Spontaneous Ovarian Adenocarcinoma International Journal of Mass Spectrometry. Aug, 2011 | Pubmed ID: 21845070 Comparison of Stable-isotope Labeling with Amino Acids in Cell Culture and Spectral Counting for Relative Quantification of Protein Expression Rapid Communications in Mass Spectrometry : RCM. Sep, 2011 | Pubmed ID: 21818813 Stable-isotope Labeled Hydrophobic Hydrazide Reagents for the Relative Quantification of N-linked Glycans by Electrospray Ionization Mass Spectrometry Analytical Chemistry. Sep, 2011 | Pubmed ID: 21774516 Identification of Alternative Splice Variants in Aspergillus Flavus Through Comparison of Multiple Tandem MS Search Algorithms BMC Genomics. 2011 | Pubmed ID: 21745387 Capitalizing on the Hydrophobic Bias of Electrospray Ionization Through Chemical Modification in Mass Spectrometry-based Proteomics Expert Review of Proteomics. Jun, 2011 | Pubmed ID: 21679113 Performance Characteristics of a New Hybrid Quadrupole Time-of-flight Tandem Mass Spectrometer (TripleTOF 5600) Analytical Chemistry. Jul, 2011 | Pubmed ID: 21619048 Design, Modeling, Fabrication, and Evaluation of the Air Amplifier for Improved Detection of Biomolecules by Electrospray Ionization Mass Spectrometry International Journal of Mass Spectrometry. Mar, 2011 | Pubmed ID: 21499524 Improving Proteome Coverage on a LTQ-Orbitrap Using Design of Experiments Journal of the American Society for Mass Spectrometry. Apr, 2011 | Pubmed ID: 21472614 Increasing Proteome Coverage with Offline RP HPLC Coupled to Online RP NanoLC-MS Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Mar, 2011 | Pubmed ID: 21342794 Retrospective. John Bennett Fenn (1917-2010) Science (New York, N.Y.). Jan, 2011 | Pubmed ID: 21233376 Utilizing Spectral Counting to Quantitatively Characterize Tandem Removal of Abundant Proteins (TRAP) in Human Plasma Analytical Chemistry. Dec, 2010 | Pubmed ID: 21090636 Self-assembly of Dendritic Tris(crown Ether) Hexagons and Their Complexation with Dibenzylammonium Cations The Journal of Organic Chemistry. Nov, 2010 | Pubmed ID: 20879776 Direct Comparison of Stable Isotope Labeling by Amino Acids in Cell Culture and Spectral Counting for Quantitative Proteomics Analytical Chemistry. Oct, 2010 | Pubmed ID: 20845935 Measuring the Intra-individual Variability of the Plasma Proteome in the Chicken Model of Spontaneous Ovarian Adenocarcinoma Analytical and Bioanalytical Chemistry. Sep, 2010 | Pubmed ID: 20640409 Interplay of Permanent Charge and Hydrophobicity in the Electrospray Ionization of Glycans Analytical Chemistry. Aug, 2010 | Pubmed ID: 20590124 Study of the Ionization Mechanism in Hybrid Laser Based Desorption Techniques The Analyst. May, 2010 | Pubmed ID: 20419234 Quantitative Top-down Proteomics of SILAC Labeled Human Embryonic Stem Cells Journal of the American Society for Mass Spectrometry. Jun, 2010 | Pubmed ID: 20199872 The Effects of Abundant Plasma Protein Depletion on Global Glycan Profiling Using NanoLC FT-ICR Mass Spectrometry Analytical and Bioanalytical Chemistry. Feb, 2010 | Pubmed ID: 20087731 Binding Site on Human Immunoglobulin G for the Affinity Ligand HWRGWV Journal of Molecular Recognition : JMR. May-Jun, 2010 | Pubmed ID: 20049844 Detection of Alternative Splice Variants at the Proteome Level in Aspergillus Flavus Journal of Proteome Research. Mar, 2010 | Pubmed ID: 20047314 Increasing the Hydrophobicity and Electrospray Response of Glycans Through Derivatization with Novel Cationic Hydrazides Chemical Communications (Cambridge, England). Jan, 2010 | Pubmed ID: 20024337 Improving Limits of Detection for B-type Natriuretic Peptide Using PC-IDMS: an Application of the ALiPHAT Strategy The Analyst. Jan, 2010 | Pubmed ID: 20024179 Mass Spectrometry-based Biomarker Discovery: Toward a Global Proteome Index of Individuality Annual Review of Analytical Chemistry (Palo Alto, Calif.). 