Hiroshi Ohno Laboratory for Epithelial Immunobiology RIKEN Research Center for Allergy and Immunology Biography Publications Institution JoVE Articles Hiroshi Ohno has not added a biography. If you are Hiroshi Ohno and would like to personalize this page please email our Author Liaison for assistance. Publications Epithelial Cell-Intrinsic Notch Signaling Plays an Essential Role in the Maintenance of Gut Immune Homeostasis Journal of Immunology (Baltimore, Md. : 1950). Jan, 2012 | Pubmed ID: 22279105 Structures of Hydrocarbon Hydrates During Formation with and Without Inhibitors The Journal of Physical Chemistry. A. Feb, 2012 | Pubmed ID: 22185460 AP1B Plays an Important Role in Intestinal Tumorigenesis with the Truncating Mutation of an APC Gene International Journal of Cancer. Journal International Du Cancer. Mar, 2012 | Pubmed ID: 21484796 Complete Genome Sequences of Rat and Mouse Segmented Filamentous Bacteria, a Potent Inducer of Th17 Cell Differentiation Cell Host & Microbe. Sep, 2011 | Pubmed ID: 21925114 Dissociation Behavior of C2H6 Hydrate at Temperatures Below the Ice Point: Melting to Liquid Water Followed by Ice Nucleation The Journal of Physical Chemistry. A. Aug, 2011 | Pubmed ID: 21744826 The Epithelia-specific Membrane Trafficking Factor AP-1B Controls Gut Immune Homeostasis in Mice Gastroenterology. Aug, 2011 | Pubmed ID: 21669204 Morphological and Compositional Characterization of Self-preserved Gas Hydrates by Low-vacuum Scanning Electron Microscopy Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Jun, 2011 | Pubmed ID: 21509926 CCR6hiCD11c(int) B Cells Promote M-cell Differentiation in Peyer's Patch International Immunology. Apr, 2011 | Pubmed ID: 21422150 [Biology of M Cells, a Unique Subset of Intestinal Epithelial Cells] Seikagaku. The Journal of Japanese Biochemical Society. Jan, 2011 | Pubmed ID: 21404619 Salmonella Septic Arthritis Following Total Knee Arthroplasty for Rheumatoid Arthritis in a Patient Receiving Etanercept Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association. Mar, 2011 | Pubmed ID: 21301900 Bifidobacteria Can Protect from Enteropathogenic Infection Through Production of Acetate Nature. Jan, 2011 | Pubmed ID: 21270894 SP600125 Inhibits Cap-dependent Translation Independently of the C-Jun N-terminal Kinase Pathway Cell Structure and Function. 2011 | Pubmed ID: 21263197 Bifidobacterium Kashiwanohense Sp. Nov., Isolated from Healthy Infant Faeces International Journal of Systematic and Evolutionary Microbiology. Nov, 2011 | Pubmed ID: 21148680 Dynamic Omics Approach Identifies Nutrition-mediated Microbial Interactions Journal of Proteome Research. Feb, 2011 | Pubmed ID: 21058740 Glycoprotein 2 (GP2): Grabbing the FimH Bacteria into M Cells for Mucosal Immunity Gut Microbes. Nov-Dec, 2010 | Pubmed ID: 21468225 Symmetric Stretching Vibration of CH4 in Clathrate Hydrate Structures Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Oct, 2010 | Pubmed ID: 20718071 M-Sec: Emerging Secrets of Tunneling Nanotube Formation Communicative & Integrative Biology. May, 2010 | Pubmed ID: 20714400 Interaction of Antifreeze Proteins with Hydrocarbon Hydrates Chemistry (Weinheim an Der Bergstrasse, Germany). Sep, 2010 | Pubmed ID: 20623806 New Monitoring Approach for Metabolic Dynamics in Microbial Ecosystems Using Stable-isotope-labeling Technologies Journal of Bioscience and Bioengineering. Jul, 2010 | Pubmed ID: 20541122 Towards a Green Hydrate Inhibitor: Imaging Antifreeze Proteins on Clathrates PloS One. 2010 | Pubmed ID: 20161789 Identification of TOSO/FAIM3 As an Fc Receptor for IgM International Immunology. Mar, 2010 | Pubmed ID: 20042454 M-Sec Promotes Membrane Nanotube Formation by Interacting with Ral and the Exocyst Complex Nature Cell Biology. Dec, 2009 | Pubmed ID: 19935652 Uptake Through Glycoprotein 2 of FimH(+) Bacteria by M Cells Initiates Mucosal Immune Response Nature. Nov, 2009 | Pubmed ID: 19907495 Random Walker Test: a