Hideki Hasegawa Department of Pathology National Institute of Infectious Diseases Biography Publications Institution JoVE Articles Hideki Hasegawa has not added a biography. If you are Hideki Hasegawa and would like to personalize this page please email our Author Liaison for assistance. Publications Transient Appearance of Plasmablasts in the Peripheral Blood of Japanese Patients with Severe Fever with Thrombocytopenia Syndrome The Journal of Infectious Diseases. Feb, 2019 | Pubmed ID: 30721983 Unusual Manifestation of Disseminated Herpes Simplex Virus Type 2 Infection Associated with Pharyngotonsilitis, Esophagitis, and Hemophagocytic Lymphohisitocytosis Without Genital Involvement BMC Infectious Diseases. Jan, 2019 | Pubmed ID: 30654754 TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models After Coronavirus Infection Journal of Virology. Mar, 2019 | Pubmed ID: 30626688 Acute Respiratory Infection in Human Dipeptidyl Peptidase 4-Transgenic Mice Infected with Middle East Respiratory Syndrome Coronavirus Journal of Virology. Mar, 2019 | Pubmed ID: 30626685 IgA Tetramerization Improves Target Breadth but Not Peak Potency of Functionality of Anti-influenza Virus Broadly Neutralizing Antibody PLoS Pathogens. 01, 2019 | Pubmed ID: 30605488 Mouse LIMR3/CD300f is a Negative Regulator of the Antimicrobial Activity of Neutrophils Scientific Reports. Nov, 2018 | Pubmed ID: 30479367 Intranasal Inactivated Influenza Vaccines for the Prevention of Seasonal Influenza Epidemics Expert Review of Vaccines. 08, 2018 | Pubmed ID: 30092690 The Marmoset As an Animal Model of Influenza: Infection With A(H1N1)pdm09 and Highly Pathogenic A(H5N1) Viruses Via the Conventional or Tracheal Spray Route Frontiers in Microbiology. 2018 | Pubmed ID: 29867791 A Sialylated Voltage-Dependent Ca Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells Cell Host & Microbe. 06, 2018 | Pubmed ID: 29779930 Application of HTLV-1 Tax Transgenic Mice for Therapeutic Intervention Advances in Biological Regulation. May, 2018 | Pubmed ID: 29588208 Experimental Infection of Cynomolgus Macaques with Highly Pathogenic H5N1 Influenza Virus Through the Aerosol Route Scientific Reports. Mar, 2018 | Pubmed ID: 29556081 IgA Polymerization Contributes to Efficient Virus Neutralization on Human Upper Respiratory Mucosa After Intranasal Inactivated Influenza Vaccine Administration Human Vaccines & Immunotherapeutics. 06, 2018 | Pubmed ID: 29425074 2017 International Meeting of the Global Virus Network Antiviral Research. 05, 2018 | Pubmed ID: 29421321 Neutralizing Antibodies Induced by Gene-Based Hydrodynamic Injection Have a Therapeutic Effect in Lethal Influenza Infection Frontiers in Immunology. 2018 | Pubmed ID: 29416543 Characterization of a Feline Influenza A(H7N2) Virus Emerging Infectious Diseases. 01, 2018 | Pubmed ID: 29260686 Syrian Hamster As an Animal Model for the Study of Human Influenza Virus Infection Journal of Virology. 02, 2018 | Pubmed ID: 29212926 Combination Therapy With Neuraminidase and Polymerase Inhibitors in Nude Mice Infected With Influenza Virus The Journal of Infectious Diseases. Mar, 2018 | Pubmed ID: 29186472 A Patient with Severe Fever with Thrombocytopenia Syndrome and Hemophagocytic Lymphohistiocytosis-associated Involvement of the Central Nervous System Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy. Apr, 2018 | Pubmed ID: 29138019 Mechanism of Action of the Anti-Influenza Virus Active Kampo (Traditional Japanese Herbal) Medicine, Hochuekkito Pharmacology. Dec, 2017 | Pubmed ID: 29275416 CGAMP Promotes Germinal Center Formation and Production of IgA in Nasal-Associated Lymphoid Tissue Medical Sciences (Basel, Switzerland). Dec, 2017 | Pubmed ID: 29258267 Alleviation of Lipopolysaccharide/d-galactosamine-induced Liver Injury in Leukocyte Cell-derived Chemotaxin 2 Deficient Mice Biochemistry and Biophysics Reports. Dec, 2017 | Pubmed ID: 29090278 Induction of Lung CD8 T Cell Responses by Consecutive Inoculations of a Poly(I:C) Influenza Vaccine Vaccine. 