Edwin Roger Parra

Publications

• Editorial: Multiplexed Image Analysis for Translational Research Project Applications
  Frontiers in Oncology. 2022  |   Pubmed ID: 36465347
• Immunogenomic Profiling of Lung Adenocarcinoma Reveals Poorly Differentiated Tumors Are Associated with an Immunogenic Tumor Microenvironment
  Lung Cancer (Amsterdam, Netherlands). Oct, 2022  |   Pubmed ID: 35973335
• Durvalumab Plus Tremelimumab in Advanced or Metastatic Soft Tissue and Bone Sarcomas: a Single-centre Phase 2 Trial
  The Lancet. Oncology. Sep, 2022  |   Pubmed ID: 35934010
• Multiplex Immunofluorescence and the Digital Image Analysis Workflow for Evaluation of the Tumor Immune Environment in Translational Research
  Frontiers in Oncology. 2022  |   Pubmed ID: 35832550
• Pathological Response and Immune Biomarker Assessment in Non-Small-Cell Lung Carcinoma Receiving Neoadjuvant Immune Checkpoint Inhibitors
  Cancers. Jun, 2022  |   Pubmed ID: 35681755
• Impact of Region-of-Interest Size on Immune Profiling Using Multiplex Immunofluorescence Tyramide Signal Amplification for Paraffin-Embedded Tumor Tissues
  Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. May, 2022  |   Pubmed ID: 35609532
• Effector Memory Cytotoxic CD3/CD8/CD45RO T Cells Are Predictive of Good Survival and a Lower Risk of Recurrence in Triple-negative Breast Cancer
  Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Nov, 2021  |   Pubmed ID: 34839351
• Cold and Heterogeneous T Cell Repertoire is Associated with Copy Number Aberrations and Loss of Immune Genes in Small-cell Lung Cancer
  Nature Communications. 11, 2021  |   Pubmed ID: 34789716
• Single Cell T Cell Landscape and T Cell Receptor Repertoire Profiling of AML in Context of PD-1 Blockade Therapy
  Nature Communications. 10, 2021  |   Pubmed ID: 34663807
• Best Practices for Technical Reproducibility Assessment of Multiplex Immunofluorescence
  Frontiers in Molecular Biosciences. 2021  |   Pubmed ID: 34532339
• Pathology Quality Control for Multiplex Immunofluorescence and Image Analysis Assessment in Longitudinal Studies
  Frontiers in Molecular Biosciences. 2021  |   Pubmed ID: 34395517
• A Proteogenomic Portrait of Lung Squamous Cell Carcinoma
  Cell. 08, 2021  |   Pubmed ID: 34358469
• Methods to Determine and Analyze the Cellular Spatial Distribution Extracted From Multiplex Immunofluorescence Data to Understand the Tumor Microenvironment
  Frontiers in Molecular Biosciences. 2021  |   Pubmed ID: 34179080
• Multiplex Immunofluorescence Tyramide Signal Amplification for Immune Cell Profiling of Paraffin-Embedded Tumor Tissues
  Frontiers in Molecular Biosciences. 2021  |   Pubmed ID: 33996912
• Author Correction: Multi-region Exome Sequencing Reveals Genomic Evolution from Preneoplasia to Lung Adenocarcinoma
  Nature Communications. May, 2021  |   Pubmed ID: 33980839
• Contextual Cues from Cancer Cells Govern Cancer-associated Fibroblast Heterogeneity
  Cell Reports. 04, 2021  |   Pubmed ID: 33882319
• Immuno-profiling and Cellular Spatial Analysis Using Five Immune Oncology Multiplex Immunofluorescence Panels for Paraffin Tumor Tissue
  Scientific Reports. 04, 2021  |   Pubmed ID: 33875760
• Pilot Clinical Trial of Perioperative Durvalumab and Tremelimumab in the Treatment of Resectable Colorectal Cancer Liver Metastases
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 06, 2021  |   Pubmed ID: 33811152
• Case Report: Enfortumab Vedotin for Metastatic Urothelial Carcinoma: A Case Series on the Clinical and Histopathologic Spectrum of Adverse Cutaneous Reactions From Fatal Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis to Dermal Hypersensitivity Reaction
  Frontiers in Oncology. 2021  |   Pubmed ID: 33747934
• Western Blot As a Support Technique for Immunohistochemistry to Detect Programmed Cell Death Ligand 1 Expression
