Gabriella Lakos Medical Director INOVA Diagnostics, Inc. Biography Publications Institution JoVE Articles Gabriella Lakos has not added a biography. If you are Gabriella Lakos and would like to personalize this page please email our Author Liaison for assistance. Publications 14th International Congress on Antiphospholipid Antibodies Task Force. Report on Antiphospholipid Syndrome Laboratory Diagnostics and Trends Autoimmunity Reviews. May, 2014 | Pubmed ID: 24824074 Analytical and Clinical Comparison of Two Fully Automated Immunoassay Systems for the Diagnosis of Celiac Disease Journal of Immunology Research. 2014 | Pubmed ID: 24741592 Standardization of Antiphospholipid Antibody Testing--historical Perspectives and Ongoing Initiatives Seminars in Thrombosis and Hemostasis. Mar, 2014 | Pubmed ID: 24470286 Clinical Performance Evaluation of a Novel Rapid Response Chemiluminescent Immunoassay for the Detection of Autoantibodies to Extractable Nuclear Antigens Clinica Chimica Acta; International Journal of Clinical Chemistry. Sep, 2013 | Pubmed ID: 23727029 Superior Performance of the CCP3.1 Test Compared to CCP2 and MCV in the Rheumatoid Factor-negative RA Population Immunologic Research. Jul, 2013 | Pubmed ID: 23592053 Non-invasive Monitoring of Celiac Disease: Current Practice and Recent Advances MLO: Medical Laboratory Observer. Dec, 2012 | Pubmed ID: 23330518 Interference in Antiphospholipid Antibody Assays Seminars in Thrombosis and Hemostasis. Jun, 2012 | Pubmed ID: 22618529 Standards and Reference Materials for the Anticardiolipin and Anti-β2glycoprotein I Assays: a Report of Recommendations from the APL Task Force at the 13th International Congress on Antiphospholipid Antibodies Clinica Chimica Acta; International Journal of Clinical Chemistry. Jan, 2012 | Pubmed ID: 22019907 International Consensus Guidelines on Anticardiolipin and Anti-β2-glycoprotein I Testing: Report from the 13th International Congress on Antiphospholipid Antibodies Arthritis and Rheumatism. Jan, 2012 | Pubmed ID: 21953634 Anti-mutated Citrullinated Vimentin (anti-MCV) and Anti-65 KDa Heat Shock Protein (anti-hsp65): New Biomarkers in Ankylosing Spondylitis Joint, Bone, Spine : Revue Du Rhumatisme. Jan, 2012 | Pubmed ID: 21683641 Associations of HLA-shared Epitope, Anti-citrullinated Peptide Antibodies and Lifestyle-related Factors in Hungarian Patients with Rheumatoid Arthritis: Data from the First Central-Eastern European Cohort Joint, Bone, Spine : Revue Du Rhumatisme. Dec, 2011 | Pubmed ID: 21733730 Relationship Between Rheumatoid Factor Isotypes and IgG Anti-cyclic Citrullinated Peptide Antibodies The Journal of Rheumatology. Aug, 2010 | Pubmed ID: 20516016 Myth and Reality: Practical Test System for the Measurement of Anti-DNA Antibodies in the Diagnosis of Systemic Lupus Erythematosus (SLE) Journal of Clinical Laboratory Analysis. 2010 | Pubmed ID: 20333761 Myositis-specific and Myositis-associated Antibodies in Overlap Myositis in Comparison to Primary Dermatopolymyositis: Relevance for Clinical Classification: Retrospective Study of 169 Patients Joint, Bone, Spine : Revue Du Rhumatisme. Mar, 2010 | Pubmed ID: 20188618 Oxidized LDL Induces in Vitro Lymphocyte Activation in Antiphospholipid Syndrome Autoimmunity. Jun, 2010 | Pubmed ID: 20187701 New Classification of the Shared Epitope in Rheumatoid Arthritis: Impact on the Production of Various Anti-citrullinated Protein Antibodies Rheumatology (Oxford, England). Jan, 2010 | Pubmed ID: 19920092 Anti-citrullinated Protein/peptide Autoantibodies in Association with Genetic and Environmental Factors As Indicators of Disease Outcome in Rheumatoid Arthritis Autoimmunity Reviews. Jan, 2010 | Pubmed ID: 19427413 Anti-nuscleosome Antibody, a Reliable Indicator for Lupus Nephritis Autoimmunity. Aug, 2009 | Pubmed ID: 19811255 Identification of Rare Anti-phospholipid/protein Co-factor Autoantibodies in Patients with Systemic Lupus Erythematosus Autoimmunity. Sep, 2009 | Pubmed ID: 19626489 Immunological and Clinical Effects of Alphacalcidol in Patients with Psoriatic Arthropathy: Results of an Open, Follow-up Pilot Study Acta Dermato-venereologica. 