Erick O. Hernández-Ochoa Department of Biochemistry and Molecular Biology University of Maryland School of Medicine Biography Publications Institution JoVE Articles Erick O. Hernández-Ochoa has not added a biography. If you are Erick O. Hernández-Ochoa and would like to personalize this page please email our Author Liaison for assistance. Publications Voltage Sensor Current, SR Ca Release, and Ca Channel Current During Trains of Action Potential-like Depolarizations of Skeletal Muscle Fibers Physiological Reports. May, 2023 | Pubmed ID: 37147904 Contribution of Skeletal Muscle-specific MicroRNA-133b to Insulin Resistance in Heart Failure American Journal of Physiology. Heart and Circulatory Physiology. May, 2023 | Pubmed ID: 36827227 Advances in Ca1.1 Gating: New Insights into Permeation and Voltage-sensing Mechanisms Channels (Austin, Tex.). Dec, 2023 | Pubmed ID: 36642864 Selective Posttranslational Inhibition of Caβ-associated Voltage-dependent Calcium Channels with a Functionalized Nanobody Nature Communications. Dec, 2022 | Pubmed ID: 36494348 Voltage Sensor Movements of Ca1.1 During an Action Potential in Skeletal Muscle Fibers Proceedings of the National Academy of Sciences of the United States of America. Oct, 2021 | Pubmed ID: 34583989 CaMKII Oxidation is a Critical Performance/disease Trade-off Acquired at the Dawn of Vertebrate Evolution Nature Communications. May, 2021 | Pubmed ID: 34039988 Optical Recording of Action Potential Initiation and Propagation in Mouse Skeletal Muscle Fibers Biophysical Journal. Dec, 2018 | Pubmed ID: 30448039 LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Regulates Smooth Muscle Contractility by Modulating Ca Signaling and Expression of Cytoskeleton-Related Proteins Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2018 | Pubmed ID: 30354243 Loss of S100A1 Expression Leads to Ca Release Potentiation in Mutant Mice with Disrupted CaM and S100A1 Binding to CaMBD2 of RyR1 Physiological Reports. Aug, 2018 | Pubmed ID: 30101473 Voltage Sensing Mechanism in Skeletal Muscle Excitation-contraction Coupling: Coming of Age or Midlife Crisis? Skeletal Muscle. Jul, 2018 | Pubmed ID: 30025545 Real-time Scratch Assay Reveals Mechanisms of Early Calcium Signaling in Breast Cancer Cells in Response to Wounding Oncotarget. May, 2018 | Pubmed ID: 29861849 The Underlying Mechanisms of Diabetic Myopathy Journal of Diabetes Research. 2017 | Pubmed ID: 29238729 Acute Elevated Glucose Promotes Abnormal Action Potential-Induced Ca Transients in Cultured Skeletal Muscle Fibers Journal of Diabetes Research. 2017 | Pubmed ID: 28835899 The Activation of Protein Kinase A by the Calcium-Binding Protein S100A1 Is Independent of Cyclic AMP Biochemistry. May, 2017 | Pubmed ID: 28409622 Altered Nuclear Dynamics in MDX Myofibers Journal of Applied Physiology (Bethesda, Md. : 1985). Mar, 2017 | Pubmed ID: 27979987 Impaired Calcium Signaling in Muscle Fibers from Intercostal and Foot Skeletal Muscle in a Cigarette Smoke-induced Mouse Model of COPD Muscle & Nerve. Aug, 2017 | Pubmed ID: 27862020 In Vivo Assessment of Muscle Contractility in Animal Studies Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 27492180 Alternating Bipolar Field Stimulation Identifies Muscle Fibers with Defective Excitability but Maintained Local Ca(2+) Signals and Contraction Skeletal Muscle. 2016 | Pubmed ID: 26855765 Critical Role of Intracellular RyR1 Calcium Release Channels in Skeletal Muscle Function and Disease Frontiers in Physiology. 