  Methods in Molecular Biology (Clifton, N.J.). 2021  |   Pubmed ID: 33683685
• Detection of Programmed Cell Death Ligand 1 Expression in Lung Cancer Clinical Samples by an Automated Immunohistochemistry System
  Methods in Molecular Biology (Clifton, N.J.). 2021  |   Pubmed ID: 33683684
• Identification of Distinct Immune Landscapes Using an Automated Nine-color Multiplex Immunofluorescence Staining Panel and Image Analysis in Paraffin Tumor Tissues
  Scientific Reports. 02, 2021  |   Pubmed ID: 33633208
• Multi-omic Molecular Profiling Reveals Potentially Targetable Abnormalities Shared Across Multiple Histologies of Brain Metastasis
  Acta Neuropathologica. 02, 2021  |   Pubmed ID: 33394124
• Variants in Epithelial-Mesenchymal Transition and Immune Checkpoint Genes Are Associated With Immune Cell Profiles and Predict Survival in Non-Small Cell Lung Cancer
  Archives of Pathology & Laboratory Medicine. 10, 2020  |   Pubmed ID: 32150457
• Comprehensive T Cell Repertoire Characterization of Non-small Cell Lung Cancer
  Nature Communications. 01, 2020  |   Pubmed ID: 32001676
• Procedural Requirements and Recommendations for Multiplex Immunofluorescence Tyramide Signal Amplification Assays to Support Translational Oncology Studies
  Cancers. Jan, 2020  |   Pubmed ID: 31972974
• Multiplex Immunofluorescence Assays
  Methods in Molecular Biology (Clifton, N.J.). 2020  |   Pubmed ID: 31502166
• Multi-region Exome Sequencing Reveals Genomic Evolution from Preneoplasia to Lung Adenocarcinoma
  Nature Communications. 07, 2019  |   Pubmed ID: 31278276
• Targeting the Interplay Between Epithelial-to-Mesenchymal-Transition and the Immune System for Effective Immunotherapy
  Cancers. May, 2019  |   Pubmed ID: 31137625
• B7-H3 Expression in Merkel Cell Carcinoma-Associated Endothelial Cells Correlates with Locally Aggressive Primary Tumor Features and Increased Vascular Density
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 06, 2019  |   Pubmed ID: 30808776
• State-of-the-Art of Profiling Immune Contexture in the Era of Multiplexed Staining and Digital Analysis to Study Paraffin Tumor Tissues
  Cancers. Feb, 2019  |   Pubmed ID: 30791580
• Usefulness of Complementary Next-generation Sequencing and Quantitative Immunohistochemistry Panels for Predicting Brain Metastases and Selecting Treatment Outcomes of Non-small Cell Lung Cancer
  Human Pathology. 01, 2019  |   Pubmed ID: 30218756
• Histomorphometric Evaluation of the Ki-67 Proliferation Rate and CD34 Microvascular and D2-40 Lymphovascular Densities Drives the Pulmonary Typical Carcinoid Outcome
  Human Pathology. 11, 2018  |   Pubmed ID: 30031097
• A Functional Spatial Analysis Platform for Discovery of Immunological Interactions Predictive of Low-Grade to High-Grade Transition of Pancreatic Intraductal Papillary Mucinous Neoplasms
  Cancer Informatics. 2018  |   Pubmed ID: 30013304
• Effect of Neoadjuvant Chemotherapy on the Immune Microenvironment in Non-small Cell Lung Carcinomas As Determined by Multiplex Immunofluorescence and Image Analysis Approaches
  Journal for Immunotherapy of Cancer. Jun, 2018  |   Pubmed ID: 29871672
• Immunohistochemical and Image Analysis-Based Study Shows That Several Immune Checkpoints Are Co-expressed in Non-Small Cell Lung Carcinoma Tumors
  Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. 06, 2018  |   Pubmed ID: 29526824
• Validation of Multiplex Immunofluorescence Panels Using Multispectral Microscopy for Immune-profiling of Formalin-fixed and Paraffin-embedded Human Tumor Tissues
  Scientific Reports. Oct, 2017  |   Pubmed ID: 29042640
• 4-1BB Agonist Focuses CD8(+) Tumor-Infiltrating T-Cell Growth into a Distinct Repertoire Capable of Tumor Recognition in Pancreatic Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2017  |   Pubmed ID: 28947567