Fred E. Regnier Department of Chemistry Purdue University Biography Publications Institution JoVE Articles Fred E. Regnier has not added a biography. If you are Fred E. Regnier and would like to personalize this page please email our Author Liaison for assistance. Publications A Lectin Chromatography/mass Spectrometry Discovery Workflow Identifies Putative Biomarkers of Aggressive Breast Cancers Journal of Proteome Research. Feb, 2012 | Pubmed ID: 22309216 Effect of Single Amino Acid Substitution on Oxidative Modifications of the Parkinson's Disease-Related Protein, DJ-1 Molecular & Cellular Proteomics : MCP. Feb, 2012 | Pubmed ID: 22104028 Determining the Effects of Antioxidants on Oxidative Stress Induced Carbonylation of Proteins Analytical Chemistry. Dec, 2011 | Pubmed ID: 21939227 Oxidative Stress Induced Carbonylation in Human Plasma Journal of Proteomics. Oct, 2011 | Pubmed ID: 21856457 Differential Carbonylation of Proteins As a Function of in Vivo Oxidative Stress Journal of Proteome Research. Sep, 2011 | Pubmed ID: 21800835 A Large, Consistent Plasma Proteomics Data Set from Prospectively Collected Breast Cancer Patient and Healthy Volunteer Samples Journal of Translational Medicine. 2011 | Pubmed ID: 21619653 A Lectin Affinity Workflow Targeting Glycosite-specific, Cancer-related Carbohydrate Structures in Trypsin-digested Human Plasma Analytical Biochemistry. Jan, 2011 | Pubmed ID: 20705048 Coupling Protein Complex Analysis to Peptide Based Proteomics Journal of Chromatography. A. Dec, 2010 | Pubmed ID: 21036361 Dynamics of Protein Damage in Yeast Frataxin Mutant Exposed to Oxidative Stress Omics : a Journal of Integrative Biology. Dec, 2010 | Pubmed ID: 20958246 Sialylated Lewis X Antigen Bearing Glycoproteins in Human Plasma Journal of Proteome Research. Nov, 2010 | Pubmed ID: 20858014 Proteomic Identification of Carbonylated Proteins and Their Oxidation Sites Journal of Proteome Research. Aug, 2010 | Pubmed ID: 20521848 Screening Antibody and Immunosorbent Selectivity by Two-dimensional Liquid Chromatography-MS/MS (2-D LC-MS/MS) Journal of Separation Science. Jun, 2010 | Pubmed ID: 20405482 Multi-dimensional Liquid Chromatography in Proteomics--a Review Analytica Chimica Acta. Apr, 2010 | Pubmed ID: 20363391 Profiling Carbonylated Proteins in Human Plasma Journal of Proteome Research. Mar, 2010 | Pubmed ID: 20121119 Analytical Validation of Protein-based Multiplex Assays: a Workshop Report by the NCI-FDA Interagency Oncology Task Force on Molecular Diagnostics Clinical Chemistry. Feb, 2010 | Pubmed ID: 20007859 Protein-based Multiplex Assays: Mock Presubmissions to the US Food and Drug Administration Clinical Chemistry. Feb, 2010 | Pubmed ID: 20007858 In Vitro Stable Isotope Labeling for Discovery of Novel Metabolites by Liquid Chromatography-mass Spectrometry: Confirmation of Gamma-tocopherol Metabolism in Human A549 Cell Journal of Chromatography. A. Jan, 2010 | Pubmed ID: 20006340 Sweetening the Pot: Adding Glycosylation to the Biomarker Discovery Equation Clinical Chemistry. Feb, 2010 | Pubmed ID: 19959616 Oxidative Stress Studies in Yeast with a Frataxin Mutant: a Proteomics Perspective Journal of Proteome Research. Feb, 2010 | Pubmed ID: 19957947 Repeatability and Reproducibility in Proteomic Identifications by Liquid Chromatography-tandem Mass Spectrometry Journal of Proteome Research. Feb, 2010 | Pubmed ID: 19921851 Interlaboratory Study Characterizing a Yeast Performance Standard for Benchmarking LC-MS Platform Performance Molecular & Cellular Proteomics : MCP. Feb, 2010 | Pubmed ID: 19858499 Performance Metrics for Liquid Chromatography-tandem Mass Spectrometry Systems in Proteomics Analyses Molecular & Cellular Proteomics : MCP. Feb, 2010 | Pubmed ID: 19837981 Multi-site Assessment of the Precision and Reproducibility of Multiple Reaction Monitoring-based