12, 2017 | Pubmed ID: 29079103 A Highly Pathogenic Avian H7N9 Influenza Virus Isolated from A Human Is Lethal in Some Ferrets Infected Via Respiratory Droplets Cell Host & Microbe. Nov, 2017 | Pubmed ID: 29056430 Emergence of Oseltamivir-Resistant H7N9 Influenza Viruses in Immunosuppressed Cynomolgus Macaques The Journal of Infectious Diseases. 09, 2017 | Pubmed ID: 28931216 The Road to a More Effective Influenza Vaccine: Up to Date Studies and Future Prospects Vaccine. 09, 2017 | Pubmed ID: 28866292 Interleukin-6-dependent Growth in a Newly Established Plasmablastic Lymphoma Cell Line and Its Therapeutic Targets Scientific Reports. Aug, 2017 | Pubmed ID: 28860565 Pulmonary Inflammation and Cytokine Dynamics of Bronchoalveolar Lavage Fluid from a Mouse Model of Bronchial Asthma During A(H1N1)pdm09 Influenza Infection Scientific Reports. 08, 2017 | Pubmed ID: 28831046 Functional and Structural Characteristics of Secretory IgA Antibodies Elicited by Mucosal Vaccines Against Influenza Virus Vaccine. 09, 2017 | Pubmed ID: 28780981 Conserved Sequences of BART and BHRF Regions Encoding Viral MicroRNAs in Epstein-Barr Virus-associated Lymphoma BMC Research Notes. Jul, 2017 | Pubmed ID: 28705173 Intranasal Administration of Whole Inactivated Influenza Virus Vaccine As a Promising Influenza Vaccine Candidate Viral Immunology. Jul/Aug, 2017 | Pubmed ID: 28650274 2016 International Meeting of the Global Virus Network Antiviral Research. 06, 2017 | Pubmed ID: 28315708 Impacts of Allergic Airway Inflammation on Lung Pathology in a Mouse Model of Influenza A Virus Infection PloS One. 2017 | Pubmed ID: 28245238 Next-generation Sequencing of MiRNAs in Clinical Samples of Epstein-Barr Virus-associated B-cell Lymphomas Cancer Medicine. 03, 2017 | Pubmed ID: 28181423 Unusual Presentation of a Severely Ill Patient Having Severe Fever with Thrombocytopenia Syndrome: a Case Report Journal of Medical Case Reports. Feb, 2017 | Pubmed ID: 28153057 A Single Vaccination of Nonhuman Primates with Highly Attenuated Smallpox Vaccine, LC16m8, Provides Long-term Protection Against Monkeypox Japanese Journal of Infectious Diseases. Jul, 2017 | Pubmed ID: 28003603 The Microminipig As an Animal Model for Influenza A Virus Infection Journal of Virology. Jan, 2017 | Pubmed ID: 27807225 Deep-Sequence Identification and Role in Virus Replication of a JC Virus Quasispecies in Patients with Progressive Multifocal Leukoencephalopathy Journal of Virology. Jan, 2017 | Pubmed ID: 27795410 Histopathological Findings of Lung with A/H1N1pdm09 Infection-Associated Acute Respiratory Distress Syndrome in the Post-Pandemic Season Japanese Journal of Infectious Diseases. Mar, 2017 | Pubmed ID: 27357984 Screening Transplant Donors for HTLV-1 and -2 Blood. 12, 2016 | Pubmed ID: 28034870 Reducing the Global Burden of HTLV-1 Infection: An Agenda for Research and Action Antiviral Research. Nov, 2016 | Pubmed ID: 27840202 Protective Neutralizing Influenza Antibody Response in the Absence of T Follicular Helper Cells Nature Immunology. Dec, 2016 | Pubmed ID: 27798619 Profile of Exosomal and Intracellular MicroRNA in Gamma-Herpesvirus-Infected Lymphoma Cell Lines PloS One. 2016 | Pubmed ID: 27611973 Intracerebral Inoculation of Mouse-passaged Saffold Virus Type 3 Affects Cerebellar Development in Neonatal Mice Journal of Virology. Aug, 2016 | Pubmed ID: 27581974 Establishing and Characterizing a New Primary Effusion Lymphoma Cell Line Harboring Kaposi's Sarcoma-associated Herpesvirus Infectious Agents and Cancer. 2016 | Pubmed ID: 27536332 Fungus-Derived Neoechinulin B As a Novel Antagonist of Liver X Receptor, Identified by Chemical Genetics Using a Hepatitis C Virus Cell Culture System Journal of Virology. 