2009 | Pubmed ID: 20636062 Tandem Mass Spectrometry of Thiolate-protected Au Nanoparticles Na(x)Au25(SC2H4Ph)(18-y)(S(C2H4O)5CH3)(y) Journal of the American Chemical Society. Sep, 2009 | Pubmed ID: 19736992 Evaluation of the ALiPHAT Method for PC-IDMS and Correlation of Limits-of-detection with Nonpolar Surface Area Journal of the American Society for Mass Spectrometry. Nov, 2009 | Pubmed ID: 19734056 Proteomics Characterization of Cell Membrane Blebs in Human Retinal Pigment Epithelium Cells Molecular & Cellular Proteomics : MCP. Oct, 2009 | Pubmed ID: 19567368 Characterization of Charge Separation in the Array of Micromachined UltraSonic Electrospray (AMUSE) Ion Source for Mass Spectrometry Journal of the American Society for Mass Spectrometry. Sep, 2009 | Pubmed ID: 19525123 Atmospheric Pressure Infrared (10.6 Microm) Laser Desorption Electrospray Ionization (IR-LDESI) Coupled to a LTQ Fourier Transform Ion Cyclotron Resonance Mass Spectrometer Rapid Communications in Mass Spectrometry : RCM. Jul, 2009 | Pubmed ID: 19504481 Development of a Robust and High Throughput Method for Profiling N-linked Glycans Derived from Plasma Glycoproteins by NanoLC-FTICR Mass Spectrometry Journal of Proteome Research. Jul, 2009 | Pubmed ID: 19435342 Utilizing Artificial Neural Networks in MATLAB to Achieve Parts-per-billion Mass Measurement Accuracy with a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer Journal of the American Society for Mass Spectrometry. Jul, 2009 | Pubmed ID: 19362012 Synthesis of Six-component Metallodendrimers Via [3 + 3] Coordination-driven Self-assembly The Journal of Organic Chemistry. May, 2009 | Pubmed ID: 19344131 Coupling of a Vented Column with Splitless NanoRPLC-ESI-MS for the Improved Separation and Detection of Brain Natriuretic Peptide-32 and Its Proteolytic Peptides Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Apr, 2009 | Pubmed ID: 19269262 Absolute Quantification of C-reactive Protein in Human Plasma Derived from Patients with Epithelial Ovarian Cancer Utilizing Protein Cleavage Isotope Dilution Mass Spectrometry Journal of Proteome Research. Feb, 2009 | Pubmed ID: 19196186 Intact and Top-down Characterization of Biomolecules and Direct Analysis Using Infrared Matrix-assisted Laser Desorption Electrospray Ionization Coupled to FT-ICR Mass Spectrometry Journal of the American Society for Mass Spectrometry. Apr, 2009 | Pubmed ID: 19185512 Development of a NanoLC LTQ Orbitrap Mass Spectrometric Method for Profiling Glycans Derived from Plasma from Healthy, Benign Tumor Control, and Epithelial Ovarian Cancer Patients Analytical Chemistry. Feb, 2009 | Pubmed ID: 19113831 Generation of Multiply Charged Peptides and Proteins by Radio Frequency Acoustic Desorption and Ionization for Mass Spectrometric Detection Journal of the American Society for Mass Spectrometry. Apr, 2009 | Pubmed ID: 19112029 Construction of a Versatile High Precision Ambient Ionization Source for Direct Analysis and Imaging Journal of the American Society for Mass Spectrometry. Oct, 2008 | Pubmed ID: 18657438 Development and Characterization of an Ionization Technique for Analysis of Biological Macromolecules: Liquid Matrix-assisted Laser Desorption Electrospray Ionization Analytical Chemistry. Sep, 2008 | Pubmed ID: 18656949 Calibration Laws Based on Multiple Linear Regression Applied to Matrix-assisted Laser Desorption/ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Journal of Mass Spectrometry : JMS. Dec, 2008 | Pubmed ID: 18563853 Temperature-dependent Regulation of Proteins in Aspergillus Flavus: Whole Organism Stable Isotope Labeling by Amino Acids Journal of Proteome Research. Jul, 2008 | Pubmed ID: 18529071 Ambient Aerodynamic Ionization Source for Remote Analyte Sampling and Mass Spectrometric Analysis Analytical Chemistry. Jul, 2008 | Pubmed ID: 18529018 Top-down Identification and Quantification of Stable Isotope Labeled Proteins from Aspergillus Flavus Using Online Nano-flow Reversed-phase Liquid Chromatography Coupled to a