Harrie Weinans Department of Biomechanical Engineering, Faculty of Mechanical, Maritime, and Materials Engineering Delft University of Technology (TU Delft) Biography Publications Institution JoVE Articles Harrie Weinans has not added a biography. If you are Harrie Weinans and would like to personalize this page please email our Author Liaison for assistance. Publications Solute Transport at the Interface of Cartilage and Subchondral Bone Plate: Effect of Micro-architecture Journal of Biomechanics. Feb, 2017 | Pubmed ID: 28063646 Degradation, Intra-articular Retention and Biocompatibility of Monospheres Composed of [PDLLA-PEG-PDLLA]-b-PLLA Multi-block Copolymers Acta Biomaterialia. Jan, 2017 | Pubmed ID: 27816621 Groove Model of Tibia-femoral Osteoarthritis in the Rat Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Mar, 2017 | Pubmed ID: 27183198 Neutral Solute Transport Across Osteochondral Interface: A Finite Element Approach Journal of Biomechanics. Dec, 2016 | Pubmed ID: 27793406 Isolated Effects of External Bath Osmolality, Solute Concentration, and Electrical Charge on Solute Transport Across Articular Cartilage Medical Engineering & Physics. Dec, 2016 | Pubmed ID: 27720635 Application of Multiphysics Models to Efficient Design of Experiments of Solute Transport Across Articular Cartilage Computers in Biology and Medicine. Nov, 2016 | Pubmed ID: 27673491 Guidelines for an Optimized Indentation Protocol for Measurement of Cartilage Stiffness: The Effects of Spatial Variation and Indentation Parameters Journal of Biomechanics. Oct, 2016 | Pubmed ID: 27660171 Combined Inverse-forward Artificial Neural Networks for Fast and Accurate Estimation of the Diffusion Coefficients of Cartilage Based on Multi-physics Models Journal of Biomechanics. Sep, 2016 | Pubmed ID: 27393413 Multiphasic Modeling of Charged Solute Transport Across Articular Cartilage: Application of Multi-zone Finite-bath Model Journal of Biomechanics. Jun, 2016 | Pubmed ID: 27033729 Osteophilic Properties of Bone Implant Surface Modifications in a Cassette Model on a Decorticated Goat Spinal Transverse Process Acta Biomaterialia. 06, 2016 | Pubmed ID: 27019145 Determination of the Mechanical and Physical Properties of Cartilage by Coupling Poroelastic-based Finite Element Models of Indentation with Artificial Neural Networks Journal of Biomechanics. Mar, 2016 | Pubmed ID: 26944689 Is T1ρ Mapping an Alternative to Delayed Gadolinium-enhanced MR Imaging of Cartilage in the Assessment of Sulphated Glycosaminoglycan Content in Human Osteoarthritic Knees? An in Vivo Validation Study Radiology. May, 2016 | Pubmed ID: 26588020 What Causes Cam Deformity and Femoroacetabular Impingement: Still Too Many Questions to Provide Clear Answers British Journal of Sports Medicine. Mar, 2016 | Pubmed ID: 26486586 Femoroacetabular Impingement: What is Its Link with Osteoarthritis? British Journal of Sports Medicine. Aug, 2016 | Pubmed ID: 26109013 Triamcinolone Acetonide Activates an Anti-inflammatory and Folate Receptor-positive Macrophage That Prevents Osteophytosis in Vivo Arthritis Research & Therapy. Dec, 2015 | Pubmed ID: 26637220 Validation of Statistical Shape Modelling to Predict Hip Osteoarthritis in Females: Data from Two Prospective Cohort Studies (Cohort Hip and Cohort Knee and Chingford) Rheumatology (Oxford, England). Nov, 2015 | Pubmed ID: 26139655 Revival of Pure Titanium for Dynamically Loaded Porous Implants Using Additive Manufacturing Materials Science & Engineering. C, Materials for Biological Applications. Sep, 2015 | Pubmed ID: 26046272 Distinct Subtypes of Knee Osteoarthritis: Data from the Osteoarthritis Initiative Rheumatology (Oxford, England). Sep, 2015 | Pubmed ID: 25882850 Osteostatin-coated Porous Titanium Can Improve Early Bone Regeneration of Cortical Bone Defects in Rats Tissue Engineering. Part A. May, 2015 | Pubmed ID: 25627039 Achilles Tendons in People with Type 2 Diabetes Show Mildly Compromised Structure: an Ultrasound Tissue Characterisation Study British Journal of Sports Medicine. Aug, 2015 | Pubmed ID: 25586910 Patient-specific Bone Modeling and Analysis: the Role of Integration and Automation in Clinical Adoption Journal of Biomechanics. Mar, 2015 | Pubmed ID: 25547022 Additively Manufactured Porous Tantalum Implants Acta Biomaterialia. Mar, 2015 | Pubmed ID: 25500631 Quarter-millimeter-resolution Molecular Mouse Imaging with U-SPECT⁺ Molecular Imaging. 