10, 2016 | Pubmed ID: 27489280 Assessment of Outer Membrane Vesicles of Periodontopathic Bacterium Porphyromonas Gingivalis As Possible Mucosal Immunogen Vaccine. 08, 2016 | Pubmed ID: 27461458 Association of Lymph-node Antigens with Lower Gag-specific Central-memory and Higher Env-specific Effector-memory CD8(+) T-cell Frequencies in a Macaque AIDS Model Scientific Reports. 07, 2016 | Pubmed ID: 27452272 TMPRSS2 Independency for Haemagglutinin Cleavage In Vivo Differentiates Influenza B Virus from Influenza A Virus Scientific Reports. 07, 2016 | Pubmed ID: 27389476 Efficacy of T-705 (Favipiravir) in the Treatment of Infections with Lethal Severe Fever with Thrombocytopenia Syndrome Virus MSphere. Jan-Feb, 2016 | Pubmed ID: 27303697 Intranasal Inactivated Influenza Vaccines: a Reasonable Approach to Improve the Efficacy of Influenza Vaccine? Japanese Journal of Infectious Diseases. 2016 | Pubmed ID: 27212584 Evaluation of Vero-cell-derived Simian Endogenous Retrovirus Infection in Humans by Detection of Viral Genome in Clinicopathological Samples and Commercialized Vaccines and by Serology of Japanese General Population Vaccine. 05, 2016 | Pubmed ID: 27113161 Severe Fever with Thrombocytopenia Syndrome Virus Antigen Detection Using Monoclonal Antibodies to the Nucleocapsid Protein PLoS Neglected Tropical Diseases. Apr, 2016 | Pubmed ID: 27045364 Non Susceptibility of Neonatal and Adult Rats Against the Middle East Respiratory Syndrome Coronavirus Japanese Journal of Infectious Diseases. Nov, 2016 | Pubmed ID: 27000459 Arenavirus Diversity and Phylogeography of Mastomys Natalensis Rodents, Nigeria Emerging Infectious Diseases. Apr, 2016 | Pubmed ID: 26982388 Adenovirus Type 7 Pneumonia in Children Who Died from Measles-Associated Pneumonia, Hanoi, Vietnam, 2014 Emerging Infectious Diseases. Apr, 2016 | Pubmed ID: 26926035 The RNA- and TRIM25-Binding Domains of Influenza Virus NS1 Protein Are Essential for Suppression of NLRP3 Inflammasome-Mediated Interleukin-1β Secretion Journal of Virology. Apr, 2016 | Pubmed ID: 26865721 Neuropathogenicity of Two Saffold Virus Type 3 Isolates in Mouse Models PloS One. 2016 | Pubmed ID: 26828718 The Effect of Mucoadhesive Excipient on the Nasal Retention Time of and the Antibody Responses Induced by an Intranasal Influenza Vaccine Vaccine. Feb, 2016 | Pubmed ID: 26802605 Development of a New Real-time PCR System for Simultaneous Detection of Bacteria and Fungi in Pathological Samples International Journal of Clinical and Experimental Pathology. 2015 | Pubmed ID: 26823918 Protective Antibody Responses Against A(H1N1)pdm09 Primed by Infection and Recalled by Intranasal Vaccination Vaccine. Nov, 2015 | Pubmed ID: 26432916 Fumagillin, a Potent Angiogenesis Inhibitor, Induces Kaposi Sarcoma-associated Herpesvirus Replication in Primary Effusion Lymphoma Cells Biochemical and Biophysical Research Communications. Aug, 2015 | Pubmed ID: 26093300 Host Adaptation and the Alteration of Viral Properties of the First Influenza A/H1N1pdm09 Virus Isolated in Japan PloS One. 2015 | Pubmed ID: 26079133 Relationship of the Quaternary Structure of Human Secretory IgA to Neutralization of Influenza Virus Proceedings of the National Academy of Sciences of the United States of America. Jun, 2015 | Pubmed ID: 26056267 Seroprevalence of Trichodysplasia Spinulosa-associated Polyomavirus in Japan Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology. Apr, 2015 | Pubmed ID: 25766994 A Mutant H3N2 Influenza Virus Uses an Alternative Activation Mechanism in TMPRSS2 Knockout Mice by Loss of an Oligosaccharide in the Hemagglutinin Stalk Region Journal of Virology. May, 2015 | Pubmed ID: 25673722 The Pathogenesis of 3 Neurotropic Flaviviruses in a Mouse Model Depends on the Route of Neuroinvasion After Viremia Journal of Neuropathology and Experimental Neurology. Mar, 2015 | Pubmed ID: 25668565 Establishment of a Panel of In-house Polyclonal Antibodies for the Diagnosis of Enterovirus Infections Neuropathology : Official Journal of the Japanese Society of Neuropathology. Apr, 2015 | Pubmed ID: 25263613 Mucosal Immunization and Adjuvants Current Topics in Microbiology and Immunology. 