2009 | Pubmed ID: 19325997 Evaluation of the Combined Application of Ethanol-fixed and Formaldehyde-fixed Neutrophil Substrates for Identifying Atypical Perinuclear Antineutrophil Cytoplasmic Antibodies in Inflammatory Bowel Disease Clinical and Vaccine Immunology : CVI. Apr, 2009 | Pubmed ID: 19193830 Combined Plasmapheresis and High-dose Intravenous Immunoglobulin Treatment in Systemic Sclerosis for 12 Months: Follow-up of Immunopathological and Clinical Effects Clinical Rheumatology. Mar, 2009 | Pubmed ID: 19067103 Rheumatoid Arthritis Diagnosis with Antimutated Citrullinated Vimentin ELISA by Orgentec Diagnostika Expert Opinion on Medical Diagnostics. Sep, 2008 | Pubmed ID: 23495927 Intracytoplasmic Cytokine Expression and T Cell Subset Distribution in the Peripheral Blood of Patients with Ankylosing Spondylitis The Journal of Rheumatology. Dec, 2008 | Pubmed ID: 19004035 Smad-independent Transforming Growth Factor-beta Regulation of Early Growth Response-1 and Sustained Expression in Fibrosis: Implications for Scleroderma The American Journal of Pathology. Oct, 2008 | Pubmed ID: 18772333 Associations Between Serum Anti-CCP Antibody, Rheumatoid Factor Levels and HLA-DR4 Expression in Hungarian Patients with Rheumatoid Arthritis The Israel Medical Association Journal : IMAJ. Jan, 2008 | Pubmed ID: 18300568 Anti-citrullinated Protein Antibodies in Rheumatoid Arthritis: As Good As It Gets? Clinical Reviews in Allergy & Immunology. Feb, 2008 | Pubmed ID: 18270854 Endothelial Dysfunction and Atherosclerosis in Rheumatoid Arthritis: a Multiparametric Analysis Using Imaging Techniques and Laboratory Markers of Inflammation and Autoimmunity The Journal of Rheumatology. Mar, 2008 | Pubmed ID: 18203326 Association of HELLP Syndrome with Primary Antiphospholipid Syndrome--a Case Report Clinical Rheumatology. Jan, 2008 | Pubmed ID: 17684701 Molecular Genetic Analysis of Hungarian Patients with the Hyper-immunoglobulin M Syndrome Molecular Immunology. Jan, 2008 | Pubmed ID: 17553565 Clinical Thrombotic Manifestations in SLE Patients with and Without Antiphospholipid Antibodies: a 5-year Follow-up Clinical Reviews in Allergy & Immunology. Apr, 2007 | Pubmed ID: 17916982 Increased Production of the Soluble Tumor-associated Antigens CA19-9, CA125, and CA15-3 in Rheumatoid Arthritis: Potential Adhesion Molecules in Synovial Inflammation? Annals of the New York Academy of Sciences. Jun, 2007 | Pubmed ID: 17893999 Disturbances in B- and T-cell Homeostasis in Rheumatoid Arthritis: Suggested Relationships with Antigen-driven Immune Responses Journal of Autoimmunity. Sep-Nov, 2007 | Pubmed ID: 17826949 Clinical Evaluation of Anti-mutated Citrullinated Vimentin by ELISA in Rheumatoid Arthritis The Journal of Rheumatology. Aug, 2007 | Pubmed ID: 17611988 Seroreactivity to Microbial Components in Crohn's Disease is Associated with Ileal Involvement, Noninflammatory Disease Behavior and NOD2/CARD15 Genotype, but Not with Risk for Surgery in a Hungarian Cohort of IBD Patients Inflammatory Bowel Diseases. Aug, 2007 | Pubmed ID: 17417801 Increased Bleomycin-induced Skin Fibrosis in Mice Lacking the Th1-specific Transcription Factor T-bet Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 2006 | Pubmed ID: 17314493 Intracellular TGF-beta Receptor Blockade Abrogates Smad-dependent Fibroblast Activation in Vitro and in Vivo The Journal of Investigative Dermatology. Aug, 2006 | Pubmed ID: 16741519 [Stiff-person Syndrome--two Hungarian Cases and Review of the Literature] Ideggyógyászati Szemle. Jul, 2005 | Pubmed ID: 16173274 [Is the Primary Antiphospholipid Syndrome a Forerunner of SLE?] Orvosi Hetilap. Jan, 2005 | Pubmed ID: 15773587 Is the Treatment of Hodgkin's Disease Detrimental to the Parathyroid Gland? Acta Haematologica. 