Haiyong Han Molecular Medicine Division Translational Genomics Research Institute Biography Publications Institution JoVE Articles Haiyong Han has not added a biography. If you are Haiyong Han and would like to personalize this page please email our Author Liaison for assistance. Publications Clinical Study of Genomic Drivers in Pancreatic Ductal Adenocarcinoma British Journal of Cancer. Aug, 2017 | Pubmed ID: 28720843 Blocking Nerve Growth Factor Signaling Reduces the Neural Invasion Potential of Pancreatic Cancer Cells PloS One. 2016 | Pubmed ID: 27792755 Adenosquamous Carcinoma of the Pancreas: Molecular Characterization of 23 Patients Along with a Literature Review World Journal of Gastrointestinal Oncology. Sep, 2015 | Pubmed ID: 26380056 Orchestrating the Tumor Microenvironment to Improve Survival for Patients With Pancreatic Cancer: Normalization, Not Destruction Cancer Journal (Sudbury, Mass.). Jul-Aug, 2015 | Pubmed ID: 26222082 Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2015 | Pubmed ID: 25695692 Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma PLoS Genetics. Feb, 2014 | Pubmed ID: 24550739 Therapeutic Melting Pot of Never in Mitosis Gene a Related Kinase 2 (Nek2): a Perspective on Nek2 As an Oncology Target and Recent Advancements in Nek2 Small Molecule Inhibition Journal of Medicinal Chemistry. Jul, 2014 | Pubmed ID: 24517277 Discrimination Between Adenocarcinoma and Normal Pancreatic Ductal Fluid by Proteomic and Glycomic Analysis Journal of Proteome Research. Feb, 2014 | Pubmed ID: 24328148 Isolation and Characterization of Muscle Fatigue Substance with Anti-tumor Activities Journal of Cancer. 2013 | Pubmed ID: 23678371 SnapShot: Pancreatic Cancer Cancer Cell. Mar, 2013 | Pubmed ID: 23518352 Tumor-stromal Interactions in Pancreatic Cancer Critical Reviews in Oncogenesis. 2013 | Pubmed ID: 23237556 Characterization of a Membrane-active Anti-tumor Agent, UA8967 Investigational New Drugs. Jun, 2013 | Pubmed ID: 23179338 Genome-wide Characterization of Pancreatic Adenocarcinoma Patients Using Next Generation Sequencing PloS One. 2012 | Pubmed ID: 23071490 Specification, Annotation, Visualization and Simulation of a Large Rule-based Model for ERBB Receptor Signaling BMC Systems Biology. Aug, 2012 | Pubmed ID: 22913808 Down-regulation of Yes Associated Protein 1 Expression Reduces Cell Proliferation and Clonogenicity of Pancreatic Cancer Cells PloS One. 2012 | Pubmed ID: 22396793 Molecular Characterization of a Patient's Small Cell Carcinoma of the Ovary of the Hypercalcemic Type Journal of Cancer. 2012 | Pubmed ID: 22315651 Preclinical Investigation of Nanoparticle Albumin-bound Paclitaxel As a Potential Treatment for Adrenocortical Cancer Annals of Surgery. Jan, 2012 | Pubmed ID: 22156929 Kinome-wide SiRNA Screening Identifies Molecular Targets Mediating the Sensitivity of Pancreatic Cancer Cells to Aurora Kinase Inhibitors Biochemical Pharmacology. Feb, 2012 | Pubmed ID: 22100984 Targeting the Tumor Microenvironment in Cancer: Why Hyaluronidase Deserves a Second Look Cancer Discovery. Sep, 2011 | Pubmed ID: 22053288 Parallel Screening of FDA-approved Antineoplastic Drugs for Identifying Sensitizers of TRAIL-induced Apoptosis in Cancer Cells BMC Cancer. 2011 | Pubmed ID: 22044796 Perineural Invasion and Associated Pain in Pancreatic Cancer Nature Reviews. Cancer. Sep, 2011 | Pubmed ID: 21941281 Synergistic Effect Between Erlotinib and MEK Inhibitors in KRAS Wild-type Human Pancreatic Cancer Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2011 | Pubmed ID: 21385921 Cell Cycle Arrest and Apoptosis Induction by an Anticancer Chalcone Epoxide Archiv Der Pharmazie. Aug, 2010 | Pubmed ID: 20726006 Identification of Novel Pancreatic Adenocarcinoma Cell-surface Targets by Gene Expression Profiling and Tissue Microarray Biochemical Pharmacology. Sep, 2010 | Pubmed ID: 20510208 Identification of Pancreatic Cancer-specific Cell-surface Markers for Development of Targeting Ligands Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20217597 Validation of TPX2 As a Potential Therapeutic Target in Pancreatic Cancer Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2009 | Pubmed ID: 19861455 Enhanced Targeting with Heterobivalent Ligands Molecular Cancer Therapeutics. Aug, 2009 | Pubmed