2015 | Pubmed ID: 25015787 Evidence for Human Herpesvirus-6B Infection of Regulatory T-cells in Acute Systemic Lymphadenitis in an Immunocompetent Adult with the Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome: a Case Report Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology. Nov, 2014 | Pubmed ID: 25249343 Detection of Trichodysplasia Spinulosa-associated Polyomavirus in a Fatal Case of Myocarditis in a Seven-month-old Girl International Journal of Clinical and Experimental Pathology. 2014 | Pubmed ID: 25197415 Pathogenesis of Fulminant Monkeypox with Bacterial Sepsis After Experimental Infection with West African Monkeypox Virus in a Cynomolgus Monkey International Journal of Clinical and Experimental Pathology. 2014 | Pubmed ID: 25120821 Preclinical Efficacy of the Synthetic Retinoid ST1926 for Treating Adult T-cell Leukemia/lymphoma Blood. Sep, 2014 | Pubmed ID: 25035162 Cytokine Profile of Bronchoalveolar Lavage Fluid from a Mouse Model of Bronchial Asthma During Seasonal H1N1 Infection Cytokine. Oct, 2014 | Pubmed ID: 24998935 Circulating Avian Influenza Viruses Closely Related to the 1918 Virus Have Pandemic Potential Cell Host & Microbe. Jun, 2014 | Pubmed ID: 24922572 Combatting Infectious Diseases; Nanotechnology As a Platform for Rational Vaccine Design Advanced Drug Delivery Reviews. Jul, 2014 | Pubmed ID: 24862579 Effects of Toll-like Receptor Stimulation on Eosinophilic Infiltration in Lungs of BALB/c Mice Immunized with UV-inactivated Severe Acute Respiratory Syndrome-related Coronavirus Vaccine Journal of Virology. Aug, 2014 | Pubmed ID: 24850731 The Prevalence of Opportunistic Infections and Malignancies in Autopsied Patients with Human Immunodeficiency Virus Infection in Japan BMC Infectious Diseases. Apr, 2014 | Pubmed ID: 24775713 Neutrophil Depletion Suppresses Pulmonary Vascular Hyperpermeability and Occurrence of Pulmonary Edema Caused by Hantavirus Infection in C.B-17 SCID Mice Journal of Virology. Jul, 2014 | Pubmed ID: 24719427 The Host Protease TMPRSS2 Plays a Major Role in in Vivo Replication of Emerging H7N9 and Seasonal Influenza Viruses Journal of Virology. May, 2014 | Pubmed ID: 24600012 Classification of AIDS-related Lymphoma Cases Between 1987 and 2012 in Japan Based on the WHO Classification of Lymphomas, Fourth Edition Cancer Medicine. Feb, 2014 | Pubmed ID: 24407967 Viroporin Activity of the JC Polyomavirus is Regulated by Interactions with the Adaptor Protein Complex 3 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2013 | Pubmed ID: 24167297 Excessive Cytokine Response to Rapid Proliferation of Highly Pathogenic Avian Influenza Viruses Leads to Fatal Systemic Capillary Leakage in Chickens PloS One. 2013 | Pubmed ID: 23874602 Characterization of H7N9 Influenza A Viruses Isolated from Humans Nature. Sep, 2013 | Pubmed ID: 23842494 Canine Distemper Virus Associated with a Lethal Outbreak in Monkeys Can Readily Adapt to Use Human Receptors Journal of Virology. Jun, 2013 | Pubmed ID: 23596291 Evaluation of the Effectiveness and Safety of Chitosan Derivatives As Adjuvants for Intranasal Vaccines Viral Immunology. Apr, 2013 | Pubmed ID: 23509985 Frequent Detection of Merkel Cell Polyomavirus DNA in Sera of HIV-1-positive Patients Virology Journal. Mar, 2013 | Pubmed ID: 23496956 Pathological Study of Archival Lung Tissues from Five Fatal Cases of Avian H5N1 Influenza in Vietnam Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Mar, 2013 | Pubmed ID: 23174938 Lethal Canine Distemper Virus Outbreak in Cynomolgus Monkeys in Japan in 2008 Journal of Virology. Jan, 2013 | Pubmed ID: 23135729 Pathogenic Characterization of a Cervical Lymph Node Derived from a Patient with Kawasaki Disease International Journal of Clinical and Experimental Pathology. 