Computerized Alternative to the Road-Map Test Behavior Research Methods. Nov, 2009 | Pubmed ID: 19897833 Identity of the Elusive IgM Fc Receptor (FcmuR) in Humans The Journal of Experimental Medicine. Nov, 2009 | Pubmed ID: 19858324 AP-1 and KIF13A Coordinate Endosomal Sorting and Positioning During Melanosome Biogenesis The Journal of Cell Biology. Oct, 2009 | Pubmed ID: 19841138 New Approach for M-cell-specific Molecules Screening by Comprehensive Transcriptome Analysis DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes. Aug, 2009 | Pubmed ID: 19675110 Evaluation and Characterization of Bacterial Metabolic Dynamics with a Novel Profiling Technique, Real-time Metabolotyping PloS One. 2009 | Pubmed ID: 19287504 Raman Studies of Methane-ethane Hydrate Metastability The Journal of Physical Chemistry. A. Mar, 2009 | Pubmed ID: 19209919 Non-visually Evoked Activity of Isthmo-optic Neurons in Awake, Head-unrestrained Quail Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale. Apr, 2009 | Pubmed ID: 19183972 Lack of Potassium Current in W309R Mutant KCNQ3 Channel Causing Benign Familial Neonatal Convulsions (BFNC) Epilepsy Research. Mar, 2009 | Pubmed ID: 19167866 [Membrane Traffic: Overview] Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. Dec, 2008 | Pubmed ID: 21162329 [Physiological Roles of Clathrin-associated Adaptor Protein (AP) Complexes] Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. Dec, 2008 | Pubmed ID: 21038602 Rats Harboring S284L Chrna4 Mutation Show Attenuation of Synaptic and Extrasynaptic GABAergic Transmission and Exhibit the Nocturnal Frontal Lobe Epilepsy Phenotype The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2008 | Pubmed ID: 19020039 Activation-induced Cytidine Deaminase Deficiency Causes Organ-specific Autoimmune Disease PloS One. 2008 | Pubmed ID: 18716662 Design and Synthesis of a Metabolically Stable and Potent Antitussive Agent, a Novel Delta Opioid Receptor Antagonist, TRK-851 Bioorganic & Medicinal Chemistry. Sep, 2008 | Pubmed ID: 18701308 Aberrant Trafficking of the High-affinity Choline Transporter in AP-3-deficient Mice The European Journal of Neuroscience. Jun, 2008 | Pubmed ID: 18554297 Barriers to Vaccination Among Japanese Medical Students: Focus Group Interviews Pediatrics International : Official Journal of the Japan Pediatric Society. Jun, 2008 | Pubmed ID: 18533941 Comprehensive Gene Expression Profiling of Peyer's Patch M Cells, Villous M-like Cells, and Intestinal Epithelial Cells Journal of Immunology (Baltimore, Md. : 1950). Jun, 2008 | Pubmed ID: 18523247 Comparative Genome Analysis of Lactobacillus Reuteri and Lactobacillus Fermentum Reveal a Genomic Island for Reuterin and Cobalamin Production DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes. Jun, 2008 | Pubmed ID: 18487258 Construction of a Biological Tissue Model Based on a Single-cell Model: a Computer Simulation of Metabolic Heterogeneity in the Liver Lobule Artificial Life. 2008 | Pubmed ID: 18171128 Psg18 is Specifically Expressed in Follicle-associated Epithelium Cell Structure and Function. 2007 | Pubmed ID: 17984568 Construction of an Open-access Database That Integrates Cross-reference Information from the Transcriptome and Proteome of Immune Cells Bioinformatics (Oxford, England). Nov, 2007 | Pubmed ID: 17893089 Mast Cells Appearing in Long-term Skeletal Muscle Cell Cultures of Rat Anatomical Record (Hoboken, N.J. : 2007). Nov, 2007 | Pubmed ID: 17853403 Splenic CD19-CD35+B220+ Cells Function As an Inducer of Follicular Dendritic Cell Network Formation Blood. Aug, 2007 | Pubmed ID: 17519390 Mutation Screening of AP3M2 in Japanese Epilepsy Patients Brain & Development. Sep, 2007 | Pubmed ID: 17293072 Ischemia Promotes Calpain-mediated Degradation of P120-catenin in SH-SY5Y Cells Biochemical and Biophysical Research Communications. Feb, 2007 | Pubmed ID: 17196166 Visualization of the Post-Golgi Trafficking of Multiphoton Photoactivated Transferrin Receptors Cell Structure and Function. 