2014 | Pubmed ID: 25429783 Full-field Strain Measurement During Mechanical Testing of the Human Femur at Physiologically Relevant Strain Rates Journal of Biomechanical Engineering. Nov, 2014 | Pubmed ID: 25162941 Release Behavior and Intra-articular Biocompatibility of Celecoxib-loaded Acetyl-capped PCLA-PEG-PCLA Thermogels Biomaterials. Sep, 2014 | Pubmed ID: 24952978 Mesenchymal Stem Cells Reduce Pain but Not Degenerative Changes in a Mono-iodoacetate Rat Model of Osteoarthritis Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Sep, 2014 | Pubmed ID: 24839120 Delayed Gadolinium-enhanced MRI of the Meniscus (dGEMRIM) in Patients with Knee Osteoarthritis: Relation with Meniscal Degeneration on Conventional MRI, Reproducibility, and Correlation with DGEMRIC European Radiology. Sep, 2014 | Pubmed ID: 24816941 Bone Regeneration Performance of Surface-treated Porous Titanium Biomaterials. Aug, 2014 | Pubmed ID: 24811260 A Cam Deformity is Gradually Acquired During Skeletal Maturation in Adolescent and Young Male Soccer Players: a Prospective Study with Minimum 2-year Follow-up The American Journal of Sports Medicine. Apr, 2014 | Pubmed ID: 24585362 Effects of Densitometry, Material Mapping and Load Estimation Uncertainties on the Accuracy of Patient-specific Finite-element Models of the Scapula Journal of the Royal Society, Interface. Apr, 2014 | Pubmed ID: 24522784 Increased Physical Activity Severely Induces Osteoarthritic Changes in Knee Joints with Papain Induced Sulfate-glycosaminoglycan Depleted Cartilage Arthritis Research & Therapy. Jan, 2014 | Pubmed ID: 24472689 Statistical Shape and Appearance Models of Bones Bone. Mar, 2014 | Pubmed ID: 24334169 Inflammatory Response and Bone Healing Capacity of Two Porous Calcium Phosphate Ceramics in Critical Size Cortical Bone Defects Journal of Biomedical Materials Research. Part A. May, 2014 | Pubmed ID: 23733500 Delayed Gadolinium-enhanced MRI of Cartilage (dGEMRIC) Shows No Change in Cartilage Structural Composition After Viscosupplementation in Patients with Early-stage Knee Osteoarthritis PloS One. 2013 | Pubmed ID: 24223194 Sustained Release of BMP-2 in Bioprinted Alginate for Osteogenicity in Mice and Rats PloS One. 2013 | Pubmed ID: 23977328 Subject-specific Modeling of the Scapula Bone Tissue Adaptation Journal of Biomechanics. Sep, 2013 | Pubmed ID: 23938055 In Situ Forming Acyl-capped PCLA-PEG-PCLA Triblock Copolymer Based Hydrogels Biomaterials. Oct, 2013 | Pubmed ID: 23891396 Cam Impingement of the Hip: a Risk Factor for Hip Osteoarthritis Nature Reviews. Rheumatology. 10, 2013 | Pubmed ID: 23881070 Properties of Commonly Used Calcium Phosphate Cements in Trauma and Orthopaedic Surgery Injury. Oct, 2013 | Pubmed ID: 23876622 Enhanced Bone Regeneration of Cortical Segmental Bone Defects Using Porous Titanium Scaffolds Incorporated with Colloidal Gelatin Gels for Time- and Dose-controlled Delivery of Dual Growth Factors Tissue Engineering. Part A. Dec, 2013 | Pubmed ID: 23822814 Repeatability of Digital Image Correlation for Measurement of Surface Strains in Composite Long Bones Journal of Biomechanics. Jul, 2013 | Pubmed ID: 23791085 Hsp90 Inhibition Protects Against Biomechanically Induced Osteoarthritis in Rats Arthritis and Rheumatism. Aug, 2013 | Pubmed ID: 23666904 Patient-specific Finite Element Modeling of Bones Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine. Apr, 2013 | Pubmed ID: 23637222 Physiological Effects of Oral Glucosamine on Joint Health: Current Status and Consensus on Future Research