Helmut Friess Department of Surgery, Klinikum rechts der Isar Technische Universität München Biography Publications Institution JoVE Articles Helmut Friess has not added a biography. If you are Helmut Friess and would like to personalize this page please email our Author Liaison for assistance. Publications Pancreatic Enzyme Replacement Therapy in Patients With Exocrine Pancreatic Insufficiency Due to Chronic Pancreatitis: A 1-Year Disease Management Study on Symptom Control and Quality of Life Pancreas. Apr, 2014 | Pubmed ID: 24717829 When to Perform a Pancreatoduodenectomy in the Absence of Positive Histology? A consensus Statement by the International Study Group of Pancreatic Surgery Surgery. Jan, 2014 | Pubmed ID: 24661765 Anti-platelet Factor 4/heparin Antibodies in Patients with Impaired Graft Function After Liver Transplantation Journal of Thrombosis and Haemostasis : JTH. Mar, 2014 | Pubmed ID: 24655935 Native Ureteropyelostomy: an Effective Therapy for Urinary Tract Complications Following Kidney Transplantation ANZ Journal of Surgery. Jan, 2014 | Pubmed ID: 24456401 Chronic CCl4 Intoxication Causes Liver and Bone Damage Similar to the Human Pathology of Hepatic Osteodystrophy: a Mouse Model to Analyse the Liver-bone Axis Archives of Toxicology. Apr, 2014 | Pubmed ID: 24381012 The Neurotrophic Factor Neurturin Contributes Toward an Aggressive Cancer Cell Phenotype, Neuropathic Pain and Neuronal Plasticity in Pancreatic Cancer Carcinogenesis. Jan, 2014 | Pubmed ID: 24067900 Evidence of Pancreatic Neuropathy and Neuropathic Pain in Hereditary Chronic Pancreatitis Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]. Nov-Dec, 2013 | Pubmed ID: 24280582 Impact of Preoperative Local Water-filtered Infrared A Irradiation on Postoperative Wound Healing: a Randomized Patient- and Observer-blinded Controlled Clinical Trial Annals of Surgery. Dec, 2013 | Pubmed ID: 24169161 Treatment Options in Painful Chronic Pancreatitis: a Systematic Review HPB : the Official Journal of the International Hepato Pancreato Biliary Association. Aug, 2013 | Pubmed ID: 24033614 Comparative Analysis of Different Transection Techniques in Minor and Major Hepatic Resections: a Prospective Cohort Study International Journal of Surgery (London, England). 2013 | Pubmed ID: 23994002 Mucinous and Signet-ring Cell Colorectal Cancers Differ from Classical Adenocarcinomas in Tumor Biology and Prognosis Annals of Surgery. Nov, 2013 | Pubmed ID: 23989057 Variants in CPA1 Are Strongly Associated with Early Onset Chronic Pancreatitis Nature Genetics. Oct, 2013 | Pubmed ID: 23955596 Cachexia in Patients with Chronic Pancreatitis and Pancreatic Cancer: Impact on Survival and Outcome Nutrition and Cancer. 2013 | Pubmed ID: 23909726 Procalcitonin Ratio As a Predictor of Successful Surgical Treatment of Severe Necrotizing Soft Tissue Infections American Journal of Surgery. Sep, 2013 | Pubmed ID: 23806825 Comparative Analysis of the Revenues of Pylorus-preserving Pancreatic Head Resections and Laparoscopic Cholecystectomies As Prototypic Surgical Procedures in the German Health-care System Langenbeck's Archives of Surgery / Deutsche Gesellschaft Für Chirurgie. Aug, 2013 | Pubmed ID: 23778973 Chylothorax After Esophagectomy for Cancer: Impact of the Surgical Approach and Neoadjuvant Treatment: Systematic Review and Institutional Analysis Surgical Endoscopy. Oct, 2013 | Pubmed ID: 23708712 Perineural Mast Cells Are Specifically Enriched in Pancreatic Neuritis and Neuropathic Pain in Pancreatic Cancer and Chronic Pancreatitis PloS One. 2013 | Pubmed ID: 23555989 Reperfusion of Liver Graft During Transplantation: Techniques Used in Transplant