Hans-Achim Wagenknecht Institute of Organic Chemistry Karlsruhe Institute of Technology Biography Publications Institution JoVE Articles Hans-Achim Wagenknecht has not added a biography. If you are Hans-Achim Wagenknecht and would like to personalize this page please email our Author Liaison for assistance. Publications Two Wavelength-shifting Molecular Beacons for Simultaneous and Selective Imaging of Vesicular MiRNA-21 and MiRNA-31 in Living Cancer Cells Organic & Biomolecular Chemistry. Jun, 2016 | Pubmed ID: 27114268 Polarity Sensitive Bioorthogonally Applicable Far-Red Emitting Labels for Postsynthetic Nucleic Acid Labeling by Copper-Catalyzed and Copper-Free Cycloaddition Bioconjugate Chemistry. Feb, 2016 | Pubmed ID: 26786593 Thiazole Orange Dimers in DNA: Fluorescent Base Substitutions with Hybridization Readout Chemistry (Weinheim an Der Bergstrasse, Germany). Feb, 2016 | Pubmed ID: 26773846 A DNA-Fullerene Conjugate As a Template for Supramolecular Chromophore Assemblies: Towards DNA-Based Solar Cells Angewandte Chemie (International Ed. in English). Jan, 2016 | Pubmed ID: 26689149 Dynamic DNA Architectures: Spontaneous DNA Strand Exchange and Self-sorting Driven by Perylene Bisimide Interactions Chemical Communications (Cambridge, England). Nov, 2015 | Pubmed ID: 26419621 One-Dimensional Multichromophor Arrays Based on DNA: From Self-Assembly to Light-Harvesting Accounts of Chemical Research. Oct, 2015 | Pubmed ID: 26411920 Strand Displacement and Duplex Invasion into Double-stranded DNA by Pyrrolidinyl Peptide Nucleic Acids Organic & Biomolecular Chemistry. Sep, 2015 | Pubmed ID: 26223770 DNA-Based Oligochromophores As Light-Harvesting Systems Chemistry (Weinheim an Der Bergstrasse, Germany). Jun, 2015 | Pubmed ID: 26069203 Copper-Free Postsynthetic Labeling of Nucleic Acids by Means of Bioorthogonal Reactions Chembiochem : a European Journal of Chemical Biology. Jul, 2015 | Pubmed ID: 26063100 Development of a Wavelength-shifting Fluorescent Module for the Adenosine Aptamer Using Photostable Cyanine Dyes ChemistryOpen. Apr, 2015 | Pubmed ID: 25969803 Mesityl Phenanthroline-modified 2'-deoxyuridine for Heteroleptic Complexes in Metal Ion-mediated Assembly of DNA Dalton Transactions (Cambridge, England : 2003). Apr, 2015 | Pubmed ID: 25789449 Acceleration of Long-Range Photoinduced Electron Transfer Through DNA by Hydroxyquinolines As Artificial Base Pairs Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Jun, 2015 | Pubmed ID: 25784385 Mixed Non-covalent Assemblies of Ethynyl Nile Red and Ethynyl Pyrene Along Oligonucleotide Templates Organic & Biomolecular Chemistry. Jan, 2015 | Pubmed ID: 25374296 Nucleic Acid Chemistry Beilstein Journal of Organic Chemistry. 2014 | Pubmed ID: 25550760 "Photoclick" Postsynthetic Modification of DNA Angewandte Chemie (International Ed. in English). Dec, 2014 | Pubmed ID: 25359534 Synthesis and Optical Properties of Pyrrolidinyl Peptide Nucleic Acid Carrying a Clicked Nile Red Label Beilstein Journal of Organic Chemistry. 