Henrik Hagberg Centre of Perinatal Medicine and Health, Institute of Clinical Sciences, Department of Obstetrics and Gynecology, Sahlgrenska Academy University of Gothenburg Biography Publications Institution JoVE Articles Henrik Hagberg has not added a biography. If you are Henrik Hagberg and would like to personalize this page please email our Author Liaison for assistance. Publications Neuro-Specific and Immuno-Inflammatory Biomarkers in Umbilical Cord Blood in Neonatal Hypoxic-Ischemic Encephalopathy Neonatology. 2024 | Pubmed ID: 37778335 Therapeutic Effect of Nicotinamide Mononucleotide for Hypoxic-Ischemic Brain Injury in Neonatal Mice ASN Neuro. 2023 | Pubmed ID: 37787108 A Follow Up on the Feasibility After National Implementation of Magnesium Sulfate for Neuroprotection Prior to Preterm Birth Acta Obstetricia Et Gynecologica Scandinavica. Dec, 2023 | Pubmed ID: 37680134 Two Different Isoforms of Osteopontin Modulate Myelination and Axonal Integrity FASEB BioAdvances. Aug, 2023 | Pubmed ID: 37554545 Mechanisms of Tertiary Neurodegeneration After Neonatal Hypoxic-Ischemic Brain Damage Pediatric Medicine (Hong Kong, China). Aug, 2022 | Pubmed ID: 37601279 Microbial and Human Transcriptome in Vaginal Fluid at Midgestation: Association with Spontaneous Preterm Delivery Clinical and Translational Medicine. Sep, 2022 | Pubmed ID: 36103557 Reproductive, Obstetric, and Long-term Health Outcome After Uterus Transplantation: Results of the First Clinical Trial Fertility and Sterility. Sep, 2022 | Pubmed ID: 35697530 Maternal and Fetal Serum Concentrations of Magnesium After Administration of a 6-g Bolus Dose of Magnesium Sulfate (MgSO ) to Women with Imminent Preterm Delivery Acta Obstetricia Et Gynecologica Scandinavica. Aug, 2022 | Pubmed ID: 35501953 Temporal Brain Transcriptome Analysis Reveals Key Pathological Events After Germinal Matrix Hemorrhage in Neonatal Rats Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Sep, 2022 | Pubmed ID: 35491813 Induction of Mitochondrial Fragmentation and Mitophagy After Neonatal Hypoxia-Ischemia Cells. Apr, 2022 | Pubmed ID: 35406757 New Possibilities for Neuroprotection in Neonatal Hypoxic-ischemic Encephalopathy European Journal of Pediatrics. Mar, 2022 | Pubmed ID: 34820702 Induction of Labour at 41 weeks of Gestation Versus Expectant Management and Induction of Labour at 42 weeks of Gestation: A cost-effectiveness Analysis BJOG : an International Journal of Obstetrics and Gynaecology. Dec, 2022 | Pubmed ID: 34534404 C3a Receptor Signaling Inhibits Neurodegeneration Induced by Neonatal Hypoxic-Ischemic Brain Injury Frontiers in Immunology. 2021 | Pubmed ID: 34975856 N-Acetyl Cysteine Restores Sirtuin-6 and Decreases HMGB1 Release Following Lipopolysaccharide-Sensitized Hypoxic-Ischemic Brain Injury in Neonatal Mice Frontiers in Cellular Neuroscience. 2021 | Pubmed ID: 34867200 White Matter Injury but Not Germinal Matrix Hemorrhage Induces Elevated Osteopontin Expression in Human Preterm Brains Acta Neuropathologica Communications. Oct, 2021 | Pubmed ID: 34654477 Function and Biomarkers of the Blood-Brain Barrier in a Neonatal Germinal Matrix Haemorrhage Model Cells. Jul, 2021 | Pubmed ID: 34359845 Single-cell Atlas Reveals Meningeal Leukocyte Heterogeneity in the Developing Mouse Brain Genes & Development. Aug, 2021 | Pubmed ID: 34301765 Therapies for Neonatal Encephalopathy: Targeting the Latent, Secondary and Tertiary Phases of Evolving Brain Injury Seminars in Fetal & Neonatal Medicine. 