Centres Within Eurotransplant and Meta-analysis of the Literature Transplant International : Official Journal of the European Society for Organ Transplantation. May, 2013 | Pubmed ID: 23517278 Sorafenib Perpetuates Cellular Anticancer Effector Functions by Modulating the Crosstalk Between Macrophages and Natural Killer Cells Hepatology (Baltimore, Md.). Jun, 2013 | Pubmed ID: 23424039 Neural Plasticity in the Gastrointestinal Tract: Chronic Inflammation, Neurotrophic Signals, and Hypersensitivity Acta Neuropathologica. Apr, 2013 | Pubmed ID: 23417735 European Experts Consensus Statement on Cystic Tumours of the Pancreas Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. Sep, 2013 | Pubmed ID: 23415799 Extended Postinterventional Tumor Necrosis-implication for Outcome in Liver Transplant Patients with Advanced HCC PloS One. 2013 | Pubmed ID: 23349774 A Review of Computer-based Simulators for Ultrasound Training Simulation in Healthcare : Journal of the Society for Simulation in Healthcare. Apr, 2013 | Pubmed ID: 23334364 The Impact of MFG-E8 in Chronic Pancreatitis: Potential for Future Immunotherapy? BMC Gastroenterology. 2013 | Pubmed ID: 23324439 Independent Validation of a Prognostic Genomic Signature (ColoPrint) for Patients with Stage II Colon Cancer Annals of Surgery. Jun, 2013 | Pubmed ID: 23295318 Effect of Preoperative Radio(chemo)therapy on Long-term Functional Outcome in Rectal Cancer Patients: a Systematic Review and Meta-analysis Annals of Surgical Oncology. Jun, 2013 | Pubmed ID: 23269466 Toward Increased Autonomy in the Surgical OR: Needs, Requests, and Expectations Surgical Endoscopy. May, 2013 | Pubmed ID: 23239307 Prognostic Implications of the Seventh Edition of the International Union Against Cancer Classification for Patients with Gastric Cancer: the Western Experience of Patients Treated in a Single-center European Institution Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jan, 2013 | Pubmed ID: 23213098 The Severity of Neural Invasion is Associated with Shortened Survival in Colon Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2013 | Pubmed ID: 23147996 Heme Oxygenase 1-generated Carbon Monoxide and Biliverdin Attenuate the Course of Experimental Necrotizing Pancreatitis Pancreas. Mar, 2013 | Pubmed ID: 23000891 Clinical Trials in Gastric Cancer and the Future Journal of Surgical Oncology. Mar, 2013 | Pubmed ID: 22514058 Carcinogenesis, Prevention and Treatment of Colorectal Cancer--State of the Art 2012. Introduction Digestive Diseases (Basel, Switzerland). 2012 | Pubmed ID: 23207925 Integrative Marker Analysis Allows Risk Assessment for Metastasis in Stage II Colon Cancer Annals of Surgery. Nov, 2012 | Pubmed ID: 23095620 How Fibrosis Influences Imaging and Surgical Decisions in Pancreatic Cancer Frontiers in Physiology. 2012 | Pubmed ID: 23060813 Proposal for a Multifactorial Prognostic Score That Accurately Classifies 3 Groups of Gastric Carcinoma Patients with Different Outcomes After Neoadjuvant Chemotherapy and Surgery Annals of Surgery. Dec, 2012 | Pubmed ID: 22968067 Neuronal Plasticity in Chronic Pancreatitis is Mediated Via the Neurturin/GFRα2 Axis American Journal of Physiology. Gastrointestinal and Liver Physiology. Nov, 2012 | Pubmed ID: 22961804 Is There New Hope for Patients with Marginally Resectable Liver Malignancies World Journal of Gastrointestinal Surgery. Jul, 2012 | Pubmed ID: 22905283 The Actin Binding Protein Destrin is Associated with Growth and Perineural Invasion of Pancreatic Cancer Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]. Jul-Aug, 2012 | Pubmed ID: 22898637 Transarterial Chemoembolization of Liver Metastases As