2012 | Pubmed ID: 23071864 Identification of a Varicella-zoster Virus Replication Inhibitor That Blocks Capsid Assembly by Interacting with the Floor Domain of the Major Capsid Protein Journal of Virology. Nov, 2012 | Pubmed ID: 22933294 Mucosal IgA Responses in Influenza Virus Infections; Thoughts for Vaccine Design Vaccine. Aug, 2012 | Pubmed ID: 22835738 Association of Major Histocompatibility Complex Class I Haplotypes with Disease Progression After Simian Immunodeficiency Virus Challenge in Burmese Rhesus Macaques Journal of Virology. Jun, 2012 | Pubmed ID: 22491464 Herpes Simplex Virus 1 VP22 Regulates Translocation of Multiple Viral and Cellular Proteins and Promotes Neurovirulence Journal of Virology. May, 2012 | Pubmed ID: 22357273 Characterization of Neutralizing Antibodies in Adults After Intranasal Vaccination with an Inactivated Influenza Vaccine Journal of Medical Virology. Feb, 2012 | Pubmed ID: 22170556 Histopathological and Immunohistochemical Findings of 20 Autopsy Cases with 2009 H1N1 Virus Infection Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Jan, 2012 | Pubmed ID: 21874012 Outer Membrane Vesicles of Porphyromonas Gingivalis Elicit a Mucosal Immune Response PloS One. 2011 | Pubmed ID: 22022548 A Novel Function of the N-terminal Domain of PA in Assembly of Influenza A Virus RNA Polymerase Biochemical and Biophysical Research Communications. Nov, 2011 | Pubmed ID: 22001919 Pathology of Kaposi's Sarcoma-Associated Herpesvirus Infection Frontiers in Microbiology. 2011 | Pubmed ID: 21904536 Mobile and Accurate Detection System for Infection by the 2009 Pandemic Influenza A (H1N1) Virus with a Pocket-warmer Reverse-transcriptase Loop-mediated Isothermal Amplification Journal of Medical Virology. Apr, 2011 | Pubmed ID: 21328369 Cross-protective Immunity Against Influenza Virus Infections Induced by Intranasal Vaccination Together with a TLR3-mucosal Adjuvant Human Vaccines. Jan-Feb, 2011 | Pubmed ID: 21321485 Identification and Molecular Characterization of a New Nonsegmented Double-stranded RNA Virus Isolated from Culex Mosquitoes in Japan Virus Research. Jan, 2011 | Pubmed ID: 20875466 Therapy-induced Selective Loss of Leukemia-initiating Activity in Murine Adult T Cell Leukemia The Journal of Experimental Medicine. Dec, 2010 | Pubmed ID: 21135137 Intranasal Administration of Adjuvant-combined Vaccine Protects Monkeys from Challenge with the Highly Pathogenic Influenza A H5N1 Virus Journal of Medical Virology. Oct, 2010 | Pubmed ID: 20827774 Characterization of Quasispecies of Pandemic 2009 Influenza A Virus (A/H1N1/2009) by De Novo Sequencing Using a Next-generation DNA Sequencer PloS One. Apr, 2010 | Pubmed ID: 20428231 Highly Frequent Mutations in Negative Regulators of Multiple Virulence Genes in Group A Streptococcal Toxic Shock Syndrome Isolates PLoS Pathogens. Apr, 2010 | Pubmed ID: 20368967 An Outbreak of Histoplasmosis Among Healthy Young Japanese Women After Traveling to Southeast Asia Internal Medicine (Tokyo, Japan). 2010 | Pubmed ID: 20190491 The First Autopsy Case of Pandemic Influenza (A/H1N1pdm) Virus Infection in Japan: Detection of a High Copy Number of the Virus in Type II Alveolar Epithelial Cells by Pathological and Virological Examination Japanese Journal of Infectious Diseases. Jan, 2010 | Pubmed ID: 20093768 Estimation of the Effective Doses of Nasal-inactivated Influenza Vaccine in Humans from Mouse-model Experiments Japanese Journal of Infectious Diseases. Jan, 2010 | Pubmed ID: 20093755 Induction of Cross-protective Immunity Against Influenza A Virus H5N1 by an Intranasal Vaccine with Extracts of Mushroom Mycelia Journal of Medical Virology. Jan, 2010 | Pubmed ID: 19950232 Covalent