10, 2021 | Pubmed ID: 34154945 Effect of Second-trimester Sonographic Cervical Length on the Risk of Spontaneous Preterm Delivery in Different Risk Groups: A Prospective Observational Multicenter Study Acta Obstetricia Et Gynecologica Scandinavica. Sep, 2021 | Pubmed ID: 34096036 Efficacy and Safety of Oral Misoprostol Vs Transvaginal Balloon Catheter for Labor Induction: An Observational Study Within the SWEdish Postterm Induction Study (SWEPIS) Acta Obstetricia Et Gynecologica Scandinavica. Aug, 2021 | Pubmed ID: 33768520 Neuroprotection Offered by Mesenchymal Stem Cells in Perinatal Brain Injury: Role of Mitochondria, Inflammation, and Reactive Oxygen Species Journal of Neurochemistry. 07, 2021 | Pubmed ID: 33314066 Induction of Labour at 41 Weeks or Expectant Management Until 42 Weeks: A Systematic Review and an Individual Participant Data Meta-analysis of Randomised Trials PLoS Medicine. Dec, 2020 | Pubmed ID: 33290410 Type 2 Innate Lymphoid Cells Accumulate in the Brain After Hypoxia-Ischemia but Do Not Contribute to the Development of Preterm Brain Injury Frontiers in Cellular Neuroscience. 2020 | Pubmed ID: 32848629 Neuroprotective Effects of Diabetes Drugs for the Treatment of Neonatal Hypoxia-Ischemia Encephalopathy Frontiers in Cellular Neuroscience. 2020 | Pubmed ID: 32435185 Severe Maternal Morbidity and Mortality Associated with COVID-19: The Risk Should Not Be Downplayed Acta Obstetricia Et Gynecologica Scandinavica. Jul, 2020 | Pubmed ID: 32386440 Inhibiting the Interaction Between Apoptosis-inducing Factor and Cyclophilin A Prevents Brain Injury in Neonatal Mice After Hypoxia-ischemia Neuropharmacology. Jul, 2020 | Pubmed ID: 32277944 Overexpression of Apoptosis Inducing Factor Aggravates Hypoxic-ischemic Brain Injury in Neonatal Mice Cell Death & Disease. Jan, 2020 | Pubmed ID: 32001673 N-acetylcysteine Inhibits Bacterial Lipopeptide-mediated Neutrophil Transmigration Through the Choroid Plexus in the Developing Brain Acta Neuropathologica Communications. Jan, 2020 | Pubmed ID: 31973769 Microbial Invasion of the Amniotic Cavity is Associated with Impaired Cognitive and Motor Function at School Age in Preterm Children Pediatric Research. Apr, 2020 | Pubmed ID: 31711067 Post-mortem Characterisation of a Case With an Variant, Agenesis of the Corpus Callosum and Neuronal Heterotopia Frontiers in Physiology. 2019 | Pubmed ID: 31231230 Dysmaturation of Somatostatin Interneurons Following Umbilical Cord Occlusion in Preterm Fetal Sheep Frontiers in Physiology. 2019 | Pubmed ID: 31178744 The Role of Mitochondrial and Endoplasmic Reticulum Reactive Oxygen Species Production in Models of Perinatal Brain Injury Antioxidants & Redox Signaling. Sep, 2019 | Pubmed ID: 30957515 Long-term Risk of Neuropsychiatric Disease After Exposure to Infection In Utero JAMA Psychiatry. Jun, 2019 | Pubmed ID: 30840048 Choroid Plexus Transcriptome and Ultrastructure Analysis Reveals a TLR2-specific Chemotaxis Signature and Cytoskeleton Remodeling in Leukocyte Trafficking Brain, Behavior, and Immunity. Jul, 2019 | Pubmed ID: 30822467 Lipopolysaccharide-induced Alteration of Mitochondrial Morphology Induces a Metabolic Shift in Microglia Modulating the Inflammatory Response in Vitro and in Vivo Glia. Jun, 2019 | Pubmed ID: 30637805 Positive and Negative Conditioning in the Neonatal Brain Conditioning Medicine. Oct, 2018 | Pubmed ID: 31214666 Lack of the Brain-specific Isoform of Apoptosis-inducing Factor Aggravates Cerebral Damage in a Model of Neonatal Hypoxia-ischemia Cell Death & Disease. Dec, 2018 | Pubmed ID: 30584234 Peripheral Myeloid Cells Contribute to Brain Injury in Male Neonatal Mice Journal of Neuroinflammation. Oct, 2018 | Pubmed ID: 30376851 Myelination Induction by a Histamine H3 Receptor Antagonist in a Mouse Model of Preterm White Matter Injury Brain, Behavior, and Immunity. Nov, 2018 | Pubmed ID: 30218783 Neuroprotective Exendin-4 Enhances Hypothermia Therapy in a Model of Hypoxic-ischaemic Encephalopathy Brain : a Journal of Neurology. Oct, 2018 | Pubmed ID: 30165597 Blood-based Cerebral Biomarkers in Preeclampsia: Plasma Concentrations of NfL, Tau, S100B and NSE During Pregnancy in Women Who Later Develop Preeclampsia - A Nested Case Control Study PloS One. 2018 | Pubmed ID: 29719006 TWEAK Receptor Deficiency Has Opposite Effects on Female and Male Mice Subjected to Neonatal Hypoxia-Ischemia Frontiers in Neurology. 