Symptomatic Therapy of Lipase Hypersecretion Syndrome Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Aug, 2012 | Pubmed ID: 22778324 Sexual and Relationship Functioning Before and After Renal Transplantation: a Descriptive Study with Patients and Partners Scandinavian Journal of Urology and Nephrology. Dec, 2012 | Pubmed ID: 22725101 The Role of Stroma in Pancreatic Cancer: Diagnostic and Therapeutic Implications Nature Reviews. Gastroenterology & Hepatology. Aug, 2012 | Pubmed ID: 22710569 Beyond Lactate: is There a Role for Serum Lactate Measurement in Diagnosing Acute Mesenteric Ischemia? Digestive Surgery. 2012 | Pubmed ID: 22699523 Design and Current Status of CONTINT: Continuous Versus Interrupted Abdominal Wall Closure After Emergency Midline Laparotomy - a Randomized Controlled Multicenter Trial [NCT00544583] Trials. May, 2012 | Pubmed ID: 22647387 Google Goes Cancer: Improving Outcome Prediction for Cancer Patients by Network-based Ranking of Marker Genes PLoS Computational Biology. 2012 | Pubmed ID: 22615549 Standard Abdominal Wound Edge Protection with Surgical Dressings Vs Coverage with a Sterile Circular Polyethylene Drape for Prevention of Surgical Site Infections (BaFO): Study Protocol for a Randomized Controlled Trial Trials. 2012 | Pubmed ID: 22587425 Heparin-induced Thrombocytopenia (HIT II) in Liver Transplant Recipients: a Retrospective Multivariate Analysis of Prognostic Factors Transplant International : Official Journal of the European Society for Organ Transplantation. Jul, 2012 | Pubmed ID: 22548256 Therapeutic Potential of the Chemokine-receptor Duo Fractalkine/CX3CR1: an Update Expert Opinion on Therapeutic Targets. Jun, 2012 | Pubmed ID: 22530606 Nerve-cancer Interactions in the Stromal Biology of Pancreatic Cancer Frontiers in Physiology. 2012 | Pubmed ID: 22529816 Multimodal Treatment Strategies for Locally Advanced Rectal Cancer Expert Review of Anticancer Therapy. Apr, 2012 | Pubmed ID: 22500685 Syndecan-2 Promotes Perineural Invasion and Cooperates with K-ras to Induce an Invasive Pancreatic Cancer Cell Phenotype Molecular Cancer. 2012 | Pubmed ID: 22471946 Tissue-based Proteomics Reveals FXYD3, S100A11 and GSTM3 As Novel Markers for Regional Lymph Node Metastasis in Colon Cancer The Journal of Pathology. Mar, 2012 | Pubmed ID: 22430872 Total Gastric Necrosis Subsequent to Acute Pancreatitis Pancreas. Mar, 2012 | Pubmed ID: 22343979 Educational and Training Aspects of New Surgical Techniques: Experience with the Endoscopic–laparoscopic Interdisciplinary Training Entity (ELITE) Model in Training for a Natural Orifice Translumenal Endoscopic Surgery (NOTES) Approach to Appendectomy Surgical Endoscopy. Aug, 2012 | Pubmed ID: 22286276 The Impact of the Activated Stroma on Pancreatic Ductal Adenocarcinoma Biology and Therapy Resistance Current Molecular Medicine. Mar, 2012 | Pubmed ID: 22272725 Tumor Classification of Six Common Cancer Types Based on Proteomic Profiling by MALDI Imaging Journal of Proteome Research. Mar, 2012 | Pubmed ID: 22224404 Mixed Antagonist Response and Sepsis Severity-dependent Dysbalance of Pro- and Anti-inflammatory Responses at the Onset of Postoperative Sepsis Immunobiology. Jun, 2012 | Pubmed ID: 22204813 Recruitment of Histone Deacetylases HDAC1 and HDAC2 by the Transcriptional Repressor ZEB1 Downregulates E-cadherin Expression in Pancreatic Cancer Gut. Mar, 2012 | Pubmed ID: 22147512 Adenocarcinomas of the Esophagogastric Junction Are More Likely to Respond to Preoperative Chemotherapy Than Distal Gastric Cancer Annals of Surgical Oncology. Jul, 2012 | Pubmed ID: 22130620 StellaTUM: Current Consensus and Discussion on Pancreatic Stellate