Gianluigi Condorelli Humanitas Clinical and Research Center, Italy Biography Publications Institution JoVE Articles Gianluigi Condorelli has not added a biography. If you are Gianluigi Condorelli and would like to personalize this page please email our Author Liaison for assistance. Publications Epigenetics: a New Mechanism of Regulation of Heart Failure? Basic Research in Cardiology. Jul, 2013 | Pubmed ID: 23740219 HEXIM1: a New Player in Myocardial Hypertrophy? Cardiovascular Research. Jul, 2013 | Pubmed ID: 23720275 Circulating MicroRNAs and Aerobic Fitness--the HUNT-Study PloS One. 2013 | Pubmed ID: 23469005 Doubly Heterozygous LMNA and TTN Mutations Revealed by Exome Sequencing in a Severe Form of Dilated Cardiomyopathy European Journal of Human Genetics : EJHG. Mar, 2013 | Pubmed ID: 23463027 Platelets, Endothelium, and Circulating MicroRNA-126 As a Prognostic Biomarker in Cardiovascular Diseases: Per Aspirin Ad Astra European Heart Journal. Feb, 2013 | Pubmed ID: 23391580 Assessment of the 9p21.3 Locus in Severity of Coronary Artery Disease in the Presence and Absence of Type 2 Diabetes BMC Medical Genetics. 2013 | Pubmed ID: 23343465 Translating Cardioprotection for Patient Benefit: Position Paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology Cardiovascular Research. Apr, 2013 | Pubmed ID: 23334258 Induced Pluripotent Stem Cell-derived Cardiomyocytes in Studies of Inherited Arrhythmias The Journal of Clinical Investigation. Jan, 2013 | Pubmed ID: 23281414 The Circulating Level of FABP3 is an Indirect Biomarker of MicroRNA-1 Journal of the American College of Cardiology. Jan, 2013 | Pubmed ID: 23141496 CaMK4 Gene Deletion Induces Hypertension Journal of the American Heart Association. Aug, 2012 | Pubmed ID: 23130158 SOCS1 Gene Transfer Accelerates the Transition to Heart Failure Through the Inhibition of the Gp130/JAK/STAT Pathway Cardiovascular Research. Dec, 2012 | Pubmed ID: 22875468 [Continuity of Care in Heart Failure: Pilot Study of the Tuscany Region] Giornale Italiano Di Cardiologia (2006). Sep, 2012 | Pubmed ID: 22825347 The Might of MicroRNA in Mitochondria Circulation Research. Jun, 2012 | Pubmed ID: 22679134 Rheb is a Critical Regulator of Autophagy During Myocardial Ischemia: Pathophysiological Implications in Obesity and Metabolic Syndrome Circulation. Mar, 2012 | Pubmed ID: 22294621 Endothelial-to-mesenchymal Transition and MicroRNA-21: the Game is on Again Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2012 | Pubmed ID: 22258897 MiR-133a Regulates Collagen 1A1: Potential Role of MiR-133a in Myocardial Fibrosis in Angiotensin II-dependent Hypertension Journal of Cellular Physiology. Feb, 2012 | Pubmed ID: 21769867 Stem Cell Therapy in Heart Diseases: a Review of Selected New Perspectives, Practical Considerations and Clinical Applications Current Cardiology Reviews. Aug, 2011 | Pubmed ID: 22758618 MicroRNA-134 As a Potential Plasma Biomarker for the Diagnosis of Acute Pulmonary Embolism Journal of Translational Medicine. 2011 | Pubmed ID: 21943159 Arterial Remodeling and Atherosclerosis: MiRNAs Involvement Vascular Pharmacology. Oct, 2011 | Pubmed ID: 21864716 MicroRNA-133 Controls Vascular Smooth Muscle Cell Phenotypic Switch in Vitro and Vascular Remodeling in Vivo Circulation Research. Sep, 2011 | Pubmed ID: 21852550 ATP6V0A1 Polymorphism and MicroRNA-637: A Pathogenetic Role for MicroRNAs in Essential Hypertension at Last? Circulation. Cardiovascular Genetics. Aug, 2011 | Pubmed ID: 21846868 Association Study on Long-living Individuals from Southern Italy Identifies Rs10491334 in the CAMKIV Gene That Regulates Survival Proteins Rejuvenation Research. Jun, 2011 | Pubmed ID: 21612516 [Cardiac Stem Cell Therapy for the Treatment of Chronic Stable Angina Refractory to Conventional Therapy. State of the Art and Current Clinical Experience of the San Raffaele