Holden T. Maecker Human Immune Monitoring Center, Institute for Immunity, Transplantation, and Infection Stanford University Biography Publications Institution JoVE Articles Holden T. Maecker has not added a biography. If you are Holden T. Maecker and would like to personalize this page please email our Author Liaison for assistance. Publications New Tools for Classification and Monitoring of Autoimmune Diseases Nature Reviews. Rheumatology. Jun, 2012 | Pubmed ID: 22647780 The Stanford Data Miner: a Novel Approach for Integrating and Exploring Heterogeneous Immunological Data Journal of Translational Medicine. 2012 | Pubmed ID: 22452993 Standardizing Immunophenotyping for the Human Immunology Project Nature Reviews. Immunology. Mar, 2012 | Pubmed ID: 22343568 Recommendations from the ISBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2011 | Pubmed ID: 21558394 Multiparameter Intracellular Cytokine Staining Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21116983 Quality Assurance of Intracellular Cytokine Staining Assays: Analysis of Multiple Rounds of Proficiency Testing Journal of Immunological Methods. Jan, 2011 | Pubmed ID: 20727897 A Model for Harmonizing Flow Cytometry in Clinical Trials Nature Immunology. Nov, 2010 | Pubmed ID: 20959798 New Technologies for Autoimmune Disease Monitoring Current Opinion in Endocrinology, Diabetes, and Obesity. Aug, 2010 | Pubmed ID: 20531181 "MIATA"-minimal Information About T Cell Assays Immunity. Oct, 2009 | Pubmed ID: 19833080 Multiparameter Flow Cytometry Monitoring of T Cell Responses Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19020838 Standardization and Optimization of Multiparameter Intracellular Cytokine Staining Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Nov, 2008 | Pubmed ID: 18612990 Precision and Linearity Targets for Validation of an IFNgamma ELISPOT, Cytokine Flow Cytometry, and Tetramer Assay Using CMV Peptides BMC Immunology. 2008 | Pubmed ID: 18366814 Development and Dynamics of Robust T-cell Responses to CML Under Imatinib Treatment Blood. Jun, 2008 | Pubmed ID: 18326818 Poor Predictive Value of Cytomegalovirus (CMV)-specific T Cell Assays for the Development of CMV Retinitis in Patients with AIDS Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Feb, 2008 | Pubmed ID: 18173357 An Analytical Workflow for Investigating Cytokine Profiles Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Apr, 2008 | Pubmed ID: 18163472 Results and Harmonization Guidelines from Two Large-scale International Elispot Proficiency Panels Conducted by the Cancer Vaccine Consortium (CVC/SVI) Cancer Immunology, Immunotherapy : CII. Mar, 2008 | Pubmed ID: 17721781 Functional T Cell Responses to Tumor Antigens in Breast Cancer Patients Have a Distinct Phenotype and Cytokine Signature Journal of Immunology (Baltimore, Md. : 1950). Aug, 2007 | Pubmed ID: 17675526 Phenotype and in Vitro Function of Mature MDDC Generated from Cryopreserved PBMC of Cancer Patients Are Equivalent to Those from Healthy Donors Journal of Immune Based Therapies and Vaccines. 2007 | Pubmed ID: 17477875 Protective Immunity to Cytomegalovirus (CMV) Retinitis in AIDS is Associated with CMV-specific T Cells That Express Interferon- Gamma and Interleukin-2 and Have a CD8+ Cell Early Maturational Phenotype The Journal of Infectious Diseases. Dec, 2006 | Pubmed ID: 17083038 Flow Cytometry Controls, Instrument Setup, and the Determination of Positivity Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Sep, 2006 | Pubmed ID: 16888771 IL-2 Production Correlates with Effector Cell Differentiation in HIV-specific CD8+ T Cells AIDS Research and Therapy. 2006 | Pubmed ID: 16859558 Immune Responses in the Draining Lymph Nodes Against Cancer: Implications for Immunotherapy Cancer Metastasis Reviews. Jun, 2006 | Pubmed ID: 16770535 Maximizing the Retention of Antigen Specific Lymphocyte Function After Cryopreservation Journal of Immunological Methods. Jan, 2006 | Pubmed ID: 16337957 Impact of Cryopreservation on Tetramer, Cytokine Flow Cytometry, and ELISPOT BMC Immunology. 