Deborah A. Howatt Saha Cardiovascular Research Center University of Kentucky Biography Publications Institution JoVE Articles Deborah A. Howatt has not added a biography. If you are Deborah A. Howatt and would like to personalize this page please email our Author Liaison for assistance. Publications Fibroblast Angiotensin II Type 1a Receptors Contribute to Angiotensin II-Induced Medial Hyperplasia in the Ascending Aorta Arteriosclerosis, Thrombosis, and Vascular Biology. Sep, 2015 | Pubmed ID: 26160957 Associations of ApoAI and ApoB-Containing Lipoproteins With AngII-Induced Abdominal Aortic Aneurysms in Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2015 | Pubmed ID: 26044581 Increasing Adipocyte Lipoprotein Lipase Improves Glucose Metabolism in High Fat Diet-induced Obesity The Journal of Biological Chemistry. May, 2015 | Pubmed ID: 25784555 Deficiency of Endogenous Acute-Phase Serum Amyloid A Protects ApoE-/- Mice From Angiotensin II-Induced Abdominal Aortic Aneurysm Formation Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2015 | Pubmed ID: 25745063 Cys18-Cys137 Disulfide Bond in Mouse Angiotensinogen Does Not Affect AngII-dependent Functions in Vivo Hypertension. Apr, 2015 | Pubmed ID: 25691624 Smooth Muscle Cell Deletion of Low-density Lipoprotein Receptor-related Protein 1 Augments Angiotensin II-induced Superior Mesenteric Arterial and Ascending Aortic Aneurysms Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2015 | Pubmed ID: 25395615 Angiotensin-converting Enzyme 2 Decreases Formation and Severity of Angiotensin II-induced Abdominal Aortic Aneurysms Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2014 | Pubmed ID: 25301841 Angiotensin II Induces Region-specific Medial Disruption During Evolution of Ascending Aortic Aneurysms The American Journal of Pathology. Sep, 2014 | Pubmed ID: 25038458 Scavenger Receptor BI and High-density Lipoprotein Regulate Thymocyte Apoptosis in Sepsis Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2014 | Pubmed ID: 24603680 Deficiency of Endogenous Acute Phase Serum Amyloid A Does Not Affect Atherosclerotic Lesions in Apolipoprotein E-deficient Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2014 | Pubmed ID: 24265416 Amlodipine Reduces AngII-induced Aortic Aneurysms and Atherosclerosis in Hypercholesterolemic Mice PloS One. 2013 | Pubmed ID: 24244746 Calpain-2 Compensation Promotes Angiotensin II-induced Ascending and Abdominal Aortic Aneurysms in Calpain-1 Deficient Mice PloS One. 2013 | Pubmed ID: 23977256 High Density Lipoprotein Protects Against Polymicrobe-induced Sepsis in Mice The Journal of Biological Chemistry. Jun, 2013 | Pubmed ID: 23658016 PD123319 Augments Angiotensin II-induced Abdominal Aortic Aneurysms Through an AT2 Receptor-independent Mechanism PloS One. 2013 | Pubmed ID: 23593499 Differential Effects of Dietary Sodium Intake on Blood Pressure and Atherosclerosis in Hypercholesterolemic Mice The Journal of Nutritional Biochemistry. Jan, 2013 | Pubmed ID: 22705323 Depletion of Endothelial or Smooth Muscle Cell-specific Angiotensin II Type 1a Receptors Does Not Influence Aortic Aneurysms or Atherosclerosis in LDL Receptor Deficient Mice PloS One. 2012 | Pubmed ID: 23236507 Regional Variation in Aortic AT1b Receptor MRNA Abundance is Associated with Contractility but Unrelated to Atherosclerosis and Aortic Aneurysms PloS One. 2012 | Pubmed ID: 23119030 Doxycycline Does Not Influence Established Abdominal Aortic Aneurysms in Angiotensin II-infused Mice PloS One. 2012 | Pubmed ID: 23029514 Atherogenic and Pulmonary Responses of ApoE- and LDL Receptor-deficient Mice to Sidestream Cigarette Smoke Toxicology. Sep, 2012 | Pubmed ID: 22659316 Deficiency of Receptor-associated Protein Attenuates Angiotensin II-induced Atherosclerosis in Hypercholesterolemic Mice Without Influencing Abdominal Aortic Aneurysms Atherosclerosis. Feb, 2012 | Pubmed ID: 22153700 Calpain Inhibition Attenuates Angiotensin II-induced Abdominal Aortic Aneurysms and