Cell Research Gut. Feb, 2012 | Pubmed ID: 22115911 Littoral Cell Angioma and Angiosarcoma of the Spleen: Report of Two Cases in Siblings and Review of the Literature Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Apr, 2012 | Pubmed ID: 22068970 Palliative Resections Versus Palliative Bypass Procedures in Pancreatic Cancer--a Systematic Review American Journal of Surgery. Apr, 2012 | Pubmed ID: 21872208 Patients with Non-[18 F]fludeoxyglucose-avid Advanced Hepatocellular Carcinoma on Clinical Staging May Achieve Long-term Recurrence-free Survival After Liver Transplantation Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Jan, 2012 | Pubmed ID: 21850692 Prolyl Hydroxylase-2 (PHD2) Exerts Tumor-suppressive Activity in Pancreatic Cancer Cancer. Feb, 2012 | Pubmed ID: 21792862 Real-time Monitoring for Detection of Retained Surgical Sponges and Team Motion in the Surgical Operation Room Using Radio-frequency-identification (RFID) Technology: a Preclinical Evaluation The Journal of Surgical Research. Jun, 2012 | Pubmed ID: 21571315 Palliative Interventional and Surgical Therapy for Unresectable Pancreatic Cancer Cancers. 2011 | Pubmed ID: 24212634 Enhanced Activity of Meprin-α, a Pro-migratory and Pro-angiogenic Protease, in Colorectal Cancer PloS One. 2011 | Pubmed ID: 22096485 Prediction of Prognosis is Not Improved by the Seventh and Latest Edition of the TNM Classification for Colorectal Cancer in a Single-center Collective Annals of Surgery. Nov, 2011 | Pubmed ID: 22042471 How to Classify Adenocarcinomas of the Esophagogastric Junction: As Esophageal or Gastric Cancer? The American Journal of Surgical Pathology. Oct, 2011 | Pubmed ID: 21934477 The Amount of Neoadjuvant Chemotherapy for Barrett's Carcinoma Does Not Correlate with Long-term Survival Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Oct, 2011 | Pubmed ID: 21811882 Tumor-specific Targeting of Pancreatic Cancer with Shiga Toxin B-subunit Molecular Cancer Therapeutics. Oct, 2011 | Pubmed ID: 21788400 (18)F-FDG PET-guided Salvage Neoadjuvant Radiochemotherapy of Adenocarcinoma of the Esophagogastric Junction: the MUNICON II Trial Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Aug, 2011 | Pubmed ID: 21764790 From Tissue Turnover to the Cell of Origin for Pancreatic Cancer Nature Reviews. Gastroenterology & Hepatology. Aug, 2011 | Pubmed ID: 21750515 Intestinal Obstruction from End-to-side or Side-to-side Anastomosis Made by a Circular Stapling Device The American Surgeon. May, 2011 | Pubmed ID: 21679605 Telomerase Gene Mutations Are Associated with Cirrhosis Formation Hepatology (Baltimore, Md.). May, 2011 | Pubmed ID: 21520174 Assessment of ErbB2 (Her2) in Oesophageal Adenocarcinomas: Summary of a Revised Immunohistochemical Evaluation System, Bright Field Double in Situ Hybridisation and Fluorescence in Situ Hybridisation Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Jul, 2011 | Pubmed ID: 21516080 Insulin-like Growth Factor Signaling As a Therapeutic Target in Pancreatic Cancer Anti-cancer Agents in Medicinal Chemistry. Jun, 2011 | Pubmed ID: 21492074 Significance of Histopathological Tumor Regression After Neoadjuvant Chemotherapy in Gastric Adenocarcinomas: a Summary of 480 Cases Annals of Surgery. May, 2011 | Pubmed ID: 21490451 Impact of CD39 and Purinergic Signalling on the Growth and Metastasis of Colorectal Cancer Purinergic Signalling. Jun, 2011 | Pubmed ID: 21484085 Clinical Significance of the Costimulatory Molecule B7-H1 in Barrett Carcinoma The Annals of Thoracic Surgery. Apr, 2011 | Pubmed ID: 21440117 Transgastric or Trans-sigmoidal? The Impact of the Choice of Access on Task Performance in Target Natural