Hospital of Milan, Italy] Giornale Italiano Di Cardiologia (2006). Mar, 2011 | Pubmed ID: 21560476 IkappaB Kinase Epsilon and TANK-binding Kinase 1 Activate AKT by Direct Phosphorylation Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21464307 MicroRNAs in Hypertrophy and Heart Failure Experimental Biology and Medicine (Maywood, N.J.). Feb, 2011 | Pubmed ID: 21321308 Unexpectedly Low Mutation Rates in Beta-myosin Heavy Chain and Cardiac Myosin Binding Protein Genes in Italian Patients with Hypertrophic Cardiomyopathy Journal of Cellular Physiology. Nov, 2011 | Pubmed ID: 21302287 Deregulation of MicroRNA-503 Contributes to Diabetes Mellitus-induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia Circulation. Jan, 2011 | Pubmed ID: 21220732 Cardiovascular Side Effects of Cancer Therapies: a Position Statement from the Heart Failure Association of the European Society of Cardiology European Journal of Heart Failure. Jan, 2011 | Pubmed ID: 21169385 MicroRNA-199b Targets the Nuclear Kinase Dyrk1a in an Auto-amplification Loop Promoting Calcineurin/NFAT Signalling Nature Cell Biology. Dec, 2010 | Pubmed ID: 21102440 Circulating MicroRNAs As Potential Biomarkers of Coronary Artery Disease: a Promise to Be Fulfilled? Circulation Research. Sep, 2010 | Pubmed ID: 20814026 Reliable Resequencing of the Human Dystrophin Locus by Universal Long Polymerase Chain Reaction and Massive Pyrosequencing Analytical Biochemistry. Nov, 2010 | Pubmed ID: 20670611 MTORC1 Regulates Cardiac Function and Myocyte Survival Through 4E-BP1 Inhibition in Mice The Journal of Clinical Investigation. Aug, 2010 | Pubmed ID: 20644257 Immersion Before Dry Simulated Dive Reduces Cardiomyocyte Function and Increases Mortality After Decompression Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2010 | Pubmed ID: 20634356 MicroRNA Control of Podosome Formation in Vascular Smooth Muscle Cells in Vivo and in Vitro The Journal of Cell Biology. Apr, 2010 | Pubmed ID: 20351064 Epigenetics in Heart Failure Annals of the New York Academy of Sciences. Feb, 2010 | Pubmed ID: 20201899 Fatty Acid Percentage in Erythrocyte Membranes of Atrial Flutter/fibrillation Patients and Controls Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing. Mar, 2010 | Pubmed ID: 20162444 MicroRNAs in Heart Disease: Putative Novel Therapeutic Targets? European Heart Journal. Mar, 2010 | Pubmed ID: 20118173 Correlations Between Progression of Coronary Artery Disease and Circulating Endothelial Progenitor Cells FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2010 | Pubmed ID: 20056714 MicroRNA-133a Protects Against Myocardial Fibrosis and Modulates Electrical Repolarization Without Affecting Hypertrophy in Pressure-overloaded Adult Hearts Circulation Research. Jan, 2010 | Pubmed ID: 19893015 MicroRNAs in Cardiovascular Biology and Heart Disease Circulation. Cardiovascular Genetics. Aug, 2009 | Pubmed ID: 20031613 Reciprocal Regulation of MicroRNA-1 and Insulin-like Growth Factor-1 Signal Transduction Cascade in Cardiac and Skeletal Muscle in Physiological and Pathological Conditions Circulation. Dec, 2009 | Pubmed ID: 19933931 Akt Increases Sarcoplasmic Reticulum Ca2+ Cycling by Direct Phosphorylation of Phospholamban at Thr17 The Journal of Biological Chemistry. Oct, 2009 | Pubmed ID: 19696029 Interval Training Normalizes Cardiomyocyte Function, Diastolic Ca2+ Control, and SR Ca2+ Release Synchronicity in a Mouse Model of Diabetic Cardiomyopathy Circulation Research. Sep, 2009 | Pubmed ID: 19679837 MicroRNAs and Cardiac Pathology Nature Reviews. Cardiology. Jun, 2009 | Pubmed ID: 19434076 Cardiotoxic Effects, or Lack Thereof, of Anti-ErbB2 Immunoagents FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2009 | Pubmed ID: 19417081 Association of the FOXO3A Locus with Extreme Longevity in a Southern Italian Centenarian Study Rejuvenation