2018 | Pubmed ID: 29706927 Lymphocytes Contribute to the Pathophysiology of Neonatal Brain Injury Frontiers in Neurology. 2018 | Pubmed ID: 29615958 Mitochondrial Dynamics, Mitophagy and Biogenesis in Neonatal Hypoxic-ischaemic Brain Injury FEBS Letters. Mar, 2018 | Pubmed ID: 29265370 γδ T Cells Contribute to Injury in the Developing Brain The American Journal of Pathology. Mar, 2018 | Pubmed ID: 29248460 Increase of Neuronal Injury Markers Tau and Neurofilament Light Proteins in Umbilical Blood After Intrapartum Asphyxia The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. Sep, 2018 | Pubmed ID: 28629249 γδT Cells but Not αβT Cells Contribute to Sepsis-induced White Matter Injury and Motor Abnormalities in Mice Journal of Neuroinflammation. Dec, 2017 | Pubmed ID: 29262837 Oxidative Stress and Endoplasmic Reticulum (ER) Stress in the Development of Neonatal Hypoxic-ischaemic Brain Injury Biochemical Society Transactions. Oct, 2017 | Pubmed ID: 28939695 Cell Death in the Developing Brain After Hypoxia-Ischemia Frontiers in Cellular Neuroscience. 2017 | Pubmed ID: 28878624 Chorioamnionitis in the Development of Cerebral Palsy: A Meta-analysis and Systematic Review Pediatrics. Jun, 2017 | Pubmed ID: 28814548 Mitochondria, Bioenergetics and Excitotoxicity: New Therapeutic Targets in Perinatal Brain Injury Frontiers in Cellular Neuroscience. 2017 | Pubmed ID: 28747873 Implicating Receptor Activator of NF-κB (RANK)/RANK Ligand Signalling in Microglial Responses to Toll-Like Receptor Stimuli Developmental Neuroscience. 2017 | Pubmed ID: 28402971 Systemic Activation of Toll-like Receptor 2 Suppresses Mitochondrial Respiration and Exacerbates Hypoxic-ischemic Injury in the Developing Brain Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Apr, 2017 | Pubmed ID: 28139935 Effect of Trp53 Gene Deficiency on Brain Injury After Neonatal Hypoxia-ischemia Oncotarget. Feb, 2017 | Pubmed ID: 28076846 Intranasal C3a Treatment Ameliorates Cognitive Impairment in a Mouse Model of Neonatal Hypoxic-ischemic Brain Injury Experimental Neurology. Apr, 2017 | Pubmed ID: 28062175 Immune Responses in Perinatal Brain Injury Brain, Behavior, and Immunity. Jul, 2017 | Pubmed ID: 27865947 TLR2-mediated Leukocyte Trafficking to the Developing Brain Journal of Leukocyte Biology. Jan, 2017 | Pubmed ID: 27493242 Temporal Characterization of Microglia/Macrophage Phenotypes in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury Frontiers in Cellular Neuroscience. 2016 | Pubmed ID: 28018179 Modeling Hormonal and Inflammatory Contributions to Preterm and Term Labor Using Uterine Temporal Transcriptomics BMC Medicine. Jun, 2016 | Pubmed ID: 27291689 One Uterus Bridging Three Generations: First Live Birth After Mother-to-daughter Uterus Transplantation Fertility and Sterility. Aug, 2016 | Pubmed ID: 27125227 Heme Oxygenase-1 Mediates Neuroprotection Conferred by Argon in Combination with Hypothermia in Neonatal Hypoxia-Ischemia Brain Injury Anesthesiology. Jul, 2016 | Pubmed ID: 27065095 Perinatal Brain Damage: The Term Infant Neurobiology of Disease. Aug, 2016 | Pubmed ID: 26409031 Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury International Journal of Molecular Sciences. Sep, 2015 | Pubmed ID: 26393574 Specific Lipopolysaccharide Serotypes Induce Differential Maternal and Neonatal Inflammatory Responses in a Murine Model of Preterm Labor The American Journal of Pathology. Sep, 2015 | Pubmed ID: 26212908 Staphylococcus Epidermidis Bacteremia Induces Brain Injury in Neonatal Mice Via Toll-like Receptor 2-Dependent and -Independent Pathways The Journal of Infectious Diseases. Nov, 2015 | Pubmed ID: 25883383 Does Caspase-6 Have a Role in Perinatal Brain Injury? Developmental Neuroscience. 