Measurements of Proteins in Plasma Nature Biotechnology. Jul, 2009 | Pubmed ID: 19561596 Glycoproteomics of Plasma Based on Narrow Selectivity Lectin Affinity Chromatography Journal of Proteome Research. Feb, 2009 | Pubmed ID: 19099503 Comparative Metabolite Profiling of Carboxylic Acids in Rat Urine by CE-ESI MS/MS Through Positively Pre-charged and (2)H-coded Derivatization Electrophoresis. Nov, 2008 | Pubmed ID: 19035407 Simultaneous Quantification of Metabolites Involved in Central Carbon and Energy Metabolism Using Reversed-phase Liquid Chromatography-mass Spectrometry and in Vitro 13C Labeling Analytical Chemistry. Dec, 2008 | Pubmed ID: 19007244 Use of Glycan Targeting Antibodies to Identify Cancer-associated Glycoproteins in Plasma of Breast Cancer Patients Analytical Chemistry. Jul, 2008 | Pubmed ID: 18558770 Two-dimensional Correlation Optimized Warping Algorithm for Aligning GC X GC-MS Data Analytical Chemistry. Apr, 2008 | Pubmed ID: 18351753 Comprehensive Two-dimensional Gas Chromatography/time-of-flight Mass Spectrometry Peak Sorting Algorithm Journal of Chromatography. A. Feb, 2008 | Pubmed ID: 18093607 Differential Metabolomics Using Stable Isotope Labeling and Two-dimensional Gas Chromatography with Time-of-flight Mass Spectrometry Analytical Chemistry. Jan, 2008 | Pubmed ID: 18052339 Adaptive Interferometry of Protein on a BioCD Applied Optics. Aug, 2007 | Pubmed ID: 17676154 Enhancement of the LC/MS Analysis of Fatty Acids Through Derivatization and Stable Isotope Coding Analytical Chemistry. Jul, 2007 | Pubmed ID: 17492837 An Isotope Coding Strategy for Proteomics Involving Both Amine and Carboxyl Group Labeling Methods in Molecular Biology (Clifton, N.J.). 2007 | Pubmed ID: 17484114 Destabilization of DJ-1 by Familial Substitution and Oxidative Modifications: Implications for Parkinson's Disease Biochemistry. May, 2007 | Pubmed ID: 17451229 Neural Network Prediction of Peptide Separation in Strong Anion Exchange Chromatography Bioinformatics (Oxford, England). Jan, 2007 | Pubmed ID: 17092987 Targeted Glycoproteomics: Serial Lectin Affinity Chromatography in the Selection of O-glycosylation Sites on Proteins from the Human Blood Proteome Journal of Chromatography. A. Nov, 2006 | Pubmed ID: 16919642 Enhancement of Amino Acid Detection and Quantification by Electrospray Ionization Mass Spectrometry Analytical Chemistry. Jul, 2006 | Pubmed ID: 16808485 Primary Amine Coding As a Path to Comparative Proteomics Proteomics. Jul, 2006 | Pubmed ID: 16800033 Comparative Glycoproteomics of N-linked Complex-type Glycoforms Containing Sialic Acid in Human Serum Analytical Chemistry. Nov, 2005 | Pubmed ID: 16285669 Recent Advancements in Differential Proteomics Based on Stable Isotope Coding Briefings in Functional Genomics & Proteomics. Jul, 2005 | Pubmed ID: 16102271 An Automated Method for the Analysis of Stable Isotope Labeling Data in Proteomics Journal of the American Society for Mass Spectrometry. Jul, 2005 | Pubmed ID: 15922621 Use of Multidimensional Lectin Affinity Chromatography in Differential Glycoproteomics Analytical Chemistry. May, 2005 | Pubmed ID: 15859596 Processing of Data Generated by 2-dimensional Gel Electrophoresis for Statistical Analysis: Missing Data, Normalization, and Statistics Journal of Proteome Research. Nov-Dec, 2004 | Pubmed ID: 15595730 Optimization of Diagonal Chromatography for Recognizing Post-translational Modifications Journal of Chromatography. A. Aug, 2004 | Pubmed ID: 15460252 Benzoyl Derivatization As a Method to Improve Retention of Hydrophilic Peptides in Tryptic Peptide Mapping Analytical Chemistry. Oct, 2004 | Pubmed ID: 15456300 New Approach for Analysis of the Phosphotyrosine Proteome and Its Application to the Chicken B Cell Line, DT40 Journal of Proteome Research. Jul-Aug, 2004 | Pubmed ID: 15359727 Enrichment