Research. Apr, 2009 | Pubmed ID: 19415983 Akt Regulates L-type Ca2+ Channel Activity by Modulating Cavalpha1 Protein Stability The Journal of Cell Biology. Mar, 2009 | Pubmed ID: 19307602 RNA Silencing: Small RNA-mediated Posttranscriptional Regulation of MRNA and the Implications for Heart Electropathophysiology Journal of Cardiovascular Electrophysiology. Feb, 2009 | Pubmed ID: 19017333 Role of MicroRNAs in Haemopoiesis, Heart Hypertrophy and Cancer Biochemical Society Transactions. Dec, 2008 | Pubmed ID: 19021526 Inhibition of Class I Histone Deacetylase with an Apicidin Derivative Prevents Cardiac Hypertrophy and Failure Cardiovascular Research. Dec, 2008 | Pubmed ID: 18697792 On the Road to the Definition of the Cardiac MiRNome in Human Disease States Journal of Molecular and Cellular Cardiology. Aug, 2008 | Pubmed ID: 18619609 MicroRNAs: Components of an Integrated System Controlling Cardiac Development, Physiology, and Disease Pathogenesis Cardiovascular Research. Sep, 2008 | Pubmed ID: 18614548 MicroRNA and Cardiac Pathologies Physiological Genomics. Aug, 2008 | Pubmed ID: 18544659 Heart Failure: Targeting Transcriptional and Post-transcriptional Control Mechanisms of Hypertrophy for Treatment The International Journal of Biochemistry & Cell Biology. 2008 | Pubmed ID: 18514564 Carbon Monoxide Levels Experienced by Heavy Smokers Impair Aerobic Capacity and Cardiac Contractility and Induce Pathological Hypertrophy Inhalation Toxicology. May, 2008 | Pubmed ID: 18464052 Myocardial Sarcoplasmic Reticulum Ca2+ ATPase Function is Increased by Aerobic Interval Training European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology. Apr, 2008 | Pubmed ID: 18391639 MicroRNAs Control Gene Expression: Importance for Cardiac Development and Pathophysiology Annals of the New York Academy of Sciences. Mar, 2008 | Pubmed ID: 18375574 State-of-the-Art Prevention of Heart Failure: Maladaptive Versus Adaptive Hypertrophy Heart Failure Monitor. 2008 | Pubmed ID: 18273494 Physiological Myocardial Hypertrophy: How and Why? Frontiers in Bioscience : a Journal and Virtual Library. 2008 | Pubmed ID: 17981549 Activation or Inactivation of Cardiac Akt/mTOR Signaling Diverges Physiological from Pathological Hypertrophy Journal of Cellular Physiology. Feb, 2008 | Pubmed ID: 17941081 Emerging Role of MicroRNAs in Cardiovascular Biology Circulation Research. Dec, 2007 | Pubmed ID: 18063818 Human Stem Cells for Heart Failure Treatment Ready for Prime Time? Journal of the American College of Cardiology. Nov, 2007 | Pubmed ID: 17980257 Aerobic Interval Training Enhances Cardiomyocyte Contractility and Ca2+ Cycling by Phosphorylation of CaMKII and Thr-17 of Phospholamban Journal of Molecular and Cellular Cardiology. Sep, 2007 | Pubmed ID: 17689560 MicroRNA-133 Controls Cardiac Hypertrophy Nature Medicine. May, 2007 | Pubmed ID: 17468766 Human Embryonic Stem Cell-derived Cardiomyocytes: Inducing Strategies Regenerative Medicine. Mar, 2006 | Pubmed ID: 17465802 Effects of Akt on Cardiac Myocytes: Location Counts Circulation Research. Aug, 2006 | Pubmed ID: 16917099 Sources of Cardiomyocytes for Stem Cell Therapy: an Update Pediatric Research. Apr, 2006 | Pubmed ID: 16549553 Direct Intramyocardial Percutaneous Delivery of Autologous Bone Marrow in Patients with Refractory Myocardial Angina American Heart Journal. Mar, 2006 | Pubmed ID: 16504630 Relation of Various Plasma Growth Factor Levels in Patients with Stable Angina Pectoris and Total Occlusion of a Coronary Artery to the Degree of Coronary Collaterals The American Journal of Cardiology. Feb, 2006 | Pubmed ID: 16461039 Nephrotoxicity of Low-osmolality Versus Iso-osmolality Contrast Agents: Impact of N-acetylcysteine Kidney International. Nov, 2005 | Pubmed ID: 16221226 Stem Cells for Cardiomyocyte Regeneration: State of the Art Annals of the New York Academy of Sciences. Jun, 2005 | Pubmed ID: 16093512 Stem Cells for Cardiac Repair: State of the Art Frontiers in Bioscience : a Journal and Virtual Library. 