2015 | Pubmed ID: 25823427 Transvaginal Sonographic Evaluation of Cervical Length in the Second Trimester of Asymptomatic Singleton Pregnancies, and the Risk of Preterm Delivery Acta Obstetricia Et Gynecologica Scandinavica. Jun, 2015 | Pubmed ID: 25732204 The Role of Inflammation in Perinatal Brain Injury Nature Reviews. Neurology. Apr, 2015 | Pubmed ID: 25686754 Brain Barrier Properties and Cerebral Blood Flow in Neonatal Mice Exposed to Cerebral Hypoxia-ischemia Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. May, 2015 | Pubmed ID: 25627141 Livebirth After Uterus Transplantation Lancet (London, England). Feb, 2015 | Pubmed ID: 25301505 The Effect of Osteopontin and Osteopontin-derived Peptides on Preterm Brain Injury Journal of Neuroinflammation. Dec, 2014 | Pubmed ID: 25465048 The Immune Response After Hypoxia-ischemia in a Mouse Model of Preterm Brain Injury Journal of Neuroinflammation. Sep, 2014 | Pubmed ID: 25187205 Targeting the Vasculature for Cerebroprotection in the Immature Brain Experimental Neurology. Nov, 2014 | Pubmed ID: 25118621 Microglia Toxicity in Preterm Brain Injury Reproductive Toxicology (Elmsford, N.Y.). Sep, 2014 | Pubmed ID: 24768662 Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Signaling and Cell Death in the Immature Central Nervous System After Hypoxia-ischemia and Inflammation The Journal of Biological Chemistry. Mar, 2014 | Pubmed ID: 24509861 Innate Defense Regulator Peptide 1018 Protects Against Perinatal Brain Injury Annals of Neurology. Mar, 2014 | Pubmed ID: 24339166 Receptor for Complement Peptide C3a: a Therapeutic Target for Neonatal Hypoxic-ischemic Brain Injury FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2013 | Pubmed ID: 23737250 Time-dependent Effects of Systemic Lipopolysaccharide Injection on Regulators of Antioxidant Defence Nrf2 and PGC-1α in the Neonatal Rat Brain Neuroimmunomodulation. 2013 | Pubmed ID: 23635713 Characterization of Phenotype Markers and Neuronotoxic Potential of Polarised Primary Microglia in Vitro Brain, Behavior, and Immunity. Aug, 2013 | Pubmed ID: 23454862 Molecular Mechanisms of Neonatal Brain Injury Neurology Research International. 2012 | Pubmed ID: 22363841 Inflammation During Fetal and Neonatal Life: Implications for Neurologic and Neuropsychiatric Disease in Children and Adults Annals of Neurology. Apr, 2012 | Pubmed ID: 22334391 Combined Effect of Hypothermia and Caspase-2 Gene Deficiency on Neonatal Hypoxic-ischemic Brain Injury Pediatric Research. May, 2012 | Pubmed ID: 22322383 Inflammatory-induced Hibernation in the Fetus: Priming of Fetal Sheep Metabolism Correlates with Developmental Brain Injury PloS One. 2011 | Pubmed ID: 22242129 Delayed Cortical Impairment Following Lipopolysaccharide Exposure in Preterm Fetal Sheep Annals of Neurology. Nov, 2011 | Pubmed ID: 22002627 Isolation Des Mitochondries De Cerveau De Souris Néonatales Journal of Neurochemistry. Dec, 2011 | Pubmed ID: 21985402 Trace Fear Conditioning Detects Hypoxic-ischemic Brain Injury in Neonatal Mice Developmental Neuroscience. 2011 | Pubmed ID: 21778703 Safety Aspects of Administration Longitudinale Du Complexe D'IGF-I/IGFBP-3 Chez Les Souris Néonatales Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Aug, 2011 | Pubmed ID: 21696987 Genetic Inhibition of Caspase-2 Reduces Hypoxic-ischemic and Excitotoxic Neonatal Brain Injury Annals of Neurology. Nov, 2011 | Pubmed ID: 21674587 Systemic Stimulation of TLR2 Impairs Neonatal Mouse Brain Development PloS One. May, 2011 | Pubmed ID: 21573120 Effet Neuroprotecteur Du Peptide Inhibiteur De Bax Sur La Lésion Cérébrale Néonatale Stroke; a Journal of Cerebral Circulation. Sep, 2010 | Pubmed