2014 | Pubmed ID: 25246975 2'-Deoxyuridine Conjugated with a Reactive Monobenzocyclooctyne As a DNA Building Block for Copper-free Click-type Postsynthetic Modification of DNA Chemical Communications (Cambridge, England). Oct, 2014 | Pubmed ID: 25112953 Bifunctional DNA Architectonics: Three-way Junctions with Sticky Perylene Bisimide Caps and a Central Metal Lock Chemistry (Weinheim an Der Bergstrasse, Germany). Sep, 2014 | Pubmed ID: 25098549 The Role of Duplex Stability for Wavelength-shifting Fluorescent DNA Probes: Energy Transfer Vs. Exciton Interactions in DNA "traffic Lights" Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology. Aug, 2014 | Pubmed ID: 25000916 The Base Discriminating Potential of Pyrrolidinyl PNA Demonstrated by Magnetic Fe(x)O(y) Particles Organic & Biomolecular Chemistry. Jun, 2014 | Pubmed ID: 24777755 Synthesis of DNA Conjugates with Metalated Tetracationic Porphyrins by Postsynthetic Cycloadditions Organic Letters. Mar, 2014 | Pubmed ID: 24606171 Photochemically Active Fluorophore-DNA/RNA Conjugates for Cellular Imaging of Nucleic Acids by Readout in Electron Microscopy ChemistryOpen. Aug, 2013 | Pubmed ID: 24551554 Synthesis and Evaluation of Cyanine-styryl Dyes with Enhanced Photostability for Fluorescent DNA Staining Organic & Biomolecular Chemistry. Nov, 2013 | Pubmed ID: 24088963 Conformational Control of Benzophenone-sensitized Charge Transfer in Dinucleotides Physical Chemistry Chemical Physics : PCCP. Nov, 2013 | Pubmed ID: 24084688 DNA-templated Formation of Fluorescent Self-assembly of Ethynyl Pyrenes Chemical Communications (Cambridge, England). Oct, 2013 | Pubmed ID: 23998185 Unraveling the Pathways to UVA-induced DNA Photodamage: (6-4) Photoproduct As a Potential "Trojan Horse" Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Oct, 2013 | Pubmed ID: 23897754 Development of a Metal-ion-mediated Base Pair for Electron Transfer in DNA Chemistry (Weinheim an Der Bergstrasse, Germany). Sep, 2013 | Pubmed ID: 23893654 DNA and RNA "traffic Lights": Synthetic Wavelength-shifting Fluorescent Probes Based on Nucleic Acid Base Substitutes for Molecular Imaging The Journal of Organic Chemistry. Aug, 2013 | Pubmed ID: 23796243 In-stem Labelling Allows Visualization of DNA Strand Displacements by Distinct Fluorescent Colour Change Organic & Biomolecular Chemistry. May, 2013 | Pubmed ID: 23558527 Fluorescence Quenching over Short Range in a Donor-DNA-acceptor System Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Apr, 2013 | Pubmed ID: 23532955 Synthesis and Redox and Photophysical Properties of Benzodifuran-spiropyran Ensembles Chemistry (Weinheim an Der Bergstrasse, Germany). May, 2013 | Pubmed ID: 23494841 Synthesis of 2'-O-propargyl Nucleoside Triphosphates for Enzymatic Oligonucleotide Preparation and "click" Modification of DNA with Nile Red As Fluorescent Probe Bioconjugate Chemistry. Mar, 2013 | Pubmed ID: 23425139 RNA "traffic Lights": an Analytical Tool to Monitor SiRNA Integrity ACS Chemical Biology. May, 2013 | Pubmed ID: 23402653 Synthesis of 4-aminophthalimide and 2,4-diaminopyrimidine C-nucleosides As Isosteric Fluorescent DNA Base Substitutes The Journal of Organic Chemistry. Mar, 2013 | Pubmed ID: 23383743 Energy-transfer-based Wavelength-shifting DNA Probes with "clickable" Cyanine Dyes Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology. May, 2013 | Pubmed ID: 23314253 Conformational Control of Dual Emission by Pyrrolidinyl PNA-DNA Hybrids ChemistryOpen. Aug, 2012 | Pubmed ID: 24551507 Diarylethene-modified Nucleotides for Switching Optical Properties in DNA Beilstein Journal of Organic Chemistry. 