David M. Chenoweth Department of Chemistry, School of Arts and Sciences University of Pennsylvania Biography Publications Institution JoVE Articles David M. Chenoweth has not added a biography. If you are David M. Chenoweth and would like to personalize this page please email our Author Liaison for assistance. Publications PEARL-seq: A Photoaffinity Platform for the Analysis of Small Molecule-RNA Interactions ACS Chemical Biology. 09, 2020 | Pubmed ID: 32804474 Preface Methods in Enzymology. 2020 | Pubmed ID: 32713540 Rational Design of Small Molecule Fluorescent Probes for Biological Applications Organic & Biomolecular Chemistry. Aug, 2020 | Pubmed ID: 32691820 Nuclear Body Phase Separation Drives Telomere Clustering in ALT Cancer Cells Molecular Biology of the Cell. 08, 2020 | Pubmed ID: 32579423 Preface Methods in Enzymology. 2020 | Pubmed ID: 32560808 Quinoline-based Fluorescent Small Molecules for Live Cell Imaging Methods in Enzymology. 2020 | Pubmed ID: 32560804 Photoconvertible Diazaxanthilidene Dyes for Live Cell Imaging Methods in Enzymology. 2020 | Pubmed ID: 32475411 Preface Methods in Enzymology. 2020 | Pubmed ID: 32416924 Photoactivatable Trimethoprim-based Probes for Spatiotemporal Control of Biological Processes Methods in Enzymology. 2020 | Pubmed ID: 32416918 Halogen Bonding Facilitates Intersystem Crossing in Iodo-BODIPY Chromophores The Journal of Physical Chemistry Letters. Feb, 2020 | Pubmed ID: 31931562 Incorporation of Aza-Glycine into Collagen Peptides The Journal of Organic Chemistry. 02, 2020 | Pubmed ID: 31724856 Sterics and Stereoelectronics in Aza-Glycine: Impact of Aza-Glycine Preorganization in Triple Helical Collagen Journal of the American Chemical Society. 11, 2019 | Pubmed ID: 31603316 Aza-proline Effectively Mimics L-proline Stereochemistry in Triple Helical Collagen Chemical Science. Aug, 2019 | Pubmed ID: 31588264 Reversible Optogenetic Control of Protein Function and Localization Methods in Enzymology. 2019 | Pubmed ID: 31370933 A "Clickable" Photoconvertible Small Fluorescent Molecule As a Minimalist Probe for Tracking Individual Biomolecule Complexes Journal of the American Chemical Society. 02, 2019 | Pubmed ID: 30657670 Improving the Fluorescent Probe Acridonylalanine Through a Combination of Theory and Experiment Journal of Physical Organic Chemistry. Aug, 2018 | Pubmed ID: 30983696 The Mechanism of the Triple Aryne-tetrazine Reaction Cascade: Theory and Experiment Chemical Science. Oct, 2018 | Pubmed ID: 30542547 Variation in the Yaa Position of Collagen Peptides Containing AzaGlycine Chemical Communications (Cambridge, England). Oct, 2018 | Pubmed ID: 30288510 Reversible Control of Protein Localization in Living Cells Using a Photocaged-Photocleavable Chemical Dimerizer Journal of the American Chemical Society. 09, 2018 | Pubmed ID: 30196699 Protein Kinase R-like Endoplasmatic Reticulum Kinase is a Mediator of Stretch in Ventilator-induced Lung Injury Respiratory Research. Aug, 2018 | Pubmed ID: 30134920 Rational Design and Facile Synthesis of a Highly Tunable Quinoline-Based Fluorescent Small-Molecule Scaffold for Live Cell Imaging Journal of the American Chemical Society. 08, 2018 | Pubmed ID: 30028130 Optogenetic Manipulation of Mouse Oocytes Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29961261 Optogenetic Control of Mitosis with Photocaged Chemical Dimerizers Methods in Cell Biology. 2018 | Pubmed ID: 29804668 Optochemical Control of Protein Localization and Activity Within Cell-like Compartments Biochemistry. 05, 2018 | Pubmed ID: 29671583 Spindle Asymmetry Drives Non-Mendelian Chromosome Segregation Science (New York, N.Y.). 11, 2017 | Pubmed ID: 29097549 Ultrafast Solvation Dynamics and Vibrational Coherences of Halogenated Boron-Dipyrromethene Derivatives Revealed Through Two-Dimensional Electronic Spectroscopy Journal of the American Chemical Society. 