2015 | Pubmed ID: 26793121 Diabetic Myopathy and Mechanisms of Disease Biochemistry & Pharmacology : Open Access. Oct, 2015 | Pubmed ID: 26693099 Disruption of Action Potential and Calcium Signaling Properties in Malformed Myofibers from Dystrophin-deficient Mice Physiological Reports. Apr, 2015 | Pubmed ID: 25907787 β1a490-508, a 19-residue Peptide from C-terminal Tail of Cav1.1 β1a Subunit, Potentiates Voltage-dependent Calcium Release in Adult Skeletal Muscle Fibers Biophysical Journal. Feb, 2014 | Pubmed ID: 24507594 Atypical Behavior of NFATc1 in Cultured Intercostal Myofibers Skeletal Muscle. Jan, 2014 | Pubmed ID: 24383888 Elevated Nuclear Foxo1 Suppresses Excitability of Skeletal Muscle Fibers American Journal of Physiology. Cell Physiology. Sep, 2013 | Pubmed ID: 23804205 A Calcium Channel Mutant Mouse Model of Hypokalemic Periodic Paralysis The Journal of Clinical Investigation. Dec, 2012 | Pubmed ID: 23187123 NOX2-dependent ROS is Required for HDAC5 Nuclear Efflux and Contributes to HDAC4 Nuclear Efflux During Intense Repetitive Activity of Fast Skeletal Muscle Fibers American Journal of Physiology. Cell Physiology. Aug, 2012 | Pubmed ID: 22648949 Voltage Clamp Methods for the Study of Membrane Currents and SR Ca(2+) Release in Adult Skeletal Muscle Fibres Progress in Biophysics and Molecular Biology. Apr, 2012 | Pubmed ID: 22306655 Mice Null for Calsequestrin 1 Exhibit Deficits in Functional Performance and Sarcoplasmic Reticulum Calcium Handling PloS One. 2011 | Pubmed ID: 22164205 Adherent Primary Cultures of Mouse Intercostal Muscle Fibers for Isolated Fiber Studies Journal of Biomedicine & Biotechnology. 2011 | Pubmed ID: 21869860 S100A1 and Calmodulin Regulation of Ryanodine Receptor in Striated Muscle Cell Calcium. Oct, 2011 | Pubmed ID: 21784520 Effects of Conformational Peptide Probe DP4 on Bidirectional Signaling Between DHPR and RyR1 Calcium Channels in Voltage-clamped Skeletal Muscle Fibers Biophysical Journal. May, 2011 | Pubmed ID: 21575570 Modulation Des Sarkoplasmatischen Retikulum Ca2 + Release in Der Skelettmuskulatur Ausdrücken Ryanodin-Rezeptor, Die in Der Verordnung Durch Calmodulin Und S100A1 Beeinträchtigt American Journal of Physiology. Cell Physiology. May, 2011 | Pubmed ID: 21289290 DNA Binding Sites Target Nuclear NFATc1 to Heterochromatin Regions in Adult Skeletal Muscle Fibers Histochemistry and Cell Biology. Oct, 2010 | Pubmed ID: 20865272 Augmentation of Cav1 Channel Current and Action Potential Duration After Uptake of S100A1 in Sympathetic Ganglion Neurons American Journal of Physiology. Cell Physiology. Oct, 2009 | Pubmed ID: 19657060 The Qgamma Component of Intra-membrane Charge Movement is Present in Mammalian Muscle Fibres, but Suppressed in the Absence of S100A1 The Journal of Physiology. Sep, 2009 | Pubmed ID: 19651767 Simultaneous Recording of Intramembrane Charge Movement Components and Calcium Release in Wild-type and S100A1-/- Muscle Fibres The Journal of Physiology. Sep, 2009 | Pubmed ID: 19651766 S100A1 Binds to the Calmodulin-binding Site of Ryanodine Receptor and Modulates Skeletal Muscle Excitation-contraction Coupling The Journal of Biological Chemistry. Feb, 2008 | Pubmed ID: 18089560 Functional Site-Directed Fluorometry in Native Cells to Study Skeletal Muscle Excitability (Video) | JoVE Hugo Bibollet1, Daniel F. Bennett1, Martin F. Schneider1, Erick O. Hernández-Ochoa1 1Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine JoVE 65311 Biology
Functional Site-Directed Fluorometry in Native Cells to Study Skeletal Muscle Excitability (Video) | JoVE Hugo Bibollet1, Daniel F. Bennett1, Martin F. Schneider1, Erick O. Hernández-Ochoa1 1Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine JoVE 65311 Biology