2012 | Pubmed ID: 23015841 Photoinduced Reductive Electron Transfer in LNA:DNA Hybrids: a Compromise Between Conformation and Base Stacking Angewandte Chemie (International Ed. in English). Oct, 2012 | Pubmed ID: 22945791 "DNA Traffic Lights": Concept of Wavelength-shifting DNA Probes and Application in an Aptasensor Chembiochem : a European Journal of Chemical Biology. May, 2012 | Pubmed ID: 22532374 A "clickable" Styryl Dye for Fluorescent DNA Labeling by Excitonic and Energy Transfer Interactions Chemistry (Weinheim an Der Bergstrasse, Germany). Jan, 2012 | Pubmed ID: 22223603 Metal-mediated DNA Assembly Using the Ethynyl Linked Terpyridine Ligand Organic & Biomolecular Chemistry. Jan, 2012 | Pubmed ID: 22089634 5-(Pyren-1-yl)uracil As a Base-discriminating Fluorescent Nucleobase in Pyrrolidinyl Peptide Nucleic Acids Chemistry, an Asian Journal. Dec, 2011 | Pubmed ID: 21976408 Polar Solvation Dynamics in Water and Methanol: Search for Molecularity Physical Chemistry Chemical Physics : PCCP. Oct, 2011 | Pubmed ID: 21887426 In-stem-labeled Molecular Beacons for Distinct Fluorescent Color Readout Angewandte Chemie (International Ed. in English). Aug, 2011 | Pubmed ID: 21717540 Ratiometric Molecular Beacons Based on the Perylene Bisimide As a Dimeric Internal DNA Base Substitution Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology. Aug, 2011 | Pubmed ID: 21547330 Assembly of DNA Triangles Mediated by Perylene Bisimide Caps Chemistry (Weinheim an Der Bergstrasse, Germany). Jun, 2011 | Pubmed ID: 21538613 4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene As a Bright Fluorescent Label for DNA The Journal of Organic Chemistry. Apr, 2011 | Pubmed ID: 21381720 Non-covalent Versus Covalent Control of Self-assembly and Chirality of Nile Red-modified Nucleoside and DNA Chemistry (Weinheim an Der Bergstrasse, Germany). Aug, 2010 | Pubmed ID: 20645354 New Far-red and Near-infrared Fluorescent Probes with Large Stokes Shifts for Dual Covalent Labeling of DNA Chemistry, an Asian Journal. Aug, 2010 | Pubmed ID: 20589826 Synthetic Incorporation of Nile Blue into DNA Using 2'-deoxyriboside Substitutes: Representative Comparison of (R)- and (S)-aminopropanediol As an Acyclic Linker Beilstein Journal of Organic Chemistry. 2010 | Pubmed ID: 20485595 Synthesis of Spiropyrans As Building Blocks for Molecular Switches and Dyads The Journal of Organic Chemistry. Apr, 2010 | Pubmed ID: 20334366 In Situ Azide Formation and "click" Reaction of Nile Red with DNA As an Alternative Postsynthetic Route Chemical Communications (Cambridge, England). Apr, 2010 | Pubmed ID: 20234915 Optical, Redox, and DNA-binding Properties of Phenanthridinium Chromophores: Elucidating the Role of the Phenyl Substituent for Fluorescence Enhancement of Ethidium in the Presence of DNA Chemistry (Weinheim an Der Bergstrasse, Germany). Mar, 2010 | Pubmed ID: 20175158 Imaging of RNA Delivery to Cells by Thiazole Orange As a Fluorescent RNA Base Substitution Organic & Biomolecular Chemistry. Mar, 2010 | Pubmed ID: 20165788 Red-white-blue Emission Switching Molecular Beacons: Ratiometric Multicolour DNA Hybridization Probes Organic & Biomolecular Chemistry. Feb, 2010 | Pubmed ID: 20090965 Photoinduced Short-range Electron Transfer in DNA with Fluorescent DNA Bases: Lessons from