Bonded Gag Multimers in Human Immunodeficiency Virus Type-1 Particles Microbiology and Immunology. Nov, 2009 | Pubmed ID: 19903261 PolyI:polyC12U Adjuvant-combined Intranasal Vaccine Protects Mice Against Highly Pathogenic H5N1 Influenza Virus Variants Vaccine. Oct, 2009 | Pubmed ID: 19840660 Effects of the Number of Amino Acid Residues in the Signal Segment Upstream or Downstream of the NS2B-3 Cleavage Site on Production and Secretion of PrM/M-E Virus-like Particles of West Nile Virus Microbes and Infection. Nov, 2009 | Pubmed ID: 19647801 Rabies Virus Dissemination in Neural Tissues of Autopsy Cases Due to Rabies Imported into Japan from the Philippines: Immunohistochemistry Pathology International. Aug, 2009 | Pubmed ID: 19627539 Identification of Cancer Stem Cells in a Tax-transgenic (Tax-Tg) Mouse Model of Adult T-cell Leukemia/lymphoma Blood. Sep, 2009 | Pubmed ID: 19584402 Virulence and Pathophysiology of the Congo Basin and West African Strains of Monkeypox Virus in Non-human Primates The Journal of General Virology. Sep, 2009 | Pubmed ID: 19474247 Development of Mucosal Adjuvants for Intranasal Vaccine for H5N1 Influenza Viruses Therapeutics and Clinical Risk Management. Feb, 2009 | Pubmed ID: 19436601 Protective Immunity Afforded by Inactivated H5N1 (NIBRG-14) Vaccine Requires Antibodies Against Both Hemagglutinin and Neuraminidase in Mice The Journal of Infectious Diseases. Jun, 2009 | Pubmed ID: 19385735 Loop-mediated Isothermal Amplification-based Diagnostic Assay for Monkeypox Virus Infections Journal of Medical Virology. Jun, 2009 | Pubmed ID: 19382264 Comparison of Acellular Pertussis-based Combination Vaccines by Japanese Control Tests for Toxicities and Laboratory Models for Local Reaction Vaccine. Mar, 2009 | Pubmed ID: 19368767 Neutralizing Antibody Against Severe Acute Respiratory Syndrome (SARS)-coronavirus Spike is Highly Effective for the Protection of Mice in the Murine SARS Model Microbiology and Immunology. Feb, 2009 | Pubmed ID: 19291090 Monoclonal Antibody and SiRNAs for Topoisomerase I Suppress Telomerase Activity Hybridoma (2005). Feb, 2009 | Pubmed ID: 19132895 Innate Sensors of Influenza Virus: Clues to Developing Better Intranasal Vaccines Expert Review of Vaccines. Nov, 2008 | Pubmed ID: 18980544 Mouse-passaged Severe Acute Respiratory Syndrome-associated Coronavirus Leads to Lethal Pulmonary Edema and Diffuse Alveolar Damage in Adult but Not Young Mice The American Journal of Pathology. Jun, 2008 | Pubmed ID: 18467696 Diagnosis and Assessment of Monkeypox Virus (MPXV) Infection by Quantitative PCR Assay: Differentiation of Congo Basin and West African MPXV Strains Japanese Journal of Infectious Diseases. Mar, 2008 | Pubmed ID: 18362406 Pathology and Virus Dispersion in Cynomolgus Monkeys Experimentally Infected with Severe Acute Respiratory Syndrome Coronavirus Via Different Inoculation Routes International Journal of Experimental Pathology. Dec, 2007 | Pubmed ID: 18039277 Cross-protection Against H5N1 Influenza Virus Infection is Afforded by Intranasal Inoculation with Seasonal Trivalent Inactivated Influenza Vaccine The Journal of Infectious Diseases. Nov, 2007 | Pubmed ID: 17922395 Intranasal Immunization with H5N1 Vaccine Plus Poly I:Poly C12U, a Toll-like Receptor Agonist, Protects Mice Against Homologous and Heterologous Virus Challenge Microbes and Infection. Sep, 2007 | Pubmed ID: 17890128 Prophylactic Effects of Chitin Microparticles on Highly Pathogenic H5N1 Influenza Virus Journal of Medical Virology. Jun, 2007 | Pubmed ID: 17457919 Development of a Mucosal Vaccine for Influenza Viruses: Preparation for a Potential Influenza Pandemic Expert Review of Vaccines. Apr, 2007 | Pubmed ID: 17408369 Participation of Both Host and Virus Factors in Induction of Severe Acute Respiratory Syndrome (SARS) in F344 Rats Infected with SARS Coronavirus Journal of Virology. Feb, 2007 | Pubmed ID: 17151094 Highly Attenuated Vaccinia Virus DIs As a Potential SARS Vaccine Advances in Experimental Medicine and Biology. 