Orifice Translumenal Endoscopic Surgery Procedures Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A. Apr, 2011 | Pubmed ID: 21366439 Massive Intra-abdominal Bleeding Caused by Nontraumatic Rupture of a Vein in the Colorenal Ligament: Report of a Case Surgery Today. Mar, 2011 | Pubmed ID: 21365428 Pigment Epithelium-derived Factor Associates with Neuropathy and Fibrosis in Pancreatic Cancer The American Journal of Gastroenterology. May, 2011 | Pubmed ID: 21224836 Glutamate Increases Pancreatic Cancer Cell Invasion and Migration Via AMPA Receptor Activation and Kras-MAPK Signaling International Journal of Cancer. Journal International Du Cancer. Nov, 2011 | Pubmed ID: 21207374 Healing Occurs in Most Patients That Receive Endoscopic Stents for Anastomotic Leakage; Dislocation Remains a Problem Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Mar, 2011 | Pubmed ID: 21172455 Autoimmune Pancreatitis Complicated by Carcinoma of the Pancreatobiliary System: a Case Report and Review of the Literature Pancreas. Jan, 2011 | Pubmed ID: 21160372 Pain Mechanisms in Chronic Pancreatitis: of a Master and His Fire Langenbeck's Archives of Surgery / Deutsche Gesellschaft Für Chirurgie. Feb, 2011 | Pubmed ID: 21153480 Genetic Aberrations in Primary Esophageal Melanomas: Molecular Analysis of C-KIT, PDGFR, KRAS, NRAS and BRAF in a Series of 10 Cases Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Apr, 2011 | Pubmed ID: 21131919 Comparison of Different SUV-based Methods for Response Prediction to Neoadjuvant Radiochemotherapy in Locally Advanced Rectal Cancer by FDG-PET and MRI Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Oct, 2011 | Pubmed ID: 20936364 Variable Impact of CD39 in Experimental Murine Colitis Digestive Diseases and Sciences. May, 2011 | Pubmed ID: 20936356 Is Laparoscopic Colorectal Cancer Surgery Equal to Open Surgery? An Evidence Based Perspective World Journal of Gastrointestinal Surgery. Apr, 2010 | Pubmed ID: 21160858 B7-h3 and Its Role in Antitumor Immunity Clinical & Developmental Immunology. 2010 | Pubmed ID: 21127709 The Severity of Neural Invasion is a Crucial Prognostic Factor in Rectal Cancer Independent of Neoadjuvant Radiochemotherapy Annals of Surgery. Nov, 2010 | Pubmed ID: 21037435 Reduced Expression of the Membrane Skeleton Protein Beta1-spectrin (SPTBN1) is Associated with Worsened Prognosis in Pancreatic Cancer Histology and Histopathology. Dec, 2010 | Pubmed ID: 20886430 Interleukin-10 and -12 Predict Chemotherapy-associated Toxicity in Esophageal Adenocarcinoma Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Nov, 2010 | Pubmed ID: 20881642 Key Role of Phosphoinositide 3-kinase Class IB in Pancreatic Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2010 | Pubmed ID: 20876794 Biochemical and Biophysical Research Communications. Oct, 2010 | Pubmed ID: 20863812 Early Response Evaluation and Prediction in Neoadjuvant-treated Patients with Esophageal Cancer World Journal of Gastrointestinal Surgery. Nov, 2009 | Pubmed ID: 21160793 Simulabukspyttkjertel Neuroplasticity: Ihsan Ekin Demir1, Elke Tieftrunk1, Karl-Herbert Schäfer2, Helmut Friess1, Güralp O. Ceyhan1 1Department of Surgery, Klinikum rechts der Isar, Technische Universität München, 2Department of Biotechnology, University of Applied Sciences Kaiserslautern/Zweibrücken JoVE 51049 Medicine
Simulabukspyttkjertel Neuroplasticity: Ihsan Ekin Demir1, Elke Tieftrunk1, Karl-Herbert Schäfer2, Helmut Friess1, Güralp O. Ceyhan1 1Department of Surgery, Klinikum rechts der Isar, Technische Universität München, 2Department of Biotechnology, University of Applied Sciences Kaiserslautern/Zweibrücken JoVE 51049 Medicine