Gauri Rao UNC Eshelman School of Pharmacy University of North Carolina at Chapel Hill Biography Publications Institution JoVE Articles Gauri Rao has not added a biography. If you are Gauri Rao and would like to personalize this page please email our Author Liaison for assistance. Publications Clinical Challenges Treating Infections: an Update JAC-antimicrobial Resistance. Jun, 2022 | Pubmed ID: 35529051 Knowledge Dissemination and Central Indexing of Resources in Pharmacometrics: an ISOP Education Working Group Initiative Journal of Pharmacokinetics and Pharmacodynamics. Aug, 2022 | Pubmed ID: 35474412 Pharmacodynamic and Immunomodulatory Effects of Polymyxin B in Combination with Fosfomycin Against KPC-2-producing Klebsiella Pneumoniae International Journal of Antimicrobial Agents. Apr, 2022 | Pubmed ID: 35288260 Assessing the Predictive Performance of Population Pharmacokinetic Models for Intravenous Polymyxin B in Critically Ill Patients CPT: Pharmacometrics & Systems Pharmacology. 12, 2021 | Pubmed ID: 34811968 Insights Into Patient Variability During Ivacaftor-Lumacaftor Therapy in Cystic Fibrosis Frontiers in Pharmacology. 2021 | Pubmed ID: 34408649 Antibiotic Pharmacokinetic/pharmacodynamic Modelling: MIC, Pharmacodynamic Indices and Beyond International Journal of Antimicrobial Agents. Aug, 2021 | Pubmed ID: 34058336 Polymyxins for the Treatment of Lower Respiratory Tract Infections: Lessons Learned from the Integration of Clinical Pharmacokinetic Studies and Clinical Outcomes International Journal of Antimicrobial Agents. Jun, 2021 | Pubmed ID: 33785362 The Complex Roadmap to Infectious Disease Innovation: The Intersection of Bugs, Drugs, and Special Populations Clinical Pharmacology and Therapeutics. 04, 2021 | Pubmed ID: 33769563 Reapproaching Old Treatments: Considerations for PK/PD Studies on Phage Therapy for Bacterial Respiratory Infections Clinical Pharmacology and Therapeutics. 06, 2021 | Pubmed ID: 33615463 A Mechanism-based Pharmacokinetic Model of Remdesivir Leveraging Interspecies Scaling to Simulate COVID-19 Treatment in Humans CPT: Pharmacometrics & Systems Pharmacology. 02, 2021 | Pubmed ID: 33296558 Development of a Minimal Physiologically-Based Pharmacokinetic Model to Simulate Lung Exposure in Humans Following Oral Administration of Ivermectin for COVID-19 Drug Repurposing Journal of Pharmaceutical Sciences. 12, 2020 | Pubmed ID: 32891630 Impact of Antibiotic Resistance on Treatment of Pneumococcal Disease in Ethiopia: An Agent-Based Modeling Simulation The American Journal of Tropical Medicine and Hygiene. 11, 2019 | Pubmed ID: 31516111 Comparison of the Composition and in Vitro Activity of Polymyxin B Products International Journal of Antimicrobial Agents. Sep, 2018 | Pubmed ID: 29807163 Personalizing Polymyxin B Dosing Using an Adaptive Feedback Control Algorithm Antimicrobial Agents and Chemotherapy. 07, 2018 | Pubmed ID: 29760144 Validation of a Model Predicting Anti-infective Lung Penetration in the Epithelial Lining Fluid of Humans Pharmaceutical Research. Jan, 2018 | Pubmed ID: 29368211 Assessment and Modelling of Antibacterial Combination Regimens Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. Jul, 2018 | Pubmed ID: 29269090 Evaluation of Activity and Emergence of Resistance of Polymyxin B and ZTI-01 (Fosfomycin for Injection) Against KPC-Producing Klebsiella Pneumoniae Antimicrobial Agents and Chemotherapy. 