LTQ-FTICR Mass Spectrometer Analytical Chemistry. Jul, 2008 | Pubmed ID: 18512951 Coordination-driven Face-directed Self-assembly of Trigonal Prisms. Face-based Conformational Chirality Journal of the American Chemical Society. Jun, 2008 | Pubmed ID: 18491898 Effect of Plasma Protein Depletion on BNP-32 Recovery Clinical Chemistry. May, 2008 | Pubmed ID: 18443186 Studying O-linked Protein Glycosylations in Human Plasma Journal of Proteome Research. Jun, 2008 | Pubmed ID: 18422354 Mass Measurement Accuracy Comparisons Between a Double-focusing Magnetic Sector and a Time-of-flight Mass Analyzer Rapid Communications in Mass Spectrometry : RCM. May, 2008 | Pubmed ID: 18421754 Coordination-driven Self-assembly of Cavity-cored Multiple Crown Ether Derivatives and Poly[2]pseudorotaxanes Journal of the American Chemical Society. Apr, 2008 | Pubmed ID: 18341280 Investigations with O-linked Protein Glycosylations by Matrix-assisted Laser Desorption/ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Journal of Mass Spectrometry : JMS. Sep, 2008 | Pubmed ID: 18324610 Human Proteinpedia Enables Sharing of Human Protein Data Nature Biotechnology. Feb, 2008 | Pubmed ID: 18259167 Synthesis, Characterization, and Application of Iodoacetamide Derivatives Utilized for the ALiPHAT Strategy Journal of the American Chemical Society. Feb, 2008 | Pubmed ID: 18220392 A New Family of Multiferrocene Complexes with Enhanced Control of Structure and Stoichiometry Via Coordination-driven Self-assembly and Their Electrochemistry Journal of the American Chemical Society. Jan, 2008 | Pubmed ID: 18166061 A Highly Efficient Approach to the Self-assembly of Hexagonal Cavity-cored Tris[2]pseudorotaxanes from Several Components Via Multiple Noncovalent Interactions Journal of the American Chemical Society. Nov, 2007 | Pubmed ID: 17963382 Carbohydrate Analysis by Desorption Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Analytical Chemistry. Nov, 2007 | Pubmed ID: 17918969 Dual Electrospray Ion Source for Electron-transfer Dissociation on a Hybrid Linear Ion Trap-orbitrap Mass Spectrometer Analytical Chemistry. Oct, 2007 | Pubmed ID: 17867655 Probing the Mechanisms of an Air Amplifier Using a LTQ-FT-ICR-MS and Fluorescence Spectroscopy Journal of the American Society for Mass Spectrometry. Nov, 2007 | Pubmed ID: 17855111 Differential Protein Expression in Male and Female Human Lumbar Cerebrospinal Fluid Using ITRAQ Reagents After Abundant Protein Depletion Proteomics. Oct, 2007 | Pubmed ID: 17853512 Quantitative Comparison of a Flared and a Standard Heated Metal Capillary Inlet with a Voltage-assisted Air Amplifier on an Electrospray Ionization Linear Ion Trap Mass Spectrometer Rapid Communications in Mass Spectrometry : RCM. 2007 | Pubmed ID: 17764103 Details of the Structure Determination of the Sulfated Steroids PSDS and PADS: New Components of the Sea Lamprey (petromyzon Marinus) Migratory Pheromone The Journal of Organic Chemistry. Sep, 2007 | Pubmed ID: 17718505 Remote Mass Spectrometric Sampling of Electrospray- and Desorption Electrospray-generated Ions Using an Air Ejector Journal of the American Society for Mass Spectrometry. Oct, 2007 | Pubmed ID: 17716909 Epithelial Ovarian Cancer: Disease Etiology, Treatment, Detection, and Investigational Gene, Metabolite, and Protein Biomarkers Journal of Proteome Research. Aug, 2007 | Pubmed ID: 17583933 Parts-per-billion Mass Measurement Accuracy Achieved Through the Combination of Multiple Linear Regression and Automatic Gain Control in a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer Analytical Chemistry. Jul, 2007 | Pubmed ID: 17539605 Detection of Attomole Amounts of Analyte by Desorption Electrospray Ionization Mass Spectrometry (DESI-MS) Determined Using Fluorescence Spectroscopy Journal of the American Society for Mass Spectrometry. Jun, 2007 | Pubmed ID: 17448675 Understanding the Influence of Post-excite Radius and Axial Confinement on