2006 | Pubmed ID: 17072087 Clathrin-associated Adaptor Protein Complexes Journal of Cell Science. Sep, 2006 | Pubmed ID: 16959901 CMRF-35-like Molecule-5 Constitutes Novel Paired Receptors, with CMRF-35-like Molecule-1, to Transduce Activation Signal Upon Association with FcRgamma International Immunology. Oct, 2006 | Pubmed ID: 16940041 CD300 Antigen Like Family Member G: A Novel Ig Receptor Like Protein Exclusively Expressed on Capillary Endothelium Biochemical and Biophysical Research Communications. Sep, 2006 | Pubmed ID: 16876123 Physiological Roles of Clathrin Adaptor AP Complexes: Lessons from Mutant Animals Journal of Biochemistry. Jun, 2006 | Pubmed ID: 16788044 Overview: Membrane Traffic in Multicellular Systems: More Than Just a Housekeeper Journal of Biochemistry. Jun, 2006 | Pubmed ID: 16788043 [Epithelial Cells As Sentinels in Mucosal Immune Barrier] Nihon RinshÅ Men'eki Gakkai Kaishi = Japanese Journal of Clinical Immunology. Feb, 2006 | Pubmed ID: 16505599 Foxl1-deficient Mice Exhibit Aberrant Epithelial Cell Positioning Resulting from Dysregulated EphB/EphrinB Expression in the Small Intestine American Journal of Physiology. Gastrointestinal and Liver Physiology. Jul, 2006 | Pubmed ID: 16469829 Cosmological Magnetic Field: a Fossil of Density Perturbations in the Early Universe Science (New York, N.Y.). Feb, 2006 | Pubmed ID: 16400110 The Membrane-bound Chemokine CXCL16 Expressed on Follicle-associated Epithelium and M Cells Mediates Lympho-epithelial Interaction in GALT Journal of Immunology (Baltimore, Md. : 1950). Jan, 2006 | Pubmed ID: 16365394 Affinity Identification of Delta-opioid Receptors Using Latex Nanoparticles Bioorganic & Medicinal Chemistry Letters. Jan, 2006 | Pubmed ID: 16216499 Distinct Gene Expression Profiles Characterize Cellular Phenotypes of Follicle-associated Epithelium and M Cells DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes. 2005 | Pubmed ID: 16303744 Clathrin Adaptor AP-2 is Essential for Early Embryonal Development Molecular and Cellular Biology. Nov, 2005 | Pubmed ID: 16227583 Magnetic Field Generation from Cosmological Perturbations Physical Review Letters. Sep, 2005 | Pubmed ID: 16197062 Oral Administration of Bifidobacterium Bifidum G9-1 Suppresses Total and Antigen Specific Immunoglobulin E Production in Mice Biological & Pharmaceutical Bulletin. Aug, 2005 | Pubmed ID: 16079493 Defective Function of GABA-containing Synaptic Vesicles in Mice Lacking the AP-3B Clathrin Adaptor The Journal of Cell Biology. Oct, 2004 | Pubmed ID: 15492041 Retinal Target Cells of the Centrifugal Projection from the Isthmo-optic Nucleus The Journal of Comparative Neurology. Aug, 2004 | Pubmed ID: 15248195 Reduction of SNAP25 in Acid Secretion Defect of Foxl1-/- Gastric Parietal Cells Biochemical and Biophysical Research Communications. Jul, 2004 | Pubmed ID: 15240114 Dynamics of Golgi Matrix Proteins After the Blockage of ER to Golgi Transport Journal of Biochemistry. Feb, 2004 | Pubmed ID: 15047722 Interaction of a Farnesylated Protein with Renal Type IIa Na/Pi Co-transporter in Response to Parathyroid Hormone and Dietary Phosphate The Biochemical Journal. Feb, 2004 | Pubmed ID: 14558883 Adaptor Protein Complexes As the Key Regulators of Protein Sorting in the Post-Golgi Network Cell Structure and Function. Oct, 2003 | Pubmed ID: 14745134 Membrane Traffic in the Post-Golgi Network: Toward a Better Understanding of the Higher Order Functioning Systems Cell Structure and Function. Oct, 2003 | Pubmed ID: 14745132 Identification of a Five-pass Transmembrane Protein Family Localizing in the Golgi Apparatus and the ER Biochemical and Biophysical Research Communications. Dec, 2003 | Pubmed ID: 14680843 Solid-phase Synthesis of Naltrindole Derivatives Using Fischer Indole Synthesis Based on One-pot Release and Cyclization Methodology Organic Letters. Apr, 2003 | Pubmed ID: 12688708 Alternative Splicing