ID: 19671749 Characterization of Novel Diaryl Oxazole-based Compounds As Potential Agents to Treat Pancreatic Cancer The Journal of Pharmacology and Experimental Therapeutics. Nov, 2009 | Pubmed ID: 19657049 Identification and Characterization of a Novel Anticancer Agent with Selectivity Against Deleted in Pancreatic Cancer Locus 4 (DPC4)-deficient Pancreatic and Colon Cancer Cells Pancreas. Jul, 2009 | Pubmed ID: 19276868 UA62784, a Novel Inhibitor of Centromere Protein E Kinesin-like Protein Molecular Cancer Therapeutics. Jan, 2009 | Pubmed ID: 19139111 Copy Number Alterations in Pancreatic Cancer Identify Recurrent PAK4 Amplification Cancer Biology & Therapy. Nov, 2008 | Pubmed ID: 18836286 Pdx-1-driven Overexpression of Aurora a Kinase Induces Mild Ductal Dysplasia of Pancreatic Ducts Near Islets in Transgenic Mice Pancreas. Oct, 2008 | Pubmed ID: 18815537 Gene Expression Profiling-based Identification of Cell-surface Targets for Developing Multimeric Ligands in Pancreatic Cancer Molecular Cancer Therapeutics. Sep, 2008 | Pubmed ID: 18765825 Identification of Thioredoxin-interacting Protein 1 As a Hypoxia-inducible Factor 1alpha-induced Gene in Pancreatic Cancer Pancreas. Mar, 2008 | Pubmed ID: 18376310 Small Interfering RNA-mediated Knockdown of PRL Phosphatases Results in Altered Akt Phosphorylation and Reduced Clonogenicity of Pancreatic Cancer Cells Molecular Cancer Therapeutics. Jan, 2008 | Pubmed ID: 18187808 Identification of a Novel Inhibitor of Urokinase-type Plasminogen Activator Molecular Cancer Therapeutics. Apr, 2007 | Pubmed ID: 17431113 Comparing Aurora A and Aurora B As Molecular Targets for Growth Inhibition of Pancreatic Cancer Cells Molecular Cancer Therapeutics. Oct, 2006 | Pubmed ID: 17041088 Identification of an Agent Selectively Targeting DPC4 (deleted in Pancreatic Cancer Locus 4)-deficient Pancreatic Cancer Cells Cancer Research. Oct, 2006 | Pubmed ID: 17018631 Aurora Sheds Light on Head and Neck Squamous Cell Carcinoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2006 | Pubmed ID: 16951211 Identification of a Lead Small-molecule Inhibitor of the Aurora Kinases Using a Structure-assisted, Fragment-based Approach Molecular Cancer Therapeutics. Jul, 2006 | Pubmed ID: 16891462 Targeting Loss-of-function Mutations in Tumor-suppressor Genes As a Strategy for Development of Cancer Therapeutic Agents Seminars in Oncology. Aug, 2006 | Pubmed ID: 16890805 PRL Phosphatases As Potential Molecular Targets in Cancer Molecular Cancer Therapeutics. Nov, 2005 | Pubmed ID: 16275986 Hitting Multiple Targets with Multimeric Ligands Expert Opinion on Therapeutic Targets. Dec, 2004 | Pubmed ID: 15584863 Laminin-5 Beta3A Expression in LNCaP Human Prostate Carcinoma Cells Increases Cell Migration and Tumorigenicity Neoplasia (New York, N.Y.). Sep-Oct, 2004 | Pubmed ID: 15548355 Identification of Human Polo-like Kinase 1 As a Potential Therapeutic Target in Pancreatic Cancer Molecular Cancer Therapeutics. May, 2004 | Pubmed ID: 15141022 The Mitotic Serine Threonine Kinase, Aurora-2, is a Potential Target for Drug Development in Human Pancreatic Cancer Molecular Cancer Therapeutics. Apr, 2004 | Pubmed ID: 15078988 Targeting Aurora-2 Kinase in Cancer Molecular Cancer Therapeutics. Jun, 2003 | Pubmed ID: 12813139 The Cationic Porphyrin TMPyP4 Down-regulates C-MYC and Human Telomerase Reverse Transcriptase Expression and Inhibits Tumor Growth in Vivo Molecular Cancer Therapeutics. Jun, 2002 | Pubmed ID: 12479216 Identification of Differentially Expressed Genes in Pancreatic Cancer Cells Using CDNA Microarray Cancer Research. May, 2002 | Pubmed ID: 12019169 Hazırlık ve pankreas kanseri hücreleri ve fibroblastlar 3 boyutlu küresel ortak kültürlerin metabolik tahlil Pawan Noel1, Ruben Muñoz1, George W. Rogers2, Andrew Neilson2, Daniel D. Von Hoff1, Haiyong Han1 1Molecular Medicine Division, Translational Genomics Research Institute, 2Agilent Technologies JoVE 56081 Cancer Research
Hazırlık ve pankreas kanseri hücreleri ve fibroblastlar 3 boyutlu küresel ortak kültürlerin metabolik tahlil Pawan Noel1, Ruben Muñoz1, George W. Rogers2, Andrew Neilson2, Daniel D. Von Hoff1, Haiyong Han1 1Molecular Medicine Division, Translational Genomics Research Institute, 2Agilent Technologies JoVE 56081 Cancer Research