Quantitative Proteomic Measurements Using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Rapid Communications in Mass Spectrometry : RCM. 2007 | Pubmed ID: 17330212 Direct Characterization of Intact Polypeptides by Matrix-assisted Laser Desorption Electrospray Ionization Quadrupole Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Rapid Communications in Mass Spectrometry : RCM. 2007 | Pubmed ID: 17318926 Effect of Matrix Crystal Structure on Ion Abundance of Carbohydrates by Matrix-assisted Laser Desorption/ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Rapid Communications in Mass Spectrometry : RCM. 2007 | Pubmed ID: 17279479 Coordination-driven Self-assembly of Metallodendrimers Possessing Well-defined and Controllable Cavities As Cores Journal of the American Chemical Society. Feb, 2007 | Pubmed ID: 17256935 A Method for Automatically Interpreting Mass Spectra of 18O-labeled Isotopic Clusters Molecular & Cellular Proteomics : MCP. Feb, 2007 | Pubmed ID: 17068186 Sub Parts-per-million Mass Measurement Accuracy of Intact Proteins and Product Ions Achieved Using a Dual Electrospray Ionization Quadrupole Fourier Transform Ion Cyclotron Resonance Mass Spectrometer Journal of the American Society for Mass Spectrometry. Jan, 2007 | Pubmed ID: 16979902 Elevated Levels of Phosphorylated Fibrinogen-alpha-isoforms and Differential Expression of Other Post-translationally Modified Proteins in the Plasma of Ovarian Cancer Patients Journal of Proteome Research. Dec, 2006 | Pubmed ID: 17137333 Direct High-resolution Peptide and Protein Analysis by Desorption Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Rapid Communications in Mass Spectrometry : RCM. 2006 | Pubmed ID: 17051610 Generation and Detection of Multiply-charged Peptides and Proteins by Matrix-assisted Laser Desorption Electrospray Ionization (MALDESI) Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Journal of the American Society for Mass Spectrometry. Dec, 2006 | Pubmed ID: 16952462 Incorporation of 2,6-di(4,4'-dipyridyl)-9-thiabicyclo[3.3.1]nonane into Discrete 2D Supramolecules Via Coordination-driven Self-assembly The Journal of Organic Chemistry. Aug, 2006 | Pubmed ID: 16901162 Molecular Architecture Via Coordination: Self-assembly of Nanoscale Hexagonal Metallodendrimers with Designed Building Blocks Journal of the American Chemical Society. Aug, 2006 | Pubmed ID: 16881621 Accessible Proteomics Space and Its Implications for Peak Capacity for Zero-, One- and Two-dimensional Separations Coupled with FT-ICR and TOF Mass Spectrometry Journal of Mass Spectrometry : JMS. Mar, 2006 | Pubmed ID: 16538648 Chromatin Assembly Factor 1 Interacts with Histone H3 Methylated at Lysine 79 in the Processes of Epigenetic Silencing and DNA Repair Biochemistry. Mar, 2006 | Pubmed ID: 16503640 "Lewis and Clark" Proteomics Journal of Proteome Research. Feb, 2006 | Pubmed ID: 16502570 Identification of Subunit-subunit Interactions in Bacteriophage P22 Procapsids by Chemical Cross-linking and Mass Spectrometry Journal of Proteome Research. Feb, 2006 | Pubmed ID: 16457603 Reproducibility of Retention Time Using a Splitless NanoLC Coupled to an ESI-FTICR Mass Spectrometer Journal of Biomolecular Techniques : JBT. Dec, 2005 | Pubmed ID: 16522864 Identification of Class II HLA-DRB1*03-bound Measles Virus Peptides by 2D-liquid Chromatography Tandem Mass Spectrometry Journal of Proteome Research. Nov-Dec, 2005 | Pubmed ID: 16335972 Quantitative Mass Spectral Evidence for the Absence of Circulating Brain Natriuretic Peptide (BNP-32) in Severe Human Heart Failure Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005 | Pubmed ID: 16293687 Gentle Protein Ionization Assisted by High-velocity Gas Flow Analytical Chemistry. Oct, 2005 | Pubmed ID: 16194076 Accurate Mass Precursor Ion Data and Tandem Mass Spectrometry Identify a Class I Human Leukocyte Antigen A*0201-presented Peptide Originating from Vaccinia Virus Journal of the