Priorities BMC Research Notes. Mar, 2013 | Pubmed ID: 23531101 Experimental Validation of Finite Element Model for Proximal Composite Femur Using Optical Measurements Journal of the Mechanical Behavior of Biomedical Materials. May, 2013 | Pubmed ID: 23510970 Full-field Strain Measurement and Fracture Analysis of Rat Femora in Compression Test Journal of Biomechanics. Apr, 2013 | Pubmed ID: 23510907 Selective Laser Melting-produced Porous Titanium Scaffolds Regenerate Bone in Critical Size Cortical Bone Defects Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. May, 2013 | Pubmed ID: 23255164 Unfocused Extracorporeal Shock Waves Induce Anabolic Effects in Osteoporotic Rats Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. May, 2013 | Pubmed ID: 23239548 Image Registration Improves Human Knee Cartilage T1 Mapping with Delayed Gadolinium-enhanced MRI of Cartilage (dGEMRIC) European Radiology. Jan, 2013 | Pubmed ID: 22865226 Cam Impingement Causes Osteoarthritis of the Hip: a Nationwide Prospective Cohort Study (CHECK) Annals of the Rheumatic Diseases. Jun, 2013 | Pubmed ID: 22730371 Estimation of 3D Rotation of Femur in 2D Hip Radiographs Journal of Biomechanics. Aug, 2012 | Pubmed ID: 22796003 Computational Load Estimation of the Femur Journal of the Mechanical Behavior of Biomedical Materials. Jun, 2012 | Pubmed ID: 22520423 Age-related Skeletal Dynamics and Decrease in Bone Strength in DNA Repair Deficient Male Trichothiodystrophy Mice PloS One. 2012 | Pubmed ID: 22506075 Periarticular Bone Changes in Osteoarthritis HSS Journal : the Musculoskeletal Journal of Hospital for Special Surgery. Feb, 2012 | Pubmed ID: 22423223 The Development of Cam-type Deformity in Adolescent and Young Male Soccer Players The American Journal of Sports Medicine. May, 2012 | Pubmed ID: 22415206 Systemic Treatment with Pulsed Electromagnetic Fields Do Not Affect Bone Microarchitecture in Osteoporotic Rats International Orthopaedics. Jul, 2012 | Pubmed ID: 22249842 Inhibiting Calcineurin Activity Under Physiologic Tonicity Elevates Anabolic but Suppresses Catabolic Chondrocyte Markers Arthritis and Rheumatism. Jun, 2012 | Pubmed ID: 22231955 Bone Remodelling Around a Cementless Glenoid Component Biomechanics and Modeling in Mechanobiology. Jul, 2012 | Pubmed ID: 22109099 Tendon Structure's Lack of Relation to Clinical Outcome After Eccentric Exercises in Chronic Midportion Achilles Tendinopathy Journal of Sport Rehabilitation. Feb, 2012 | Pubmed ID: 22100744 Bone Fragility and Decline in Stem Cells in Prematurely Aging DNA Repair Deficient Trichothiodystrophy Mice Age (Dordrecht, Netherlands). Aug, 2012 | Pubmed ID: 21814739 Low-magnitude Whole Body Vibration Does Not Affect Bone Mass but Does Affect Weight in Ovariectomized Rats Journal of Bone and Mineral Metabolism. Jan, 2012 | Pubmed ID: 21773704 Platelet-rich Plasma Releasate Inhibits Inflammatory Processes in Osteoarthritic Chondrocytes The American Journal of Sports Medicine. Nov, 2011 | Pubmed ID: 21856929 One-year Follow-up of Platelet-rich Plasma Treatment in Chronic Achilles Tendinopathy: a Double-blind Randomized Placebo-controlled Trial The American Journal of Sports Medicine. Aug, 2011 | Pubmed ID: 21602565 Quantifying Osteoarthritic Cartilage Changes Accurately Using in Vivo MicroCT Arthrography in Three Etiologically Distinct Rat Models Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Nov, 2011 | Pubmed ID: 21520262 Imaging of Activated Macrophages in Experimental Osteoarthritis Using Folate-targeted Animal Single-photon-emission Computed Tomography/computed Tomography Arthritis and Rheumatism. Jul, 2011 | Pubmed ID: 21437875 Femoral Component Neck Fracture After Failed Hip Resurfacing Arthroplasty The Journal of Arthroplasty. Dec, 2011 | Pubmed ID: 21397452 Clinically Translatable Cell Tracking and Quantification by MRI in Cartilage Repair Using Superparamagnetic Iron Oxides PloS One. Feb, 2011 | Pubmed ID: 21373640 Osteoarthritis Induction Leads to Early and