10, 2017 | Pubmed ID: 28945085 Optogenetic Control of Kinetochore Function Nature Chemical Biology. Oct, 2017 | Pubmed ID: 28805800 Structural Basis for Aza-Glycine Stabilization of Collagen Journal of the American Chemical Society. 07, 2017 | Pubmed ID: 28650147 The Effects of Thioamide Backbone Substitution on Protein Stability: a Study in α-helical, β-sheet, and Polyproline II Helical Contexts Chemical Science. Apr, 2017 | Pubmed ID: 28553525 Shape Changing Thin Films Powered by DNA Hybridization Nature Nanotechnology. 01, 2017 | Pubmed ID: 27775726 Aryne Compatible Solvents Are Not Always Innocent Organic Letters. 08, 2016 | Pubmed ID: 27486792 DNA Island Formation on Binary Block Copolymer Vesicles Journal of the American Chemical Society. 08, 2016 | Pubmed ID: 27433782 General Solution for Stabilizing Triple Helical Collagen Journal of the American Chemical Society. 08, 2016 | Pubmed ID: 27410188 Modulation of the E. coli RpoH Temperature Sensor with Triptycene-Based Small Molecules Angewandte Chemie (International Ed. in English). 07, 2016 | Pubmed ID: 27240201 Electronic Interactions of I, I + 1 Dithioamides: Increased Fluorescence Quenching and Evidence for N-to-π* Interactions Chemical Communications (Cambridge, England). Jun, 2016 | Pubmed ID: 27229876 Bridgehead-Substituted Triptycenes for Discovery of Nucleic Acid Junction Binders Organic Letters. 05, 2016 | Pubmed ID: 27172288 Synthesis of 9-Substituted Triptycene Building Blocks for Solid-Phase Diversification and Nucleic Acid Junction Targeting Organic Letters. Mar, 2016 | Pubmed ID: 26886290 Synthesis and Properties of Lysosome-specific Photoactivatable Probes for Live-cell Imaging Chemical Science. Aug, 2015 | Pubmed ID: 28496967 Triple Aryne-Tetrazine Reaction Enabling Rapid Access to a New Class of Polyaromatic Heterocycles Chemical Science. 2015 | Pubmed ID: 26388984 Aza-Glycine Induces Collagen Hyperstability Journal of the American Chemical Society. Oct, 2015 | Pubmed ID: 26368649 Triptycene-based Small Molecules Modulate (CAG)·(CTG) Repeat Junctions Chemical Science. Aug, 2015 | Pubmed ID: 26366282 A Single Stereodynamic Center Modulates the Rate of Self-Assembly in a Biomolecular System Angewandte Chemie (International Ed. in English). Sep, 2015 | Pubmed ID: 26212926 Optogenetic Control of Organelle Transport Using a Photocaged Chemical Inducer of Dimerization Current Biology : CB. May, 2015 | Pubmed ID: 25989077 Photoelectrocyclization As an Activation Mechanism for Organelle-specific Live-cell Imaging Probes Angewandte Chemie (International Ed. in English). May, 2015 | Pubmed ID: 25950154 Localized Light-induced Protein Dimerization in Living Cells Using a Photocaged Dimerizer Nature Communications. Nov, 2014 | Pubmed ID: 25400104 Recognition of Nucleic Acid Junctions Using Triptycene-based Molecules Angewandte Chemie (International Ed. in English). Dec, 2014 | Pubmed ID: 25257803 Synthesis and Conformational Dynamics of the Reported Structure of Xylopyridine A Journal of the American Chemical Society. Jun, 2013 | Pubmed ID: 23742249 Expansion of the Genetic Alphabet: Unnatural Nucleobases and Their Applications Journal of Nucleic Acids. 2012 | Pubmed ID: 23316342 Chemical Dimerization-Induced Protein Condensates on Telomeres Rongwei Zhao1, David M. Chenoweth2, Huaiying Zhang1 1Department of Biological Sciences, Mellon College of Science, Carnegie Mellon University, 2Department of Chemistry, School of Arts and Sciences, University of Pennsylvania JoVE 62173 Biology
Chemical Dimerization-Induced Protein Condensates on Telomeres Rongwei Zhao1, David M. Chenoweth2, Huaiying Zhang1 1Department of Biological Sciences, Mellon College of Science, Carnegie Mellon University, 2Department of Chemistry, School of Arts and Sciences, University of Pennsylvania JoVE 62173 Biology