2006 | Pubmed ID: 17037603 Pathological and Virological Analyses of Severe Acute Respiratory Syndrome-associated Coronavirus Infections in Experimental Animals Advances in Experimental Medicine and Biology. 2006 | Pubmed ID: 17037588 Intranasal Administration of Adjuvant-combined Recombinant Influenza Virus HA Vaccine Protects Mice from the Lethal H5N1 Virus Infection Microbes and Infection. Oct, 2006 | Pubmed ID: 16968669 Tristetraprolin Inhibits HIV-1 Production by Binding to Genomic RNA Microbes and Infection. Sep, 2006 | Pubmed ID: 16935542 Protection Against Influenza Virus Infection by Intranasal Vaccine with Surf Clam Microparticles (SMP) As an Adjuvant Journal of Medical Virology. Jul, 2006 | Pubmed ID: 16721854 LC16m8, a Highly Attenuated Vaccinia Virus Vaccine Lacking Expression of the Membrane Protein B5R, Protects Monkeys from Monkeypox Journal of Virology. Jun, 2006 | Pubmed ID: 16698998 Induction of Protective Immunity Against Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection Using Highly Attenuated Recombinant Vaccinia Virus DIs Virology. Aug, 2006 | Pubmed ID: 16678878 Distribution of PrP(Sc) in Cattle with Bovine Spongiform Encephalopathy Slaughtered at Abattoirs in Japan Japanese Journal of Infectious Diseases. Apr, 2006 | Pubmed ID: 16632909 Thymus-derived Leukemia-lymphoma in Mice Transgenic for the Tax Gene of Human T-lymphotropic Virus Type I Nature Medicine. Apr, 2006 | Pubmed ID: 16550188 Dicer and Positive Charge of Proteins Decrease the Stability of RNA Containing the AU-rich Element of GM-CSF Biochemical and Biophysical Research Communications. Feb, 2006 | Pubmed ID: 16380083 An Attenuated LC16m8 Smallpox Vaccine: Analysis of Full-genome Sequence and Induction of Immune Protection Journal of Virology. Sep, 2005 | Pubmed ID: 16140764 Inhibitory Effect of Mizoribine and Ribavirin on the Replication of Severe Acute Respiratory Syndrome (SARS)-associated Coronavirus Antiviral Research. Jun, 2005 | Pubmed ID: 15911031 Synthetic Double-stranded RNA Poly(I:C) Combined with Mucosal Vaccine Protects Against Influenza Virus Infection Journal of Virology. Mar, 2005 | Pubmed ID: 15709010 Protection Against Influenza Virus Infection by Intranasal Administration of Hemagglutinin Vaccine with Chitin Microparticles As an Adjuvant Journal of Medical Virology. Jan, 2005 | Pubmed ID: 15543590 Differential Localization of Neurons Susceptible to Enterovirus 71 and Poliovirus Type 1 in the Central Nervous System of Cynomolgus Monkeys After Intravenous Inoculation The Journal of General Virology. Oct, 2004 | Pubmed ID: 15448361 BCL-6-positive Human Herpesvirus 8-associated Solid Lymphoma Arising from Liver and Spleen As Multiple Nodular Lesions Leukemia & Lymphoma. Oct, 2004 | Pubmed ID: 15370268 Nucleolin and the Packaging Signal, Psi, Promote the Budding of Human Immunodeficiency Virus Type-1 (HIV-1) Microbiology and Immunology. 2004 | Pubmed ID: 14978336 Topoisomerase I Dissociates Human Immunodeficiency Virus Type 1 Reverse Transcriptase from Genomic RNAs Biochemical and Biophysical Research Communications. Jan, 2004 | Pubmed ID: 14706652 Protection Against Influenza Virus Infection by Intranasal Administration of C3d-fused Hemagglutinin Vaccine. Nov, 2003 | Pubmed ID: 14575764 Cross-reactive Antigenicity of Nucleoproteins of Lyssaviruses Recognized by a Monospecific Antirabies Virus Nucleoprotein Antiserum on Paraffin Sections of Formalin-fixed Tissues Pathology International. Aug, 2003 | Pubmed ID: 12895231 Human Topoisomerase I Promotes HIV-1 Proviral DNA Synthesis: Implications for the Species Specificity and Cellular Tropism of HIV-1 Infection Proceedings of the National Academy of Sciences of the United States of America. Jul, 2003 | Pubmed