Regulates the Subcellular Localization of Divalent Metal Transporter 1 Isoforms Molecular Biology of the Cell. Dec, 2002 | Pubmed ID: 12475959 Recording Site Dependence of the Neuronal Spiking Statistics Bio Systems. Oct-Dec, 2002 | Pubmed ID: 12459306 Blockade by Ferrous Iron of Ca2+ Influx Through N-methyl-D-aspartate Receptor Channels in Immature Cultured Rat Cortical Neurons Journal of Neurochemistry. Oct, 2002 | Pubmed ID: 12358723 Neuronal Leucine-rich Repeat Protein-3 Amplifies MAPK Activation by Epidermal Growth Factor Through a Carboxyl-terminal Region Containing Endocytosis Motifs The Journal of Biological Chemistry. Nov, 2002 | Pubmed ID: 12297494 Differential Recognition of Tyrosine-based Basolateral Signals by AP-1B Subunit Mu1B in Polarized Epithelial Cells Molecular Biology of the Cell. Jul, 2002 | Pubmed ID: 12134076 The Polarized Epithelia-specific Mu 1B-adaptin Complements Mu 1A-deficiency in Fibroblasts EMBO Reports. May, 2002 | Pubmed ID: 11964383 Essential Role of S-adenosylmethionine Decarboxylase in Mouse Embryonic Development Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Jan, 2002 | Pubmed ID: 11856372 Dual Mechanisms of Ca(2+) Increases Elicited by N-methyl-D-aspartate in Immature and Mature Cultured Cortical Neurons Journal of Neuroscience Research. Jan, 2002 | Pubmed ID: 11782971 Starvation-induced Transcription Factor CREBH Negatively Governs Body Growth by Controlling GH Signaling FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. | Pubmed ID: 34042217 Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis Via SREBP Competitive Inhibition Cellular and Molecular Gastroenterology and Hepatology. | Pubmed ID: 33246135 Association of Colitis with Gut-microbiota Dysbiosis in Clathrin Adapter AP-1B Knockout Mice PloS One. | Pubmed ID: 32208434 CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms IScience. | Pubmed ID: 32151974 Impact of Spaceflight on the Murine Thymus and Mitigation by Exposure to Artificial Gravity During Spaceflight Scientific Reports. | Pubmed ID: 31882694 Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl-Chain Length and Hepatic Insulin Sensitivity in Mice Hepatology (Baltimore, Md.). | Pubmed ID: 31529722 Octacosanol and Policosanol Prevent High-fat Diet-induced Obesity and Metabolic Disorders by Activating Brown Adipose Tissue and Improving Liver Metabolism Scientific Reports. | Pubmed ID: 30914769 The Peroxisome Proliferator-Activated Receptor α (PPARα) Agonist Pemafibrate Protects Against Diet-Induced Obesity in Mice International Journal of Molecular Sciences. | Pubmed ID: 30041488 Transgenic Mice Overexpressing SREBP-1a in Male Ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance Endocrinology. | Pubmed ID: 29668871 Selective Peroxisome Proliferator-activated Receptor-α Modulator K-877 Efficiently Activates the Peroxisome Proliferator-activated Receptor-α Pathway and Improves Lipid Metabolism in Mice Journal of Diabetes Investigation. | Pubmed ID: 28084058 Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice PloS One. | Pubmed ID: 27333187 Hyperlipidemia and Hepatitis in Liver-specific CREB3L3 Knockout Mice Generated Using a One-step CRISPR/Cas9 System Scientific Reports. | Pubmed ID: 27291420 Absence of Elovl6 Attenuates Steatohepatitis but Promotes Gallstone Formation in a Lithogenic Diet-fed Ldlr(-/-) Mouse Model Scientific Reports. | Pubmed ID: 26619823 Application of a Mouse Ligated Peyer’s Patch Intestinal Loop Assay to Evaluate Bacterial Uptake by M cells Shinji Fukuda1, Koji Hase1, Hiroshi Ohno1 1Laboratory for Epithelial Immunobiology, RIKEN Research Center for Allergy and Immunology JoVE 3225 Immunology and Infection
Application of a Mouse Ligated Peyer’s Patch Intestinal Loop Assay to Evaluate Bacterial Uptake by M cells Shinji Fukuda1, Koji Hase1, Hiroshi Ohno1 1Laboratory for Epithelial Immunobiology, RIKEN Research Center for Allergy and Immunology JoVE 3225 Immunology and Infection