Ethidium and Thiazole Orange As Charge Donors Physical Chemistry Chemical Physics : PCCP. Jan, 2010 | Pubmed ID: 20024441 White-light-emitting DNA (WED) Chemistry (Weinheim an Der Bergstrasse, Germany). Sep, 2009 | Pubmed ID: 19681079 DNA As a Supramolecular Framework for the Helical Arrangements of Chromophores: Towards Photoactive DNA-based Nanomaterials Chemical Communications (Cambridge, England). May, 2009 | Pubmed ID: 19532903 Helical Arrangement of Porphyrins Along DNA: Towards Photoactive DNA-based Nanoarchitectures Angewandte Chemie (International Ed. in English). 2009 | Pubmed ID: 19259998 Fluorescent Color Readout of DNA Hybridization with Thiazole Orange As an Artificial DNA Base Angewandte Chemie (International Ed. in English). 2009 | Pubmed ID: 19229903 Comparison of a Nucleosidic Vs Non-nucleosidic Postsynthetic "click" Modification of DNA with Base-labile Fluorescent Probes Bioconjugate Chemistry. Mar, 2009 | Pubmed ID: 19220008 BODIPY-modified Uridines As Potential Fluorescent Probes for Nucleic Acids That Are Recognized by DNA-polymerases Nucleic Acids Symposium Series (2004). 2008 | Pubmed ID: 18776397 Fluorescent Hydrophobic Zippers Inside Duplex DNA: Interstrand Stacking of Perylene-3,4:9,10-tetracarboxylic Acid Bisimides As Artificial DNA Base Dyes Chemistry (Weinheim an Der Bergstrasse, Germany). 2008 | Pubmed ID: 18576414 Thiazole Orange and Cy3: Improvement of Fluorescent DNA Probes with Use of Short Range Electron Transfer The Journal of Organic Chemistry. Jun, 2008 | Pubmed ID: 18442293 Nucleotide Insertion and Bypass Synthesis of Pyrene- and BODIPY-modified Oligonucleotides by DNA Polymerases Chemical Communications (Cambridge, England). Mar, 2008 | Pubmed ID: 18338050 Perylene Bisimide Dimers As Fluorescent "glue" for DNA and for Base-mismatch Detection Angewandte Chemie (International Ed. in English). 2008 | Pubmed ID: 18288663 Fluorescent DNA Base Modifications and Substitutes: Multiple Fluorophore Labeling and the DETEQ Concept Annals of the New York Academy of Sciences. 2008 | Pubmed ID: 18096856 Phenothiazine As a Redox-active DNA Base Substitute: Comparison with Phenothiazine-modified Uridine Organic & Biomolecular Chemistry. Jan, 2008 | Pubmed ID: 18075645 Pyrene-modified Guanosine As Fluorescent Probe for DNA Modulated by Charge Transfer Bioorganic & Medicinal Chemistry. Jan, 2008 | Pubmed ID: 17509886 DNA Labelling Topologies for Monitoring DNA-protein Complex Formation by Fluorescence Anisotropy Nucleosides, Nucleotides & Nucleic Acids. 2007 | Pubmed ID: 18066831 Electron Transfer Processes in DNA: Mechanisms, Biological Relevance and Applications in DNA Analytics Natural Product Reports. Dec, 2006 | Pubmed ID: 17119642 Perylene-3,4:9,10-tetracarboxylic Acid Bisimide Dye As an Artificial DNA Base Surrogate Organic Letters. Sep, 2006 | Pubmed ID: 16956184 The Search for Single DNA Damage Among Millions of Base Pairs: DNA Glycosylases Trapped at Work Angewandte Chemie (International Ed. in English). Aug, 2006 | Pubmed ID: 16888824 Base Pair Motions Control the Rates and Distance Dependencies of Reductive and Oxidative DNA Charge Transfer Proceedings of the National Academy of Sciences of the United States of America. Jul, 2006 | Pubmed ID: 16801552 DNA As a Supramolecular Scaffold for the Helical Arrangement of a Stack of 