of Cysteine-containing Peptides from Tryptic Digests Using a Quaternary Amine Tag Analytical Chemistry. Aug, 2004 | Pubmed ID: 15283597 Proteomic Analysis of Carbonylated Proteins in Two-dimensional Gel Electrophoresis Using Avidin-fluorescein Affinity Staining Electrophoresis. May, 2004 | Pubmed ID: 15174056 High-speed Label-free Detection by Spinning-disk Micro-interferometry Biosensors & Bioelectronics. Jun, 2004 | Pubmed ID: 15093207 Proteomic Analysis of Arabidopsis Glutathione S-transferases from Benoxacor- and Copper-treated Seedlings The Journal of Biological Chemistry. Jun, 2004 | Pubmed ID: 15069083 Contributions of Commercial Sorbents to the Selectivity in Immobilized Metal Affinity Chromatography with Cu(II) Journal of Chromatography. A. Mar, 2004 | Pubmed ID: 15058570 Potential of Silica Monolithic Columns in Peptide Separations Journal of Chromatography. A. Mar, 2004 | Pubmed ID: 15043268 Effect of Microenvironment PH of Aluminum Hydroxide Adjuvant on the Chemical Stability of Adsorbed Antigen Vaccine. Mar, 2004 | Pubmed ID: 15003645 Histidine-rich Peptide Selection and Quantification in Targeted Proteomics Journal of Proteome Research. Jan-Feb, 2004 | Pubmed ID: 14998161 Regio-specific Adsorption of Cytochrome C on Negatively Charged Surfaces Analytical Chemistry. Apr, 2003 | Pubmed ID: 12713053 Stopped-flow Enzyme Assays on a Chip Using a Microfabricated Mixer Analytical Chemistry. Apr, 2003 | Pubmed ID: 12713034 Protein Proteolysis and the Multi-dimensional Electrochromatographic Separation of Histidine-containing Peptide Fragments on a Chip Journal of Chromatography. A. Jan, 2003 | Pubmed ID: 12564680 Capillary Electrochromatography of Peptides on Microfabricated Poly(dimethylsiloxane) Chips Modified by Cerium(IV)-catalyzed Polymerization Journal of Chromatography. A. Mar, 2002 | Pubmed ID: 12831199 An Isotope Coding Strategy for Proteomics Involving Both Amine and Carboxyl Group Labeling Journal of Proteome Research. Sep-Oct, 2002 | Pubmed ID: 12645916 Minimizing Resolution of Isotopically Coded Peptides in Comparative Proteomics Journal of Proteome Research. Mar-Apr, 2002 | Pubmed ID: 12643534 Controlling Deuterium Isotope Effects in Comparative Proteomics Analytical Chemistry. Aug, 2002 | Pubmed ID: 12175151 Global Internal Standard Technology for Comparative Proteomics Journal of Chromatography. A. Mar, 2002 | Pubmed ID: 11999733 Quantitative Proteomics Strategy Involving the Selection of Peptides Containing Both Cysteine and Histidine from Tryptic Digests of Cell Lysates Journal of Chromatography. A. Mar, 2002 | Pubmed ID: 11999731 Quantifying Peptides in Isotopically Labeled Protease Digests by Ion Mobility/time-of-flight Mass Spectrometry Analytical Chemistry. Mar, 2002 | Pubmed ID: 11924997 Comparative Proteomics Based on Stable Isotope Labeling and Affinity Selection Journal of Mass Spectrometry : JMS. Feb, 2002 | Pubmed ID: 11857757 שיטה לקטינים HPLC להעשיר פפטידים סלקטיבי-glycosylated מ דגימות ביולוגיות מורכבות Eric Johansen1, Birgit Schilling2, Michael Lerch1, Richard K. Niles1, Haichuan Liu1, Bensheng Li2, Simon Allen1, Steven C. Hall1, H. Ewa Witkowska1, Fred E. Regnier3, Bradford W. Gibson2, Susan J. Fisher1, Penelope M. Drake1 1Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco - UCSF, 2Buck Institute for Age Research, 3Department of Chemistry, Purdue University JoVE 1398 Biology
שיטה לקטינים HPLC להעשיר פפטידים סלקטיבי-glycosylated מ דגימות ביולוגיות מורכבות Eric Johansen1, Birgit Schilling2, Michael Lerch1, Richard K. Niles1, Haichuan Liu1, Bensheng Li2, Simon Allen1, Steven C. Hall1, H. Ewa Witkowska1, Fred E. Regnier3, Bradford W. Gibson2, Susan J. Fisher1, Penelope M. Drake1 1Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco - UCSF, 2Buck Institute for Age Research, 3Department of Chemistry, Purdue University JoVE 1398 Biology