American Society for Mass Spectrometry. Nov, 2005 | Pubmed ID: 16185891 Normalization of Relative Peptide Ratios Derived from In-gel Digests: Applications to Protein Variant Analysis at the Peptide Level Rapid Communications in Mass Spectrometry : RCM. 2005 | Pubmed ID: 16155979 Coordination-driven Self-assemblies with a Carborane Backbone Journal of the American Chemical Society. Aug, 2005 | Pubmed ID: 16117555 Quantitative Protein Expression Analysis of CLL B Cells from Mutated and Unmutated IgV(H) Subgroups Using Acid-cleavable Isotope-coded Affinity Tag Reagents Journal of Proteome Research. Jul-Aug, 2005 | Pubmed ID: 16083281 Primary Trabecular Meshwork Cells Incubated in Human Aqueous Humor Differ from Cells Incubated in Serum Supplements Investigative Ophthalmology & Visual Science. Aug, 2005 | Pubmed ID: 16043859 Déjà Vu All over Again: Skin Cap Still Contains a High-potency Glucocorticosteroid Archives of Dermatology. Jun, 2005 | Pubmed ID: 15967944 Evaluation of Protein Depletion Methods for the Analysis of Total-, Phospho- and Glycoproteins in Lumbar Cerebrospinal Fluid Journal of Proteome Research. May-Jun, 2005 | Pubmed ID: 15952730 Leveling Response Factors in the Electrospray Ionization Process Using a Heated Capillary Interface Journal of the American Society for Mass Spectrometry. May, 2005 | Pubmed ID: 15862778 Statistical Evaluation of Internal and External Mass Calibration Laws Utilized in Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Analytical Chemistry. Apr, 2005 | Pubmed ID: 15828774 Mapping Sites of Protein Phosphorylation by Mass Spectrometry Utilizing a Chemical-enzymatic Approach: Characterization of Products from Alpha-S1 Casein Phosphopeptides Journal of Proteome Research. Mar-Apr, 2005 | Pubmed ID: 15822919 Protein Expression Profiling of CLL B Cells Using Replicate Off-line Strong Cation Exchange Chromatography and LC-MS/MS Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. May, 2005 | Pubmed ID: 15797518 Effect of Post-excitation Radius on Ion Abundance, Mass Measurement Accuracy, and Isotopic Distributions in Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Rapid Communications in Mass Spectrometry : RCM. 2005 | Pubmed ID: 15747331 Analysis of the Low Molecular Weight Fraction of Serum by LC-dual ESI-FT-ICR Mass Spectrometry: Precision of Retention Time, Mass, and Ion Abundance Analytical Chemistry. Sep, 2004 | Pubmed ID: 15373448 Analytical Performance of a Venturi Device Integrated into an Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometer for Analysis of Nucleic Acids Analytical Chemistry. Jul, 2004 | Pubmed ID: 15253651 Evaluation of a Cleavable Stable Isotope Labeled Synthetic Peptide for Absolute Protein Quantification Using LC-MS/MS Journal of Proteome Research. May-Jun, 2004 | Pubmed ID: 15253450 Absolute Quantification of the Model Biomarker Prostate-specific Antigen in Serum by LC-Ms/MS Using Protein Cleavage and Isotope Dilution Mass Spectrometry Journal of Proteome Research. May-Jun, 2004 | Pubmed ID: 15253448 Identification of Transthyretin Variants by Sequential Proteomic and Genomic Analysis Clinical Chemistry. Sep, 2004 | Pubmed ID: 15217993 Detection of Genetic Variants of Transthyretin by Liquid Chromatography-dual Electrospray Ionization Fourier-transform Ion-cyclotron-resonance Mass Spectrometry Clinical Chemistry. Sep, 2004 | Pubmed ID: 15205369 Informed Use of Proteolytic Inhibitors in Biomarker Discovery Rapid Communications in Mass Spectrometry : RCM. 2004 | Pubmed ID: 15116428 A Method for Calculating 16O/18O Peptide Ion Ratios for the Relative Quantification of Proteomes Journal of the American Society for Mass Spectrometry. Apr, 2004 | Pubmed ID: 15047049 Androgens Negatively Regulate Forkhead Transcription Factor FKHR (FOXO1) Through a Proteolytic Mechanism in Prostate Cancer Cells The Journal of Biological Chemistry. Apr, 2004 | Pubmed ID: 14726521 Determination of the Relative Energies of Activation for the Dissociation of Aromatic Versus Aliphatic Phosphopeptides by ESI-FTICR-MS and IRMPD Journal of the American Society for Mass Spectrometry. Jan, 2004 | Pubmed ID: 14698562 Identification and Characterization of Novel, Naturally Processed Measles Virus Class II HLA-DRB1 Peptides Journal of Virology. Jan, 2004 | Pubmed ID: 14671086 Discovery of Ovarian Cancer Biomarkers in Serum Using NanoLC Electrospray Ionization TOF and FT-ICR Mass Spectrometry Disease Markers. 