1-ethynylpyrene Chromophores Organic & Biomolecular Chemistry. Jun, 2006 | Pubmed ID: 16729121 8-(Pyren-1-yl)-2'-deoxyguanosine As an Optical Probe for DNA Hybridization and for Charge Transfer with Small Peptides Bioorganic & Medicinal Chemistry Letters. Jun, 2006 | Pubmed ID: 16621544 Structure-sensitive and Self-assembled Helical Pyrene Array Based on DNA Architecture Angewandte Chemie (International Ed. in English). May, 2006 | Pubmed ID: 16619327 Electron Transfer Chemistry Between DNA and DNA-binding Tripeptides Biochemistry. Sep, 2005 | Pubmed ID: 16128576 1-ethynylpyrene-modified Guanine and Cytosine As Optical Labels for DNA Hybridization Organic & Biomolecular Chemistry. Jun, 2005 | Pubmed ID: 15917887 Real-time Spectroscopic and Chemical Probing of Reductive Electron Transfer in DNA Angewandte Chemie (International Ed. in English). Mar, 2005 | Pubmed ID: 15742326 Reductive Electron Transfer in Phenothiazine-modified DNA is Dependent on the Base Sequence Chemistry (Weinheim an Der Bergstrasse, Germany). Mar, 2005 | Pubmed ID: 15685707 Detection of Single Base Mismatches and Abasic Sites Using Phenanthridinium As an Artificial DNA Base and Charge Donor Organic & Biomolecular Chemistry. Jan, 2005 | Pubmed ID: 15602596 Ultrafast Proton-coupled Electron-transfer Dynamics in Pyrene-modified Pyrimidine Nucleosides: Model Studies Towards an Understanding of Reductive Electron Transport in DNA Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. May, 2004 | Pubmed ID: 15179723 1-Ethynylpyrene As a Tunable and Versatile Molecular Beacon for DNA Chembiochem : a European Journal of Chemical Biology. Jun, 2004 | Pubmed ID: 15174171 Phenanthridinium As an Artificial Base and Charge Donor in DNA Angewandte Chemie (International Ed. in English). Mar, 2004 | Pubmed ID: 15054791 Synthesis of DNA with Phenanthridinium As an Artificial DNA Base The Journal of Organic Chemistry. Feb, 2004 | Pubmed ID: 14750800 Pyrene As a Fluorescent Probe for DNA Base Radicals Chemical Communications (Cambridge, England). Aug, 2003 | Pubmed ID: 12932012 Metal-mediated DNA Base Pairing and Metal Arrays in Artificial DNA: Towards New Nanodevices Angewandte Chemie (International Ed. in English). Jul, 2003 | Pubmed ID: 12876728 Reductive Electron Transfer and Transport of Excess Electrons in DNA Angewandte Chemie (International Ed. in English). Jun, 2003 | Pubmed ID: 12800162 Exciton and Excimer Formation in DNA at Room Temperature Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Aug, 2002 | Pubmed ID: 12503153 Electron Injection into DNA: Synthesis and Spectroscopic Properties of Pyrenyl-modified Oligonucleotides Chemistry (Weinheim an Der Bergstrasse, Germany). Nov, 2002 | Pubmed ID: 12397589 A Model Nucleoside for Electron Injection into DNA: 5-pyrenyl-2'-deoxyribose Angewandte Chemie (International Ed. in English). Aug, 2002 | Pubmed ID: 12203430 סינתזה של בדיקות הכלאה DNA הסטה אורך גל על ידי שימוש photostable Cyanine צבעים Stefanie Arndt*1, Heidi-Kristin Walter*1, Hans-Achim Wagenknecht1 1Institute of Organic Chemistry, Karlsruhe Institute of Technology Biology
סינתזה של בדיקות הכלאה DNA הסטה אורך גל על ידי שימוש photostable Cyanine צבעים Stefanie Arndt*1, Heidi-Kristin Walter*1, Hans-Achim Wagenknecht1 1Institute of Organic Chemistry, Karlsruhe Institute of Technology Biology