ID: 20671246 Attenuation of Reactive Gliosis Does Not Affect Infarct Volume in Neonatal Hypoxic-ischemic Brain Injury in Mice PloS One. Apr, 2010 | Pubmed ID: 20442854 Galectin-3 Contributes to Neonatal Hypoxic-ischemic Brain Injury Neurobiology of Disease. Apr, 2010 | Pubmed ID: 20053377 Nuclear Translocation and Calpain-dependent Reduction of Bcl-2 After Neonatal Cerebral Hypoxia-ischemia Brain, Behavior, and Immunity. Jul, 2010 | Pubmed ID: 19782128 The Role of Toll-like Receptors in Perinatal Brain Injury Clinics in Perinatology. Dec, 2009 | Pubmed ID: 19944834 Lipopolysaccharide Sensitizes Neonatal Hypoxic-ischemic Brain Injury in a MyD88-dependent Manner Journal of Immunology (Baltimore, Md. : 1950). Dec, 2009 | Pubmed ID: 19917690 White Matter Damage After Chronic Subclinical Inflammation in Newborn Mice Journal of Child Neurology. Sep, 2009 | Pubmed ID: 19745089 Developmental Shift of Cyclophilin D Contribution to Hypoxic-ischemic Brain Injury The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2009 | Pubmed ID: 19244535 Brain Injury in Preterm Infants--what Can the Obstetrician Do? Early Human Development. Mar, 2005 | Pubmed ID: 15814204 Effect of Inflammation on Central Nervous System Development and Vulnerability Current Opinion in Neurology. Apr, 2005 | Pubmed ID: 15791140 Preconditioning and the Developing Brain Seminars in Perinatology. Dec, 2004 | Pubmed ID: 15693395 [A New Monitoring Method for Safer Child Delivery. Lower Number of Metabolic Acidosis Cases with Fetal ECG and Cardiotocography] Lakartidningen. Nov, 2004 | Pubmed ID: 15631221 [Chorioamnionitis--risk Factor of Cerebral Palsy in Fullterm Infants] Lakartidningen. Aug, 2004 | Pubmed ID: 15446690 Mitochondrial Impairment in the Developing Brain After Hypoxia-ischemia Journal of Bioenergetics and Biomembranes. Aug, 2004 | Pubmed ID: 15377874 PARP-1 Gene Disruption in Mice Preferentially Protects Males from Perinatal Brain Injury Journal of Neurochemistry. Sep, 2004 | Pubmed ID: 15312162 No Correlation Between Cerebral Palsy and Cytokines in Postnatal Blood of Preterms Pediatric Research. Apr, 2003 | Pubmed ID: 12612191 [Increased Mortality Among Infants Born at Night. A Reflection of Inadequate Perinatal Intensive Care Resources in the Night-time?] Lakartidningen. May, 2002 | Pubmed ID: 12082926 Sequelae of Chorioamnionitis Current Opinion in Infectious Diseases. Jun, 2002 | Pubmed ID: 12015466 Models of White Matter Injury: Comparison of Infectious, Hypoxic-ischemic, and Excitotoxic Insults Mental Retardation and Developmental Disabilities Research Reviews. 2002 | Pubmed ID: 11921384 Antenatal Brain Injury: Aetiology and Possibilities of Prevention Seminars in Neonatology : SN. Feb, 2000 | Pubmed ID: 10802749 [Spontaneous Premature Birth: Physiopathology, Predictors and Management. The Frequency is Constant--early Detection Can Improve Therapeutic Possibilities] Lakartidningen. Jan, 2000 | Pubmed ID: 10684223 Un modèle d’injection veineuse rétroorbitaire chez un rongeur néonatal Eridan Rocha-Ferreira1, Syam Nair1, Owen Herrock1, Erik Axel Andersson2, Carl Joakim Ek2, Carina Mallard2, Henrik Hagberg1 1Centre of Perinatal Medicine and Health, Institute of Clinical Sciences, Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, 2Centre of Perinatal Medicine and Health, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg JoVE 65386 Neuroscience
Un modèle d’injection veineuse rétroorbitaire chez un rongeur néonatal Eridan Rocha-Ferreira1, Syam Nair1, Owen Herrock1, Erik Axel Andersson2, Carl Joakim Ek2, Carina Mallard2, Henrik Hagberg1 1Centre of Perinatal Medicine and Health, Institute of Clinical Sciences, Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, 2Centre of Perinatal Medicine and Health, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg JoVE 65386 Neuroscience