2003-2004 | Pubmed ID: 15266667 Enzymatic Strategies for the Characterization of Nucleic Acids by Electrospray Ionization Mass Spectrometry Rapid Communications in Mass Spectrometry : RCM. 2003 | Pubmed ID: 14673816 Dual Electrospray Ionization Source for Confident Generation of Accurate Mass Tags Using Liquid Chromatography Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Analytical Chemistry. Jul, 2003 | Pubmed ID: 14570191 Naturally Processed Measles Virus Peptide Eluted from Class II HLA-DRB1*03 Recognized by T Lymphocytes from Human Blood Virology. Aug, 2003 | Pubmed ID: 12919753 Coordination-driven Self-assembly of Supramolecular Cages: Heteroatom-containing and Complementary Trigonal Prisms Journal of the American Chemical Society. Aug, 2003 | Pubmed ID: 12904031 Determination of a Correction to Improve Mass Measurement Accuracy of Isotopically Unresolved Polymerase Chain Reaction Amplicons by Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Rapid Communications in Mass Spectrometry : RCM. 2003 | Pubmed ID: 12872276 Mass Spectral Determination of Skeletal/cardiac Actin Isoform Ratios in Cardiac Muscle Rapid Communications in Mass Spectrometry : RCM. 2003 | Pubmed ID: 12820213 Advantages of Thermococcus Kodakaraenis (KOD) DNA Polymerase for PCR-mass Spectrometry Based Analyses Journal of the American Society for Mass Spectrometry. Jun, 2003 | Pubmed ID: 12781461 Implications of Hydrophobicity and Free Energy of Solvation for Characterization of Nucleic Acids by Electrospray Ionization Mass Spectrometry Analytical Chemistry. Mar, 2003 | Pubmed ID: 12659193 Dual-micro-ESI Source for Precise Mass Determination on a Quadrupole Time-of-flight Mass Spectrometer for Genomic and Proteomic Applications Analytical and Bioanalytical Chemistry. Aug, 2002 | Pubmed ID: 12185565 Gas-phase Ion Unimolecular Dissociation for Rapid Phosphopeptide Mapping by IRMPD in a Penning Ion Trap: an Energetically Favored Process Journal of the American Chemical Society. Jun, 2002 | Pubmed ID: 12047170 Evaluation of Sample Preparation Techniques for Mass Measurements of PCR Products Using ESI-FT-ICR Mass Spectrometry Journal of the American Society for Mass Spectrometry. Apr, 2002 | Pubmed ID: 11951971 Solution Composition and Thermal Denaturation for the Production of Single-stranded PCR Amplicons: Piperidine-induced Destabilization of the DNA Duplex? Journal of the American Society for Mass Spectrometry. Mar, 2002 | Pubmed ID: 11908803 Kızılötesi Matriks destekli lazer desorpsiyon Elektrosprey İyonizasyon tarafından tüm vücut Kütle Spektrometre Görüntüleme (IR-MALDESI) Milad Nazari1, Mark T. Bokhart1, David C. Muddiman1 1W. M. Keck FTMS Laboratory for Human Health Research, Department of Chemistry, North Carolina State University Bioengineering Nicel Glycomics ve Proteomik Kombine Arıtma Stratejisi Elizabeth S. Hecht*1, James P. McCord*1, David C. Muddiman1 1Department of Chemistry, North Carolina State University Chemistry
Kızılötesi Matriks destekli lazer desorpsiyon Elektrosprey İyonizasyon tarafından tüm vücut Kütle Spektrometre Görüntüleme (IR-MALDESI) Milad Nazari1, Mark T. Bokhart1, David C. Muddiman1 1W. M. Keck FTMS Laboratory for Human Health Research, Department of Chemistry, North Carolina State University Bioengineering
Nicel Glycomics ve Proteomik Kombine Arıtma Stratejisi Elizabeth S. Hecht*1, James P. McCord*1, David C. Muddiman1 1Department of Chemistry, North Carolina State University Chemistry