2004 | Pubmed ID: 15345897 Animal Models of Scleroderma Methods in Molecular Medicine. 2004 | Pubmed ID: 15286396 Features Associated with Epilepsy in the Antiphospholipid Syndrome The Journal of Rheumatology. Jul, 2004 | Pubmed ID: 15229954 Targeted Disruption of TGF-beta/Smad3 Signaling Modulates Skin Fibrosis in a Mouse Model of Scleroderma The American Journal of Pathology. Jul, 2004 | Pubmed ID: 15215176 Disruption of Transforming Growth Factor Beta Signaling and Profibrotic Responses in Normal Skin Fibroblasts by Peroxisome Proliferator-activated Receptor Gamma Arthritis and Rheumatism. Apr, 2004 | Pubmed ID: 15077315 Relationship Between Skin Bacterial Colonization and the Occurrence of Allergen-specific and Non-allergen-specific Antibodies in Sera of Children with Atopic Eczema/dermatitis Syndrome Acta Dermato-venereologica. 2004 | Pubmed ID: 15040475 Coeliac Disease in Sjögren's Syndrome--a Study of 111 Hungarian Patients Rheumatology International. Sep, 2004 | Pubmed ID: 13680146 [Combined Therapy in Pregnancy with Primary Antiphospholipid Syndrome] Orvosi Hetilap. Dec, 2003 | Pubmed ID: 14725207 [Primary Antiphospholipid Syndrome Associated with HELLP Syndrome in Pregnancy] Orvosi Hetilap. Jul, 2003 | Pubmed ID: 12908149 [Successful High-dose Low-molecular-weight Heparin Thromboprophylaxis in Pregnant Women with Antiphospholipid Syndrome] Orvosi Hetilap. Jun, 2003 | Pubmed ID: 12858645 Sustained Activation of Fibroblast Transforming Growth Factor-beta/Smad Signaling in a Murine Model of Scleroderma The Journal of Investigative Dermatology. Jul, 2003 | Pubmed ID: 12839562 Transglutaminase 2-/- Mice Reveal a Phagocytosis-associated Crosstalk Between Macrophages and Apoptotic Cells Proceedings of the National Academy of Sciences of the United States of America. Jun, 2003 | Pubmed ID: 12810961 [Antiphospholipid Antibodies in Acute Coronary Syndrome] Orvosi Hetilap. Mar, 2003 | Pubmed ID: 12687795 Antiphospholipid Antibodies in Young Women with and Without Oral Contraceptive Use Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis. Jan, 2003 | Pubmed ID: 12544729 [Evaluation of Survival in Mixed Connective Tissue Disease (MCTD)] Orvosi Hetilap. Nov, 2002 | Pubmed ID: 12501560 No Effect of Transfusion Transmitted Virus Viremia on the Distribution and Activation of Peripheral Lymphocytes in Hemodialyzed Patients Nephron. Dec, 2002 | Pubmed ID: 12399644 [Jejunal Feeding in Necrotizing Pancreatitis or After Esophagectomy] Magyar Sebészet. Aug, 2002 | Pubmed ID: 12236086 [Does the TT Virus Affect T-cell Subgroups in Patients Undergoing Hemodialysis?] Orvosi Hetilap. Apr, 2002 | Pubmed ID: 12053884 Antiphospholipid Syndrome: Clinical and Immunologic Manifestations and Patterns of Disease Expression in a Cohort of 1,000 Patients Arthritis and Rheumatism. Apr, 2002 | Pubmed ID: 11953980 Plasmapheresis Modulates Th1/Th2 Imbalance in Patients with Systemic Lupus Erythematosus According to Measurement of Intracytoplasmic Cytokines Autoimmunity. Feb, 2002 | Pubmed ID: 11908707 Heat Shock Protein 70 is a Potent Activator of the Human Complement System Cell Stress & Chaperones. Jan, 2002 | Pubmed ID: 11892984 Anti-Nuclear Antibody Triagem Usando Células HEp-2 Carol Buchner1, Cassandra Bryant2, Anna Eslami3, Gabriella Lakos4 1IFA Development Manager, INOVA Diagnostics, Inc., 2IFA Development, INOVA Diagnostics, Inc., 3Product Manager, Rheumatology, INOVA Diagnostics, Inc., 4Medical Director, INOVA Diagnostics, Inc. JoVE 51211 Biology
Anti-Nuclear Antibody Triagem Usando Células HEp-2 Carol Buchner1, Cassandra Bryant2, Anna Eslami3, Gabriella Lakos4 1IFA Development Manager, INOVA Diagnostics, Inc., 2IFA Development, INOVA Diagnostics, Inc., 3Product Manager, Rheumatology, INOVA Diagnostics, Inc., 4Medical Director, INOVA Diagnostics, Inc. JoVE 51211 Biology