2005 | Pubmed ID: 15970570 Akt Mediates the Cross-talk Between Beta-adrenergic and Insulin Receptors in Neonatal Cardiomyocytes Circulation Research. Feb, 2005 | Pubmed ID: 15591229 Molecular Determinants of the Physiological Adaptation to Stress in the Cardiomyocyte: a Focus on AKT Journal of Molecular and Cellular Cardiology. Nov, 2004 | Pubmed ID: 15522267 Akt/protein Kinase B and Endothelial Nitric Oxide Synthase Mediate Muscular Neovascularization Induced by Tissue Kallikrein Gene Transfer Circulation. Sep, 2004 | Pubmed ID: 15364809 Transplantation of Low Dose CD34+KDR+ Cells Promotes Vascular and Muscular Regeneration in Ischemic Limbs FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2004 | Pubmed ID: 15345695 Heart Infarct in NOD-SCID Mice: Therapeutic Vasculogenesis by Transplantation of Human CD34+ Cells and Low Dose CD34+KDR+ Cells FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2004 | Pubmed ID: 15231728 Regulation of Cell Size and Contractile Function by AKT in Cardiomyocytes Annals of the New York Academy of Sciences. May, 2004 | Pubmed ID: 15201165 AKT Participates in Endothelial Dysfunction in Hypertension Circulation. Jun, 2004 | Pubmed ID: 15136501 A Nitric Oxide-releasing Derivative of Enalapril, NCX 899, Prevents Progressive Cardiac Dysfunction and Remodeling in Hamsters with Heart Failure FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2004 | Pubmed ID: 14734637 Mechanism of Enhanced Cardiac Function in Mice with Hypertrophy Induced by Overexpressed Akt The Journal of Biological Chemistry. Nov, 2003 | Pubmed ID: 13129932 C-Myc Oncoprotein: Cell Cycle-related Events and New Therapeutic Challenges in Cancer and Cardiovascular Diseases Cell Cycle (Georgetown, Tex.). Jul-Aug, 2003 | Pubmed ID: 12851483 Cardiomyocytes Methods in Molecular Biology (Clifton, N.J.). 2003 | Pubmed ID: 12824630 Expansion of Specific Alphabeta+ T-cell Subsets in the Myocardium of Patients with Myocarditis and Idiopathic Dilated Cardiomyopathy Associated with Coxsackievirus B Infection Human Immunology. Feb, 2003 | Pubmed ID: 12559622 P300/cAMP-response-element-binding-protein ('CREB')-binding Protein (CBP) Modulates Co-operation Between Myocyte Enhancer Factor 2A (MEF2A) and Thyroid Hormone Receptor-retinoid X Receptor The Biochemical Journal. Feb, 2003 | Pubmed ID: 12371907 TNF-alpha Signal Transduction in Rat Neonatal Cardiac Myocytes: Definition of Pathways Generating from the TNF-alpha Receptor FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2002 | Pubmed ID: 12409315 Akt Induces Enhanced Myocardial Contractility and Cell Size in Vivo in Transgenic Mice Proceedings of the National Academy of Sciences of the United States of America. Sep, 2002 | Pubmed ID: 12237475 ErbB2 is Essential in the Prevention of Dilated Cardiomyopathy Nature Medicine. May, 2002 | Pubmed ID: 11984589 Efficacy and Age-related Effects of Nitric Oxide-releasing Aspirin on Experimental Restenosis Proceedings of the National Academy of Sciences of the United States of America. Feb, 2002 | Pubmed ID: 11818533 Generering av Human Cardiomyocytes: differentiering protokoll från Feeder-fria mänskliga inducerade pluripotenta stamceller Elisa Di Pasquale1,2, Belle Song1, Gianluigi Condorelli1 1Humanitas Clinical and Research Center, Italy, 2Institute of Genetic and Biomedical Research (IRGB), National Research Council (CNR) JoVE 50429 Biology
Generering av Human Cardiomyocytes: differentiering protokoll från Feeder-fria mänskliga inducerade pluripotenta stamceller Elisa Di Pasquale1,2, Belle Song1, Gianluigi Condorelli1 1Humanitas Clinical and Research Center, Italy, 2Institute of Genetic and Biomedical Research (IRGB), National Research Council (CNR) JoVE 50429 Biology