2005 | Pubmed ID: 16026627 Standardization of Cytokine Flow Cytometry Assays BMC Immunology. 2005 | Pubmed ID: 15978127 Ex Vivo Analysis of T-cell Function Current Opinion in Immunology. Aug, 2005 | Pubmed ID: 15950444 Immune Dysfunction and Micrometastases in Women with Breast Cancer Breast Cancer Research and Treatment. May, 2005 | Pubmed ID: 15868444 Dysfunction of Simian Immunodeficiency Virus/simian Human Immunodeficiency Virus-induced IL-2 Expression by Central Memory CD4+ T Lymphocytes Journal of Immunology (Baltimore, Md. : 1950). Apr, 2005 | Pubmed ID: 15814700 Multicolor Flow Cytometric Analysis in SIV-infected Rhesus Macaque Methods in Cell Biology. 2004 | Pubmed ID: 15603441 Selecting Fluorochrome Conjugates for Maximum Sensitivity Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Dec, 2004 | Pubmed ID: 15536642 Analyzing T-cell Responses to Cytomegalovirus by Cytokine Flow Cytometry Human Immunology. May, 2004 | Pubmed ID: 15172449 Results of a Cytomegalovirus (CMV)-specific CD8+/interferon- Gamma+ Cytokine Flow Cytometry Assay Correlate with Clinical Evidence of Protective Immunity in Patients with AIDS with CMV Retinitis The Journal of Infectious Diseases. Apr, 2004 | Pubmed ID: 15073672 Cytokine Flow Cytometry: a Multiparametric Approach for Assessing Cellular Immune Responses to Viral Antigens Clinical Immunology (Orlando, Fla.). Mar, 2004 | Pubmed ID: 15047200 Persistent and Selective Deficiency of CD4+ T Cell Immunity to Cytomegalovirus in Immunocompetent Young Children Journal of Immunology (Baltimore, Md. : 1950). Mar, 2004 | Pubmed ID: 14978134 Cytokine Flow Cytometry Methods in Molecular Biology (Clifton, N.J.). 2004 | Pubmed ID: 14976362 Strong Cell-mediated Immune Responses Are Associated with the Maintenance of Low-level Viremia in Antiretroviral-treated Individuals with Drug-resistant Human Immunodeficiency Virus Type 1 The Journal of Infectious Diseases. Jan, 2004 | Pubmed ID: 14722897 T Cell Immunity to HIV: Defining Parameters of Protection Current HIV Research. Apr, 2003 | Pubmed ID: 15043207 TNF-alpha Detection Using a Flow Cytometric Assay to Determine Cellular Responses to Anthrax Vaccine Journal of Immunological Methods. Nov, 2003 | Pubmed ID: 14604550 Performance of Plate-based Cytokine Flow Cytometry with Automated Data Analysis BMC Immunology. Sep, 2003 | Pubmed ID: 12952557 Optimal Preparation of Rhesus Macaque Blood for Cytokine Flow Cytometric Analysis Cytometry. Part A : the Journal of the International Society for Analytical Cytology. May, 2003 | Pubmed ID: 12701130 Analysis of the Frequencies and of the Memory T Cell Phenotypes of Human CD8+ T Cells Specific for Influenza A Viruses The Journal of Infectious Diseases. Apr, 2003 | Pubmed ID: 12660922 Human CD81 Directly Enhances Th1 and Th2 Cell Activation, but Preferentially Induces Proliferation of Th2 Cells Upon Long-term Stimulation BMC Immunology. Feb, 2003 | Pubmed ID: 12597781 Increased Brain Size and Glial Cell Number in CD81-null Mice The Journal of Comparative Neurology. Nov, 2002 | Pubmed ID: 12357429 Epigenetic Changes in Tumor Fas Levels Determine Immune Escape and Response to Therapy Cancer Cell. Aug, 2002 | Pubmed ID: 12204534 Dynamics of CD4 and CD8 T Cell Responses to Cytomegalovirus in Healthy Human Donors The Journal of Infectious Diseases. Jul, 2002 | Pubmed ID: 12089657 Mass Cytometry: Protocol for Daily Tuning and Running Cell Samples on a CyTOF Mass Cytometer Michael D. Leipold1, Holden T. Maecker1 1Human Immune Monitoring Center, Institute for Immunity, Transplantation, and Infection, Stanford University JoVE 4398 Bioengineering
Mass Cytometry: Protocol for Daily Tuning and Running Cell Samples on a CyTOF Mass Cytometer Michael D. Leipold1, Holden T. Maecker1 1Human Immune Monitoring Center, Institute for Immunity, Transplantation, and Infection, Stanford University JoVE 4398 Bioengineering