ID: 12829794 Roles of Anti-hemagglutinin IgA and IgG Antibodies in Different Sites of the Respiratory Tract of Vaccinated Mice in Preventing Lethal Influenza Pneumonia Vaccine. Jun, 2003 | Pubmed ID: 12744867 Rapid Tumor Formation of Human T-cell Leukemia Virus Type 1-infected Cell Lines in Novel NOD-SCID/gammac(null) Mice: Suppression by an Inhibitor Against NF-kappaB Journal of Virology. May, 2003 | Pubmed ID: 12692230 Processing of the HTLV-II Envelope Precursor Glycoprotein Gp63 by Furin is Essential for Cell Fusion Activity AIDS Research and Human Retroviruses. Nov, 2002 | Pubmed ID: 12487813 Binding and Dissociation of Human Topoisomerase I with Hairpin-loop RNAs: Implications for the Regulation of HIV-1 Replication Biochemical and Biophysical Research Communications. Sep, 2002 | Pubmed ID: 12270136 Reconstitution of Cleavage of Human Immunodeficiency Virus Type-1 (HIV-1) RNAs Biochemical and Biophysical Research Communications. May, 2002 | Pubmed ID: 12051771 Topoisomerase I and ATP Activate CDNA Synthesis of Human Immunodeficiency Virus Type 1 Biochemical and Biophysical Research Communications. Jun, 2002 | Pubmed ID: 12051740 Protection Against Influenza Virus Infection in Polymeric Ig Receptor Knockout Mice Immunized Intranasally with Adjuvant-combined Vaccines Journal of Immunology (Baltimore, Md. : 1950). Mar, 2002 | Pubmed ID: 11884464 Persistent Infection of Influenza Virus in Irradiated Mice and Its Prevention by Intranasal Vaccination Vaccine. Jan, 2002 | Pubmed ID: 11803065 Protection Against Influenza Virus Infection by Nasal Vaccination in Advance of Sublethal Irradiation Vaccine. May, 2000 | Pubmed ID: 10775790 Identificação de Mouse e repertórios de anticorpo humano por sequenciamento de próxima geração Lin Sun1, Naoko Kono2, Hiroyuki Toh3, Hanbing Xue1, Kaori Sano4,5, Tadaki Suzuki4, Akira Ainai4, Yasuko Orba6, Junya Yamagishi7,8, Hideki Hasegawa4,5, Yoshimasa Takahashi9, Shigeyuki Itamura2, Kazuo Ohnishi9,10 1Graduate School of Life and Environmental Sciences, University of Tsukuba, 2Center for Influenza Virus Research, National Institute of Infectious Diseases, 3School of Science and Technology, Kwansei Gakuin University, 4Department of Pathology, National Institute of Infectious Diseases, 5Division of Infectious Diseases Pathology, Department of Global Infectious Diseases, Tohoku University Graduate School of Medicine, 6Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, 7Division of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido University, 8Global Station for Zoonosis Control, GI-CoRE, Hokkaido University, 9Department of Immunology, National Institute of Infectious Diseases, 10Faculty of Life and Environmental Sciences, University of Tsukuba JoVE 58804 Immunology and Infection
Identificação de Mouse e repertórios de anticorpo humano por sequenciamento de próxima geração Lin Sun1, Naoko Kono2, Hiroyuki Toh3, Hanbing Xue1, Kaori Sano4,5, Tadaki Suzuki4, Akira Ainai4, Yasuko Orba6, Junya Yamagishi7,8, Hideki Hasegawa4,5, Yoshimasa Takahashi9, Shigeyuki Itamura2, Kazuo Ohnishi9,10 1Graduate School of Life and Environmental Sciences, University of Tsukuba, 2Center for Influenza Virus Research, National Institute of Infectious Diseases, 3School of Science and Technology, Kwansei Gakuin University, 4Department of Pathology, National Institute of Infectious Diseases, 5Division of Infectious Diseases Pathology, Department of Global Infectious Diseases, Tohoku University Graduate School of Medicine, 6Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, 7Division of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido University, 8Global Station for Zoonosis Control, GI-CoRE, Hokkaido University, 9Department of Immunology, National Institute of Infectious Diseases, 10Faculty of Life and Environmental Sciences, University of Tsukuba JoVE 58804 Immunology and Infection