Atherosclerosis in Low-density Lipoprotein Receptor-deficient Mice Journal of Cardiovascular Pharmacology. Jan, 2012 | Pubmed ID: 21964156 Comparative Effects of Different Modes of Renin Angiotensin System Inhibition on Hypercholesterolaemia-induced Atherosclerosis British Journal of Pharmacology. Oct, 2011 | Pubmed ID: 22014125 MyD88 Deficiency Attenuates Angiotensin II-induced Abdominal Aortic Aneurysm Formation Independent of Signaling Through Toll-like Receptors 2 and 4 Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2011 | Pubmed ID: 21960563 Prolonged Infusion of Angiotensin II in ApoE(-/-) Mice Promotes Macrophage Recruitment with Continued Expansion of Abdominal Aortic Aneurysm The American Journal of Pathology. Sep, 2011 | Pubmed ID: 21763672 Endothelial Cell-specific Deficiency of Ang II Type 1a Receptors Attenuates Ang II-induced Ascending Aortic Aneurysms in LDL Receptor-/- Mice Circulation Research. Mar, 2011 | Pubmed ID: 21252156 Angiotensin-converting Enzyme 2 Deficiency in Whole Body or Bone Marrow-derived Cells Increases Atherosclerosis in Low-density Lipoprotein Receptor-/- Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2011 | Pubmed ID: 21252069 Telomerase Deficiency in Bone Marrow-derived Cells Attenuates Angiotensin II-induced Abdominal Aortic Aneurysm Formation Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2011 | Pubmed ID: 21088250 Group X Secretory Phospholipase A(2) Augments Angiotensin II-induced Inflammatory Responses and Abdominal Aortic Aneurysm Formation in ApoE-deficient Mice Atherosclerosis. Jan, 2011 | Pubmed ID: 20833395 Deficiency of the NR4A Orphan Nuclear Receptor NOR1 Decreases Monocyte Adhesion and Atherosclerosis Circulation Research. Aug, 2010 | Pubmed ID: 20558821 Dietary Coenzyme Q10 Does Not Protect Against Cigarette Smoke-augmented Atherosclerosis in ApoE-deficient Mice Free Radical Biology & Medicine. Jun, 2010 | Pubmed ID: 20227489 Angiotensin II Infusion Promotes Ascending Aortic Aneurysms: Attenuation by CCR2 Deficiency in ApoE-/- Mice Clinical Science (London, England : 1979). Jun, 2010 | Pubmed ID: 20088827 Modes of Defining Atherosclerosis in Mouse Models: Relative Merits and Evolving Standards Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19763919 ANG II Infusion Promotes Abdominal Aortic Aneurysms Independent of Increased Blood Pressure in Hypercholesterolemic Mice American Journal of Physiology. Heart and Circulatory Physiology. May, 2009 | Pubmed ID: 19252100 Interferon-gamma and the Interferon-inducible Chemokine CXCL10 Protect Against Aneurysm Formation and Rupture Circulation. Jan, 2009 | Pubmed ID: 19139386 Rapid Dilation of the Abdominal Aorta During Infusion of Angiotensin II Detected by Noninvasive High-frequency Ultrasonography Journal of Vascular Surgery : Official Publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter. Aug, 2006 | Pubmed ID: 16890871 Angiotensin II Infusion Induces Site-specific Intra-laminar Hemorrhage in Macrophage Colony-stimulating Factor-deficient Mice Atherosclerosis. Jun, 2006 | Pubmed ID: 16153649 Aldosterone Does Not Mediate Angiotensin II-induced Atherosclerosis and Abdominal Aortic Aneurysms British Journal of Pharmacology. Feb, 2005 | Pubmed ID: 15655500 Ozmotik kullanarak Subkutan Anjiotensin II İnfüzyon Farelerde İndükler Aort anevrizmaları Pompalar Hong Lu1, Deborah A. Howatt1, Anju Balakrishnan1, Jessica J. Moorleghen1, Debra L. Rateri1, Lisa A. Cassis2, Alan Daugherty1 1Saha Cardiovascular Research Center, University of Kentucky, 2Department of Pharmacology and Nutritional Sciences, University of Kentucky JoVE 53191 Medicine
Ozmotik kullanarak Subkutan Anjiotensin II İnfüzyon Farelerde İndükler Aort anevrizmaları Pompalar Hong Lu1, Deborah A. Howatt1, Anju Balakrishnan1, Jessica J. Moorleghen1, Debra L. Rateri1, Lisa A. Cassis2, Alan Daugherty1 1Saha Cardiovascular Research Center, University of Kentucky, 2Department of Pharmacology and Nutritional Sciences, University of Kentucky JoVE 53191 Medicine