Temporal Subchondral Plate Porosity in the Tibial Plateau of Mice: an in Vivo Microfocal Computed Tomography Study Arthritis and Rheumatism. Sep, 2011 | Pubmed ID: 21360519 Microstructure and Biomechanical Characteristics of Bone Substitutes for Trauma and Orthopaedic Surgery BMC Musculoskeletal Disorders. Feb, 2011 | Pubmed ID: 21288333 Analysis of Osteoarthritis in a Mouse Model of the Progeroid Human DNA Repair Syndrome Trichothiodystrophy Age (Dordrecht, Netherlands). Sep, 2011 | Pubmed ID: 20820927 Oestrogen is Important for Maintenance of Cartilage and Subchondral Bone in a Murine Model of Knee Osteoarthritis Arthritis Research & Therapy. 2010 | Pubmed ID: 20923566 Stimulation of Osteogenic Differentiation in Human Osteoprogenitor Cells by Pulsed Electromagnetic Fields: an in Vitro Study BMC Musculoskeletal Disorders. Aug, 2010 | Pubmed ID: 20731873 Physiological Tonicity Improves Human Chondrogenic Marker Expression Through Nuclear Factor of Activated T-cells 5 in Vitro Arthritis Research & Therapy. 2010 | Pubmed ID: 20492652 Similarities and Discrepancies in Subchondral Bone Structure in Two Differently Induced Canine Models of Osteoarthritis Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jul, 2010 | Pubmed ID: 20200954 Platelet-rich Plasma Injection for Chronic Achilles Tendinopathy: a Randomized Controlled Trial JAMA. Jan, 2010 | Pubmed ID: 20068208 Estrogen Modulates Iodoacetate-induced Gene Expression in Bovine Cartilage Explants Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. May, 2010 | Pubmed ID: 19953602 Stretch-induced Inhibition of Wnt/beta-catenin Signaling in Mineralizing Osteoblasts Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Mar, 2010 | Pubmed ID: 19780202 Calcineurin Inhibitors Promote Chondrogenic Marker Expression of Dedifferentiated Human Adult Chondrocytes Via Stimulation of Endogenous TGFbeta1 Production Tissue Engineering. Part A. Jan, 2010 | Pubmed ID: 19604038 Dual Energy X-ray Absorptiometry Analysis Contributes to the Prediction of Hip Osteoarthritis Progression Arthritis Research & Therapy. 2009 | Pubmed ID: 19883507 Chondrogenic Priming of Human Bone Marrow Stromal Cells: a Better Route to Bone Repair? Tissue Engineering. Part C, Methods. Jun, 2009 | Pubmed ID: 19505182 Unfocused Extracorporeal Shock Wave Therapy As Potential Treatment for Osteoporosis Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Nov, 2009 | Pubmed ID: 19441107 Control of Oxygen Tension and PH in a Bioreactor for Cartilage Tissue Engineering Bio-medical Materials and Engineering. 2008 | Pubmed ID: 19065034 Bone Resorption Inhibitor Alendronate Normalizes the Reduced Bone Thickness of TRPV5(-/-) Mice Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Nov, 2008 | Pubmed ID: 18597625 Single Versus Triple Daily Activation of the Distractor: No Significant Effects of Frequency of Distraction on Bone Regenerate Quantity and Architecture Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery. Apr, 2008 | Pubmed ID: 18359239 Effects of Iron Oxide Incorporation for Long Term Cell Tracking on MSC Differentiation in Vitro and in Vivo Biochemical and Biophysical Research Communications. May, 2008 | Pubmed ID: 18336785 Can Platelet-rich Plasma Enhance Tendon Repair? A Cell Culture Study The American Journal of Sports Medicine. Jun, 2008 | Pubmed ID: 18326832 Effect of Glucosamine Sulfate on Hip Osteoarthritis: a Randomized Trial Annals of Internal Medicine. Feb, 2008 | Pubmed ID: 18283204 A Role for Subchondral Bone Changes in the Process of Osteoarthritis; a Micro-CT Study of Two Canine Models BMC Musculoskeletal Disorders. Feb, 2008 | Pubmed ID: 18269731 Early Identification of Radiographic Osteoarthritis of the Hip Using an Active Shape Model to Quantify Changes in Bone Morphometric Features: Can Hip Shape Tell Us Anything About the Progression of Osteoarthritis? Arthritis and Rheumatism. Nov, 2007 | Pubmed ID: 17968890 Effects of Microarchitecture on Bone Strength Current Osteoporosis Reports. Jun, 2007 | Pubmed ID: 17521506 Intrinsic Differentiation Potential of Adolescent Human Tendon Tissue: an In-vitro Cell Differentiation Study BMC Musculoskeletal Disorders. Feb, 2007 | Pubmed ID: 17319938 Histogram-based Selective Deblurring to Improve Computed Tomography Imaging of Calcifications Investigative Radiology. Jan, 2007 | Pubmed ID: 17213744 The Use of Micro-CT to Study Bone Architecture Dynamics Noninvasively Drug Discovery Today. Technologies. 