02, 2018 | Pubmed ID: 29203494 Effect of Polymyxin B-containing Regimens on Renal Function for the Treatment of Carbapenem-resistant Enterobacteriacea Mediastinitis The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases. Jan - Feb, 2018 | Pubmed ID: 29182906 Triple Combination Antibiotic Therapy for Carbapenemase-producing Klebsiella Pneumoniae: a Systematic Review Annals of Clinical Microbiology and Antimicrobials. Nov, 2017 | Pubmed ID: 29178957 Assessment of Combined Polymyxin B and Minocycline Therapy Against Klebsiella Pneumoniae Carbapenemase (KPC)-Producing K. Pneumoniae Antimicrobial Agents and Chemotherapy. 07, 2017 | Pubmed ID: 28438930 Critical Need for Clarity in Polymyxin B Dosing Antimicrobial Agents and Chemotherapy. 05, 2017 | Pubmed ID: 28438796 Multi-scale Model of Drug Induced Adaptive Resistance of Gram-negative Bacteria to Polymyxin B PloS One. 2017 | Pubmed ID: 28334005 Polymyxin B in Combination with Rifampin and Meropenem Against Polymyxin B-Resistant KPC-Producing Klebsiella Pneumoniae Antimicrobial Agents and Chemotherapy. 02, 2017 | Pubmed ID: 27872078 Polymyxin B in Combination with Doripenem Against Heteroresistant Acinetobacter Baumannii: Pharmacodynamics of New Dosing Strategies The Journal of Antimicrobial Chemotherapy. 11, 2016 | Pubmed ID: 27494922 Combinatorial Pharmacodynamics of Polymyxin B and Tigecycline Against Heteroresistant Acinetobacter Baumannii International Journal of Antimicrobial Agents. Sep, 2016 | Pubmed ID: 27449542 Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection Rajnikant Sharma1, Shekhar Yeshwante1, Quentin Vallé1, Maytham Hussein2, Varsha Thombare2, Sean Michael McCann1, Robert Maile3,4,5, Jian Li6, Tony Velkov2, Gauri Rao1 1UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, 2Department of Biochemistry & Pharmacology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, 3Department of Microbiology & Immunology, University of North Carolina School of Medicine, 4Department of Surgery, University of North Carolina at Chapel Hill, 5Curriculum in Toxicology and Environmental Medicine, University of North Carolina at Chapel Hill, 6Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University JoVE 64345 Immunology and Infection Intraventricular Drug Delivery and Sampling for Pharmacokinetics and Pharmacodynamics Study Sara Oberrauch1, Jing Lu1, Linda Cornthwaite-Duncan1, Maytham Hussein1, Jian Li2, Gauri Rao3, Tony Velkov1 1Department of Biochemistry & Pharmacology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, 2Department of Microbiology, Biomedicine Discovery Institute, Monash University, 3UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill JoVE 63540 Neuroscience
Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection Rajnikant Sharma1, Shekhar Yeshwante1, Quentin Vallé1, Maytham Hussein2, Varsha Thombare2, Sean Michael McCann1, Robert Maile3,4,5, Jian Li6, Tony Velkov2, Gauri Rao1 1UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, 2Department of Biochemistry & Pharmacology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, 3Department of Microbiology & Immunology, University of North Carolina School of Medicine, 4Department of Surgery, University of North Carolina at Chapel Hill, 5Curriculum in Toxicology and Environmental Medicine, University of North Carolina at Chapel Hill, 6Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University JoVE 64345 Immunology and Infection
Intraventricular Drug Delivery and Sampling for Pharmacokinetics and Pharmacodynamics Study Sara Oberrauch1, Jing Lu1, Linda Cornthwaite-Duncan1, Maytham Hussein1, Jian Li2, Gauri Rao3, Tony Velkov1 1Department of Biochemistry & Pharmacology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, 2Department of Microbiology, Biomedicine Discovery Institute, Monash University, 3UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill JoVE 63540 Neuroscience