2006 | Pubmed ID: 24980410 The Novel Vitamin D Analog ZK191784 As an Intestine-specific Vitamin D Antagonist FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2006 | Pubmed ID: 17012263 Prediction of Torsional Failure in 22 Cadaver Femora with and Without Simulated Subtrochanteric Metastatic Defects: a CT Scan-based Finite Element Analysis Acta Orthopaedica. Jun, 2006 | Pubmed ID: 16819688 Stretch-induced Modulation of Matrix Metalloproteinases in Mineralizing Osteoblasts Via Extracellular Signal-regulated Kinase-1/2 Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Jul, 2006 | Pubmed ID: 16705736 Bone Loss Dynamics Result in Trabecular Alignment in Aging and Ovariectomized Rats Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. May, 2006 | Pubmed ID: 16583450 Ultrasonic Characterization of Human Trabecular Bone Microstructure Physics in Medicine and Biology. Mar, 2006 | Pubmed ID: 16510968 Long-term Serotonin Administration Leads to Higher Bone Mineral Density, Affects Bone Architecture, and Leads to Higher Femoral Bone Stiffness in Rats Journal of Cellular Biochemistry. Apr, 2006 | Pubmed ID: 16329113 Identification of Acid-sensing Ion Channels in Bone Biochemical and Biophysical Research Communications. Nov, 2005 | Pubmed ID: 16185661 Hypervitaminosis D Mediates Compensatory Ca2+ Hyperabsorption in TRPV5 Knockout Mice Journal of the American Society of Nephrology : JASN. Nov, 2005 | Pubmed ID: 16148038 Lordotic Vertebrae in Sea Bass (Dicentrarchus Labrax L.) Are Adapted to Increased Loads Journal of Biomechanics. Jun, 2005 | Pubmed ID: 15863108 The Effect of Glucosamine Sulphate on Osteoarthritis: Design of a Long-term Randomised Clinical Trial [ISRCTN54513166] BMC Musculoskeletal Disorders. Apr, 2005 | Pubmed ID: 15850497 Prediction of Density and Mechanical Properties of Human Trabecular Bone in Vitro by Using Ultrasound Transmission and Backscattering Measurements at 0.2-6.7 MHz Frequency Range Physics in Medicine and Biology. Apr, 2005 | Pubmed ID: 15815086 Improved Cartilage Integration and Interfacial Strength After Enzymatic Treatment in a Cartilage Transplantation Model Arthritis Research & Therapy. 2004 | Pubmed ID: 15380046 An Improved Segmentation Method for in Vivo MicroCT Imaging Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Oct, 2004 | Pubmed ID: 15355559 Living Cells in 1 of 2 Frozen Femoral Heads Acta Orthopaedica Scandinavica. Dec, 2003 | Pubmed ID: 14763695 The Dependence of the Elastic Properties of Osteoporotic Cancellous Bone on Volume Fraction and Fabric Journal of Biomechanics. Oct, 2003 | Pubmed ID: 14499295 An Experimental and Finite Element Protocol to Investigate the Transport of Neutral and Charged Solutes across Articular Cartilage Vahid Arbabi*1,2, Behdad Pouran*1,2, Amir. A. Zadpoor1, Harrie Weinans1,2,3 1Department of Biomechanical Engineering, Faculty of Mechanical, Maritime, and Materials Engineering, Delft University of Technology (TU Delft), 2Department of Orthopedics, UMC Utrecht, 3Department of Rheumatology, UMC Utrecht JoVE 54984 Bioengineering
An Experimental and Finite Element Protocol to Investigate the Transport of Neutral and Charged Solutes across Articular Cartilage Vahid Arbabi*1,2, Behdad Pouran*1,2, Amir. A. Zadpoor1, Harrie Weinans1,2,3 1Department of Biomechanical Engineering, Faculty of Mechanical, Maritime, and Materials Engineering, Delft University of Technology (TU Delft), 2Department of Orthopedics, UMC Utrecht, 3Department of Rheumatology, UMC Utrecht JoVE 54984 Bioengineering